메뉴 건너뛰기




Volumn 6, Issue 5, 2014, Pages 564-576

Microfluidic source-sink model reveals effects of biophysically distinct CXCL12 isoforms in breast cancer chemotaxis

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR7; ISOPROTEIN; STROMAL CELL DERIVED FACTOR 1; STROMAL CELL DERIVED FACTOR 1BETA; STROMAL CELL DERIVED FACTOR 1GAMMA; UNCLASSIFIED DRUG;

EID: 84899096894     PISSN: 17579694     EISSN: 17579708     Source Type: Journal    
DOI: 10.1039/c4ib00015c     Document Type: Article
Times cited : (31)

References (62)
  • 2
    • 80052094283 scopus 로고    scopus 로고
    • Homeostatic chemokine receptors and organ-specific metastasis
    • A. M. Burkhardt B. Homey A. Zlotnik Homeostatic chemokine receptors and organ-specific metastasis Nat. Rev. Immunol. 2011 11 9 597 606
    • (2011) Nat. Rev. Immunol. , vol.11 , Issue.9 , pp. 597-606
    • Burkhardt, A.M.1    Homey, B.2    Zlotnik, A.3
  • 3
    • 82755194789 scopus 로고    scopus 로고
    • The chemokine system and cancer
    • F. R. Balkwill The chemokine system and cancer J. Pathol. 2012 226 2 148 157
    • (2012) J. Pathol. , vol.226 , Issue.2 , pp. 148-157
    • Balkwill, F.R.1
  • 4
    • 0034021267 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors in the pathogenesis of multiple sclerosis
    • G. X. Zhang C. M. Baker D. L. Kolson A. M. Rostami Chemokines and chemokine receptors in the pathogenesis of multiple sclerosis Mult. Scler. 2000 6 1 3 13 (Pubitemid 30175365)
    • (2000) Multiple Sclerosis , vol.6 , Issue.1 , pp. 3-13
    • Zhang, G.X.1    Baker, C.M.2    Kolson, D.L.3    Rostami, A.M.4
  • 7
    • 84857658430 scopus 로고    scopus 로고
    • The Role of Chemokines in Mesenchymal Stem Cell Homing to Myocardium
    • Y. Wu R. Zhao The Role of Chemokines in Mesenchymal Stem Cell Homing to Myocardium Stem Cell Rev. Rep. 2012 8 1 243 250
    • (2012) Stem Cell Rev. Rep. , vol.8 , Issue.1 , pp. 243-250
    • Wu, Y.1    Zhao, R.2
  • 8
    • 40749162773 scopus 로고    scopus 로고
    • Chemokine-mobilized adult stem cells; defining a better hematopoietic graft
    • DOI 10.1038/sj.leu.2405021, PII 2405021
    • S. Fukuda L. M. Pelus Chemokine-mobilized adult stem cells; defining a better hematopoietic graft Leukemia 2008 22 3 466 473 (Pubitemid 351386716)
    • (2008) Leukemia , vol.22 , Issue.3 , pp. 466-473
    • Pelus, L.M.1    Fukuda, S.2
  • 9
    • 70349453919 scopus 로고    scopus 로고
    • Fgf8 morphogen gradient forms by a source-sink mechanism with freely diffusing molecules
    • 10.1038/nature08391, Epub 2009 Sep 9
    • S. R. Yu M. Burkhardt M. Nowak J. Ries Z. Petrasek S. Scholpp P. Schwille M. Brand Fgf8 morphogen gradient forms by a source-sink mechanism with freely diffusing molecules Nature 2009 461 7263 533 536 10.1038/nature08391
    • (2009) Nature , vol.461 , Issue.7263 , pp. 533-536
    • Yu, S.R.1    Burkhardt, M.2    Nowak, M.3    Ries, J.4    Petrasek, Z.5    Scholpp, S.6    Schwille, P.7    Brand, M.8
  • 12
    • 6944255474 scopus 로고    scopus 로고
    • Endocytosis controls spreading and effective signaling range of Fgf8 protein
    • DOI 10.1016/j.cub.2004.09.084, PII S0960982204007481
    • S. Scholpp M. Brand Endocytosis controls spreading and effective signaling range of Fgf8 protein Curr. Biol. 2004 14 20 1834 1841 (Pubitemid 39408773)
