-
1
-
-
84903279814
-
Regulation of pyruvate metabolism and human disease
-
CrossRef PubMed
-
Gray, L.R., Tompkins, S.C. and Taylor, E.B. (2014) Regulation of pyruvate metabolism and human disease. Cellular and molecular life sciences: Cell. Mol. Life Sci. 71, 2577-2604 CrossRef PubMed
-
(2014)
Cellular and Molecular Life Sciences: Cell. Mol. Life Sci.
, vol.71
, pp. 2577-2604
-
-
Gray, L.R.1
Tompkins, S.C.2
Taylor, E.B.3
-
2
-
-
0010501961
-
Comparative properties of glutamic-alanine transaminase from several sources
-
CrossRef PubMed
-
Hopper, S. and Segal, H.L. (1964) Comparative properties of glutamic-alanine transaminase from several sources. Arch. Biochem. Biophys. 105, 501-505 CrossRef PubMed
-
(1964)
Arch. Biochem. Biophys.
, vol.105
, pp. 501-505
-
-
Hopper, S.1
Segal, H.L.2
-
3
-
-
0016808194
-
The involvement of mitochondrial pyruvate transport in the pathways of gluconeogenesis from serine and alanine in isolated rat and mouse liver cells
-
CrossRef PubMed
-
Mendes-Mourao, J., Halestrap, A.P., Crisp, D.M. and Pogson, C.I. (1975) The involvement of mitochondrial pyruvate transport in the pathways of gluconeogenesis from serine and alanine in isolated rat and mouse liver cells. FEBS Lett. 53, 29-32 CrossRef PubMed
-
(1975)
FEBS Lett.
, vol.53
, pp. 29-32
-
-
Mendes-Mourao, J.1
Halestrap, A.P.2
Crisp, D.M.3
Pogson, C.I.4
-
4
-
-
0000929743
-
Lactic dehydrogenases: Functions of the two types rates of synthesis of the two major forms can be correlated with metabolic differentiation
-
CrossRef PubMed
-
Dawson, D.M., Goodfriend, T.L. and Kaplan, N.O. (1964) Lactic dehydrogenases: functions of the two types rates of synthesis of the two major forms can be correlated with metabolic differentiation. Science 143, 929-933 CrossRef PubMed
-
(1964)
Science
, vol.143
, pp. 929-933
-
-
Dawson, D.M.1
Goodfriend, T.L.2
Kaplan, N.O.3
-
5
-
-
37049236727
-
Nature and development of lactic dehydrogenases: The two major types of this enzyme form molecular hybrids which change in makeup during development
-
CrossRef PubMed
-
Cahn, R.D., Zwilling, E., Kaplan, N.O. and Levine, L. (1962) Nature and development of lactic dehydrogenases: the two major types of this enzyme form molecular hybrids which change in makeup during development. Science 136, 962-969 CrossRef PubMed
-
(1962)
Science
, vol.136
, pp. 962-969
-
-
Cahn, R.D.1
Zwilling, E.2
Kaplan, N.O.3
Levine, L.4
-
6
-
-
84859777452
-
The role of VDAC in cell death: Friend or foe?
-
CrossRef PubMed
-
McCommis, K.S. and Baines, C.P. (2012) The role of VDAC in cell death: friend or foe? Biochim. Biophys. Acta 1818, 1444-1450 CrossRef PubMed
-
(2012)
Biochim. Biophys. Acta
, vol.1818
, pp. 1444-1450
-
-
McCommis, K.S.1
Baines, C.P.2
-
7
-
-
0029914301
-
Deficiency of the voltage-dependent anion channel: A novel cause of mitochondriopathy
-
CrossRef PubMed
-
Huizing, M., Ruitenbeek, W., Thinnes, F.P., DePinto, V., Wendel, U., Trijbels, F.J., Smit, L.M., ter Laak, H.J. and van den Heuvel, L.P. (1996) Deficiency of the voltage-dependent anion channel: a novel cause of mitochondriopathy. Pediatr. Res. 39, 760-765 CrossRef PubMed
-
(1996)
Pediatr. Res.
