Lack of IL-10 alters inflammatory and immune responses during pulmonary Mycobacterium tuberculosis infection

Tuberculosis

Volumn 89, Issue 2, 2009, Pages 149-157

  Higgins, David M ^a   Sanchez Campillo, Joaquin ^a   Rosas Taraco, Adrian G ^a   Lee, Eric J ^a   Orme, Ian M ^a   Gonzalez Juarrero, Mercedes ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Cytokines; IL 10; Inflammation; Murine; Th1; Tuberculosis

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; CELL POPULATION; CELLULAR DISTRIBUTION; CELLULAR IMMUNITY; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GENE DISRUPTION; GENE EXPRESSION; GENE FUNCTION; IMMUNE RESPONSE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; TH1 CELL; TUBERCULOSIS; ANIMAL; BIOSYNTHESIS; DEFICIENCY; FLOW CYTOMETRY; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; ISOLATION AND PURIFICATION; KNOCKOUT MOUSE; LUNG; LUNG TUBERCULOSIS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBPOPULATION; METABOLISM; MICROBIOLOGY; PATHOLOGY; PROCEDURES;

ANIMALS; CYTOKINES; DISEASE PROGRESSION; FEMALE; FLOW CYTOMETRY; IMMUNE TOLERANCE; INTERLEUKIN-10; LUNG; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; MICE; MICE, KNOCKOUT; MYCOBACTERIUM TUBERCULOSIS; TH1 CELLS; TRANSFORMING GROWTH FACTOR BETA; TUBERCULOSIS, PULMONARY;

EID: 61649094923     PISSN: 14729792     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tube.2009.01.001     Document Type: Article

References (36)

