-
1
-
-
33644991496
-
Global epidemiology of tuberculosis
-
Dye C. 2006. Global epidemiology of tuberculosis. Lancet 367:938-940.
-
(2006)
Lancet
, vol.367
, pp. 938-940
-
-
Dye, C.1
-
2
-
-
77952545901
-
Tuberculosis drug development: Progress, challenges, and the road ahead
-
Ginsberg AM. 2010. Tuberculosis drug development: progress, challenges, and the road ahead. Tuberculosis (Edinb.) 90:162-167.
-
(2010)
Tuberculosis (Edinb.)
, vol.90
, pp. 162-167
-
-
Ginsberg, A.M.1
-
3
-
-
39049161926
-
Preclinical testing of new drugs for tuberculosis: Current challenges
-
Lenaerts AJ, Degroote MA, Orme IM. 2008. Preclinical testing of new drugs for tuberculosis: current challenges. Trends Microbiol. 16:48-54.
-
(2008)
Trends Microbiol
, vol.16
, pp. 48-54
-
-
Lenaerts, A.J.1
Degroote, M.A.2
Orme, I.M.3
-
4
-
-
78650642282
-
PA-824 exhibits time-dependent activity in a murine model of tuberculosis
-
Ahmad Z, Peloquin CA, Singh RP, Derendorf H, Tyagi S, Ginsberg A, Grosset JH, Nuermberger EL. 2011. PA-824 exhibits time-dependent activity in a murine model of tuberculosis. Antimicrob. Agents Chemother. 55:239-245.
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 239-245
-
-
Ahmad, Z.1
Peloquin, C.A.2
Singh, R.P.3
Derendorf, H.4
Tyagi, S.5
Ginsberg, A.6
Grosset, J.H.7
Nuermberger, E.L.8
-
5
-
-
53549104456
-
Using animal models to develop new treatments for tuberculosis
-
Nuermberger E. 2008. Using animal models to develop new treatments for tuberculosis. Semin. Respir. Crit. Care Med. 29:542-551.
-
(2008)
Semin. Respir. Crit. Care Med.
, vol.29
, pp. 542-551
-
-
Nuermberger, E.1
-
6
-
-
17144386211
-
Ipr1 gene mediates innate immunity to tuberculosis
-
Pan H, Yan BS, Rojas M, Shebzukhov YV, Zhou H, Kobzik L, Higgins DE, Daly MJ, Bloom BR, Kramnik I. 2005. Ipr1 gene mediates innate immunity to tuberculosis. Nature 434:767-772.
-
(2005)
Nature
, vol.434
, pp. 767-772
-
-
Pan, H.1
Yan, B.S.2
Rojas, M.3
Shebzukhov, Y.V.4
Zhou, H.5
Kobzik, L.6
Higgins, D.E.7
Daly, M.J.8
Bloom, B.R.9
Kramnik, I.10
-
7
-
-
84856301870
-
Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions
-
Harper J, Skerry C, Davis SL, Tasneen R, Weir M, Kramnik I, Bishai WR, Pomper MG, Nuermberger EL, Jain SK. 2012. Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions. J. Infect. Dis. 205:595-602.
-
(2012)
J. Infect. Dis.
, vol.205
, pp. 595-602
-
-
Harper, J.1
Skerry, C.2
Davis, S.L.3
Tasneen, R.4
Weir, M.5
Kramnik, I.6
Bishai, W.R.7
Pomper, M.G.8
Nuermberger, E.L.9
Jain, S.K.10
-
8
-
-
77952357833
-
New initiative speeds tuberculosis drug development: Novel drug regimens become possible in years, not decades
-
Spigelman M, Woosley R, Gheuens J. 2010. New initiative speeds tuberculosis drug development: novel drug regimens become possible in years, not decades. Int. J. Tuberc. Lung Dis. 14:663-664.
-
(2010)
Int. J. Tuberc. Lung Dis.
, vol.14
, pp. 663-664
-
-
Spigelman, M.1
Woosley, R.2
Gheuens, J.3
-
9
-
-
79952336855
-
Comparative studies evaluating mouse models used for efficacy testing of experimental drugs against Mycobacterium tuberculosis
-
De Groote MA, Gilliland JC, Wells CL, Brooks EJ, Woolhiser LK, Gruppo V, Peloquin CA, Orme IM, Lenaerts AJ. 2011. Comparative studies evaluating mouse models used for efficacy testing of experimental drugs against Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 55:1237-1247.
