-
2
-
-
84894068321
-
The path of anti-tuberculosis drugs: From blood to lesions to mycobacterial cells
-
V. Dartois The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells Nat. Rev. Microbiol. 2014 12 3 159 167
-
(2014)
Nat. Rev. Microbiol.
, vol.12
, Issue.3
, pp. 159-167
-
-
Dartois, V.1
-
3
-
-
84860247190
-
Revisiting the role of the granuloma in tuberculosis. Nature reviews
-
L. Ramakrishnan Revisiting the role of the granuloma in tuberculosis. Nature reviews Immunology 2012 12 5 352 366
-
(2012)
Immunology
, vol.12
, Issue.5
, pp. 352-366
-
-
Ramakrishnan, L.1
-
5
-
-
84875498895
-
The immune response in tuberculosis
-
A. O'Garra et al., The immune response in tuberculosis Annu. Rev. Immunol. 2013 31 475 527
-
(2013)
Annu. Rev. Immunol.
, vol.31
, pp. 475-527
-
-
O'Garra, A.1
-
6
-
-
33646143975
-
Lessons from experimental Mycobacterium tuberculosis infections
-
J. L. Flynn Lessons from experimental Mycobacterium tuberculosis infections Microbes Infect. 2006 8 4 1179 1188
-
(2006)
Microbes Infect.
, vol.8
, Issue.4
, pp. 1179-1188
-
-
Flynn, J.L.1
-
7
-
-
85179220512
-
Pulmonary Tuberculosis in Monkeys
-
ed. V. D. J. Leong and T. Dick, CRC Press, Taylor & Francis
-
J. L. Flynn and E. Klein, Pulmonary Tuberculosis in Monkeys, in A Color Atlas of Comparative Pulmonary Tuberculosis Histopathology, ed., V. D. J. Leong, and, T. Dick, CRC Press, Taylor & Francis, 2011, pp. 83-106
-
(2011)
A Color Atlas of Comparative Pulmonary Tuberculosis Histopathology
, pp. 83-106
-
-
Flynn, J.L.1
Klein, E.2
-
8
-
-
77956216718
-
Understanding latent tuberculosis: A moving target
-
P. L. Lin J. L. Flynn Understanding latent tuberculosis: a moving target J. Immunol. 2010 185 1 15 22
-
(2010)
J. Immunol.
, vol.185
, Issue.1
, pp. 15-22
-
-
Lin, P.L.1
Flynn, J.L.2
-
9
-
-
84890072918
-
TB or not TB: That is no longer the question
-
R. L. Modlin B. R. Bloom TB or not TB: that is no longer the question Sci. Transl. Med. 2013 5 213 213sr6
-
(2013)
Sci. Transl. Med.
, vol.5
, Issue.213
, pp. 213sr6
-
-
Modlin, R.L.1
Bloom, B.R.2
-
10
-
-
84891853921
-
Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing
-
P. L. Lin et al., Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing Nat. Med. 2014 20 1 75 79
-
(2014)
Nat. Med.
, vol.20
, Issue.1
, pp. 75-79
-
-
Lin, P.L.1
-
11
-
-
33745622432
-
Early events in Mycobacterium tuberculosis infection in cynomolgus macaques
-
P. L. Lin et al., Early events in Mycobacterium tuberculosis infection in cynomolgus macaques Infect. Immun. 2006 74 7 3790 3803
-
(2006)
Infect. Immun.
, vol.74
, Issue.7
, pp. 3790-3803
-
-
Lin, P.L.1
-
12
-
-
70349427123
-
Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model
-
P. L. Lin et al., Quantitative comparison of active and latent tuberculosis in the cynomolgus macaque model Infect. Immun. 2009 77 10 4631 4642
-
(2009)
Infect. Immun.
, vol.77
, Issue.10
, pp. 4631-4642
-
-
Lin, P.L.1
-
13
-
-
79961172115
-
Latent tuberculosis: What the host sees?
-
H. P. Gideon J. L. Flynn Latent tuberculosis: what the host "sees"? Immunol. Res. 2011 50 2-3 202 212
-
(2011)
Immunol. Res.
, vol.50
, Issue.23
, pp. 202-212
-
-
Gideon, H.P.1
Flynn, J.L.2
-
14
-
-
84880273351
-
Multi-scale modeling predicts a balance of tumor necrosis factor-alpha and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection
-
N. A. Cilfone et al., Multi-scale modeling predicts a balance of tumor necrosis factor-alpha and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection PLoS One 2013 8 7 e68680
-
(2013)
PLoS One
, vol.8
, Issue.7
, pp. e68680
-
-
Cilfone, N.A.1
-
15
-
-
77954465946
-
TNF and IL-10 are major factors in modulation of the phagocytic cell environment in lung and lymph node in tuberculosis: A next-generation two-compartmental model
-
S. Marino et al., TNF and IL-10 are major factors in modulation of the phagocytic cell environment in lung and lymph node in tuberculosis: a next-generation two-compartmental model J. Theor. Biol. 2010 265 4 586 598
-
(2010)
J. Theor. Biol.
, vol.265
, Issue.4
, pp. 586-598
-
-
Marino, S.1
-
16
-
-
0035253576
-
A model to predict cell-mediated immune regulatory mechanisms during human infection with Mycobacterium tuberculosis
-
J. E. Wigginton D. Kirschner A model to predict cell-mediated immune regulatory mechanisms during human infection with Mycobacterium tuberculosis J. Immunol. 2001 166 3 1951 1967
-
(2001)
J. Immunol.
, vol.166
, Issue.3
, pp. 1951-1967
-
-
Wigginton, J.E.1
Kirschner, D.2
-
17
-
-
84882427707
-
Radiologic responses in cynomolgous macaques for assessing tuberculosis chemotherapy regimens
-
P. L. Lin et al., Radiologic responses in cynomolgous macaques for assessing tuberculosis chemotherapy regimens Antimicrob. Agents Chemother. 2013 57 9 4237 4244
-
(2013)
Antimicrob. Agents Chemother.
, vol.57
, Issue.9
, pp. 4237-4244
-
-
Lin, P.L.1
-
18
-
-
84875988455
-
The roles of immune memory and aging in protective immunity and endogenous reactivation of tuberculosis
-
G. Guzzetta D. Kirschner The roles of immune memory and aging in protective immunity and endogenous reactivation of tuberculosis PLoS One 2013 8 4 e60425
-
(2013)
PLoS One
, vol.8
, Issue.4
, pp. e60425
-
-
Guzzetta, G.1
Kirschner, D.2
-
19
-
-
70449705831
-
The spectrum of latent tuberculosis: Rethinking the biology and intervention strategies
-
C. E. Barry, 3rd et al., The spectrum of latent tuberculosis: rethinking the biology and intervention strategies Nat. Rev. Microbiol. 2009 7 12 845 855
-
(2009)
Nat. Rev. Microbiol.
