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Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 41, 2007, Pages 16365-16370

Chimeric constructs endow the human CFTR Cl- channel with the gating behavior of murine CFTR

(11) Scott Ward, Toby S a Cai, Zhiwei a Dawson, Elizabeth S b Doherty, Ann b Da Paula, Ana Carina d Davidson, Heather b Porteous, David J b Wainwright, Brandon J c Amaral, Margarida D d,e Sheppard, David N a Boyd, A Christopher b

a UNIVERSITY OF BRISTOL (United Kingdom)

b UNIVERSITY OF EDINBURGH (United Kingdom)

c UNIVERSITY OF QUEENSLAND (Australia)

d NATIONAL INSTITUTE OF HEALTH DR RICARDO JORGE (Portugal)

e UNIVERSITY OF LISBON (Portugal)

Author keywords

ATP binding cassette transporter; Chloride ion channel; Cystic fibrosis; Rate equilibrium free energy relationships; Recombinational cloning

Indexed keywords

CHLORIDE CHANNEL; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CHIMERA; CHLORIDE CURRENT; DIMERIZATION; ELECTROPHYSIOLOGY; GENE CONSTRUCT; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION;

ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING SITES; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DIMERIZATION; DIPHOSPHATES; HUMANS; ION CHANNEL GATING; KINETICS; MICE; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SPECIES SPECIFICITY;

MURINAE;

EID: 36048936399 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.0701562104 Document Type: Article

Times cited : (38)

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