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 1237-1247
-
-
De Groote, M.A.1
Gilliland, J.C.2
Wells, C.L.3
Brooks, E.J.4
Woolhiser, L.K.5
Gruppo, V.6
Peloquin, C.A.7
Orme, I.M.8
Lenaerts, A.J.9
-
10
-
-
0037662753
-
Pharmacokinetics-pharmacodynamics of rifampin in an aerosol infection model of tuberculosis
-
Jayaram R, Gaonkar S, Kaur P, Suresh BL, Mahesh BN, Jayashree R, Nandi V, Bharat S, Shandil RK, Kantharaj E, Balasubramanian V. 2003. Pharmacokinetics-pharmacodynamics of rifampin in an aerosol infection model of tuberculosis. Antimicrob. Agents Chemother. 47:2118-2124.
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 2118-2124
-
-
Jayaram, R.1
Gaonkar, S.2
Kaur, P.3
Suresh, B.L.4
Mahesh, B.N.5
Jayashree, R.6
Nandi, V.7
Bharat, S.8
Shandil, R.K.9
Kantharaj, E.10
Balasubramanian, V.11
-
11
-
-
54049098833
-
Enhanced bactericidal activity of rifampin and/or pyrazinamide when combined with PA-824 in a murine model of tuberculosis
-
Tasneen R, Tyagi S, Williams K, Grosset J, Nuermberger E. 2008. Enhanced bactericidal activity of rifampin and/or pyrazinamide when combined with PA-824 in a murine model of tuberculosis. Antimicrob. Agents Chemother. 52:3664-3668.
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 3664-3668
-
-
Tasneen, R.1
Tyagi, S.2
Williams, K.3
Grosset, J.4
Nuermberger, E.5
-
12
-
-
81555221113
-
Sterilizing activity of novel TMC207-and PA-824-containing regimens in a murine model of tuberculosis
-
Tasneen R, Li SY, Peloquin CA, Taylor D, Williams KN, Andries K, Mdluli KE, Nuermberger EL. 2011. Sterilizing activity of novel TMC207-and PA-824-containing regimens in a murine model of tuberculosis. Antimicrob. Agents Chemother. 55:5485-5492.
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 5485-5492
-
-
Tasneen, R.1
Li, S.Y.2
Peloquin, C.A.3
Taylor, D.4
Williams, K.N.5
Andries, K.6
Mdluli, K.E.7
Nuermberger, E.L.8
-
13
-
-
84858767373
-
Quantitativeandsystemspharmacologyinthepost-genomicera:newapproaches to discovering drugsandunderstanding therapeutic mechanisms
-
AnNIHWhite Paper by the -October 2011. National Institutes of Health, Bethesda, MD
-
Sorger PK, Allerheiligen SRB, Abernethy DR, Altman RB, Brouwer KLR, Califano A, D'Argenio DZ, Iyengar R, Jusko WJ, Lalonde R, Lauffenburger DA, Shoichet B, Stevens JL, Subramaniam S, Van der Graaf P, Vicini P. 2011. Quantitativeandsystemspharmacologyinthepost-genomicera:newapproaches to discovering drugsandunderstanding therapeutic mechanisms.AnNIHWhite Paper by the QSP Workshop Group-October 2011. National Institutes of Health, Bethesda, MD. http://www.nigms.nih.gov/NR/rdonlyres/8ECB1F7C-BE3B-431F-89E6-A43411811AB1/0/ SystemsPharmaWPSorger2011.pdf.
-
(2011)
QSP Workshop Group
-
-
Sorger, P.K.1
Allerheiligen, S.R.B.2
Abernethy, D.R.3
Altman, R.B.4
Brouwer, K.L.R.5
Califano, A.6
D'Argenio, D.Z.7
Iyengar, R.8
Jusko, W.J.9
Lalonde, R.10
Lauffenburger, D.A.11
Shoichet, B.12
Stevens, J.L.13
Subramaniam, S.14
Van Der Graaf, P.15
Vicini, P.16
-
14
-
-
75149151920
-
Tuberculosis research: Going forward with a powerful "translational systems biology" approach
-
Day J, Schlesinger LS, Friedman A. 2010. Tuberculosis research: going forward with a powerful "translational systems biology" approach. Tuberculosis (Edinb.) 90:7-8.
-
(2010)
Tuberculosis (Edinb.)
, vol.90
, pp. 7-8
-
-
Day, J.1
Schlesinger, L.S.2
Friedman, A.3
-
16
-
-
40649092775
-
A model on the influence of age on immunity to infection with Mycobacterium tuberculosis
-
Friedman A, Turner J, Szomolay B. 2008. A model on the influence of age on immunity to infection with Mycobacterium tuberculosis. Exp. Gerontol. 43:275-285.