, vol.39
, pp. 760-765
-
-
Huizing, M.1
Ruitenbeek, W.2
Thinnes, F.P.3
DePinto, V.4
Wendel, U.5
Trijbels, F.J.6
Smit, L.M.7
Ter Laak, H.J.8
Van Den Heuvel, L.P.9
-
8
-
-
0012794265
-
Mitochondria metabolite transport
-
CrossRef PubMed
-
Klingenberg, M. (1970) Mitochondria metabolite transport. FEBS Lett. 6, 145-154 CrossRef PubMed
-
(1970)
FEBS Lett.
, vol.6
, pp. 145-154
-
-
Klingenberg, M.1
-
9
-
-
49649152971
-
The transport of pyruvate in rat liver mitochondria
-
CrossRef PubMed
-
Papa, S., Francavilla, A., Paradies, G. and Meduri, B. (1971) The transport of pyruvate in rat liver mitochondria. FEBS Lett. 12, 285-288 CrossRef PubMed
-
(1971)
FEBS Lett.
, vol.12
, pp. 285-288
-
-
Papa, S.1
Francavilla, A.2
Paradies, G.3
Meduri, B.4
-
10
-
-
49649141715
-
Pyruvate uptake in rat liver mitochondria: Transport or adsorption?
-
CrossRef PubMed
-
Zahlten, R.N., Hochberg, A.A., Stratman, F.W. and Lardy, H.A. (1972) Pyruvate uptake in rat liver mitochondria: transport or adsorption? FEBS Lett. 21, 11-13 CrossRef PubMed
-
(1972)
FEBS Lett.
, vol.21
, pp. 11-13
-
-
Zahlten, R.N.1
Hochberg, A.A.2
Stratman, F.W.3
Lardy, H.A.4
-
11
-
-
0015820808
-
Substrate anion transport in mitochondria
-
CrossRef PubMed
-
Brouwer, A., Smits, G.G., Tas, J., Meijer, A.J. and Tager, J.M. (1973) Substrate anion transport in mitochondria. Biochimie 55, 717-725 CrossRef PubMed
-
(1973)
Biochimie
, vol.55
, pp. 717-725
-
-
Brouwer, A.1
Smits, G.G.2
Tas, J.3
Meijer, A.J.4
Tager, J.M.5
-
12
-
-
0016299207
-
On the mechanism of translocation of pyruvate and other monocarboxylic acids in rat-liver mitochondria
-
CrossRef PubMed
-
Papa, S. and Paradies, G. (1974) On the mechanism of translocation of pyruvate and other monocarboxylic acids in rat-liver mitochondria. Eur. J. Biochem. 49, 265-274 CrossRef PubMed
-
(1974)
Eur. J. Biochem.
, vol.49
, pp. 265-274
-
-
Papa, S.1
Paradies, G.2
-
13
-
-
0015973650
-
Specific inhibition of pyruvate transport in rat liver mitochondria and human erythrocytes by alpha-cyano-4-hydroxycinnamate
-
PubMed
-
Halestrap, A.P. and Denton, R.M. (1974) Specific inhibition of pyruvate transport in rat liver mitochondria and human erythrocytes by alpha-cyano-4-hydroxycinnamate. Biochem. J. 138, 313-316 PubMed
-
(1974)
Biochem. J.
, vol.138
, pp. 313-316
-
-
Halestrap, A.P.1
Denton, R.M.2
-
14
-
-
0016756374
-
The mitochondrial pyruvate carrier. Kinetics and specificity for substrates and inhibitors
-
PubMed
-
Halestrap, A.P. (1975) The mitochondrial pyruvate carrier. Kinetics and specificity for substrates and inhibitors. Biochem. J. 148, 85-96 PubMed
-
(1975)
Biochem. J.
, vol.148
, pp. 85-96
-
-
Halestrap, A.P.1
-
15
-
-
0023756857
-
The effect of doxorubicin on the transport of pyruvate in rat-heart mitochondria
-
CrossRef PubMed
-
Paradies, G. and Ruggiero, F.M. (1988) The effect of doxorubicin on the transport of pyruvate in rat-heart mitochondria. Biochem. Biophys. Res. Commun. 156, 1302-1307 CrossRef PubMed
-
(1988)
Biochem. Biophys. Res. Commun.
