Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

Nature Medicine

Volumn 20, Issue 1, 2014, Pages 75-79

  Lin, Philana Ling ^a   Ford, Christopher B ^b,c   Coleman, M Teresa ^d   Myers, Amy J ^d   Gawande, Richa ^b   Ioerger, Thomas ^e   Sacchettini, James ^e   Fortune, Sarah M ^b,c,f   Flynn, Joanne L ^d  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e TEXAS A AND M UNIVERSITY   (United States)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL LOAD; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATE; COLONY FORMING UNIT; CONTROLLED STUDY; GRANULOMA; HISTOPATHOLOGY; LATENT TUBERCULOSIS; LUNG LESION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL;

ANIMALIA; BACTERIA (MICROORGANISMS); MACACA; MYCOBACTERIUM TUBERCULOSIS;

ADAPTIVE IMMUNITY; ANIMALS; DISEASE PROGRESSION; GRANULOMA; ISONIAZID; LATENT TUBERCULOSIS; LUNG; MACACA FASCICULARIS; MODELS, BIOLOGICAL; MYCOBACTERIUM TUBERCULOSIS; POPULATION DYNAMICS; POSITRON-EMISSION TOMOGRAPHY; TUBERCULOSIS;

EID: 84891853921     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3412     Document Type: Article

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