-
(2008)
Exp. Gerontol.
, vol.43
, pp. 275-285
-
-
Friedman, A.1
Turner, J.2
Szomolay, B.3
-
17
-
-
79957790326
-
Mathematical modeling of pulmonary tuberculosis therapy: Insights from a prototype model with rifampin
-
Goutelle S, Bourguignon L, Jelliffe RW, Conte JE, Jr, Maire P. 2011. Mathematical modeling of pulmonary tuberculosis therapy: insights from a prototype model with rifampin. J. Theor. Biol. 282:80-92.
-
(2011)
J. Theor. Biol.
, vol.282
, pp. 80-92
-
-
Goutelle, S.1
Bourguignon, L.2
Jelliffe, R.W.3
Conte Jr., J.E.4
Maire, P.5
-
18
-
-
33845580084
-
Mathematical modeling of chemotherapy of human TB infection
-
Magombedze G, Garira W, Mwenje E. 2006. Mathematical modeling of chemotherapy of human TB infection. J. Biol. Syst. 14:509-553.
-
(2006)
J. Biol. Syst.
, vol.14
, pp. 509-553
-
-
Magombedze, G.1
Garira, W.2
Mwenje, E.3
-
19
-
-
0037441632
-
Treatment of tuberculosis
-
American Thoracic Society Centers for Disease Control and Prevention, the Infectious Diseases Society. American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America
-
Blumberg HM, Burman WJ, Chaisson RE, Daley CL, Etkind SC, Friedman LN, Fujiwara P, Grzemska M, Hopewell PC, Iseman MD, Jasmer RM, Koppaka V, Menzies RI, O'Brien RJ, Reves RR, Reichman LB, Simone PM, Starke JR, Vernon AA, American Thoracic Society, Centers for Disease Control and Prevention, the Infectious Diseases Society. 2003. American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America: treatment of tuberculosis. Am. J. Respir. Crit. Care Med. 167:603-662.
-
(2003)
Am. J. Respir. Crit. Care Med.
, vol.167
, pp. 603-662
-
-
Blumberg, H.M.1
Burman, W.J.2
Chaisson, R.E.3
Daley, C.L.4
Etkind, S.C.5
Friedman, L.N.6
Fujiwara, P.7
Grzemska, M.8
Hopewell, P.C.9
Iseman, M.D.10
Jasmer, R.M.11
Koppaka, V.12
Menzies, R.I.13
O'Brien, R.J.14
Reves, R.R.15
Reichman, L.B.16
Simone, P.M.17
Starke, J.R.18
Vernon, A.A.19
-
20
-
-
77951092627
-
New drugs and new regimens for the treatment of tuberculosis: Review of the drug development pipeline and implications for national programmes
-
Lienhardt C, Vernon A, Raviglione MC. 2010. New drugs and new regimens for the treatment of tuberculosis: review of the drug development pipeline and implications for national programmes. Curr. Opin. Pulm. Med. 16:186-193.
-
(2010)
Curr. Opin. Pulm. Med.
, vol.16
, pp. 186-193
-
-
Lienhardt, C.1
Vernon, A.2
Raviglione, M.C.3
-
21
-
-
50349094162
-
Experimental tuberculosis: The role of comparative pathology in the discovery of improved tuberculosis treatment strategies
-
Basaraba RJ. 2008. Experimental tuberculosis: the role of comparative pathology in the discovery of improved tuberculosis treatment strategies. Tuberculosis (Edinb.) 88(Suppl 1):S35-S47.
-
(2008)
Tuberculosis (Edinb.)
, vol.88
, Issue.SUPPL. 1
-
-
Basaraba, R.J.1
-
22
-
-
0002381794
-
MCSim: A simulation program
-
Bois F, Maszle D. 1997. MCSim: a simulation program. J. Stat. Softw. 2:1-60.
-
(1997)
J. Stat. Softw.
, vol.2
, pp. 1-60
-
-
Bois, F.1
Maszle, D.2
-
23
-
-
0001811061
-
ODEPACK, a systemized collection of ODE solvers
-
Stepleman RS, Carver M, Peskin R, Ames WF, Vichnevetsky R (ed), North-Holland Pub. Co., Amsterdam, Netherlands
-
Hindmarsh AC. 1983. ODEPACK, a systemized collection of ODE solvers, p 55-64. In Stepleman RS, Carver M, Peskin R, Ames WF, Vichnevetsky R (ed), Scientific computing, IMACS transactions of scientific computation, vol 1. North-Holland Pub. Co., Amsterdam, Netherlands.