, vol.7
, Issue.12
, pp. 845-855
-
-
Barry Iii., C.E.1
-
20
-
-
84859377308
-
Differential risk of tuberculosis reactivation among anti-TNF therapies is due to drug binding kinetics and permeability
-
M. Fallahi-Sichani et al., Differential risk of tuberculosis reactivation among anti-TNF therapies is due to drug binding kinetics and permeability J. Immunol. 2012 188 7 3169 3178
-
(2012)
J. Immunol.
, vol.188
, Issue.7
, pp. 3169-3178
-
-
Fallahi-Sichani, M.1
-
21
-
-
35748953415
-
Differences in reactivation of tuberculosis induced from anti-TNF treatments are based on bioavailability in granulomatous tissue
-
S. Marino et al., Differences in reactivation of tuberculosis induced from anti-TNF treatments are based on bioavailability in granulomatous tissue PLoS Comput. Biol. 2007 3 10 1909 1924
-
(2007)
PLoS Comput. Biol.
, vol.3
, Issue.10
, pp. 1909-1924
-
-
Marino, S.1
-
22
-
-
40749108974
-
Tumor necrosis factor blockade in chronic murine tuberculosis enhances granulomatous inflammation and disorganizes granulomas in the lungs
-
S. D. Chakravarty et al., Tumor necrosis factor blockade in chronic murine tuberculosis enhances granulomatous inflammation and disorganizes granulomas in the lungs Infect. Immun. 2008 76 3 916 926
-
(2008)
Infect. Immun.
, vol.76
, Issue.3
, pp. 916-926
-
-
Chakravarty, S.D.1
-
23
-
-
56749153497
-
Tumor necrosis factor blockers influence macrophage responses to Mycobacterium tuberculosis
-
J. Harris J. C. Hope J. Keane Tumor necrosis factor blockers influence macrophage responses to Mycobacterium tuberculosis J. Infect. Dis. 2008 198 12 1842 1850
-
(2008)
J. Infect. Dis.
, vol.198
, Issue.12
, pp. 1842-1850
-
-
Harris, J.1
Hope, J.C.2
Keane, J.3
-
24
-
-
2342468669
-
Granulomatous infectious diseases associated with tumor necrosis factor antagonists
-
R. S. Wallis et al., Granulomatous infectious diseases associated with tumor necrosis factor antagonists Clin. Infect. Dis. 2004 38 9 1261 1265
-
(2004)
Clin. Infect. Dis.
, vol.38
, Issue.9
, pp. 1261-1265
-
-
Wallis, R.S.1
-
25
-
-
0037441632
-
American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America: Treatment of Tuberculosis
-
H. M. Blumberg et al., American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America: Treatment of Tuberculosis Am. J. Respir. Crit. Care Med. 2003 167 4 603 662
-
(2003)
Am. J. Respir. Crit. Care Med.
, vol.167
, Issue.4
, pp. 603-662
-
-
Blumberg, H.M.1
-
27
-
-
0347091999
-
M. Tuberculosis persistence, latency, and drug tolerance
-
J. E. Gomez J. D. McKinney M. tuberculosis persistence, latency, and drug tolerance Tuberculosis 2004 84 1-2 29 44
-
(2004)
Tuberculosis
, vol.84
, Issue.12
, pp. 29-44
-
-
Gomez, J.E.1
McKinney, J.D.2
-
28
-
-
77957229965
-
The potent bactericidal activity of streptomycin in the guinea pig model of tuberculosis ceases due to the presence of persisters
-
Z. Ahmad et al., The potent bactericidal activity of streptomycin in the guinea pig model of tuberculosis ceases due to the presence of persisters J. Antimicrob. Chemother. 2010 65 10 2172 2175
-
(2010)
J. Antimicrob. Chemother.
, vol.65
, Issue.10
, pp. 2172-2175
-
-
Ahmad, Z.1
-
29
-
-
33947666691
-
Why is long-term therapy required to cure tuberculosis?
-
L. E. Connolly P. H. Edelstein L. Ramakrishnan Why is long-term therapy required to cure tuberculosis? PLoS Med. 2007 4 3 e120
-
(2007)
PLoS Med.
, vol.4
, Issue.3
, pp. e120
-
-
Connolly, L.E.1
Edelstein, P.H.2
Ramakrishnan, L.3
-
30
-
-
0031886212
-
How drug resistance emerges as a result of poor compliance during short course chemotherapy for tuberculosis
-
D. A. Mitchison How drug resistance emerges as a result of poor compliance during short course chemotherapy for tuberculosis Int. J. Tuberc. Lung Dis. 1998 2 1 10 15
-
(1998)
Int. J. Tuberc. Lung Dis.
, vol.2
, Issue.1
, pp. 10-15
-
-
Mitchison, D.A.1
-
31
-
-
0028274105
-
The effect of directly observed therapy on the rates of drug resistance and relapse in tuberculosis
-
S. E. Weis et al., The effect of directly observed therapy on the rates of drug resistance and relapse in tuberculosis N. Engl. J. Med. 1994 330 17 1179 1184
-
(1994)
N. Engl. J. Med.
, vol.330
, Issue.17
, pp. 1179-1184
-
-
Weis, S.E.1
-
32
-
-
80054123332
-
Treatment of tuberculosis and optimal dosing schedules
-
K. C. Chang et al., Treatment of tuberculosis and optimal dosing schedules Thorax 2011 66 11 997 1007
-
(2011)
Thorax
, vol.66
, Issue.11
, pp. 997-1007
-
-
Chang, K.C.1
-
33
-
-
33750873908
-
Schedule or dosage? the need to perfect intermittent regimens for tuberculosis
-
C. Saltini Schedule or dosage? The need to perfect intermittent regimens for tuberculosis Am. J. Respir. Crit. Care Med. 2006 174 10 1067 1068
-
(2006)
Am. J. Respir. Crit. Care Med.
, vol.174
, Issue.10
, pp. 1067-1068
-
-
Saltini, C.1
-
34
-
-
84877267006
-
Advances in the development of new tuberculosis drugs and treatment regimens
-
A. Zumla P. Nahid S. T. Cole Advances in the development of new tuberculosis drugs and treatment regimens Nat. Rev. Drug Discovery 2013 12 5 388 404
-
(2013)
Nat. Rev. Drug Discovery
, vol.12
, Issue.5
, pp. 388-404
-
-
Zumla, A.1
Nahid, P.2
Cole, S.T.3
-
35
-
-
77955478490
-
Identification of key processes that control tumor necrosis factor availability in a tuberculosis granuloma
-
M. Fallahi-Sichani et al., Identification of key processes that control tumor necrosis factor availability in a tuberculosis granuloma PLoS Comput. Biol. 2010 6 5 e1000778
-
(2010)
PLoS Comput. Biol.