    • (2004) Current Biology , vol.14 , Issue.20 , pp. 1834-1841
    • Scholpp, S.1    Brand, M.2
  • 14
    • 77955657351 scopus 로고    scopus 로고
    • Constitutive and chemokine-dependent internalization and recycling of CXCR7 in breast cancer cells to degrade chemokine ligands
    • K. Luker J. Steele L. Mihalko G. Luker Constitutive and chemokine-dependent internalization and recycling of CXCR7 in breast cancer cells to degrade chemokine ligands Oncogene 2010 29 4599 4610
    • (2010) Oncogene , vol.29 , pp. 4599-4610
    • Luker, K.1    Steele, J.2    Mihalko, L.3    Luker, G.4
  • 15
    • 84869087515 scopus 로고    scopus 로고
    • Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells
    • K. Luker S. Lewin L. Mihalko B. Schmidt J. Winkler N. Coggins D. Thomas G. Luker Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells Oncogene 2012 31 4750 4758
    • (2012) Oncogene , vol.31 , pp. 4750-4758
    • Luker, K.1    Lewin, S.2    Mihalko, L.3    Schmidt, B.4    Winkler, J.5    Coggins, N.6    Thomas, D.7    Luker, G.8
  • 17
    • 0029884416 scopus 로고    scopus 로고
    • Identification of the G protein-coupled receptor kinase phosphorylation sites in the human beta2-adrenergic receptor
    • Z. Fredericks J. Pitcher R. Lefkowitz Identification of the G protein-coupled receptor kinase phosphorylation sites in the human beta2-adrenergic receptor J. Biol. Chem. 1996 271 23 13796 13803
    • (1996) J. Biol. Chem. , vol.271 , Issue.23 , pp. 13796-13803
    • Fredericks, Z.1    Pitcher, J.2    Lefkowitz, R.3
  • 22
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • F. Balkwill Cancer and the chemokine network Nat. Rev. Cancer 2004 4 7 540 550 (Pubitemid 38868623)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.7 , pp. 540-550
    • Balkwill, F.1
  • 23
    • 2342591450 scopus 로고    scopus 로고
    • The significance of cancer cell expression of the chemokine receptor CXCR4
    • DOI 10.1016/j.semcancer.2003.10.003, PII S1044579X03000981
    • F. Balkwill The significance of cancer cell expression of the chemokine receptor CXCR4 Semin. Cancer Biol. 2004 14 3 171 179 (Pubitemid 38586742)
    • (2004) Seminars in Cancer Biology , vol.14 , Issue.3 , pp. 171-179
    • Balkwill, F.1
  • 25
    • 84886784063 scopus 로고    scopus 로고
    • Generation and Dynamics of an Endogenous, Self-Generated Signaling Gradient across a Migrating Tissue
    • G. Venkiteswaran S. W. Lewellis J. Wang E. Reynolds C. Nicholson H. Knaut Generation and Dynamics of an Endogenous, Self-Generated Signaling Gradient across a Migrating Tissue Cell 2013 155 3 674 687
    • (2013) Cell , vol.155 , Issue.3 , pp. 674-687
    • Venkiteswaran, G.1    Lewellis, S.W.2    Wang, J.3    Reynolds, E.4    Nicholson, C.5    Knaut, H.6
  • 28
    • 33646749900 scopus 로고    scopus 로고
    • Identification and expression of novel isoforms of human stromal cell-derived factor 1
    • L. Yu J. Cecil S. Peng J. Schrementi S. Kovacevic D. Paul E. Su J. Wang Identification and expression of novel isoforms of human stromal cell-derived factor 1 Gene 2006 374 174 179
    • (2006) Gene , vol.374 , pp. 174-179
    • Yu, L.1    Cecil, J.2    Peng, S.3    Schrementi, J.4    Kovacevic, S.5    Paul, D.6    Su, E.7    Wang, J.8
  • 29
    • 42549130865 scopus 로고    scopus 로고