-
(1983)
Scientific Computing, IMACS Transactions of Scientific Computation
, vol.1
, pp. 55-64
-
-
Hindmarsh, A.C.1
-
24
-
-
0038312668
-
Adaptive rejection metropolis sampling within Gibbs sampling
-
Gilks WR, Best NG, Tan KKC. 1995. Adaptive rejection metropolis sampling within Gibbs sampling. Appl. Stat. 44:455-472.
-
(1995)
Appl. Stat.
, vol.44
, pp. 455-472
-
-
Gilks, W.R.1
Best, N.G.2
Tan, K.K.C.3
-
25
-
-
84863304598
-
-
R Foundation for Statistical Computing, Vienna, Austria
-
R Development Core Team. 2012. R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. http://www.Rproject.org.
-
(2012)
R: A Language and Environment for Statistical Computing
-
-
-
26
-
-
0015179896
-
Rifampicin, a general review
-
Binda G, Domenichini E, Gottardi A, Orlandi B, Ortelli E, Pacini B, Fowst G. 1971. Rifampicin, a general review. Arzneimittelforschung 21: 1907-1977.
-
(1971)
Arzneimittelforschung
, vol.21
, pp. 1907-1977
-
-
Binda, G.1
Domenichini, E.2
Gottardi, A.3
Orlandi, B.4
Ortelli, E.5
Pacini, B.6
Fowst, G.7
-
27
-
-
0033971447
-
Pharmacokinetics and tissue distribution of rifametane, a new 3-azinomethyl-rifamycin derivative, in several animal species
-
Bruzzese T, Rimaroli C, Bonabello A, Mozzi G, Ajay S, Cooverj ND. 2000. Pharmacokinetics and tissue distribution of rifametane, a new 3-azinomethyl-rifamycin derivative, in several animal species. Arzneimittelforschung 50:60-71.
-
(2000)
Arzneimittelforschung
, vol.50
, pp. 60-71
-
-
Bruzzese, T.1
Rimaroli, C.2
Bonabello, A.3
Mozzi, G.4
Ajay, S.5
Cooverj, N.D.6
-
28
-
-
0024553339
-
Therapeutic efficacy of liposome-entrapped rifampin against Mycobacterium avium complex infection induced in mice
-
Saito H, Tomioka H. 1989. Therapeutic efficacy of liposome-entrapped rifampin against Mycobacterium avium complex infection induced in mice. Antimicrob. Agents Chemother. 33:429-433.
-
(1989)
Antimicrob. Agents Chemother.
, vol.33
, pp. 429-433
-
-
Saito, H.1
Tomioka, H.2
-
29
-
-
33748920414
-
Quantitative analysis of rifampin for evaluating pharmacokinetics and tissue distribution in mice
-
Yang X, Matheny CJ, White NR, Pollack GM. 2003. Quantitative analysis of rifampin for evaluating pharmacokinetics and tissue distribution in mice. Pharm. Sci. 5:4.
-
(2003)
Pharm. Sci.
, vol.5
, pp. 4
-
-
Yang, X.1
Matheny, C.J.2
White, N.R.3
Pollack, G.M.4
-
30
-
-
79851489099
-
Activities of rifampin, rifapentine and clarithromycin alone and in combination against Mycobacterium ulcerans disease in mice
-
doi:10.1371/journal.pntd.0000933
-
Almeida D, Converse PJ, Ahmad Z, Dooley KE, Nuermberger EL, Grosset JH. 2011. Activities of rifampin, rifapentine and clarithromycin alone and in combination against Mycobacterium ulcerans disease in mice. PLoS Negl. Trop. Dis. 5:e933. doi:10.1371/journal.pntd.0000933.
-
(2011)
PLoS Negl. Trop. Dis.
, vol.5
-
-
Almeida, D.1
Converse, P.J.2
Ahmad, Z.3
Dooley, K.E.4
Nuermberger, E.L.5
Grosset, J.H.6
-
32
-
-
0027744137
-
Effectiveness of rifampin, rifabutin, and rifapentine for preventive therapy of tuberculosis in mice
-
Ji B, Truffot-Pernot C, Lacroix C, Raviglione MC, O'Brien RJ, Olliaro P, Roscigno G, Grosset J. 1993. Effectiveness of rifampin, rifabutin, and rifapentine for preventive therapy of tuberculosis in mice. Am. Rev. Respir. Dis. 148:1541-1546.