, vol.156
, pp. 1302-1307
-
-
Paradies, G.1
Ruggiero, F.M.2
-
16
-
-
0020553341
-
The mitochondrial phosphate carrier reconstituted in liposomes is inhibited by doxorubicin
-
CrossRef PubMed
-
Cheneval, D., Muller, M. and Carafoli, E. (1983) The mitochondrial phosphate carrier reconstituted in liposomes is inhibited by doxorubicin. FEBS Lett. 159, 123-126 CrossRef PubMed
-
(1983)
FEBS Lett.
, vol.159
, pp. 123-126
-
-
Cheneval, D.1
Muller, M.2
Carafoli, E.3
-
17
-
-
50549088465
-
The inhibition of gluconeogenesis by gatifloxacin may contribute to its hypoglycaemic action
-
CrossRef PubMed
-
Drozak, J., Miecznik, A., Jarzyna, R. and Bryla, J. (2008) The inhibition of gluconeogenesis by gatifloxacin may contribute to its hypoglycaemic action. Eur. J. Pharmacol. 594, 39-43 CrossRef PubMed
-
(2008)
Eur. J. Pharmacol.
, vol.594
, pp. 39-43
-
-
Drozak, J.1
Miecznik, A.2
Jarzyna, R.3
Bryla, J.4
-
18
-
-
84855185441
-
Metabolic effects of silibinin in the rat liver
-
CrossRef PubMed
-
Colturato, C.P., Constantin, R.P., Maeda, Jr, A.S., Constantin, R.P., Yamamoto, N.S., Bracht, A., Ishii-Iwamoto, E.L. and Constantin, J. (2012) Metabolic effects of silibinin in the rat liver. Chem.-Bio. Interact. 195, 119-132 CrossRef PubMed
-
(2012)
Chem.-Bio. Interact.
, vol.195
, pp. 119-132
-
-
Colturato, C.P.1
Constantin, R.P.2
Maeda, A.S.3
Constantin, R.P.4
Yamamoto, N.S.5
Bracht, A.6
Ishii-Iwamoto, E.L.7
Constantin, J.8
-
19
-
-
84890345210
-
Inhibition of mitochondrial pyruvate transport by zaprinast causes massive accumulation of aspartate at the expense of glutamate in the retina
-
CrossRef PubMed
-
Du, J., Cleghorn, W.M., Contreras, L., Lindsay, K., Rountree, A.M., Chertov, A.O., Turner, S.J., Sahaboglu, A., Linton, J., Sadilek, M. et al. (2013) Inhibition of mitochondrial pyruvate transport by zaprinast causes massive accumulation of aspartate at the expense of glutamate in the retina. J. Biol. Chem. 288, 36129-36140 CrossRef PubMed
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 36129-36140
-
-
Du, J.1
Cleghorn, W.M.2
Contreras, L.3
Lindsay, K.4
Rountree, A.M.5
Chertov, A.O.6
Turner, S.J.7
Sahaboglu, A.8
Linton, J.9
Sadilek, M.10
-
20
-
-
18044372809
-
Identification and characterisation of a new class of highly specific and potent inhibitors of the mitochondrial pyruvate carrier
-
CrossRef PubMed
-
Hildyard, J.C., Ammala, C., Dukes, I.D., Thomson, S.A. and Halestrap, A.P. (2005) Identification and characterisation of a new class of highly specific and potent inhibitors of the mitochondrial pyruvate carrier. Biochim. Biophys. Acta 1707, 221-230 CrossRef PubMed
-
(2005)
Biochim. Biophys. Acta
, vol.1707
, pp. 221-230
-
-
Hildyard, J.C.1
Ammala, C.2
Dukes, I.D.3
Thomson, S.A.4
Halestrap, A.P.5
-
21
-
-
0016814829
-
The specificity and metabolic implications of the inhibition of pyruvate transport in isolated mitochondria and intact tissue preparations by alpha-cyano-4-hydroxycinnamate and related compounds
-
PubMed
-
Halestrap, A.P. and Denton, R.M. (1975) The specificity and metabolic implications of the inhibition of pyruvate transport in isolated mitochondria and intact tissue preparations by alpha-cyano-4-hydroxycinnamate and related compounds. Biochem. J. 148, 97-106 PubMed
-
(1975)
Biochem. J.