1. WHO. Global tuberculosis control: surveillance, planning, financing. WHO report 2002 communical diseases (2002), World Health Organization, Geneva
2. WHO. Global MDR-TB and XDR-TB response plan 2007-2008. WHO report 2007 (2007), World Health Organization, Geneva
3. Orme I.M., and Cooper A.M. Cytokine/chemokine cascades in immunity to tuberculosis. Immunol Today 20 (1999) 307-312
4. Moore K.W., de Waal Malefyt R., Coffman R.L., and O'Garra A. Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol 19 (2001) 683-765
5. Orme I.M., Roberts A.D., Griffin J.P., and Abrams J.S. Cytokine secretion by CD4 T lymphocytes acquired in response to Mycobacterium tuberculosis infection. J Immunol 151 (1993) 518-525
6. Junqueira-Kipnis A.P., Kipnis A., Henao Tamayo M., Harton M., Gonzalez Juarrero M., Basaraba R.J., et al. Interleukin-10 production by lung macrophages in CBA xid mutant mice infected with Mycobacterium tuberculosis. Immunology 115 (2005) 246-252
7. Giacomini E., Iona E., Ferroni L., Miettinen M., Fattorini L., Orefici G., et al. Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response. J Immunol 166 (2001) 7033-7041
8. Redpath S., Ghazal P., and Gascoigne N.R. Hijacking and exploitation of IL-10 by intracellular pathogens. Trends Microbiol 9 (2001) 86-92
9. O'Garra A., Vieira P.L., Vieira P., and Goldfeld A.E. IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage. J Clin Invest 114 (2004) 1372-1378
10. Scott-Browne J.P., Shafiani S., Tucker-Heard G., Ishida-Tsubota K., Fontenot J.D., Rudensky A.Y., et al. Expansion and function of Foxp3-expressing T regulatory cells during tuberculosis. J Exp Med 204 (2007) 2159-2169
11. Ordway D., Henao-Tamayo M., Harton M., Palanisamy G., Troudt J., Shanley C., et al. The hypervirulent Mycobacterium tuberculosis strain HN878 induces a potent TH1 response followed by rapid down-regulation. J Immunol 179 (2007) 522-531
12. Turner J., Gonzalez-Juarrero M., Ellis D.L., Basaraba R.J., Kipnis A., Orme I.M., et al. In vivo IL-10 production reactivates chronic pulmonary tuberculosis in C57BL/6 mice. J Immunol 169 (2002) 6343-6351
13. erbon A., Juffermans N., Van Deventer S.J., Speelman P., Van Deutekom H., and Van Der Poll T. Serum concentrations of cytokines in patients with active tuberculosis (TB) and after treatment. Clin Exp Immunol 115 (1999) 110-113
14. Jacobs M., Brown N., Allie N., Gulert R., and Ryffel B. Increased resistance to mycobacterial infection in the absence of interleukin-10. Immunology 100 (2000) 494-501
15. Roque S., Nobrega C., Appelberg R., and Correia-Neves M. IL-10 underlies distinct susceptibility of BALB/c and C57BL/6 mice to Mycobacterium avium infection and influences efficacy of antibiotic therapy. J Immunol 178 (2007) 8028-8035
16. Beamer G.L., Flaherty D.K., Assogba B.D., Stromberg P., Gonzalez-Juarrero M., de Waal Malefyt R., et al. Interleukin-10 promotes Mycobacterium tuberculosis disease progression in CBA/J mice. J Immunol 181 (2008) 5545-5550
17. Murray P.J., and Young R.A. Increased antimycobacterial immunity in interleukin-10-deficient mice. Infect Immun 67 (1999) 3087-3095
18. North R.J. Mice incapable of making IL-4 or IL-10 display normal resistance to infection with Mycobacterium tuberculosis. Clin Exp Immunol 113 (1998) 55-58
19. Jung Y.J., Ryan L., LaCourse R., and North R.J. Increased interleukin-10 expression is not responsible for failure of T helper 1 immunity to resolve airborne Mycobacterium tuberculosis infection in mice. Immunology 109 (2003) 295-299
20. Kuhn R., Lohler J., Rennick D., Rajewsky K., and Muller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75 (1993) 263-274
21. Gonzalez-Juarrero M., Hattle J.M., Izzo A., Junqueira-Kipnis A.P., Shim T.S., Trapnell B.C., et al. Disruption of granulocyte macrophage-colony stimulating factor production in the lungs severely affects the ability of mice to control Mycobacterium tuberculosis infection. J Leukoc Biol 77 (2005) 914-922
22. Rhoades E.R., Frank A.A., and Orme I.M. Progression of chronic pulmonary tuberculosis in mice aerogenically infected with virulent Mycobacterium tuberculosis. Tuber Lung Dis 78 (1997) 57-66
23. North R.J., and Jung Y.J. Immunity to tuberculosis. Annu Rev Immunol 22 (2004) 599-623
24. Ordway D., Henao-Tamayo M., Orme I.M., and Gonzalez-Juarrero M. Foamy macrophages within lung granulomas of mice infected with Mycobacterium tuberculosis express molecules characteristic of dendritic cells and antiapoptotic markers of the TNF receptor-associated factor family. J Immunol 175 (2005) 3873-3881
25. Ordway D., Harton M., Henao-Tamayo M., Montoya R., Orme I.M., and Gonzalez-Juarrero M. Enhanced macrophage activity in granulomatous lesions of immune mice challenged with Mycobacterium tuberculosis. J Immunol 176 (2006) 4931-4939
26. Cooper A., Dalton D., Stewart T., Griffin J., Russell D., and Orme I. Disseminated tuberculosis in interferon gamma gene-disrupted mice. J Exp Med 178 (1993) 2243-2247 doi:10.1084/jem.178.6.2243
27. de Jong R., Altare F., Haagen I.A., Elferink D.G., Boer T., van Breda Vriesman P.J., et al. Severe mycobacterial and salmonella infections in interleukin-12 receptor-deficient patients. Science 280 (1998) 1435-1438
28. Jouanguy E., Altare F., Lamhamedi S., Revy P., Emile J.F., Newport M., et al. Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guerin infection. N Engl J Med 335 (1996) 1956-1961
29. Demangel C., Bertolino P., and Britton W.J. Autocrine IL-10 impairs dendritic cell (DC)-derived immune responses to mycobacterial infection by suppressing DC trafficking to draining lymph nodes and local IL-12 production. Eur J Immunol 32 (2002) 994-1002
30. Li M.O., Wan Y.Y., Sanjabi S., Robertson A.K., and Flavell R.A. Transforming growth factor-beta regulation of immune responses. Annu Rev Immunol 24 (2006) 99-146
31. Takaki H., Minoda Y., Koga K., Takaesu G., Yoshimura A., and Kobayashi T. TGF-beta1 suppresses IFN-gamma-induced NO production in macrophages by suppressing STAT1 activation and accelerating iNOS protein degradation. Genes Cells 11 (2006) 871-882
32. Hernandez-Pando R., Orozco-Esteves H., Maldonado H.A., Aguilar-Leon D., Vilchis-Landeros M.M., Mata-Espinosa D.A., et al. A combination of a transforming growth factor-beta antagonist and an inhibitor of cyclooxygenase is an effective treatment for murine pulmonary tuberculosis. Clin Exp Immunol 144 (2006) 264-272
33. Moiton M.P., Richez C., Dumoulin C., Mehsen N., Dehais J., and Schaeverbeke T. Role of anti-tumour necrosis factor-alpha therapeutic agents in the emergence of infections. Clin Microbiol Infect 12 (2006) 1151-1153
34. Glynn J.R., Crampin A.C., Yates M.D., Traore H., Mwaungulu F.D., Ngwira B.M., et al. The importance of recent infection with Mycobacterium tuberculosis in an area with high HIV prevalence: a long-term molecular epidemiological study in Northern Malawi. J Infect Dis 192 (2005) 480-487
35. Eum S.Y., Jeon B.Y., Min J.H., Kim S.C., Cho S., Park S.K., et al. Tumor necrosis factor-alpha and interleukin-10 in whole blood is associated with disease progression in pulmonary multidrug-resistant tuberculosis patients. Respiration 76 (2008) 331-337
36. Hussain R., Talat N., Shahid F., and Dawood G. Longitudinal tracking of cytokines after acute exposure to tuberculosis: association of distinct cytokine patterns with protection and disease development. Clin Vaccine Immunol 14 (2007) 1578-1586