Impact of folic acid fortification on global DNA methylation and one-carbon biomarkers in the Women's Health Initiative Observational Study cohort

Epigenetics

Volumn 9, Issue 3, 2013, Pages 396-403

  Bae, Sajin ^a   Ulrich, Cornelia M ^b,c   Bailey, Lynn B ^d   Malysheva, Olga ^a   Brown, Elissa C ^b   Maneval, David R ^e   Neuhouser, Marian L ^b   Cheng, Ting Yuan David ^b   Miller, Joshua W ^f,g   Zheng, Yingye ^b   Xiao, Liren ^b   Hou, Lifang ^h   Song, Xiaoling ^b   Buck, Katharina ^c   Beresford, Shirley A A ^b   Caudill, Marie A ^a  

^a Department of Obstetrics Gynecology   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d UNIVERSITY OF GEORGIA   (United States)

^e UNIVERSITY OF FLORIDA   (United States)

^f RUTGERS UNIVERSITY   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Choline; DNA methylation; Folate; Folic acid fortification; Homocysteine; One carbon biomarkers; Postmenopausal women; RBC folate; Vitamin B12; Women's Health Initiative

Indexed keywords

5, 10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); BETAINE; BIOLOGICAL MARKER; CHOLINE; CYANOCOBALAMIN; CYSTEINE; DIMETHYLGLYCINE; FOLIC ACID; HOMOCYSTEINE; METHYLMALONIC ACID; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CARBON METABOLISM; CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA METHYLATION; ERYTHROCYTE; FEMALE; FOLIC ACID FORTIFICATION; GENOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LEUKOCYTE; OBSERVATIONAL STUDY; PLASMA; POSTMENOPAUSE;

CHOLINE; DNA METHYLATION; FOLATE; FOLIC ACID FORTIFICATION; HOMOCYSTEINE; ONE-CARBON BIOMARKERS; POSTMENOPAUSAL WOMEN; RBC FOLATE; VITAMIN B12; WOMEN'S HEALTH INITIATIVE;

AGED; BIOLOGICAL MARKERS; CHOLINE; COHORT STUDIES; DNA METHYLATION; FEMALE; FOLIC ACID; FOOD, FORTIFIED; HOMOCYSTEINE; HUMANS; LEUKOCYTES; MIDDLE AGED; POSTMENOPAUSE;

EID: 84899155341     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.27323     Document Type: Article

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