, vol.148
, pp. 97-106
-
-
Halestrap, A.P.1
Denton, R.M.2
-
22
-
-
0017249095
-
The mechanism of the inhibition of the mitochondrial pyruvate transporter by alpha-cyanocinnamate derivatives
-
PubMed
-
Halestrap, A.P. (1976) The mechanism of the inhibition of the mitochondrial pyruvate transporter by alpha-cyanocinnamate derivatives. Biochem. J. 156, 181-183 PubMed
-
(1976)
Biochem. J.
, vol.156
, pp. 181-183
-
-
Halestrap, A.P.1
-
23
-
-
84875858252
-
Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier
-
CrossRef PubMed
-
Divakaruni, A.S., Wiley, S.E., Rogers, G.W., Andreyev, A.Y., Petrosyan, S., Loviscach, M., Wall, E.A., Yadava, N., Heuck, A.P., Ferrick, D.A. et al. (2013) Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier. Proc. Natl. Acad. Sci. U.S.A. 110, 5422-5427 CrossRef PubMed
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 5422-5427
-
-
Divakaruni, A.S.1
Wiley, S.E.2
Rogers, G.W.3
Andreyev, A.Y.4
Petrosyan, S.5
Loviscach, M.6
Wall, E.A.7
Yadava, N.8
Heuck, A.P.9
Ferrick, D.A.10
-
24
-
-
84877771544
-
Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT) - relationship to newly identified mitochondrial pyruvate carrier proteins
-
CrossRef PubMed
-
Colca, J.R., McDonald, W.G., Cavey, G.S., Cole, S.L., Holewa, D.D., Brightwell-Conrad, A.S., Wolfe, C.L., Wheeler, J.S., Coulter, K.R., Kilkuskie, P.M. et al. (2013) Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT) - relationship to newly identified mitochondrial pyruvate carrier proteins. PLoS ONE 8, e61551 CrossRef PubMed
-
(2013)
PLoS ONE
, vol.8
-
-
Colca, J.R.1
McDonald, W.G.2
Cavey, G.S.3
Cole, S.L.4
Holewa, D.D.5
Brightwell-Conrad, A.S.6
Wolfe, C.L.7
Wheeler, J.S.8
Coulter, K.R.9
Kilkuskie, P.M.10
-
25
-
-
0017845913
-
Pyruvate and ketone-body transport across the mitochondrial membrane. Exchange properties, pH-dependence and mechanism of the carrier
-
PubMed
-
Halestrap, A.P. (1978) Pyruvate and ketone-body transport across the mitochondrial membrane. Exchange properties, pH-dependence and mechanism of the carrier. Biochem. J. 172, 377-387 PubMed
-
(1978)
Biochem. J.
, vol.172
, pp. 377-387
-
-
Halestrap, A.P.1
-
26
-
-
0016215681
-
Evidence for the role of a specific monocarboxylate transporter in the control of pyruvate oxidation by rat liver mitochondria
-
CrossRef PubMed
-
Mowbray, J. (1974) Evidence for the role of a specific monocarboxylate transporter in the control of pyruvate oxidation by rat liver mitochondria. FEBS Lett. 44, 344-347 CrossRef PubMed
-
(1974)
FEBS Lett.
, vol.44
, pp. 344-347
-
-
Mowbray, J.1
-
27
-
-
0016840797
-
Initial rates of pyruvate transport in mitochondria determined by an 'inhibitor-stop' technique
-
PubMed
-
Titheradge, M.A. and Coore, H.G. (1975) Initial rates of pyruvate transport in mitochondria determined by an 'inhibitor-stop' technique. Biochem. J. 150, 553-556 PubMed
-
(1975)
Biochem. J.
, vol.150
, pp. 553-556
-
-
Titheradge, M.A.1
Coore, H.G.2
-
28
-
-
0017280010
-
Substrate regulation of the pyruvate-transporting system in rat liver mitochondria
-
CrossRef PubMed
-
Paradies, G. and Papa, S. (1976) Substrate regulation of the pyruvate-transporting system in rat liver mitochondria. FEBS Lett. 62, 318-321 CrossRef PubMed
-
(1976)
FEBS Lett.