, vol.6
, Issue.5
, pp. e1000778
-
-
Fallahi-Sichani, M.1
-
36
-
-
77954541844
-
Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing
-
S. Tay et al., Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing Nature 2010 466 7303 267 271
-
(2010)
Nature
, vol.466
, Issue.7303
, pp. 267-271
-
-
Tay, S.1
-
37
-
-
84873307871
-
Cytokine response is determined by duration of receptor and signal transducers and activators of transcription 3 (STAT3) activation
-
D. A. Braun M. Fribourg S. C. Sealfon Cytokine response is determined by duration of receptor and signal transducers and activators of transcription 3 (STAT3) activation J. Biol. Chem. 2013 288 5 2986 2993
-
(2013)
J. Biol. Chem.
, vol.288
, Issue.5
, pp. 2986-2993
-
-
Braun, D.A.1
Fribourg, M.2
Sealfon, S.C.3
-
38
-
-
0035877017
-
Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response
-
E. Giacomini et al., Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response J. Immunol. 2001 166 12 7033 7041
-
(2001)
J. Immunol.
, vol.166
, Issue.12
, pp. 7033-7041
-
-
Giacomini, E.1
-
39
-
-
84856003520
-
Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4 T cells
-
R. Blomgran et al., Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4 T cells Cell Host Microbe 2012 11 1 81 90
-
(2012)
Cell Host Microbe
, vol.11
, Issue.1
, pp. 81-90
-
-
Blomgran, R.1
-
40
-
-
0033965118
-
Apoptosis in mycobacterium tuberculosis infection in mice exhibiting varied immunopathology
-
V. E. Watson et al., Apoptosis in mycobacterium tuberculosis infection in mice exhibiting varied immunopathology J. Pathol. 2000 190 2 211 220
-
(2000)
J. Pathol.
, vol.190
, Issue.2
, pp. 211-220
-
-
Watson, V.E.1
-
41
-
-
84866528687
-
SOCS3 deficiency promotes M1 macrophage polarization and inflammation
-
H. Qin et al., SOCS3 deficiency promotes M1 macrophage polarization and inflammation J. Immunol. 2012 189 7 3439 3448
-
(2012)
J. Immunol.
, vol.189
, Issue.7
, pp. 3439-3448
-
-
Qin, H.1
-
42
-
-
84899096894
-
Microfluidic source-sink model reveals effects of biophysically distinct CXCL12 isoforms in breast cancer chemotaxis
-
S. P. Cavnar et al., Microfluidic source-sink model reveals effects of biophysically distinct CXCL12 isoforms in breast cancer chemotaxis Integr. Biol. 2014 6 5 564 576
-
(2014)
Integr. Biol.
, vol.6
, Issue.5
, pp. 564-576
-
-
Cavnar, S.P.1
-
43
-
-
84880126124
-
Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms
-
J. T. Mattila et al., Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms J. Immunol. 2013 191 2 773 784
-
(2013)
J. Immunol.
, vol.191
, Issue.2
, pp. 773-784
-
-
Mattila, J.T.1
-
45
-
-
58149083837
-
The role of the granuloma in expansion and dissemination of early tuberculous infection
-
J. M. Davis L. Ramakrishnan The role of the granuloma in expansion and dissemination of early tuberculous infection Cell 2009 136 1 37 49
-
(2009)
Cell
, vol.136
, Issue.1
, pp. 37-49
-
-
Davis, J.M.1
Ramakrishnan, L.2
-
46
-
-
46249108568
-
Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates
-
L. E. Via et al., Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates Infect. Immun. 2008 76 6 2333 2340
-
(2008)
Infect. Immun.
, vol.76
, Issue.6
, pp. 2333-2340
-
-
Via, L.E.1
-
47
-
-
84924184136
-
A systems biology approach for understanding granuloma formation and function in tuberculosis
-
ed. D. Beste, A. Kierzek and J. McFadden, Springer
-
M. Fallahi-Sichani, et al., A systems biology approach for understanding granuloma formation and function in tuberculosis, in Systems biology of tuberculosis, ed., D. Beste, A. Kierzek, and, J. McFadden, Springer, 2013
-
(2013)
Systems Biology of Tuberculosis
-
-
Fallahi-Sichani, M.1
-
48
-
-
79953194081
-
Multiscale computational modeling reveals a critical role for TNF-alpha receptor 1 dynamics in tuberculosis granuloma formation
-
M. Fallahi-Sichani et al., Multiscale computational modeling reveals a critical role for TNF-alpha receptor 1 dynamics in tuberculosis granuloma formation J. Immunol. 2011 186 6 3472 3483
-
(2011)
J. Immunol.
, vol.186
, Issue.6
, pp. 3472-3483
-
-
Fallahi-Sichani, M.1
-
49
-
-
84866354551
-
NF-kappaB Signaling Dynamics Play a Key Role in Infection Control in Tuberculosis
-
M. Fallahi-Sichani D. E. Kirschner J. J. Linderman NF-kappaB Signaling Dynamics Play a Key Role in Infection Control in Tuberculosis Front. Physiol. 2012 3 170
-
(2012)
Front. Physiol.
, vol.3
, pp. 170
-
-
Fallahi-Sichani, M.1
Kirschner, D.E.2
Linderman, J.J.3
-
50
-
-
65449166781
-
Synergy between individual TNF-dependent functions determines granuloma performance for controlling Mycobacterium tuberculosis infection
-
J. C. Ray J. L. Flynn D. E. Kirschner Synergy between individual TNF-dependent functions determines granuloma performance for controlling Mycobacterium tuberculosis infection J. Immunol. 2009 182 6 3706 3717
-
(2009)
J. Immunol.
, vol.182
, Issue.6
, pp. 3706-3717
-
-
Ray, J.C.1
Flynn, J.L.2
Kirschner, D.E.3
-
51
-
-
6344281115
-
Identifying control mechanisms of granuloma formation during M. Tuberculosis infection using an agent-based model
-
J. L. Segovia-Juarez S. Ganguli D. Kirschner Identifying control mechanisms of granuloma formation during M. tuberculosis infection using an agent-based model J. Theor. Biol. 2004 231 3 357 376
-
(2004)
J. Theor. Biol.
, vol.231
, Issue.3
, pp. 357-376
-
-
Segovia-Juarez, J.L.1
Ganguli, S.2
Kirschner, D.3
-
52
-
-
84920459654
-
Computational modeling predicts interleukin-10 control of lesion sterilization by balancing early host-immunity-mediated antimicrobial responses with caseation during mycobacterium tuberculosis infection
-
N. A. Cilfone et al., Computational modeling predicts interleukin-10 control of lesion sterilization by balancing early host-immunity-mediated antimicrobial responses with caseation during mycobacterium tuberculosis infection J. Immunol. 2015 194 2 664 677
-
(2015)
J. Immunol.
, vol.194
, Issue.2
, pp. 664-677
-
-
Cilfone, N.A.1
-
53
-
-
84919495222
-
Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection
-
S. Marino et al., Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection Infect. Immun. 2014 83 1 324 338
-
(2014)
Infect. Immun.