-
(1993)
Am. Rev. Respir. Dis.
, vol.148
, pp. 1541-1546
-
-
Ji, B.1
Truffot-Pernot, C.2
Lacroix, C.3
Raviglione, M.C.4
O'Brien, R.J.5
Olliaro, P.6
Roscigno, G.7
Grosset, J.8
-
33
-
-
79953004596
-
Pharmacokinetic-pharmacodynamic modeling of rifampicinmediated Cyp3a11 induction in steroid and xenobiotic X receptor humanized mice
-
Raybon JJ, Pray D, Morgan DG, Zoeckler M, Zheng M, Sinz M, Kim S. 2011. Pharmacokinetic-pharmacodynamic modeling of rifampicinmediated Cyp3a11 induction in steroid and xenobiotic X receptor humanized mice. J. Pharmacol. Exp. Ther. 337:75-82.
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.337
, pp. 75-82
-
-
Raybon, J.J.1
Pray, D.2
Morgan, D.G.3
Zoeckler, M.4
Zheng, M.5
Sinz, M.6
Kim, S.7
-
34
-
-
38049038389
-
Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model
-
doi:10.1371/journal.pmed.0040344
-
Rosenthal IM, Zhang M, Williams KN, Peloquin CA, Tyagi S, Vernon AA, Bishai WR, Chaisson RE, Grosset JH, Nuermberger EL. 2007. Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model. PLoS Med. 4:e344. doi:10.1371/journal.pmed.0040344.
-
(2007)
PLoS Med.
, vol.4
-
-
Rosenthal, I.M.1
Zhang, M.2
Williams, K.N.3
Peloquin, C.A.4
Tyagi, S.5
Vernon, A.A.6
Bishai, W.R.7
Chaisson, R.E.8
Grosset, J.H.9
Nuermberger, E.L.10
-
35
-
-
84864383796
-
Dose-ranging comparison of rifampin and rifapentine in two pathologically distinct murine models of tuberculosis
-
Rosenthal IM, Tasneen R, Peloquin CA, Zhang M, Almeida D, Mdluli KE, Karakousis PC, Grosset JH, Nuermberger EL. 2012. Dose-ranging comparison of rifampin and rifapentine in two pathologically distinct murine models of tuberculosis. Antimicrob. Agents Chemother. 56:4331-4340.
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 4331-4340
-
-
Rosenthal, I.M.1
Tasneen, R.2
Peloquin, C.A.3
Zhang, M.4
Almeida, D.5
Mdluli, K.E.6
Karakousis, P.C.7
Grosset, J.H.8
Nuermberger, E.L.9
-
36
-
-
0034972610
-
Comparative pharmacokinetics and pharmacodynamics of the rifamycin antibacterials
-
Burman WJ, Gallicano K, Peloquin C. 2001. Comparative pharmacokinetics and pharmacodynamics of the rifamycin antibacterials. Clin. Pharmacokinet. 40:327-341.
-
(2001)
Clin. Pharmacokinet.
, vol.40
, pp. 327-341
-
-
Burman, W.J.1
Gallicano, K.2
Peloquin, C.3
-
37
-
-
0020326051
-
Rifampin blood and tissue levels in patients undergoing cardiac valve surgery
-
Archer GL, Armstrong BC, Kline BJ. 1982. Rifampin blood and tissue levels in patients undergoing cardiac valve surgery. Antimicrob. Agents Chemother. 21:800-803.
-
(1982)
Antimicrob. Agents Chemother.
, vol.21
, pp. 800-803
-
-
Archer, G.L.1
Armstrong, B.C.2
Kline, B.J.3
-
38
-
-
0019835548
-
Metabolism and pharmacokinetics of the antibiotic rifampin
-
Kenny MT, Strates B. 1981. Metabolism and pharmacokinetics of the antibiotic rifampin. Drug Metab. Rev. 12:159-218.
-
(1981)
Drug Metab. Rev.
, vol.12
, pp. 159-218
-
-
Kenny, M.T.1
Strates, B.2
-
39
-
-
0025759859
-
Penetration into tissues of various drugs active against gram-positive bacteria
-
Kropec A, Daschner FD. 1991. Penetration into tissues of various drugs active against gram-positive bacteria. J. Antimicrob. Chemother. 27(Suppl B):9-15.
