-
1
-
-
0034529994
-
Latent Mycobacterium tuberculosis-persistence, patience, and winning by waiting
-
Manabe, Y. C. & Bishai, W. R. Latent Mycobacterium tuberculosis-persistence, patience, and winning by waiting. Nature Med. 6, 1327-1329 (2000).
-
(2000)
Nature Med.
, vol.6
, pp. 1327-1329
-
-
Manabe, Y.C.1
Bishai, W.R.2
-
2
-
-
0034977241
-
Tuberculosis: Latency and reactivation
-
Flynn, J. L. & Chan, J. Tuberculosis: latency and reactivation. Infect. Immun. 69, 4195-4201 (2001).
-
(2001)
Infect. Immun.
, vol.69
, pp. 4195-4201
-
-
Flynn, J.L.1
Chan, J.2
-
3
-
-
0043142536
-
Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment
-
Schnappinger, D. et al. Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment. J. Exp. Med. 198, 693-704 (2003).
-
(2003)
J. Exp. Med.
, vol.198
, pp. 693-704
-
-
Schnappinger, D.1
-
4
-
-
66149105138
-
Cholesterol metabolism increases the metabolic pool of propionate in Mycobacterium tuberculosis
-
Yang, X., Nesbitt, N. M., Dubnau, E., Smith, I. & Sampson, N. S. Cholesterol metabolism increases the metabolic pool of propionate in Mycobacterium tuberculosis. Biochemistry 48, 3819-3821 (2009).
-
(2009)
Biochemistry
, vol.48
, pp. 3819-3821
-
-
Yang, X.1
Nesbitt, N.M.2
Dubnau, E.3
Smith, I.4
Sampson, N.S.5
-
5
-
-
68249141854
-
Role of cholesterol inMycobacteriumtuberculosis infection
-
Miner, M. D., Chang, J. C., Pandey, A. K., Sassetti, C. M. & Sherman, D. R. Role of cholesterol inMycobacteriumtuberculosis infection. Indian J. Exp. Biol. 47, 407-411 (2009).
-
(2009)
Indian J. Exp. Biol.
, vol.47
, pp. 407-411
-
-
Miner, M.D.1
Chang, J.C.2
Pandey, A.K.3
Sassetti, C.M.4
Sherman, D.R.5
-
6
-
-
67749095756
-
Igr genes and Mycobacterium tuberculosis cholesterol metabolism
-
Chang, J. C. et al. igr genes and Mycobacterium tuberculosis cholesterol metabolism. J. Bacteriol. 191, 5232-5239 (2009).
-
(2009)
J. Bacteriol.
, vol.191
, pp. 5232-5239
-
-
Chang, J.C.1
-
7
-
-
79959815079
-
Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages
-
Daniel, J., Maamar, H., Deb, C., Sirakova, T. D. & Kolattukudy, P. E. Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages. PLoS Pathog. 7, e1002093 (2011).
-
(2011)
PLoS Pathog.
, vol.7
-
-
Daniel, J.1
Maamar, H.2
Deb, C.3
Sirakova, T.D.4
Kolattukudy, P.E.5
-
8
-
-
67749095757
-
Triacylglycerol utilization is required for regrowth of in vitro hypoxic nonreplicating Mycobacterium bovis bacillus Calmette-Guerin
-
Low, K. L. et al. Triacylglycerol utilization is required for regrowth of in vitro hypoxic nonreplicating Mycobacterium bovis bacillus Calmette-Guerin. J. Bacteriol. 191, 5037-5043 (2009).
-
(2009)
J. Bacteriol.
, vol.191
, pp. 5037-5043
-
-
Low, K.L.1
-
9
-
-
0036322591
-
Mycobacterium and the coat of many lipids
-
Russell, D. G., Mwandumba, H. C. & Rhoades, E. E. Mycobacterium and the coat of many lipids. J. Cell Biol. 158, 421-426 (2002).