, vol.62
, pp. 318-321
-
-
Paradies, G.1
Papa, S.2
-
29
-
-
0017833712
-
Pyruvate and acetoacetate transport in mitochondria. A reappraisal
-
PubMed
-
Pande, S.V. and Parvin, R. (1978) Pyruvate and acetoacetate transport in mitochondria. A reappraisal. J. Biol. Chem. 253, 1565-1573 PubMed
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 1565-1573
-
-
Pande, S.V.1
Parvin, R.2
-
30
-
-
0022552209
-
Extraction, partial purification and functional reconstitution of two mitochondrial carriers transporting keto acids: 2-oxoglutarate and pyruvate
-
CrossRef PubMed
-
Nalecz, M.J., Nalecz, K.A., Broger, C., Bolli, R., Wojtczak, L. and Azzi, A. (1986) Extraction, partial purification and functional reconstitution of two mitochondrial carriers transporting keto acids: 2-oxoglutarate and pyruvate. FEBS Lett. 196, 331-336 CrossRef PubMed
-
(1986)
FEBS Lett.
, vol.196
, pp. 331-336
-
-
Nalecz, M.J.1
Nalecz, K.A.2
Broger, C.3
Bolli, R.4
Wojtczak, L.5
Azzi, A.6
-
31
-
-
0023048744
-
The extraction and reconstitution of the alpha-cyanocinnamate-sensitive pyruvate transporter from castor bean mitochondria
-
CrossRef PubMed
-
Brailsford, M.A., Thompson, A.G., Kaderbhai, N. and Beechey, R.B. (1986) The extraction and reconstitution of the alpha-cyanocinnamate-sensitive pyruvate transporter from castor bean mitochondria. Biochem. Biophys. Res. Commun. 140, 1036-1042 CrossRef PubMed
-
(1986)
Biochem. Biophys. Res. Commun.
, vol.140
, pp. 1036-1042
-
-
Brailsford, M.A.1
Thompson, A.G.2
Kaderbhai, N.3
Beechey, R.B.4
-
32
-
-
0025093378
-
The monocarboxylate carrier from rat liver mitochondria. Purification and kinetic characterization in a reconstituted system
-
CrossRef PubMed
-
Capuano, F., Di Paola, M., Azzi, A. and Papa, S. (1990) The monocarboxylate carrier from rat liver mitochondria. Purification and kinetic characterization in a reconstituted system. FEBS Lett. 261, 39-42 CrossRef PubMed
-
(1990)
FEBS Lett.
, vol.261
, pp. 39-42
-
-
Capuano, F.1
Di Paola, M.2
Azzi, A.3
Papa, S.4
-
33
-
-
0021774552
-
14C]cinnamate with the mitochondrial pyruvate translocator
-
CrossRef PubMed
-
14C]cinnamate with the mitochondrial pyruvate translocator. Biochim. Biophys. Acta 766, 446-450 CrossRef PubMed
-
(1984)
Biochim. Biophys. Acta
, vol.766
, pp. 446-450
-
-
Paradies, G.1
-
34
-
-
0022534328
-
Characterization of the alpha-cyanocinnamate binding site in rat heart mitochondria and in submitochondrial particles
-
CrossRef PubMed
-
Paradies, G. and Ruggiero, F.M. (1986) Characterization of the alpha-cyanocinnamate binding site in rat heart mitochondria and in submitochondrial particles. Biochim. Biophys. Acta 850, 249-255 CrossRef PubMed
-
(1986)
Biochim. Biophys. Acta
, vol.850
, pp. 249-255
-
-
Paradies, G.1
Ruggiero, F.M.2
-
35
-
-
0024441525
-
Monocarboxylate and alpha-ketoglutarate carriers from bovine heart mitochondria. Purification by affinity chromatography on immobilized 2-cyano-4-hydroxycinnamate
-
PubMed
-
Bolli, R., Nalecz, K.A. and Azzi, A. (1989) Monocarboxylate and alpha-ketoglutarate carriers from bovine heart mitochondria. Purification by affinity chromatography on immobilized 2-cyano-4-hydroxycinnamate. J. Biol. Chem. 264, 18024-18030 PubMed
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 18024-18030
-
-
Bolli, R.1
Nalecz, K.A.2
Azzi, A.3
-
36
-
-
0025887857
-
Purification and functional characterisation of the pyruvate (monocarboxylate) carrier from baker's yeast mitochondria (Saccharomyces cerevisiae)
-
CrossRef PubMed
-
Nalecz, M.J., Nalecz, K.A. and Azzi, A. (1991) Purification and functional characterisation of the pyruvate (monocarboxylate) carrier from baker's yeast mitochondria (Saccharomyces cerevisiae). Biochim. Biophys. Acta 1079, 87-95 CrossRef PubMed
-
(1991)
Biochim. Biophys. Acta
, vol.1079
, pp. 87-95
-
-
Nalecz, M.J.1
Nalecz, K.A.2
Azzi, A.3
-
37
-
-
0032724365
-
Cardiac and skeletal muscle mitochondria have a monocarboxylate transporter MCT1
-
PubMed
-
Brooks, G.A., Brown, M.A., Butz, C.E., Sicurello, J.P. and Dubouchaud, H. (1999) Cardiac and skeletal muscle mitochondria have a monocarboxylate transporter MCT1. J. Appl. Physiol. 87, 1713-1718 PubMed
-
(1999)