    • The novel CXCL12gamma isoform encodes an unstructured cationic domain which regulates bioactivity and interaction with both glycosaminoglycans and CXCR4
    • C. Laguri R. Sadir P. Rueda F. Baleux P. Gans F. Arenzana-Seisdedos The novel CXCL12gamma isoform encodes an unstructured cationic domain which regulates bioactivity and interaction with both glycosaminoglycans and CXCR4 PLoS One 2007 2 e1110
    • (2007) PLoS One , vol.2 , pp. 1110
    • Laguri, C.1    Sadir, R.2    Rueda, P.3    Baleux, F.4    Gans, P.5    Arenzana-Seisdedos, F.6
  • 30
    • 0034118768 scopus 로고    scopus 로고
    • Cloning and characterization of SDF-1γ, a novel SDF-1 chemokine transcript with developmentally regulated expression in the nervous system
    • DOI 10.1046/j.1460-9568.2000.00048.x
    • M. Gleichmann C. Gillen M. Czardybon F. Bosse R. Greiner-Petter J. Auer H. W. Müller Cloning and characterization of SDF-1γ, a novel SDF-1 chemokine transcript with developmentally regulated expression in the nervous system Eur. J. Neurosci. 2000 12 6 1857 1866 (Pubitemid 30348825)
    • (2000) European Journal of Neuroscience , vol.12 , Issue.6 , pp. 1857-1866
    • Gleichmann, M.1    Gillen, C.2    Czardybon, M.3    Bosse, F.4    Greiner-Petter, R.5    Auer, J.6    Muller, H.W.7
  • 31
    • 45049088086 scopus 로고    scopus 로고
    • Relationships between glycosaminoglycan and receptor binding sites in chemokines - The CXCL12 example
    • C. Laguri F. Arenzana-Seisdedos H. Lortat-Jacob Relationships between glycosaminoglycan and receptor binding sites in chemokines - the CXCL12 example Carbohydr. Res. 2008 343 12 2018 2023
    • (2008) Carbohydr. Res. , vol.343 , Issue.12 , pp. 2018-2023
    • Laguri, C.1    Arenzana-Seisdedos, F.2    Lortat-Jacob, H.3
  • 34
    • 66849138510 scopus 로고    scopus 로고
    • Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells
    • J. Song S. Cavnar A. Walker K. Luker M. Gupta Y. Tung G. Luker S. Takayama Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells PLoS One 2009 4 6 e5756
    • (2009) PLoS One , vol.4 , Issue.6 , pp. 5756
    • Song, J.1    Cavnar, S.2    Walker, A.3    Luker, K.4    Gupta, M.5    Tung, Y.6    Luker, G.7    Takayama, S.8
  • 35
    • 49049108182 scopus 로고    scopus 로고
    • Imaging CXCR4 signaling with firefly luciferase complementation
    • K. Luker M. Gupta G. Luker Imaging CXCR4 signaling with firefly luciferase complementation Anal. Chem. 2008 80 14 5565 5573
    • (2008) Anal. Chem. , vol.80 , Issue.14 , pp. 5565-5573
    • Luker, K.1    Gupta, M.2    Luker, G.3
  • 37
    • 70149106504 scopus 로고    scopus 로고
    • Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7
    • K. Luker M. Gupta G. Luker Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7 Biotechniques 2009 47 1 625 632
    • (2009) Biotechniques , vol.47 , Issue.1 , pp. 625-632
    • Luker, K.1    Gupta, M.2    Luker, G.3
  • 39
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • DOI 10.1016/j.cell.2005.02.034, PII S0092867405002370
    • A. Orimo P. Gupta D. Sgroi F. Arenzana-Seisdedos T. Delaunay R. Naeem V. Carey A. Richardson R. Weinberg Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion Cell 2005 121 3 335 348 (Pubitemid 40692295)