-
(2002)
J. Cell Biol.
, vol.158
, pp. 421-426
-
-
Russell, D.G.1
Mwandumba, H.C.2
Rhoades, E.E.3
-
10
-
-
34547633677
-
Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing
-
Robertson, G. et al. Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing. Nature Methods 4, 651-657 (2007).
-
(2007)
Nature Methods
, vol.4
, pp. 651-657
-
-
Robertson, G.1
-
11
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
Mikkelsen, T. S. et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448, 553-560 (2007).
-
(2007)
Nature
, vol.448
, pp. 553-560
-
-
Mikkelsen, T.S.1
-
12
-
-
34250159524
-
Genome-wide mapping of in vivo protein-DNA interactions
-
Johnson, D. S., Mortazavi, A., Myers, R. M. & Wold, B. Genome-wide mapping of in vivo protein-DNA interactions. Science 316, 1497-1502 (2007).
-
(2007)
Science
, vol.316
, pp. 1497-1502
-
-
Johnson, D.S.1
Mortazavi, A.2
Myers, R.M.3
Wold, B.4
-
13
-
-
19744383611
-
Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor
-
Ehrt, S. et al. Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor. Nucleic Acids Res. 33, e21 (2005).
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Ehrt, S.1
-
14
-
-
34347375413
-
Controlling gene expression in mycobacteria
-
Ehrt, S. & Schnappinger, D. Controlling gene expression in mycobacteria. Future Microbiol. 1, 177-184 (2006).
-
(2006)
Future Microbiol.
, vol.1
, pp. 177-184
-
-
Ehrt, S.1
Schnappinger, D.2
-
15
-
-
64549137584
-
Improved tetracycline repressors for gene silencing in mycobacteria
-
Klotzsche, M., Ehrt, S. & Schnappinger, D. Improved tetracycline repressors for gene silencing in mycobacteria. Nucleic Acids Res. 37, 1778-1788 (2009).
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 1778-1788
-
-
Klotzsche, M.1
Ehrt, S.2
Schnappinger, D.3
-
16
-
-
68949213578
-
Insights from genomic profiling of transcription factors
-
Farnham, P. J. Insights from genomic profiling of transcription factors. Nature Rev. Genet. 10, 605-616 (2009).
-
(2009)
Nature Rev. Genet.
, vol.10
, pp. 605-616
-
-
Farnham, P.J.1
-
17
-
-
79953044960
-
Genome-wide transcription factor binding: Beyond direct target regulation
-
MacQuarrie,K. L., Fong,A.P.,Morse,R.H.&Tapscott, S. J.Genome-wide transcription factor binding: beyond direct target regulation. Trends Genet. 27, 141-148 (2011).
-
(2011)
Trends Genet.
, vol.27
, pp. 141-148
-
-
MacQuarrie, K.L.1
Fong, A.P.2
Morse, R.H.3
Tapscott, S.J.4
-
18
-
-
84874886134
-
ChIP-Seq and the complexity of bacterial transcriptional regulation
-
Galagan, J., Lyubetskaya, A. & Gomes, A. ChIP-Seq and the complexity of bacterial transcriptional regulation. Curr. Top. Microbiol. Immunol. 363, 43-68 (2013).
-
(2013)
Curr. Top. Microbiol. Immunol.
, vol.363
, pp. 43-68
-
-
Galagan, J.1
Lyubetskaya, A.2
Gomes, A.3
-
19
-
-
80052535188
-
Comprehensive insights into Mycobacterium tuberculosis DevR (DosR) regulon activation switch
-
Chauhan, S., Sharma, D., Singh, A., Surolia, A.& Tyagi, J. S. Comprehensive insights into Mycobacterium tuberculosis DevR (DosR) regulon activation switch. Nucleic Acids Res. 39, 7400-7414 (2011).
