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Volumn 68, Issue 24, 2008, Pages 10280-10289

Methylation of polycomb target genes in intestinal cancer is mediated by inflammation

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[No Author keywords available]

Indexed keywords

POLYCOMB GROUP PROTEIN;

EID: 57749090255     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-1957     Document Type: Article
Times cited : (187)

References (48)
  • 1
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007;128:683-92.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 3
    • 0032401808 scopus 로고    scopus 로고
    • Aging and DNA methylation in colorectal mucosa and cancer
    • Ahuja N, Li Q, Mohan AL, Baylin SB, Issa JP. Aging and DNA methylation in colorectal mucosa and cancer. Cancer Res 1998;58:5489-94.
    • (1998) Cancer Res , vol.58 , pp. 5489-5494
    • Ahuja, N.1    Li, Q.2    Mohan, A.L.3    Baylin, S.B.4    Issa, J.P.5
  • 4
    • 0037380886 scopus 로고    scopus 로고
    • Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia
    • Holst CR, Nuovo GJ, Esteller M, et al. Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia. Cancer Res 2003;63:1596-601.
    • (2003) Cancer Res , vol.63 , pp. 1596-1601
    • Holst, C.R.1    Nuovo, G.J.2    Esteller, M.3
  • 5
    • 33845333815 scopus 로고    scopus 로고
    • Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue
    • Yan PS, Venkataramu C, Ibrahim A, et al. Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue. Clin Cancer Res 2006;12:6626-36.
    • (2006) Clin Cancer Res , vol.12 , pp. 6626-6636
    • Yan, P.S.1    Venkataramu, C.2    Ibrahim, A.3
  • 6
    • 34447625911 scopus 로고    scopus 로고
    • Epigenetics and aging: The targets and the marks
    • Fraga MF, Esteller M. Epigenetics and aging: the targets and the marks. Trends Genet 2007;23:413-8.
    • (2007) Trends Genet , vol.23 , pp. 413-418
    • Fraga, M.F.1    Esteller, M.2
  • 7
    • 18644382388 scopus 로고    scopus 로고
    • The polycomb group protein EZH2 is involved in progression of prostate cancer
    • Varambally S, Dhanasekaran SM, Zhou M, et al. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature 2002;419:624-9.
    • (2002) Nature , vol.419 , pp. 624-629
    • Varambally, S.1    Dhanasekaran, S.M.2    Zhou, M.3
  • 8
    • 35148840173 scopus 로고    scopus 로고
    • Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma
    • Bruggeman SW, Hulsman D, Tanger E, et al. Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma. Cancer Cell 2007;12:328-41.
    • (2007) Cancer Cell , vol.12 , pp. 328-341
    • Bruggeman, S.W.1    Hulsman, D.2    Tanger, E.3
  • 9
    • 44349131472 scopus 로고    scopus 로고
    • Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation
    • Kondo Y, Shen L, Cheng AS, et al. Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat Genet 2008;40:741-50.
    • (2008) Nat Genet , vol.40 , pp. 741-750
    • Kondo, Y.1    Shen, L.2    Cheng, A.S.3
  • 10
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein BE, Mikkelsen TS, Xie X, et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 2006;125:315-26.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3
  • 11
    • 33646882068 scopus 로고    scopus 로고
    • Polycomb complexes repress developmental regulators in murine embryonic stem cells
    • Boyer LA, Plath K, Zeitlinger J, et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 2006;441:349-53.
    • (2006) Nature , vol.441 , pp. 349-353
    • Boyer, L.A.1    Plath, K.2    Zeitlinger, J.3
  • 12
    • 33646870495 scopus 로고    scopus 로고
    • Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
    • Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 2006;20:1123-36.
    • (2006) Genes Dev , vol.20 , pp. 1123-1136
    • Bracken, A.P.1    Dietrich, N.2    Pasini, D.3    Hansen, K.H.4    Helin, K.5
  • 13
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Lee TI, Jenner RG, Boyer LA, et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 2006;125:301-13.
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3
  • 14
    • 0036830642 scopus 로고    scopus 로고