J. Appl. Physiol.
, vol.87
, pp. 1713-1718
-
-
Brooks, G.A.1
Brown, M.A.2
Butz, C.E.3
Sicurello, J.P.4
Dubouchaud, H.5
-
38
-
-
4344659155
-
MCT1 confirmed in rat striated muscle mitochondria
-
CrossRef PubMed
-
Butz, C.E., McClelland, G.B. and Brooks, G.A. (2004) MCT1 confirmed in rat striated muscle mitochondria. J. Appl. Physiol. 97, 1059-1066 CrossRef PubMed
-
(2004)
J. Appl. Physiol.
, vol.97
, pp. 1059-1066
-
-
Butz, C.E.1
McClelland, G.B.2
Brooks, G.A.3
-
39
-
-
33744931101
-
Colocalization of MCT1, CD147, and LDH in mitochondrial inner membrane of L6 muscle cells: Evidence of a mitochondrial lactate oxidation complex
-
CrossRef PubMed
-
Hashimoto, T., Hussien, R. and Brooks, G.A. (2006) Colocalization of MCT1, CD147, and LDH in mitochondrial inner membrane of L6 muscle cells: evidence of a mitochondrial lactate oxidation complex. Am. J. Physiol. Endocrinol. Metab. 290, E1237-E1244 CrossRef PubMed
-
(2006)
Am. J. Physiol. Endocrinol. Metab.
, vol.290
, pp. E1237-E1244
-
-
Hashimoto, T.1
Hussien, R.2
Brooks, G.A.3
-
41
-
-
0141791031
-
Identification of the mitochondrial pyruvate carrier in Saccharomyces cerevisiae
-
CrossRef PubMed
-
Hildyard, J.C. and Halestrap, A.P. (2003) Identification of the mitochondrial pyruvate carrier in Saccharomyces cerevisiae. Biochem. J. 374, 607-611 CrossRef PubMed
-
(2003)
Biochem. J.
, vol.374
, pp. 607-611
-
-
Hildyard, J.C.1
Halestrap, A.P.2
-
42
-
-
84883405503
-
Physiological and pathological roles of mitochondrial SLC25 carriers
-
CrossRef PubMed
-
Gutierrez-Aguilar, M. and Baines, C.P. (2013) Physiological and pathological roles of mitochondrial SLC25 carriers. Biochem. J. 454, 371-386 CrossRef PubMed
-
(2013)
Biochem. J.
, vol.454
, pp. 371-386
-
-
Gutierrez-Aguilar, M.1
Baines, C.P.2
-
43
-
-
84875218644
-
The mitochondrial transporter family SLC25: Identification, properties and physiopathology
-
CrossRef PubMed
-
Palmieri, F. (2013) The mitochondrial transporter family SLC25: identification, properties and physiopathology. Mol. Aspects Med. 34, 465-484 CrossRef PubMed
-
(2013)
Mol. Aspects Med.