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 7400-7414
-
-
Chauhan, S.1
Sharma, D.2
Singh, A.3
Surolia, A.4
Tyagi, J.S.5
-
20
-
-
79551548079
-
Determinants outside the DevR C-terminal domain are essential for cooperativity and robust activation of dormancy genes in Mycobacterium tuberculosis
-
Gautam, U. S., Chauhan,S.&Tyagi, J. S. Determinants outside the DevR C-terminal domain are essential for cooperativity and robust activation of dormancy genes in Mycobacterium tuberculosis. PLoS ONE 6, e16500 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Gautam, U.S.1
Chauhan, S.2
Tyagi, J.S.3
-
21
-
-
46249101936
-
Expression of the Mycobacterium tuberculosis acr-coregulated genes from the DevR (DosR) regulon is controlled by multiple levels of regulation
-
Vasudeva-Rao, H. M. & McDonough, K. A. Expression of the Mycobacterium tuberculosis acr-coregulated genes from the DevR (DosR) regulon is controlled by multiple levels of regulation. Infect. Immun. 76, 2478-2489 (2008).
-
(2008)
Infect. Immun.
, vol.76
, pp. 2478-2489
-
-
Vasudeva-Rao, H.M.1
McDonough, K.A.2
-
22
-
-
83655163675
-
Deciphering the transcriptional regulatory logic of amino acid metabolism
-
Cho, B. K., Federowicz, S., Park, Y. S., Zengler, K. & Palsson, B. O. Deciphering the transcriptional regulatory logic of amino acid metabolism. Nature Chem. Biol. 8, 65-71 (2012).
-
(2012)
Nature Chem. Biol.
, vol.8
, pp. 65-71
-
-
Cho, B.K.1
Federowicz, S.2
Park, Y.S.3
Zengler, K.4
Palsson, B.O.5
-
23
-
-
63149084649
-
The multifunctional histone-like protein Lsr2 protects mycobacteria against reactive oxygen intermediates
-
Colangeli, R. et al. The multifunctional histone-like protein Lsr2 protects mycobacteria against reactive oxygen intermediates. Proc.Natl Acad. Sci.USA106, 4414-4418 (2009).
-
(2009)
Proc. Natl Acad. Sci.USA
, vol.106
, pp. 4414-4418
-
-
Colangeli, R.1
-
24
-
-
77950419841
-
Lsr2 is a nucleoid-associated protein that targets AT-rich sequences and virulence genes in Mycobacteriumtuberculosis
-
Gordon, B. R. et al. Lsr2 is a nucleoid-associated protein that targets AT-rich sequences and virulence genes in Mycobacteriumtuberculosis. Proc. Natl Acad. Sci. USA 107, 5154-5159 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 5154-5159
-
-
Gordon, B.R.1
-
25
-
-
43049182981
-
The enduring hypoxic response of Mycobacterium tuberculosis
-
Rustad, T. R., Harrell, M. I., Liao, R.&Sherman, D. R. The enduring hypoxic response of Mycobacterium tuberculosis. PLoS ONE 3, e1502 (2008).
-
(2008)
PLoS ONE
, vol.3
-
-
Rustad, T.R.1
Harrell, M.I.2
Liao, R.3
Sherman, D.R.4
-
26
-
-
34447567336
-
A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis
-
Kendall, S. L. et al. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Mol. Microbiol. 65, 684-699 (2007).
-
(2007)
Mol. Microbiol.
, vol.65
, pp. 684-699
-
-
Kendall, S.L.1
-
27
-
-
73449085857
-
A thiolase of Mycobacterium tuberculosis is required for virulence and production of androstenedione and androstadienedione from cholesterol
-
Nesbitt, N. M. et al. A thiolase of Mycobacterium tuberculosis is required for virulence and production of androstenedione and androstadienedione from cholesterol. Infect. Immun. 78, 275-282 (2010).
-
(2010)
Infect. Immun.
, vol.78
, pp. 275-282
-
-
Nesbitt, N.M.1
-
28
-
-
84860467728
-
Characterization of a novel ArsR-like regulator encoded by Rv2034 in Mycobacterium tuberculosis
-
Gao, C. H., Yang, M. & He, Z. G. Characterization of a novel ArsR-like regulator encoded by Rv2034 in Mycobacterium tuberculosis. PLoS ONE 7, e36255 (2012).