    • Role of histone H3 lysine 27 methylation in Polycomb-group silencing
    • Cao R, Wang L, Wang H, et al. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 2002;298:1039-43.
    • (2002) Science , vol.298 , pp. 1039-1043
    • Cao, R.1    Wang, L.2    Wang, H.3
  • 15
    • 0037131523 scopus 로고    scopus 로고
    • Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites
    • Czermin B, Melfi R, McCabe D, Seitz V, Imhof A, Pirrotta V. Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell 2002;111:185-96.
    • (2002) Cell , vol.111 , pp. 185-196
    • Czermin, B.1    Melfi, R.2    McCabe, D.3    Seitz, V.4    Imhof, A.5    Pirrotta, V.6
  • 16
    • 3042801308 scopus 로고    scopus 로고
    • SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex
    • Cao R, Zhang Y. SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex. Mol Cell 2004;15:57-67.
    • (2004) Mol Cell , vol.15 , pp. 57-67
    • Cao, R.1    Zhang, Y.2
  • 17
    • 33748055105 scopus 로고    scopus 로고
    • MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells
    • Rauch T, Li H, Wu X, Pfeifer GP. MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells. Cancer Res 2006;66:7939-47.
    • (2006) Cancer Res , vol.66 , pp. 7939-7947
    • Rauch, T.1    Li, H.2    Wu, X.3    Pfeifer, G.P.4
  • 18
    • 33846569960 scopus 로고    scopus 로고
    • A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
    • Ohm JE, McGarvey KM, Yu X, et al. A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet 2007;39:237-42.
    • (2007) Nat Genet , vol.39 , pp. 237-242
    • Ohm, J.E.1    McGarvey, K.M.2    Yu, X.3
  • 19
    • 34248361968 scopus 로고    scopus 로고
    • Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay
    • Rauch T, Wang Z, Zhang X, et al. Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay. Proc Natl Acad Sci U S A 2007;104:5527-32.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 5527-5532
    • Rauch, T.1    Wang, Z.2    Zhang, X.3
  • 20
    • 33846649587 scopus 로고    scopus 로고
    • Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
    • Schlesinger Y, Straussman R, Keshet I, et al. Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet 2007;39:232-6.
    • (2007) Nat Genet , vol.39 , pp. 232-236
    • Schlesinger, Y.1    Straussman, R.2    Keshet, I.3
  • 21
    • 33846576622 scopus 로고    scopus 로고
    • Epigenetic stem cell signature in cancer
    • Widschwendter M, Fiegl H, Egle D, et al. Epigenetic stem cell signature in cancer. Nat Genet 2007;39:157-8.
    • (2007) Nat Genet , vol.39 , pp. 157-158
    • Widschwendter, M.1    Fiegl, H.2    Egle, D.3
  • 22
    • 20344376407 scopus 로고    scopus 로고
    • Mechanisms of disease: Inflammation and the origins of cancer
    • Moss SF, Blaser MJ. Mechanisms of disease: inflammation and the origins of cancer. Nat Clin Pract Oncol 2005;2:90-7.
    • (2005) Nat Clin Pract Oncol , vol.2 , pp. 90-97
    • Moss, S.F.1    Blaser, M.J.2
  • 24
    • 33646160623 scopus 로고    scopus 로고
    • Inflammation, a key event in cancer development
    • Lu H, Ouyang W, Huang C. Inflammation, a key event in cancer development. Mol Cancer Res 2006;4:221-33.
    • (2006) Mol Cancer Res , vol.4 , pp. 221-233
    • Lu, H.1    Ouyang, W.2    Huang, C.3
  • 25
    • 10744221150 scopus 로고    scopus 로고
    • Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis
    • Rutter M, Saunders B, Wilkinson K, et al. Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis. Gastroenterology 2004;126:451-9.
    • (2004) Gastroenterology , vol.126 , pp. 451-459
    • Rutter, M.1    Saunders, B.2    Wilkinson, K.3
  • 26
    • 0031012926 scopus 로고    scopus 로고
    • T cell receptor-α β-deficient mice fail to develop colitis in the absence of a microbial environment
    • Dianda L, Hanby AM, Wright NA, Sebesteny A, Hayday AC, Owen MJ. T cell receptor-α β-deficient mice fail to develop colitis in the absence of a microbial environment. Am J Pathol 1997;150:91-7.
    • (1997) Am J Pathol , vol.150 , pp. 91-97
    • Dianda, L.1    Hanby, A.M.2    Wright, N.A.3    Sebesteny, A.4    Hayday, A.C.5    Owen, M.J.6
  • 27
    • 0032412057 scopus 로고    scopus 로고
    • Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
    • Sellon RK, Tonkonogy S, Schultz M, et al. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 1998;66:5224-31.
    • (1998) Infect Immun , vol.66 , pp. 5224-5231
    • Sellon, R.K.1    Tonkonogy, S.2    Schultz, M.3
  • 28
    • 0037112436 scopus 로고    scopus 로고
    • Elimination of colon cancer in germ-free transforming growth factor β1-deficient mice
    • Engle SJ, Ormsby I, Pawlowski S, et al. Elimination of colon cancer in germ-free transforming growth factor β1-deficient mice. Cancer Res 2002;62:6362-6.
    • (2002) Cancer Res , vol.62 , pp. 6362-6366
    • Engle, S.J.1    Ormsby, I.2    Pawlowski, S.3
  • 29
    • 33846331650 scopus 로고    scopus 로고
    • Oxidative stress and cancer: Have we moved forward?
    • Halliwell B. Oxidative stress and cancer: have we moved forward? Biochem J 2007;401:1-11.
    • (2007) Biochem J , vol.401 , pp. 1-11
    • Halliwell, B.1
  • 30
    • 0035896545 scopus 로고    scopus 로고
    • Production of brominating intermediates by myeloperoxidase. A transhalogenation pathway for generating mutagenic nucleobases during inflammation
    • Henderson JP, Byun J, Williams MV, Mueller DM, McCormick ML, Heinecke JW. Production of brominating intermediates by myeloperoxidase. A transhalogenation pathway for generating mutagenic nucleobases during inflammation. J Biol Chem 2001;276:7867-75.
    • (2001) J Biol Chem , vol.276 , pp. 7867-7875
    • Henderson, J.P.1    Byun, J.2    Williams, M.V.3    Mueller, D.M.4    McCormick, M.L.5    Heinecke, J.W.6
  • 31
    • 4444339833 scopus 로고    scopus 로고
    • Oxidative DNA damage and disease: Induction, repair and significance
    • Evans MD, Dizdaroglu M, Cooke MS. Oxidative DNA damage and disease: induction, repair and significance. Mutat Res 2004;567:1-61.
    • (2004) Mutat Res , vol.567 , pp. 1-61
    • Evans, M.D.1    Dizdaroglu, M.2    Cooke, M.S.3
  • 32
    • 10944248830 scopus 로고    scopus 로고
    • Endogenous formation of novel halogenated 2′-deoxycytidine. Hypohalous acid-mediated DNA modification at the site of inflammation
    • Kawai Y, Morinaga H, Kondo H, et al. Endogenous formation of novel halogenated 2′-deoxycytidine. Hypohalous acid-mediated DNA modification at the site of inflammation. J Biol Chem 2004;279:51241-9.
    • (2004) J Biol Chem , vol.279 , pp. 51241-51249
    • Kawai, Y.1    Morinaga, H.2    Kondo, H.3
  • 33
    • 34250860821 scopus 로고    scopus 로고
    • Inflammation-mediated cytosine damage: A mechanistic link between inflammation and the epigenetic alterations in human cancers
    • Valinluck V, Sowers LC. Inflammation-mediated cytosine damage: a mechanistic link between inflammation and the epigenetic alterations in human cancers. Cancer Res 2007;67:5583-6.
    • (2007) Cancer Res , vol.67 , pp. 5583-5586
    • Valinluck, V.1    Sowers, L.C.2
  • 34
    • 33847055935 scopus 로고    scopus 로고
    • Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1
    • Valinluck V, Sowers LC. Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1. Cancer Res 2007;67:946-50.
    • (2007) Cancer Res , vol.67 , pp. 946-950
    • Valinluck, V.1    Sowers, L.C.2
  • 36
    • 0842304289 scopus 로고    scopus 로고
    • Bacteria-induced intestinal cancer in mice with disrupted Gpx1 and Gpx2 genes
    • Chu FF, Esworthy RS, Chu PG, et al. Bacteria-induced intestinal cancer in mice with disrupted Gpx1 and Gpx2 genes. Cancer Res 2004;64:962-8.
    • (2004) Cancer Res , vol.64 , pp. 962-968
    • Chu, F.F.1    Esworthy, R.S.2    Chu, P.G.3
  • 37
    • 33750543992 scopus 로고    scopus 로고
    • Mutation accumulation in the intestine and colon of mice deficient in two intracellular glutathione peroxidases
    • Lee DH, Esworthy RS, Chu C, Pfeifer GP, Chu FF. Mutation accumulation in the intestine and colon of mice deficient in two intracellular glutathione peroxidases. Cancer Res 2006;66:9845-51.
    • (2006) Cancer Res , vol.66 , pp. 9845-9851
    • Lee, D.H.1    Esworthy, R.S.2    Chu, C.3    Pfeifer, G.P.4    Chu, F.F.5
  • 38
    • 0031879339 scopus 로고    scopus 로고