, vol.83
, Issue.1
, pp. 324-338
-
-
Marino, S.1
-
54
-
-
84925484533
-
Strategies for efficient numerical implementation of hybrid multi-scale agent-based models to describe biological systems
-
N. A. Cilfone D. E. Kirschner J. J. Linderman Strategies for efficient numerical implementation of hybrid multi-scale agent-based models to describe biological systems Cell. Mol. Bioeng. 2014 8 1 119 136
-
(2014)
Cell. Mol. Bioeng.
, vol.8
, Issue.1
, pp. 119-136
-
-
Cilfone, N.A.1
Kirschner, D.E.2
Linderman, J.J.3
-
55
-
-
84902658640
-
Tuneable resolution as a systems biology approach for multi-scale, multi-compartment computational models
-
D. E. Kirschner et al., Tuneable resolution as a systems biology approach for multi-scale, multi-compartment computational models Wiley Interdiscip. Rev.: Syst. Biol. Med. 2014 6 4 289 309
-
(2014)
Wiley Interdiscip. Rev.: Syst. Biol. Med.
, vol.6
, Issue.4
, pp. 289-309
-
-
Kirschner, D.E.1
-
57
-
-
45449094504
-
A methodology for performing global uncertainty and sensitivity analysis in systems biology
-
S. Marino et al., A methodology for performing global uncertainty and sensitivity analysis in systems biology J. Theor. Biol. 2008 254 1 178 196
-
(2008)
J. Theor. Biol.
, vol.254
, Issue.1
, pp. 178-196
-
-
Marino, S.1
-
58
-
-
84919742532
-
A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment
-
E. Pienaar et al., A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment J. Theor. Biol. 2015 367 166 179
-
(2015)
J. Theor. Biol.
, vol.367
, pp. 166-179
-
-
Pienaar, E.1
-
59
-
-
84865540183
-
Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques
-
P. L. Lin et al., Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques Proc. Natl. Acad. Sci. U. S. A. 2012 109 35 14188 14193
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, Issue.35
, pp. 14188-14193
-
-
Lin, P.L.1
-
60
-
-
84455169868
-
Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions
-
M. C. Kjellsson et al., Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions Antimicrob. Agents Chemother. 2012 56 1 446 457
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, Issue.1
, pp. 446-457
-
-
Kjellsson, M.C.1
-
61
-
-
79958856545
-
Variability in the population pharmacokinetics of isoniazid in South African tuberculosis patients
-
J. J. Wilkins et al., Variability in the population pharmacokinetics of isoniazid in South African tuberculosis patients Br. J. Clin. Pharmacol. 2011 72 1 51 62
-
(2011)
Br. J. Clin. Pharmacol.
, vol.72
, Issue.1
, pp. 51-62
-
-
Wilkins, J.J.1
-
62
-
-
44449128516
-
Population pharmacokinetics of rifampin in pulmonary tuberculosis patients, including a semimechanistic model to describe variable absorption
-
J. J. Wilkins et al., Population pharmacokinetics of rifampin in pulmonary tuberculosis patients, including a semimechanistic model to describe variable absorption Antimicrob. Agents Chemother. 2008 52 6 2138 2148
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, Issue.6
, pp. 2138-2148
-
-
Wilkins, J.J.1
-
63
-
-
51349129159
-
Prediction of Tumour Tissue Diffusion Coefficients of Hypoxia-Activated Prodrugs from Physicochemical Parameters
-
F. B. Pruijn et al., Prediction of Tumour Tissue Diffusion Coefficients of Hypoxia-Activated Prodrugs from Physicochemical Parameters Aust. J. Chem. 2008 61 9 687 693
-
(2008)
Aust. J. Chem.
, vol.61
, Issue.9
, pp. 687-693
-
-
Pruijn, F.B.1
-
64
-
-
78751684937
-
In silico children and the glass mouse model: Clinical trial simulations to identify and individualize optimal isoniazid doses in children with tuberculosis
-
P. M. Jeena et al., In silico children and the glass mouse model: clinical trial simulations to identify and individualize optimal isoniazid doses in children with tuberculosis Antimicrob. Agents Chemother. 2011 55 2 539 545
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, Issue.2
, pp. 539-545
-
-
Jeena, P.M.1
-
65
-
-
0029132928
-
Comparison of activities of rifapentine and rifampin against Mycobacterium tuberculosis residing in human macrophages
-
N. Mor et al., Comparison of activities of rifapentine and rifampin against Mycobacterium tuberculosis residing in human macrophages Antimicrob. Agents Chemother. 1995 39 9 2073 2077
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, Issue.9
, pp. 2073-2077
-
-
Mor, N.1
-
66
-
-
0021781123
-
Antibiotic accumulation in human polymorphonuclear leucocytes and lymphocytes
-
A. Forsgren A. Bellahsene Antibiotic accumulation in human polymorphonuclear leucocytes and lymphocytes Scand. J. Infect. Dis., Suppl. 1985 44 16 23
-
(1985)
Scand. J. Infect. Dis., Suppl.
, vol.44
, pp. 16-23
-
-
Forsgren, A.1
Bellahsene, A.2
-
67
-
-
0036919977
-
Rifampicin concentrations in bronchial mucosa, epithelial lining fluid, alveolar macrophages and serum following a single 600 mg oral dose in patients undergoing fibre-optic bronchoscopy
-
H. M. Ziglam et al., Rifampicin concentrations in bronchial mucosa, epithelial lining fluid, alveolar macrophages and serum following a single 600 mg oral dose in patients undergoing fibre-optic bronchoscopy J. Antimicrob. Chemother. 2002 50 6 1011 1015
-
(2002)
J. Antimicrob. Chemother.
, vol.50
, Issue.6
, pp. 1011-1015
-
-
Ziglam, H.M.1
-
68
-
-
70350234894
-
A modeling analysis of the effects of molecular size and binding affinity on tumor targeting
-
M. M. Schmidt K. D. Wittrup A modeling analysis of the effects of molecular size and binding affinity on tumor targeting Mol. Cancer Ther. 2009 8 10 2861 2871
-
(2009)
Mol. Cancer Ther.
