Characterization of defects in ion transport and tissue development in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-knockout rats

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Tuggle, Katherine L ^a,b   Birket, Susan E ^a,c   Cui, Xiaoxia ^d   Hong, Jeong ^a,e   Warren, Joe ^d   Reid, Lara ^d   Chambers, Andre ^d   Ji, Diana ^d   Gamber, Kevin ^d   Chu, Kengyeh K ^f   Tearney, Guillermo ^f   Tang, Li Ping ^a   Fortenberry, James A ^a   Du, Ming ^a,b   Cadillac, Joan M ^b   Bedwell, David M ^a,g   Rowe, Steven M ^a,c   Sorscher, Eric J ^a,c   Fanucchi, Michelle V ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c and Clinical Center   (United States)

^d SAGE Labs   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

^g University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENDONUCLEASE; UNCLASSIFIED DRUG; ZINC FINGER ENDONUCLEASE;

AIRWAY SURFACE LIQUID; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENERGY; BREEDING; CHANNEL GATING; CONTROLLED STUDY; CYSTIC FIBROSIS; DISEASE MODEL; EMBRYO; EXON; FEMALE; FUNCTION TEST; GENE DELETION; GENE DISRUPTION; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; ILEUM; ION TRANSPORT; KNOCKOUT GENE; KNOCKOUT RAT; MALE; NASAL POTENTIAL DIFFERENCE; NEWBORN; NONHUMAN; NOSE MUCUS; PATHOGENESIS; PERICILIARY LIQUID; PHENOTYPE; PROTEIN EXPRESSION; PUP (RODENT); RAT; RAT MODEL; RESPIRATORY SYSTEM; SUBMUCOSA; SUBMUCOSAL GLAND; TISSUE GROWTH; TRANSEPITHELIAL SHORT CIRCUIT CURRENT; VAS DEFERENS; WILD TYPE; ANATOMY AND HISTOLOGY; ANIMAL; DEFICIENCY; DENTITION; EPITHELIUM; GENE INACTIVATION; GROWTH, DEVELOPMENT AND AGING; HUMAN; MEMBRANE POTENTIAL; METABOLISM; MICROINJECTION; MOLECULAR GENETICS; MUCUS; NOSE; NUCLEOTIDE SEQUENCE; ORGANOGENESIS; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TRACHEA;

ANIMALS; BASE SEQUENCE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DENTITION; EPITHELIUM; FEMALE; GENE KNOCKOUT TECHNIQUES; HUMANS; ILEUM; ION CHANNEL GATING; ION TRANSPORT; MALE; MEMBRANE POTENTIALS; MICROINJECTIONS; MOLECULAR SEQUENCE DATA; MUCUS; NOSE; ORGANOGENESIS; RATS, SPRAGUE-DAWLEY; TRACHEA; VAS DEFERENS;

EID: 84897426911     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091253     Document Type: Article

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