-
(2012)
PLoS ONE
, vol.7
-
-
Gao, C.H.1
Yang, M.2
He, Z.G.3
-
29
-
-
55649113699
-
PhoP: A missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence
-
Gonzalo-Asensio, J. et al. PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence. PLoS ONE 3, e3496 (2008).
-
(2008)
PLoS ONE
, vol.3
-
-
Gonzalo-Asensio, J.1
-
30
-
-
33644985559
-
The virulence-associated two-component PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosis
-
Gonzalo Asensio, J. et al. The virulence-associated two-component PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosis. J. Biol. Chem. 281, 1313-1316 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 1313-1316
-
-
Gonzalo Asensio, J.1
-
31
-
-
54849428103
-
PhoP a key player in Mycobacterium tuberculosis virulence
-
Ryndak, M., Wang, S. & Smith, I. PhoP, a key player in Mycobacterium tuberculosis virulence. Trends Microbiol. 16, 528-534 (2008).
-
(2008)
Trends Microbiol.
, vol.16
, pp. 528-534
-
-
Ryndak, M.1
Wang, S.2
Smith, I.3
-
32
-
-
79955031171
-
AprABC: A Mycobacterium tuberculosis complex-specific locus that modulates pH-driven adaptation to the macrophage phagosome
-
Abramovitch, R. B.,Rohde, K. H., Hsu, F. F.&Russell, D. G. aprABC: a Mycobacterium tuberculosis complex-specific locus that modulates pH-driven adaptation to the macrophage phagosome. Mol. Microbiol. 80, 678-694 (2011).
-
(2011)
Mol. Microbiol
, vol.80
, pp. 678-694
-
-
Abramovitch, B.1
Rohde R, K.H.2
Hsu, F.F.3
Russell, D.G.4
-
33
-
-
70149116303
-
Mycobacteriumtuberculosis Whi B 3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response
-
Singh, A. et al. MycobacteriumtuberculosisWhiB3maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response. PLoS Pathog. 5, e1000545 (2009).
-
(2009)
PLoS Pathog.
, vol.5
-
-
Singh, A.1
-
34
-
-
33846521053
-
Reconstructing dynamic regulatory maps
-
Ernst, J., Vainas, O., Harbison, C. T., Simon, I. & Bar-Joseph, Z. Reconstructing dynamic regulatory maps. Mol. Syst. Biol. 3, 74 (2007).
-
(2007)
Mol. Syst. Biol.
, vol.3
, pp. 74
-
-
Ernst, J.1
Vainas, O.2
Harbison, C.T.3
Simon, I.4
Bar-Joseph, Z.5
-
35
-
-
43249101747
-
Cytological and transcript analyses reveal fat and lazy persisterlike bacilli in tuberculous sputum
-
Garton, N. J. et al. Cytological and transcript analyses reveal fat and lazy persisterlike bacilli in tuberculous sputum. PLoS Med. 5, e75 (2008).
-
(2008)
PLoS Med.
, vol.5
-
-
Garton, N.J.1
-
36
-
-
0038349268
-
Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis
-
Park, H. D. et al. Rv3133c/dosR is a transcription factor that mediates the hypoxic response of Mycobacterium tuberculosis. Mol. Microbiol. 48, 833-843 (2003).
-
(2003)
Mol. Microbiol.
, vol.48
, pp. 833-843
-
-
Park, H.D.1
-
37
-
-
79958058975
-
Metabolic regulation of mycobacterial growth and antibiotic sensitivity
-
Baek, S. H., Li, A. H. & Sassetti, C. M. Metabolic regulation of mycobacterial growth and antibiotic sensitivity. PLoS Biol. 9, e1001065 (2011).
-
(2011)
PLoS Biol.
, vol.9
-
-
Baek, S.H.1
Li, A.H.2
Sassetti, C.M.3
-
38
-
-
0033523971
-
Complex lipid determines tissuespecific replication of Mycobacteriumtuberculosis inmice
-
Cox, J. S., Chen, B., McNeil, M. & Jacobs, W. R. Jr. Complex lipid determines tissuespecific replicationofMycobacteriumtuberculosis inmice. Nature402,79-83(1999).