    • (2005) Cell , vol.121 , Issue.3 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 41
    • 77949314287 scopus 로고    scopus 로고
    • A Chemokine Targets the Nucleus: Cxcl12-Gamma Isoform Localizes to the Nucleolus in Adult Mouse Heart
    • R. Torres J. C. Ramirez A Chemokine Targets the Nucleus: Cxcl12-Gamma Isoform Localizes to the Nucleolus in Adult Mouse Heart PLoS One 2009 4 10 e7570
    • (2009) PLoS One , vol.4 , Issue.10 , pp. 7570
    • Torres, R.1    Ramirez, J.C.2
  • 42
    • 34547093608 scopus 로고    scopus 로고
    • A naturally occurring splice variant of CXCL12/stromal cell-derived factor 1 is a potent human immunodeficiency virus type 1 inhibitor with weak chemotaxis and cell survival activities
    • DOI 10.1128/JVI.00268-07
    • J. Altenburg H. Broxmeyer Q. Jin S. Cooper S. Basu G. Alkhatib A naturally occurring splice variant of CXCL12/stromal cell-derived factor 1 is a potent human immunodeficiency virus type 1 inhibitor with weak chemotaxis and cell survival activities J. Virol. 2007 81 15 8140 8148 (Pubitemid 47101500)
    • (2007) Journal of Virology , vol.81 , Issue.15 , pp. 8140-8148
    • Altenburg, J.D.1    Broxmeyer, H.E.2    Jin, Q.3    Cooper, S.4    Basu, S.5    Alkhatib, G.6
  • 43
    • 77649209816 scopus 로고    scopus 로고
    • The potent anti-HIV activity of CXCL12γ correlates with efficient CXCR4 binding and internalization
    • J. Altenburg Q. Jin B. Alkhatib G. Aklhatib The potent anti-HIV activity of CXCL12γ correlates with efficient CXCR4 binding and internalization J. Virol. 2010 84 5 2563 2572
    • (2010) J. Virol. , vol.84 , Issue.5 , pp. 2563-2572
    • Altenburg, J.1    Jin, Q.2    Alkhatib, B.3    Aklhatib, G.4
  • 51
    • 34248168879 scopus 로고    scopus 로고
    • Structural and functional basis of CXCL12 (stromal cell-derived factor-1α) binding to heparin
    • DOI 10.1074/jbc.M608796200
    • J. Murphy Y. Cho A. Sachpatzidis C. Fan M. Hodsdon E. Lolis Structural and functional basis of CXCL12 (stromal cell-derived factor-1) binding to heparin J. Biol. Chem. 2007 282 13 10018 10027 (Pubitemid 47104591)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.13 , pp. 10018-10027
    • Murphy, J.W.1    Cho, Y.2    Sachpatzidis, A.3    Fan, C.4    Hodsdon, M.E.5    Lolis, E.6
  • 52
    • 0037147145 scopus 로고    scopus 로고
    • β-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation
    • DOI 10.1074/jbc.M207294200
    • Y. Sun Z. Cheng L. Ma G. Pei Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation J. Biol. Chem. 2002 277 51 49212 49219 (Pubitemid 36014350)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.51 , pp. 49212-49219
    • Sun, Y.1    Cheng, Z.2    Ma, L.3    Pei, G.4
  • 53
    • 57049126122 scopus 로고    scopus 로고
    • Sulfated oligosaccharides (heparin and fucoidan) binding and dimerization of stromal cell-derived factor-1 (SDF-1/CXCL 12) are coupled as evidenced by affinity CE-MS analysis
    • DOI 10.1093/glycob/cwn088
    • S. Fermas F. Gonnet A. Sutton N. Charnaux B. Mulloy Y. Du F. Baleux R. Daniel Sulfated oligosaccharides (heparin and fucoidan) binding and dimerization of stromal cell-derived factor-1 (SDF-1/CXCL 12) are coupled as evidenced by affinity CE-MS analysis Glycobiology 2008 18 12 1054 1064 (Pubitemid 352762840)
    • (2008) Glycobiology , vol.18 , Issue.12 , pp. 1054-1064