, vol.8
, Issue.10
, pp. 2861-2871
-
-
Schmidt, M.M.1
Wittrup, K.D.2
-
69
-
-
78149474564
-
Time-kill kinetics of anti-tuberculosis drugs, and emergence of resistance, in relation to metabolic activity of Mycobacterium tuberculosis
-
J. E. de Steenwinkel et al., Time-kill kinetics of anti-tuberculosis drugs, and emergence of resistance, in relation to metabolic activity of Mycobacterium tuberculosis J. Antimicrob. Chemother. 2010 65 12 2582 2589
-
(2010)
J. Antimicrob. Chemother.
, vol.65
, Issue.12
, pp. 2582-2589
-
-
De Steenwinkel, J.E.1
-
70
-
-
0037662753
-
Pharmacokinetics-pharmacodynamics of rifampin in an aerosol infection model of tuberculosis
-
R. Jayaram et al., Pharmacokinetics-pharmacodynamics of rifampin in an aerosol infection model of tuberculosis Antimicrob. Agents Chemother. 2003 47 7 2118 2124
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, Issue.7
, pp. 2118-2124
-
-
Jayaram, R.1
-
71
-
-
3343001838
-
Isoniazid pharmacokinetics-pharmacodynamics in an aerosol infection model of tuberculosis
-
R. Jayaram et al., Isoniazid pharmacokinetics-pharmacodynamics in an aerosol infection model of tuberculosis Antimicrob. Agents Chemother. 2004 48 8 2951 2957
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, Issue.8
, pp. 2951-2957
-
-
Jayaram, R.1
-
72
-
-
34447251840
-
Isoniazid bactericidal activity and resistance emergence: Integrating pharmacodynamics and pharmacogenomics to predict efficacy in different ethnic populations
-
T. Gumbo et al., Isoniazid bactericidal activity and resistance emergence: integrating pharmacodynamics and pharmacogenomics to predict efficacy in different ethnic populations Antimicrob. Agents Chemother. 2007 51 7 2329 2336
-
(2007)
Antimicrob. Agents Chemother.
, vol.51
, Issue.7
, pp. 2329-2336
-
-
Gumbo, T.1
-
73
-
-
84929163853
-
Systems Pharmacology Approach Toward the Design of Inhaled Formulations of Rifampicin and Isoniazid for Treatment of Tuberculosis
-
N. A. Cilfone et al., Systems Pharmacology Approach Toward the Design of Inhaled Formulations of Rifampicin and Isoniazid for Treatment of Tuberculosis CPT: Pharmacometrics Syst. Pharmacol. 2015 4 e22
-
(2015)
CPT: Pharmacometrics Syst. Pharmacol.
, vol.4
, pp. e22
-
-
Cilfone, N.A.1
-
74
-
-
79954611569
-
A hybrid multi-compartment model of granuloma formation and T cell priming in Tuberculosis
-
S. Marino M. El-Kebir D. Kirschner A hybrid multi-compartment model of granuloma formation and T cell priming in Tuberculosis J. Theor. Biol. 2011 280 1 50 62
-
(2011)
J. Theor. Biol.
, vol.280
, Issue.1
, pp. 50-62
-
-
Marino, S.1
El-Kebir, M.2
Kirschner, D.3
-
75
-
-
84895558372
-
Harnessing the heterogeneity of T cell differentiation fate to fine-tune generation of effector and memory T cells
-
C. Gong J. J. Linderman D. E. Kirschner Harnessing the heterogeneity of T cell differentiation fate to fine-tune generation of effector and memory T cells Front. Immunol. 2014 5 57 10.3389/fimmu.2014.00057
-
(2014)
Front. Immunol.
, vol.5
, Issue.57
-
-
Gong, C.1
Linderman, J.J.2
Kirschner, D.E.3
-
76
-
-
0027360333
-
An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection
-
J. L. Flynn et al., An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection J. Exp. Med. 1993 178 6 2249 2254
-
(1993)
J. Exp. Med.
, vol.178
, Issue.6
, pp. 2249-2254
-
-
Flynn, J.L.1
-
77
-
-
75749099727
-
Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model
-
P. L. Lin et al., Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model Arthritis Rheuma 2010 62 2 340 350
-
(2010)
Arthritis Rheuma
, vol.62
, Issue.2
, pp. 340-350
-
-
Lin, P.L.1
-
78
-
-
79953048089
-
Regulation and functions of the IL-10 family of cytokines in inflammation and disease
-
W. Ouyang et al., Regulation and functions of the IL-10 family of cytokines in inflammation and disease Annu. Rev. Immunol. 2011 29 71 109
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 71-109
-
-
Ouyang, W.1
-
79
-
-
0035062021
-
Interleukin-10 and the interleukin-10 receptor
-
K. W. Moore et al., Interleukin-10 and the interleukin-10 receptor Annu. Rev. Immunol. 2001 19 683 765
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 683-765
-
-
Moore, K.W.1
-
80
-
-
0025889036
-
Macrophage deactivation by interleukin 10
-
C. Bogdan Y. Vodovotz C. Nathan Macrophage deactivation by interleukin 10 J. Exp. Med. 1991 174 6 1549 1555
-
(1991)
J. Exp. Med.
, vol.174
, Issue.6
, pp. 1549-1555
-
-
Bogdan, C.1
Vodovotz, Y.2
Nathan, C.3
-
81
-
-
0033370663
-
Interleukin 10 produced by macrophages inoculated with Mycobacterium avium attenuates mycobacteria-induced apoptosis by reduction of TNF-alpha activity
-
M. K. Balcewicz-Sablinska H. Gan H. G. Remold Interleukin 10 produced by macrophages inoculated with Mycobacterium avium attenuates mycobacteria-induced apoptosis by reduction of TNF-alpha activity J. Infect. Dis. 1999 180 4 1230 1237
-
(1999)
J. Infect. Dis.
, vol.180
, Issue.4
, pp. 1230-1237
-
-
Balcewicz-Sablinska, M.K.1
Gan, H.2
Remold, H.G.3
-
82
-
-
61649094923
-
Lack of IL-10 alters inflammatory and immune responses during pulmonary Mycobacterium tuberculosis infection
-
D. M. Higgins et al., Lack of IL-10 alters inflammatory and immune responses during pulmonary Mycobacterium tuberculosis infection Tuberculosis 2009 89 2 149 157
-
(2009)
Tuberculosis
, vol.89
, Issue.2
, pp. 149-157
-
-
Higgins, D.M.1
-
83
-
-
79955102870
-
The role of IL-10 in immune regulation during M. Tuberculosis infection
-
P. S. Redford P. J. Murray A. O'Garra The role of IL-10 in immune regulation during M. tuberculosis infection Mucosal Immunol. 2011 4 3 261 270
-
(2011)
Mucosal Immunol.