-
(1991)
J. Antimicrob. Chemother.
, vol.27
, Issue.SUPPL. B
, pp. 9-15
-
-
Kropec, A.1
Daschner, F.D.2
-
40
-
-
0022347031
-
Pharmacokinetics of oral and intravenous rifampicin during chronic administration
-
Loos U, Musch E, Jensen JC, Mikus G, Schwabe HK, Eichelbaum M. 1985. Pharmacokinetics of oral and intravenous rifampicin during chronic administration. Klin. Wochenschr. 63:1205-1211.
-
(1985)
Klin. Wochenschr.
, vol.63
, pp. 1205-1211
-
-
Loos, U.1
Musch, E.2
Jensen, J.C.3
Mikus, G.4
Schwabe, H.K.5
Eichelbaum, M.6
-
42
-
-
33646124969
-
A novel strategy for physiologically based predictions of human pharmacokinetics
-
Jones HM, Parrott N, Jorga K, Lave T. 2006. A novel strategy for physiologically based predictions of human pharmacokinetics. Clin. Pharmacokinet. 45:511-542.
-
(2006)
Clin. Pharmacokinet.
, vol.45
, pp. 511-542
-
-
Jones, H.M.1
Parrott, N.2
Jorga, K.3
Lave, T.4
-
43
-
-
0141619296
-
Physiologically based pharmacokinetic (PBPK) modeling of disposition of epiroprim in humans
-
Luttringer O, Theil FP, Poulin P, Schmitt-Hoffmann AH, Guentert TW, Lave T. 2003. Physiologically based pharmacokinetic (PBPK) modeling of disposition of epiroprim in humans. J. Pharm. Sci. 92:1990-2007.
-
(2003)
J. Pharm. Sci.
, vol.92
, pp. 1990-2007
-
-
Luttringer, O.1
Theil, F.P.2
Poulin, P.3
Schmitt-Hoffmann, A.H.4
Guentert, T.W.5
Lave, T.6
-
44
-
-
0033937301
-
Statistical analysis of Clewell et al. PBPK model of trichloroethylene kinetics
-
Bois FY. 2000. Statistical analysis of Clewell et al. PBPK model of trichloroethylene kinetics. Environ. Health Perspect. 108(Suppl 2):307-316.
-
(2000)
Environ. Health Perspect.
, vol.108
, Issue.SUPPL. 2
, pp. 307-316
-
-
Bois, F.Y.1
-
45
-
-
0030932272
-
A general model for the origin of allometric scaling laws in biology
-
West GB, Brown JH, Enquist BJ. 1997. A general model for the origin of allometric scaling laws in biology. Science 276:122-126.
-
(1997)
Science
, vol.276
, pp. 122-126
-
-
West, G.B.1
Brown, J.H.2
Enquist, B.J.3
-
46
-
-
37549042390
-
Development and specification of physiologically based pharmacokinetic models for use in risk assessment
-
Clewell RA, Clewell HJ, III. 2008. Development and specification of physiologically based pharmacokinetic models for use in risk assessment. Regul. Toxicol. Pharmacol. 50:129-143.
-
(2008)
Regul. Toxicol. Pharmacol.
, vol.50
, pp. 129-143
-
-
Clewell, R.A.1
Clewell III, H.J.2
-
47
-
-
84856170852
-
Age-specific absolute and relative organ weight distributions for B6C3F1 mice
-
Marino DJ. 2012. Age-specific absolute and relative organ weight distributions for B6C3F1 mice. J. Toxicol. Environ. Health A 75:76-99.
-
(2012)
J. Toxicol. Environ. Health A
, vol.75
, pp. 76-99
-
-
Marino, D.J.1
-
48
-
-
77957176853
-
Variability of safe dose estimates when using complicated models of the carcinogenic process. A case study: Methylene chloride
-
Portier CJ, Kaplan NL. 1989. Variability of safe dose estimates when using complicated models of the carcinogenic process. A case study: methylene chloride. Fundam. Appl. Toxicol. 13:533-544.
-
(1989)
Fundam. Appl. Toxicol.
, vol.13
, pp. 533-544
-
-
Portier, C.J.1
Kaplan, N.L.2
-
49
-
-
16044365170
-
PBPK modeling/Monte Carlo simulation of methylene chloride kinetic changes in mice in relation to age and acute, subchronic, and chronic inhalation exposure
-
Thomas RS, Yang RS, Morgan DG, Moorman MP, Kermani HR, Sloane RA, O'Connor RW, Adkins B, Jr, Gargas ML, Andersen ME. 1996. PBPK modeling/Monte Carlo simulation of methylene chloride kinetic changes in mice in relation to age and acute, subchronic, and chronic inhalation exposure. Environ. Health Perspect. 104:858-865.