, vol.34
, pp. 465-484
-
-
Palmieri, F.1
-
45
-
-
33748976734
-
Identification of mitochondrial carriers in Saccharomyces cerevisiae by transport assay of reconstituted recombinant proteins
-
CrossRef PubMed
-
Palmieri, F., Agrimi, G., Blanco, E., Castegna, A., Di Noia, M.A., Iacobazzi, V., Lasorsa, F.M., Marobbio, C.M., Palmieri, L., Scarcia, P. et al. (2006) Identification of mitochondrial carriers in Saccharomyces cerevisiae by transport assay of reconstituted recombinant proteins. Biochim. Biophys. Acta 1757, 1249-1262 CrossRef PubMed
-
(2006)
Biochim. Biophys. Acta
, vol.1757
, pp. 1249-1262
-
-
Palmieri, F.1
Agrimi, G.2
Blanco, E.3
Castegna, A.4
Di Noia, M.A.5
Iacobazzi, V.6
Lasorsa, F.M.7
Marobbio, C.M.8
Palmieri, L.9
Scarcia, P.10
-
46
-
-
84863552418
-
A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans
-
CrossRef PubMed
-
Bricker, D.K., Taylor, E.B., Schell, J.C., Orsak, T., Boutron, A., Chen, Y.C., Cox, J.E., Cardon, C.M., Van Vranken, J.G., Dephoure, N. et al. (2012) A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. Science 337, 96-100 CrossRef PubMed
-
(2012)
Science
, vol.337
, pp. 96-100
-
-
Bricker, D.K.1
Taylor, E.B.2
Schell, J.C.3
Orsak, T.4
Boutron, A.5
Chen, Y.C.6
Cox, J.E.7
Cardon, C.M.8
Van Vranken, J.G.9
Dephoure, N.10
-
47
-
-
84863553135
-
Identification and functional expression of the mitochondrial pyruvate carrier
-
CrossRef PubMed
-
Herzig, S., Raemy, E., Montessuit, S., Veuthey, J.L., Zamboni, N., Westermann, B., Kunji, E.R. and Martinou, J.C. (2012) Identification and functional expression of the mitochondrial pyruvate carrier. Science 337, 93-96 CrossRef PubMed
-
(2012)
Science
, vol.337
, pp. 93-96
-
-
Herzig, S.1
Raemy, E.2
Montessuit, S.3
Veuthey, J.L.4
Zamboni, N.5
Westermann, B.6
Kunji, E.R.7
Martinou, J.C.8
-
48
-
-
63849246525
-
Protein structure prediction on the Web: A case study using the Phyre server
-
CrossRef PubMed
-
Kelley, L.A. and Sternberg, M.J. (2009) Protein structure prediction on the Web: a case study using the Phyre server. Nat. Protoc. 4, 363-371 CrossRef PubMed
-
(2009)
Nat. Protoc.
, vol.4
, pp. 363-371
-
-
Kelley, L.A.1
Sternberg, M.J.2
-
49
-
-
84911473884
-
Structures of bacterial homologues of SWEET transporters in two distinct conformations
-
CrossRef PubMed
-
Xu, Y., Tao, Y., Cheung, L.S., Fan, C., Chen, L.Q., Xu, S., Perry, K., Frommer, W.B. and Feng, L. (2014) Structures of bacterial homologues of SWEET transporters in two distinct conformations. Nature 515, 448-452 CrossRef PubMed
-
(2014)
Nature
, vol.515
, pp. 448-452
-
-
Xu, Y.1
Tao, Y.2
Cheung, L.S.3
Fan, C.4
Chen, L.Q.5
Xu, S.6
Perry, K.7
Frommer, W.B.8
Feng, L.9
-
50
-
-
84918584476
-
Mitochondrial pyruvate import and its effects on homeostasis
-
PubMed
-
Vanderperre, B., Bender, T., Kunji, E.R. and Martinou, J.C. (2014) Mitochondrial pyruvate import and its effects on homeostasis. Curr. Opin. Cell Biol. 33C, 35-41 PubMed
-
(2014)
Curr. Opin. Cell Biol.