, vol.4
, Issue.3
, pp. 261-270
-
-
Redford, P.S.1
Murray, P.J.2
O'Garra, A.3
-
84
-
-
34748854885
-
Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies
-
R. M. Savic et al., Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies J. Pharmacokinet. Pharmacodyn. 2007 34 5 711 726
-
(2007)
J. Pharmacokinet. Pharmacodyn.
, vol.34
, Issue.5
, pp. 711-726
-
-
Savic, R.M.1
-
85
-
-
4644287346
-
Pharmacodynamic functions: A multiparameter approach to the design of antibiotic treatment regimens
-
R. R. Regoes et al., Pharmacodynamic functions: a multiparameter approach to the design of antibiotic treatment regimens Antimicrob. Agents Chemother. 2004 48 10 3670 3676
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, Issue.10
, pp. 3670-3676
-
-
Regoes, R.R.1
-
87
-
-
84902167811
-
Exploring the collaboration between antibiotics and the immune response in the treatment of acute, self-limiting infections
-
P. Ankomah B. R. Levin Exploring the collaboration between antibiotics and the immune response in the treatment of acute, self-limiting infections Proc. Natl. Acad. Sci. U. S. A. 2014 111 23 8331 8338
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, Issue.23
, pp. 8331-8338
-
-
Ankomah, P.1
Levin, B.R.2
-
88
-
-
76849093957
-
New old challenges in tuberculosis: Potentially effective nanotechnologies in drug delivery
-
A. Sosnik et al., New old challenges in tuberculosis: potentially effective nanotechnologies in drug delivery Adv. Drug Delivery Rev. 2010 62 4-5 547 559
-
(2010)
Adv. Drug Delivery Rev.
, vol.62
, Issue.45
, pp. 547-559
-
-
Sosnik, A.1
-
89
-
-
70350228508
-
Inhaled drug delivery for tuberculosis therapy
-
P. Muttil C. Wang A. J. Hickey Inhaled drug delivery for tuberculosis therapy Pharm. Res. 2009 26 11 2401 2416
-
(2009)
Pharm. Res.
, vol.26
, Issue.11
, pp. 2401-2416
-
-
Muttil, P.1
Wang, C.2
Hickey, A.J.3
-
90
-
-
79551498057
-
Inhaled drug therapy for treatment of tuberculosis
-
A. Misra et al., Inhaled drug therapy for treatment of tuberculosis Tuberculosis 2011 91 1 71 81
-
(2011)
Tuberculosis
, vol.91
, Issue.1
, pp. 71-81
-
-
Misra, A.1
-
91
-
-
77958100679
-
Nanobead-based interventions for the treatment and prevention of tuberculosis
-
G. Griffiths et al., Nanobead-based interventions for the treatment and prevention of tuberculosis Nat. Rev. Microbiol. 2010 8 11 827 834
-
(2010)
Nat. Rev. Microbiol.
, vol.8
, Issue.11
, pp. 827-834
-
-
Griffiths, G.1
-
92
-
-
55849092853
-
Mathematical modeling of drug delivery
-
J. Siepmann F. Siepmann Mathematical modeling of drug delivery Int. J. Pharm. 2008 364 2 328 343
-
(2008)
Int. J. Pharm.
, vol.364
, Issue.2
, pp. 328-343
-
-
Siepmann, J.1
Siepmann, F.2
-
93
-
-
14744279591
-
Modeling of drug release from polymeric delivery systems - A review
-
D. G. Kanjickal S. T. Lopina Modeling of drug release from polymeric delivery systems-a review Crit. Rev. Ther. Drug Carrier Syst. 2004 21 5 345 386
-
(2004)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.21
, Issue.5
, pp. 345-386
-
-
Kanjickal, D.G.1
Lopina, S.T.2
-
94
-
-
33751183754
-
Mathematical modeling and simulation of drug release from microspheres: Implications to drug delivery systems
-
D. Y. Arifin L. Y. Lee C. H. Wang Mathematical modeling and simulation of drug release from microspheres: implications to drug delivery systems Adv. Drug Delivery Rev. 2006 58 12-13 1274 1325
-
(2006)
Adv. Drug Delivery Rev.
, vol.58
, Issue.1213
, pp. 1274-1325
-
-
Arifin, D.Y.1
Lee, L.Y.2
Wang, C.H.3
-
95
-
-
0034972610
-
Comparative pharmacokinetics and pharmacodynamics of the rifamycin antibacterials
-
W. J. Burman K. Gallicano C. Peloquin Comparative pharmacokinetics and pharmacodynamics of the rifamycin antibacterials Clin. Pharmacokinet. 2001 40 5 327 341
-
(2001)
Clin. Pharmacokinet.
, vol.40
, Issue.5
, pp. 327-341
-
-
Burman, W.J.1
Gallicano, K.2
Peloquin, C.3
-
96
-
-
84855467363
-
The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection
-
P. L. Lin et al., The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection J. Clin. Invest. 2012 122 1 303 314
-
(2012)
J. Clin. Invest.
, vol.122
, Issue.1
, pp. 303-314
-
-
Lin, P.L.1
-
97
-
-
84897583030
-
Recent advances towards tuberculosis control: Vaccines and biomarkers
-
J. Weiner, 3rd S. H. Kaufmann Recent advances towards tuberculosis control: vaccines and biomarkers J. Intern. Med. 2014 275 5 467 480
-
(2014)
J. Intern. Med.
, vol.275
, Issue.5
, pp. 467-480
-
-
Weiner Iii., J.1
Kaufmann, S.H.2
-
98
-
-
84906732814
-
Vaccine against tuberculosis: What's new?
-
C. Montagnani et al., Vaccine against tuberculosis: what's new? BMC Infect. Dis. 2014 14 suppl 1 S2
-
(2014)
BMC Infect. Dis.
, vol.14
, pp. S2
-
-
Montagnani, C.1
-
99
-
-
84882276233
-
Tuberculosis vaccines: Time to think about the next generation
-
S. H. Kaufmann Tuberculosis vaccines: time to think about the next generation Semin. Immunol. 2013 25 2 172 181
-
(2013)
Semin. Immunol.
, vol.25
, Issue.2
, pp. 172-181
-
-
Kaufmann, S.H.1
-
100
-
-
79751497607
-
A multistage tuberculosis vaccine that confers efficient protection before and after exposure
-
C. Aagaard et al., A multistage tuberculosis vaccine that confers efficient protection before and after exposure Nat. Med. 2011 17 2 189 194
-
(2011)
Nat. Med.
