TNF and IL-10 are major factors in modulation of the phagocytic cell environment in lung and lymph node in tuberculosis: A next-generation two-compartmental model

Journal of Theoretical Biology

Volumn 265, Issue 4, 2010, Pages 586-598

  Marino, Simeone ^a   Myers, Amy ^b   Flynn, JoAnne L ^b   Kirschner, Denise E ^a,c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c Center for Computational Medicine and Bioinformatics   (United States)

Author keywords

Classically and alternatively activated macrophages; DCs; Inflammation; Mathematical model

Indexed keywords

INTERLEUKIN 10; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; CELL ORGANELLE; IMMUNE RESPONSE; INFECTIOUS DISEASE; NUMERICAL MODEL; TUBERCULOSIS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BACTERIUM EXAMINATION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL POLARITY; CELL POPULATION; COLONY FORMING UNIT; COMPARTMENT MODEL; CONTROLLED STUDY; DENDRITIC CELL; DYNAMICS; IMMUNOMODULATION; LUNG ALVEOLUS MACROPHAGE; LUNG TUBERCULOSIS; LYMPH NODE; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHAGOCYTE; PREDICTION; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; UNCERTAINTY; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; CYTOLOGY; HUMAN; IMMUNOLOGY; LUNG; MICROBIOLOGY; PATHOLOGY; REPRODUCIBILITY; T LYMPHOCYTE; TUBERCULOSIS;

ANIMALS; CELL POLARITY; DENDRITIC CELLS; HUMANS; IMMUNOMODULATION; INTERLEUKIN-10; LUNG; LYMPH NODES; MACROPHAGES; MICE; MICE, INBRED C57BL; MODELS, IMMUNOLOGICAL; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTES; REPRODUCIBILITY OF RESULTS; T-LYMPHOCYTES; TUBERCULOSIS; TUMOR NECROSIS FACTOR-ALPHA;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

EID: 77954465946     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2010.05.012     Document Type: Article

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