-
(1999)
Nature
, vol.402
, pp. 79-83
-
-
Cox, J.S.1
Chen, B.2
McNeil, M.3
Jacobs Jr., W.R.4
-
39
-
-
0000812428
-
Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature-tagged transposon mutagenesis
-
Camacho, L. R., Ensergueix, D., Perez, E., Gicquel, B. & Guilhot, C. Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature-tagged transposon mutagenesis. Mol. Microbiol. 34, 257-267 (1999).
-
(1999)
Mol. Microbiol.
, vol.34
, pp. 257-267
-
-
Camacho, L.R.1
Ensergueix, D.2
Perez, E.3
Gicquel, B.4
Guilhot, C.5
-
40
-
-
0038623770
-
MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence
-
Converse, S. E. et al.MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence. Proc. Natl Acad. Sci. USA 100, 6121-6126 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 6121-6126
-
-
Converse, S.E.1
-
41
-
-
2442686856
-
The role of MmpL8 in sulfatide biogenesis and virulence of Mycobacterium tuberculosis
-
Domenech, P. et al. The role of MmpL8 in sulfatide biogenesis and virulence of Mycobacterium tuberculosis. J. Biol. Chem. 279, 21257-21265 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21257-21265
-
-
Domenech, P.1
-
42
-
-
1342325735
-
Production of phthiocerol dimycocerosates protects Mycobacterium tuberculosis from the cidal activity of reactive nitrogen intermediates produced by macrophages and modulates the early immune response to infection
-
Rousseau, C. et al. Production of phthiocerol dimycocerosates protects Mycobacterium tuberculosis from the cidal activity of reactive nitrogen intermediates produced by macrophages and modulates the early immune response to infection. Cell. Microbiol. 6, 277-287 (2004).
-
(2004)
Cell. Microbiol.
, vol.6
, pp. 277-287
-
-
Rousseau, C.1
-
43
-
-
79959692020
-
Role of lipid components in formation and reactivation of Mycobacterium smegmatis "nonculturable" cells
-
Nazarova, E. V. et al. Role of lipid components in formation and reactivation of Mycobacterium smegmatis "nonculturable" cells. Biochemistry 76, 636-644 (2011).
-
(2011)
Biochemistry
, vol.76
, pp. 636-644
-
-
Nazarova, E.V.1
-
44
-
-
45149110879
-
Growth of Mycobacteriumtuberculosis biofilms containing free my colic acids and harbouring drug-tolerant bacteria
-
Ojha,A.K. et al.GrowthofMycobacteriumtuberculosis biofilmscontainingfreemycolic acids and harbouring drug-tolerant bacteria. Mol. Microbiol. 69, 164-174 (2008).
-
(2008)
Mol. Microbiol.
, vol.69
, pp. 164-174
-
-
Ojha, A.K.1
-
45
-
-
77952914135
-
Enzymatic hydrolysis of trehalose dimycolate releases free mycolic acids during mycobacterial growth in biofilms
-
Ojha, A. K., Trivelli, X., Guerardel, Y., Kremer, L. & Hatfull, G. F. Enzymatic hydrolysis of trehalose dimycolate releases free mycolic acids during mycobacterial growth in biofilms. J. Biol. Chem. 285, 17380-17389 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 17380-17389
-
-
Ojha, A.K.1
Trivelli, X.2
Guerardel, Y.3
Kremer, L.4
Hatfull, G.F.5
-
46
-
-
84860731440
-
Non-coding RNA and its potential role in Mycobacterium tuberculosis pathogenesis
-
Arnvig, K. & Young, D. Non-coding RNA and its potential role in Mycobacterium tuberculosis pathogenesis. RNA Biol. 9, 427-436 (2012).
-
(2012)
RNA Biol.
, vol.9
, pp. 427-436
-
-
Arnvig, K.1
Young, D.2
|