, vol.17
, Issue.2
, pp. 189-194
-
-
Aagaard, C.1
-
101
-
-
84905126638
-
Tuberculosis vaccines-rethinking the current paradigm
-
P. Andersen J. S. Woodworth Tuberculosis vaccines-rethinking the current paradigm Trends Immunol. 2014 35 8 387 395
-
(2014)
Trends Immunol.
, vol.35
, Issue.8
, pp. 387-395
-
-
Andersen, P.1
Woodworth, J.S.2
-
102
-
-
84880946832
-
Predicting lymph node output efficiency using systems biology
-
C. Gong et al., Predicting lymph node output efficiency using systems biology J. Theor. Biol. 2013 335C 169 184
-
(2013)
J. Theor. Biol.
, vol.335
, pp. 169-184
-
-
Gong, C.1
-
103
-
-
77951888203
-
Characterizing the dynamics of CD4+ T cell priming within a lymph node
-
J. J. Linderman et al., Characterizing the dynamics of CD4+ T cell priming within a lymph node J. Immunol. 2010 184 6 2873 2885
-
(2010)
J. Immunol.
, vol.184
, Issue.6
, pp. 2873-2885
-
-
Linderman, J.J.1
-
104
-
-
0029153736
-
High endothelial venules (HEVs): Specialized endothelium for lymphocyte migration
-
J. P. Girard T. A. Springer High endothelial venules (HEVs): specialized endothelium for lymphocyte migration Immunol. Today 1995 16 9 449 457
-
(1995)
Immunol. Today
, vol.16
, Issue.9
, pp. 449-457
-
-
Girard, J.P.1
Springer, T.A.2
-
105
-
-
33645289121
-
CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs
-
L. R. Shiow et al., CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs Nature 2006 440 7083 540 544
-
(2006)
Nature
, vol.440
, Issue.7083
, pp. 540-544
-
-
Shiow, L.R.1
-
106
-
-
51349123844
-
Modelling the effects of pre-exposure and post-exposure vaccines in tuberculosis control
-
C. P. Bhunu et al., Modelling the effects of pre-exposure and post-exposure vaccines in tuberculosis control J. Theor. Biol. 2008 254 3 633 649
-
(2008)
J. Theor. Biol.
, vol.254
, Issue.3
, pp. 633-649
-
-
Bhunu, C.P.1
-
107
-
-
34447317247
-
Investigating the metabolic capabilities of Mycobacterium tuberculosis H37Rv using the in silico strain iNJ661 and proposing alternative drug targets
-
N. Jamshidi B. O. Palsson Investigating the metabolic capabilities of Mycobacterium tuberculosis H37Rv using the in silico strain iNJ661 and proposing alternative drug targets BMC Syst. Biol. 2007 1 26
-
(2007)
BMC Syst. Biol.
, vol.1
, pp. 26
-
-
Jamshidi, N.1
Palsson, B.O.2
-
108
-
-
84874530185
-
Updating and curating metabolic pathways of TB
-
R. A. Slayden et al., Updating and curating metabolic pathways of TB Tuberculosis 2013 93 1 47 59
-
(2013)
Tuberculosis
, vol.93
, Issue.1
, pp. 47-59
-
-
Slayden, R.A.1
-
109
-
-
79960933284
-
(1)(3)C metabolic flux analysis identifies an unusual route for pyruvate dissimilation in mycobacteria which requires isocitrate lyase and carbon dioxide fixation
-
D. J. Beste et al., (1)(3)C metabolic flux analysis identifies an unusual route for pyruvate dissimilation in mycobacteria which requires isocitrate lyase and carbon dioxide fixation PLoS Pathog. 2011 7 7 e1002091
-
(2011)
PLoS Pathog.
, vol.7
, Issue.7
, pp. e1002091
-
-
Beste, D.J.1
-
110
-
-
84880506145
-
The Mycobacterium tuberculosis regulatory network and hypoxia
-
J. E. Galagan et al., The Mycobacterium tuberculosis regulatory network and hypoxia Nature 2013 499 7457 178 183
-
(2013)
Nature
, vol.499
, Issue.7457
, pp. 178-183
-
-
Galagan, J.E.1
-
111
-
-
84929183533
-
Probing Gene Regulatory Networks to Decipher Host-Pathogen Interactions
-
ed. J. McFadden, D. Beste and A. M. Kierzek, Springer
-
K. S. Rao, D. Kumar and S. Mande, Probing Gene Regulatory Networks to Decipher Host-Pathogen Interactions, in Systems biology of tuberculosis, ed., J. McFadden, D. Beste, and, A. M. Kierzek, Springer, 2013
-
(2013)
Systems Biology of Tuberculosis
-
-
Rao, K.S.1
Kumar, D.2
Mande, S.3
-
112
-
-
84883173541
-
(13)C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis
-
D. J. Beste et al., (13)C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis Chem. Biol. 2013 20 8 1012 1021
-
(2013)
Chem. Biol.
, vol.20
, Issue.8
, pp. 1012-1021
-
-
Beste, D.J.1
-
113
-
-
84881169742
-
Mining large-scale response networks reveals 'topmost activities' in Mycobacterium tuberculosis infection
-
A. Sambarey K. Prashanthi N. Chandra Mining large-scale response networks reveals 'topmost activities' in Mycobacterium tuberculosis infection Sci. Rep. 2013 3 2302
-
(2013)
Sci. Rep.
, vol.3
, pp. 2302
-
-
Sambarey, A.1
Prashanthi, K.2
Chandra, N.3
-
114
-
-
77249117661
-
A systems perspective of host-pathogen interactions: Predicting disease outcome in tuberculosis
-
K. Raman A. G. Bhat N. Chandra A systems perspective of host-pathogen interactions: predicting disease outcome in tuberculosis Mol. BioSyst. 2010 6 3 516 530
-
(2010)
Mol. BioSyst.
, vol.6
, Issue.3
, pp. 516-530
-
-
Raman, K.1
Bhat, A.G.2
Chandra, N.3
-
115
-
-
80053540908
-
Population pharmacokinetics and its role in anti-tuberculosis drug development and optimization of treatment
-
E. F. Egelund A. B. Barth C. A. Peloquin Population pharmacokinetics and its role in anti-tuberculosis drug development and optimization of treatment Curr. Pharm. Des. 2011 17 27 2889 2899
-
(2011)
Curr. Pharm. Des.
, vol.17
, Issue.27
, pp. 2889-2899
-
-
Egelund, E.F.1
Barth, A.B.2
Peloquin, C.A.3
-
116
-
-
84875191395
-
A physiologically based pharmacokinetic model of rifampin in mice
-
M. A. Lyons et al., A physiologically based pharmacokinetic model of rifampin in mice Antimicrob. Agents Chemother. 2013 57 4 1763 1771
-
(2013)
Antimicrob. Agents Chemother.