-
(1996)
Environ. Health Perspect.
, vol.104
, pp. 858-865
-
-
Thomas, R.S.1
Yang, R.S.2
Morgan, D.G.3
Moorman, M.P.4
Kermani, H.R.5
Sloane, R.A.6
O'Connor, R.W.7
Adkins Jr., B.8
Gargas, M.L.9
Andersen, M.E.10
-
52
-
-
0030806348
-
Physiological parameter values for physiologically based pharmacokinetic models
-
Brown RP, Delp MD, Lindstedt SL, Rhomberg LR, Beliles RP. 1997. Physiological parameter values for physiologically based pharmacokinetic models. Toxicol. Ind. Health 13:407-484.
-
(1997)
Toxicol. Ind. Health
, vol.13
, pp. 407-484
-
-
Brown, R.P.1
Delp, M.D.2
Lindstedt, S.L.3
Rhomberg, L.R.4
Beliles, R.P.5
-
55
-
-
82755162819
-
A mechanistic modeling framework for predicting metabolic interactions in complex mixtures
-
Cheng S, Bois FY. 2011. A mechanistic modeling framework for predicting metabolic interactions in complex mixtures. Environ. Health Perspect. 119:1712-1718.
-
(2011)
Environ. Health Perspect.
, vol.119
, pp. 1712-1718
-
-
Cheng, S.1
Bois, F.Y.2
-
57
-
-
8144221956
-
Chemical mixture toxicology: From descriptive to mechanistic, and going on to in silico toxicology
-
Yang RS, El-Masri HA, Thomas RS, Dobrev ID, Dennison JE, Jr, Bae DS, Campain JA, Liao KH, Reisfeld B, Andersen ME, Mumtaz M. 2004. Chemical mixture toxicology: from descriptive to mechanistic, and going on to in silico toxicology. Environ. Toxicol. Pharmacol. 18:65-81.
-
(2004)
Environ. Toxicol. Pharmacol.
, vol.18
, pp. 65-81
-
-
Yang, R.S.1
El-Masri, H.A.2
Thomas, R.S.3
Dobrev, I.D.4
Dennison Jr., J.E.5
Bae, D.S.6
Campain, J.A.7
Liao, K.H.8
Reisfeld, B.9
Andersen, M.E.10
Mumtaz, M.11
-
58
-
-
65349179649
-
Defining the role of macrophages in local moxifloxacin tissue concentrations using biopsy data and whole-body physiologically based pharmacokinetic modelling
-
Edginton AN, Ahr G, Willmann S, Stass H. 2009. Defining the role of macrophages in local moxifloxacin tissue concentrations using biopsy data and whole-body physiologically based pharmacokinetic modelling. Clin. Pharmacokinet. 48:181-187.
-
(2009)
Clin. Pharmacokinet.
, vol.48
, pp. 181-187
-
-
Edginton, A.N.1
Ahr, G.2
Willmann, S.3
Stass, H.4
-
59
-
-
84856077172
-
A physiologically based pharmacokinetic model for capreomycin
-
Reisfeld B, Metzler CP, Lyons MA, Mayeno AN, Brooks EJ, Degroote MA. 2012. A physiologically based pharmacokinetic model for capreomycin. Antimicrob. Agents Chemother. 56:926-934.
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 926-934
-
-
Reisfeld, B.1
Metzler, C.P.2
Lyons, M.A.3
Mayeno, A.N.4
Brooks, E.J.5
Degroote, M.A.6
-
60
-
-
84890762143
-
-
John Wiley & Sons, Inc., Hoboken, NJ
-
Reddy M, Yang RS, Andersen ME, Clewel HJ (ed). 2005. Physiologically based pharmacokinetic modeling: science and applications. John Wiley & Sons, Inc., Hoboken, NJ.
-
(2005)
Physiologically Based Pharmacokinetic Modeling: Science and Applications
-
-
Reddy, M.1
Yang, R.S.2
Andersen, M.E.3
Clewel, H.J.4
-
61
-
-
0033292078
-
Physiologically based pharmacokinetics of cyclosporine A: Reevaluation of dose-nonlinear kinetics in rats
-
Tanaka C, Kawai R, Rowland M. 1999. Physiologically based pharmacokinetics of cyclosporine A: reevaluation of dose-nonlinear kinetics in rats. J. Pharmacokinet. Biopharm. 27:597-623.