    • Fermas, S.1    Gonnet, F.2    Sutton, A.3    Charnaux, N.4    Mulloy, B.5    Du, Y.6    Baleux, F.7    Daniel, R.8
  • 54
    • 15244345079 scopus 로고    scopus 로고
    • The monomer-dimer equilibrium of stromal cell-derived factor-1 (CXCL 12) is altered by pH, phosphate, sulfate, and heparin
    • DOI 10.1110/ps.041219505
    • C. Veldkamp F. Peterson A. Pelzek B. Volkman The monomer-dimer equilibrium of stromal cell-derived factor-1 (CXCL 12) is altered by pH, phosphate, sulfate, and heparin Protein Sci. 2005 14 4 1071 1081 (Pubitemid 40389378)
    • (2005) Protein Science , vol.14 , Issue.4 , pp. 1071-1081
    • Veldkamp, C.T.1    Peterson, F.C.2    Pelzek, A.J.3    Volkman, B.F.4
  • 56
    • 7444220147 scopus 로고    scopus 로고
    • Aberrant and alternative splicing in cancer
    • DOI 10.1158/0008-5472.CAN-04-1910
    • J. P. Venables Aberrant and Alternative Splicing in Cancer Cancer Res. 2004 64 21 7647 7654 (Pubitemid 39446889)
    • (2004) Cancer Research , vol.64 , Issue.21 , pp. 7647-7654
    • Venables, J.P.1
  • 57
    • 0031668734 scopus 로고    scopus 로고
    • Tissue-specific expression pattern of vascular endothelial growth factor isoforms in the malignant transformation of lung and colon
    • DOI 10.1016/S0046-8177(98)90195-2
    • N. Cheung M. P. Wong S. T. Yuen S. Y. Leung L. P. Chung Tissue-specific expression pattern of vascular endothelial growth factor isoforms in the malignant transformation of lung and colon Hum. Pathol. 1998 29 9 910 914 (Pubitemid 28422038)
    • (1998) Human Pathology , vol.29 , Issue.9 , pp. 910-914
    • Cheung, N.1    Wong, M.P.2    Yuen, S.T.3    Leung, S.Y.4    Chung, L.P.5
  • 59
    • 84880264772 scopus 로고    scopus 로고
    • Cooperative roles of SDF-1α and EGF gradients on tumor cell migration revealed by a robust 3D microfluidic model
    • B. J. Kim P. Hannanta-Anan M. Chau Y. S. Kim M. A. Swartz M. Wu Cooperative roles of SDF-1α and EGF gradients on tumor cell migration revealed by a robust 3D microfluidic model PLoS One 2013 8 7 e68422
    • (2013) PLoS One , vol.8 , Issue.7 , pp. 68422
    • Kim, B.J.1    Hannanta-Anan, P.2    Chau, M.3    Kim, Y.S.4    Swartz, M.A.5    Wu, M.6
  • 60
    • 0345059766 scopus 로고    scopus 로고
    • Intravital imaging of cell movement in tumours
    • J. Condeelis J. Segall Intravital imaging of cell movement in tumours Nat. Rev. Cancer 2003 3 921 930 (Pubitemid 37500177)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.12 , pp. 921-930
    • Condeelis, J.1    Segall, J.E.2
  • 62
    • 84867255818 scopus 로고    scopus 로고
    • Homeostatic and Tissue Reparation Defaults in Mice Carrying Selective Genetic Invalidation of CXCL12/Proteoglycan Interactions Clinical Perspective
    • P. Rueda A. Richart A. Récalde P. Gasse J. Vilar C. Guérin H. Lortat-Jacob P. Vieira F. i. Baleux F. Chretien Homeostatic and Tissue Reparation Defaults in Mice Carrying Selective Genetic Invalidation of CXCL12/Proteoglycan Interactions Clinical Perspective Circulation 2012 126 15 1882 1895
    • (2012) Circulation , vol.126 , Issue.15 , pp. 1882-1895
    • Rueda, P.1    Richart, A.2    Récalde, A.3    Gasse, P.4    Vilar, J.5    Guérin, C.6    Lortat-Jacob, H.7    Vieira, P.8    Chretien, F.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.