    • Selenium-dependent glutathione peroxidase-GI is a major glutathione peroxidase activity in the mucosal epithelium of rodent intestine
    • Esworthy RS, Swiderek KM, Ho YS, Chu FF. Selenium-dependent glutathione peroxidase-GI is a major glutathione peroxidase activity in the mucosal epithelium of rodent intestine. Biochim Biophys Acta 1998;1381:213-26.
    • (1998) Biochim Biophys Acta , vol.1381 , pp. 213-226
    • Esworthy, R.S.1    Swiderek, K.M.2    Ho, Y.S.3    Chu, F.F.4
  • 39
    • 27744443057 scopus 로고    scopus 로고
    • Methylated-CpG island recovery assay: A new technique for the rapid detection of methylated-CpG islands in cancer
    • Rauch T, Pfeifer GP. Methylated-CpG island recovery assay: a new technique for the rapid detection of methylated-CpG islands in cancer. Lab Invest 2005;85:1172-80.
    • (2005) Lab Invest , vol.85 , pp. 1172-1180
    • Rauch, T.1    Pfeifer, G.P.2
  • 40
    • 38349135680 scopus 로고    scopus 로고
    • High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer
    • Rauch TA, Zhong X, Wu X, et al. High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer. Proc Natl Acad Sci U S A 2008;105:252-7.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 252-257
    • Rauch, T.A.1    Zhong, X.2    Wu, X.3
  • 41
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: A sensitive and quantitative DNA methylation assay
    • Xiong Z, Laird PW. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res 1997;25:2532-4.
    • (1997) Nucleic Acids Res , vol.25 , pp. 2532-2534
    • Xiong, Z.1    Laird, P.W.2
  • 42
    • 38549129312 scopus 로고    scopus 로고
    • CTCF is the master organizer of domain-wide allele-specific chromatin at the H19/Igf2 imprinted region
    • Han L, Lee DH, Szabo PE. CTCF is the master organizer of domain-wide allele-specific chromatin at the H19/Igf2 imprinted region. Mol Cell Biol 2008;28:1124-35.
    • (2008) Mol Cell Biol , vol.28 , pp. 1124-1135
    • Han, L.1    Lee, D.H.2    Szabo, P.E.3
  • 43
    • 27744570398 scopus 로고    scopus 로고
    • Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy
    • Frigola J, Munoz M, Clark SJ, Moreno V, Capella G, Peinado MA. Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy. Oncogene 2005;24:7320-6.
    • (2005) Oncogene , vol.24 , pp. 7320-7326
    • Frigola, J.1    Munoz, M.2    Clark, S.J.3    Moreno, V.4    Capella, G.5    Peinado, M.A.6
  • 44
    • 35349020543 scopus 로고    scopus 로고
    • Transcriptional silencing of hedgehog-interacting protein by CpG hypermethylation and chromatic structure in human gastrointestinal cancer
    • Taniguchi H, Yamamoto H, Akutsu N, et al. Transcriptional silencing of hedgehog-interacting protein by CpG hypermethylation and chromatic structure in human gastrointestinal cancer. J Pathol 2007;213:131-9.
    • (2007) J Pathol , vol.213 , pp. 131-139
    • Taniguchi, H.1    Yamamoto, H.2    Akutsu, N.3
  • 45
    • 42349108108 scopus 로고    scopus 로고
    • Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer
    • Zhang W, Glockner SC, Guo M, et al. Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer. Cancer Res 2008;68:2764-72.
    • (2008) Cancer Res , vol.68 , pp. 2764-2772
    • Zhang, W.1    Glockner, S.C.2    Guo, M.3
  • 46
  • 47
    • 0141537154 scopus 로고    scopus 로고
    • Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation
    • Kang GH, Lee HJ, Hwang KS, Lee S, Kim JH, Kim JS. Aberrant CpG island hypermethylation of chronic gastritis, in relation to aging, gender, intestinal metaplasia, and chronic inflammation. Am J Pathol 2003;163:1551-6.
    • (2003) Am J Pathol , vol.163 , pp. 1551-1556
    • Kang, G.H.1    Lee, H.J.2    Hwang, K.S.3    Lee, S.4    Kim, J.H.5    Kim, J.S.6
  • 48
    • 32944459562 scopus 로고    scopus 로고
    • High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk
    • Maekita T, Nakazawa K, Mihara M, et al. High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk. Clin Cancer Res 2006;12:989-95.
    • (2006) Clin Cancer Res , vol.12 , pp. 989-995
    • Maekita, T.1    Nakazawa, K.2    Mihara, M.3


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