, vol.57
, Issue.4
, pp. 1763-1771
-
-
Lyons, M.A.1
-
117
-
-
84856077172
-
A physiologically based pharmacokinetic model for capreomycin
-
B. Reisfeld et al., A physiologically based pharmacokinetic model for capreomycin Antimicrob. Agents Chemother. 2012 56 2 926 934
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, Issue.2
, pp. 926-934
-
-
Reisfeld, B.1
-
118
-
-
79957790326
-
Mathematical modeling of pulmonary tuberculosis therapy: Insights from a prototype model with rifampin
-
S. Goutelle et al., Mathematical modeling of pulmonary tuberculosis therapy: insights from a prototype model with rifampin J. Theor. Biol. 2011 282 1 80 92
-
(2011)
J. Theor. Biol.
, vol.282
, Issue.1
, pp. 80-92
-
-
Goutelle, S.1
-
119
-
-
67649991190
-
Population modeling and Monte Carlo simulation study of the pharmacokinetics and antituberculosis pharmacodynamics of rifampin in lungs
-
S. Goutelle et al., Population modeling and Monte Carlo simulation study of the pharmacokinetics and antituberculosis pharmacodynamics of rifampin in lungs Antimicrob. Agents Chemother. 2009 53 7 2974 2981
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, Issue.7
, pp. 2974-2981
-
-
Goutelle, S.1
-
120
-
-
70350569315
-
A simple in vitro PK/PD model system to determine time-kill curves of drugs against Mycobacteria
-
N. R. Budha et al., A simple in vitro PK/PD model system to determine time-kill curves of drugs against Mycobacteria Tuberculosis 2009 89 5 378 385
-
(2009)
Tuberculosis
, vol.89
, Issue.5
, pp. 378-385
-
-
Budha, N.R.1
-
121
-
-
84907481004
-
A Model of Isoniazid Treatment of Tuberculosis
-
Y. Lemmer et al., A Model of Isoniazid Treatment of Tuberculosis J. Theor. Biol. 2014 363 367 373
-
(2014)
J. Theor. Biol.
, vol.363
, pp. 367-373
-
-
Lemmer, Y.1
-
122
-
-
0031057479
-
The population dynamics of antimicrobial chemotherapy
-
M. Lipsitch B. R. Levin The population dynamics of antimicrobial chemotherapy Antimicrob. Agents Chemother. 1997 41 2 363 373
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, Issue.2
, pp. 363-373
-
-
Lipsitch, M.1
Levin, B.R.2
-
123
-
-
84860222515
-
Metabolic network analysis predicts efficacy of FDA-approved drugs targeting the causative agent of a neglected tropical disease
-
A. K. Chavali et al., Metabolic network analysis predicts efficacy of FDA-approved drugs targeting the causative agent of a neglected tropical disease BMC Syst. Biol. 2012 6 27
-
(2012)
BMC Syst. Biol.
, vol.6
, pp. 27
-
-
Chavali, A.K.1
-
124
-
-
84857999389
-
A metabolic network approach for the identification and prioritization of antimicrobial drug targets
-
A. K. Chavali et al., A metabolic network approach for the identification and prioritization of antimicrobial drug targets Trends Microbiol. 2012 20 3 113 123
-
(2012)
Trends Microbiol.
, vol.20
, Issue.3
, pp. 113-123
-
-
Chavali, A.K.1
-
125
-
-
84873093745
-
Mechanistic systems modeling to guide drug discovery and development
-
B. J. Schmidt J. A. Papin C. J. Musante Mechanistic systems modeling to guide drug discovery and development Drug Discovery Today 2013 18 3-4 116 127
-
(2013)
Drug Discovery Today
, vol.18
, Issue.34
, pp. 116-127
-
-
Schmidt, B.J.1
Papin, J.A.2
Musante, C.J.3
-
126
-
-
84903888878
-
Analysis of combination drug therapy to develop regimens with shortened duration of treatment for tuberculosis
-
G. L. Drusano et al., Analysis of combination drug therapy to develop regimens with shortened duration of treatment for tuberculosis PLoS One 2014 9 7 e101311
-
(2014)
PLoS One
, vol.9
, Issue.7
, pp. e101311
-
-
Drusano, G.L.1
-
127
-
-
79954595692
-
High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions
-
B. Prideaux et al., High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions Anal. Chem. 2011 83 6 2112 2118
-
(2011)
Anal. Chem.
, vol.83
, Issue.6
, pp. 2112-2118
-
-
Prideaux, B.1
-
128
-
-
84929183534
-
Mass spectrometry imaging of levofloxacin distribution in TB-infected pulmonary lesions by MALDI-MSI and continuous liquid microjunction surface sampling
-
B. Prideaux et al., Mass spectrometry imaging of levofloxacin distribution in TB-infected pulmonary lesions by MALDI-MSI and continuous liquid microjunction surface sampling Int. J. Mass Spectrom. 2015 377 699 708
-
(2015)
Int. J. Mass Spectrom.
, vol.377
, pp. 699-708
-
-
Prideaux, B.1
-
129
-
-
71849100552
-
Advances in immunotherapy for tuberculosis treatment
-
ix
-
G. J. Churchyard et al., Advances in immunotherapy for tuberculosis treatment Clin. Chest Med. 2009 30 4 769 782
-
(2009)
Clin. Chest Med.
, vol.30
, Issue.4
, pp. 769-782
-
-
Churchyard, G.J.1
-
130
-
-
34447256528
-
Immunotherapeutics for tuberculosis in experimental animals: Is there a common pathway activated by effective protocols?
-
G. A. Rook D. B. Lowrie R. Hernandez-Pando Immunotherapeutics for tuberculosis in experimental animals: is there a common pathway activated by effective protocols? J. Infect. Dis. 2007 196 2 191 198
-
(2007)
J. Infect. Dis.
, vol.196
, Issue.2
, pp. 191-198
-
-
Rook, G.A.1
Lowrie, D.B.2
Hernandez-Pando, R.3
-
131
-
-
21844433456
-
Reconsidering adjuvant immunotherapy for tuberculosis
-
R. S. Wallis Reconsidering adjuvant immunotherapy for tuberculosis Clin. Infect. Dis. 2005 41 2 201 208
-
(2005)
Clin. Infect. Dis.
, vol.41
, Issue.2
, pp. 201-208
-
-
Wallis, R.S.1
-
132
-
-
84874504575
-
The mutation rate of mycobacterial repetitive unit loci in strains of M. Tuberculosis from cynomolgus macaque infection
-
M. N. Ragheb et al., The mutation rate of mycobacterial repetitive unit loci in strains of M. tuberculosis from cynomolgus macaque infection BMC Genomics 2013 14 145
-
(2013)
BMC Genomics
, vol.14
, pp. 145
-
-
Ragheb, M.N.1
|