-
(1999)
J. Pharmacokinet. Biopharm.
, vol.27
, pp. 597-623
-
-
Tanaka, C.1
Kawai, R.2
Rowland, M.3
-
62
-
-
84861480783
-
Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human
-
Shah DK, Betts AM. 2012. Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human. J. Pharmacokinet. Pharmacodyn. 39:67-86.
-
(2012)
J. Pharmacokinet. Pharmacodyn.
, vol.39
, pp. 67-86
-
-
Shah, D.K.1
Betts, A.M.2
-
63
-
-
34748905976
-
Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment
-
Yang RS, Chang LW, Wu JP, Tsai MH, Wang HJ, Kuo YC, Yeh TK, Yang CS, Lin P. 2007. Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment. Environ. Health Perspect. 115:1339-1343.
-
(2007)
Environ. Health Perspect.
, vol.115
, pp. 1339-1343
-
-
Yang, R.S.1
Chang, L.W.2
Wu, J.P.3
Tsai, M.H.4
Wang, H.J.5
Kuo, Y.C.6
Yeh, T.K.7
Yang, C.S.8
Lin, P.9
-
65
-
-
67649991190
-
Population modeling and Monte Carlo simulation study of the pharmacokinetics and antituberculosis pharmacodynamics of rifampin in lungs
-
Goutelle S, Bourguignon L, Maire PH, Van Guilder M, Conte JE, Jr, Jelliffe RW. 2009. Population modeling and Monte Carlo simulation study of the pharmacokinetics and antituberculosis pharmacodynamics of rifampin in lungs. Antimicrob. Agents Chemother. 53:2974-2981.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 2974-2981
-
-
Goutelle, S.1
Bourguignon, L.2
Maire, P.H.3
Van Guilder, M.4
Conte Jr., J.E.5
Jelliffe, R.W.6
-
66
-
-
84455169868
-
Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions
-
Kjellsson MC, Via LE, Goh A, Weiner D, Low KM, Kern S, Pillai G, Barry CE, III, Dartois V. 2012. Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions. Antimicrob. Agents Chemother. 56:446-457.
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 446-457
-
-
Kjellsson, M.C.1
Via, L.E.2
Goh, A.3
Weiner, D.4
Low, K.M.5
Kern, S.6
Pillai, G.7
Barry Iii, C.E.8
Dartois, V.9
-
67
-
-
0014889613
-
Chemical and biological properties of rifampicin
-
Furesz S. 1970. Chemical and biological properties of rifampicin. Antibiot. Chemother. 16:316-351.
-
(1970)
Antibiot. Chemother.
, vol.16
, pp. 316-351
-
-
Furesz, S.1
-
68
-
-
0017944237
-
Clinical pharmacokinetics of rifampicin
-
Acocella G. 1978. Clinical pharmacokinetics of rifampicin. Clin. Pharmacokinet. 3:108-127.
-
(1978)
Clin. Pharmacokinet.
, vol.3
, pp. 108-127
-
-
Acocella, G.1
-
69
-
-
44449128516
-
Population pharmacokinetics of rifampin in pulmonary tuberculosis patients, including a semimechanistic model to describe variable absorption
-
Wilkins JJ, Savic RM, Karlsson MO, Langdon G, McIlleron H, Pillai G, Smith PJ, Simonsson US. 2008. Population pharmacokinetics of rifampin in pulmonary tuberculosis patients, including a semimechanistic model to describe variable absorption. Antimicrob. Agents Chemother. 52:2138-2148.
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 2138-2148
-
-
Wilkins, J.J.1
Savic, R.M.2
Karlsson, M.O.3
Langdon, G.4
McIlleron, H.5
Pillai, G.6
Smith, P.J.7
Simonsson, U.S.8
-
70
-
-
33646092056
-
Revised assessment of cancer risk to dichloromethane: Part i Bayesian PBPK and dose-response modeling in mice
-
Marino DJ, Clewell HJ, Gentry PR, Covington TR, Hack CE, David RM, Morgott DA. 2006. Revised assessment of cancer risk to dichloromethane: part I Bayesian PBPK and dose-response modeling in mice. Regul. Toxicol. Pharmacol. 45:44-54.
-
(2006)
Regul. Toxicol. Pharmacol.
, vol.45
, pp. 44-54
-
-
Marino, D.J.1
Clewell, H.J.2
Gentry, P.R.3
Covington, T.R.4
Hack, C.E.5
David, R.M.6
Morgott, D.A.7
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