, vol.33 C
, pp. 35-41
-
-
Vanderperre, B.1
Bender, T.2
Kunji, E.R.3
Martinou, J.C.4
-
51
-
-
84896713080
-
Regulation of autophagy by cytosolic acetyl-coenzyme A
-
CrossRef PubMed
-
Marino, G., Pietrocola, F., Eisenberg, T., Kong, Y., Malik, S.A., Andryushkova, A., Schroeder, S., Pendl, T., Harger, A., Niso-Santano, M. et al. (2014) Regulation of autophagy by cytosolic acetyl-coenzyme A. Mol. Cell 53, 710-725 CrossRef PubMed
-
(2014)
Mol. Cell
, vol.53
, pp. 710-725
-
-
Marino, G.1
Pietrocola, F.2
Eisenberg, T.3
Kong, Y.4
Malik, S.A.5
Andryushkova, A.6
Schroeder, S.7
Pendl, T.8
Harger, A.9
Niso-Santano, M.10
-
52
-
-
84922468705
-
Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport
-
CrossRef PubMed
-
Yang, C., Ko, B., Hensley, C.T., Jiang, L., Wasti, A.T., Kim, J., Sudderth, J., Calvaruso, M.A., Lumata, L., Mitsche, M. et al. (2014) Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport. Mol. Cell 56, 414-424 CrossRef PubMed
-
(2014)
Mol. Cell
, vol.56
, pp. 414-424
-
-
Yang, C.1
Ko, B.2
Hensley, C.T.3
Jiang, L.4
Wasti, A.T.5
Kim, J.6
Sudderth, J.7
Calvaruso, M.A.8
Lumata, L.9
Mitsche, M.10
-
53
-
-
84922430730
-
Regulation of substrate utilization by the mitochondrial pyruvate carrier
-
CrossRef PubMed
-
Vacanti, N.M., Divakaruni, A.S., Green, C.R., Parker, S.J., Henry, R.R., Ciaraldi, T.P., Murphy, A.N. and Metallo, C.M. (2014) Regulation of substrate utilization by the mitochondrial pyruvate carrier. Mol. Cell 56, 425-435 CrossRef PubMed
-
(2014)
Mol. Cell
, vol.56
, pp. 425-435
-
-
Vacanti, N.M.1
Divakaruni, A.S.2
Green, C.R.3
Parker, S.J.4
Henry, R.R.5
Ciaraldi, T.P.6
Murphy, A.N.7
Metallo, C.M.8
-
54
-
-
84903390237
-
Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion
-
CrossRef PubMed
-
Vigueira, P.A., McCommis, K.S., Schweitzer, G.G., Remedi, M.S., Chambers, K.T., Fu, X., McDonald, W.G., Cole, S.L., Colca, J.R., Kletzien, R.F. et al. (2014) Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion. Cell Rep. 7, 2042-2053 CrossRef PubMed
-
(2014)
Cell Rep.
, vol.7
, pp. 2042-2053
-
-
Vigueira, P.A.1
McCommis, K.S.2
Schweitzer, G.G.3
Remedi, M.S.4
Chambers, K.T.5
Fu, X.6
McDonald, W.G.7
Cole, S.L.8
Colca, J.R.9
Kletzien, R.F.10
-
55
-
-
0031930319
-
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice
-
CrossRef PubMed
-
Larsson, N.G., Wang, J., Wilhelmsson, H., Oldfors, A., Rustin, P., Lewandoski, M., Barsh, G.S. and Clayton, D.A. (1998) Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat. Genet. 18, 231-236 CrossRef PubMed
-
(1998)
Nat. Genet.
, vol.18
, pp. 231-236
-
-
Larsson, N.G.1
Wang, J.2
Wilhelmsson, H.3
Oldfors, A.4
Rustin, P.5
Lewandoski, M.6
Barsh, G.S.7
Clayton, D.A.8
-
56
-
-
12244269954
-
Impaired mitochondrial pyruvate importation in a patient and a fetus at risk
-
CrossRef PubMed
-
Brivet, M., Garcia-Cazorla, A., Lyonnet, S., Dumez, Y., Nassogne, M.C., Slama, A., Boutron, A., Touati, G., Legrand, A. and Saudubray, J.M. (2003) Impaired mitochondrial pyruvate importation in a patient and a fetus at risk. Mol. Genet. Metab. 78, 186-192 CrossRef PubMed
-
(2003)
Mol. Genet. Metab.
, vol.78
, pp. 186-192
-
-
Brivet, M.1
Garcia-Cazorla, A.2
Lyonnet, S.3
Dumez, Y.4
Nassogne, M.C.5
Slama, A.6
Boutron, A.7
Touati, G.8
Legrand, A.9
Saudubray, J.M.10
-
57
-
-
84864655754
-
The mitochondrial pyruvate carrier: Has it been unearthed at last?
-
CrossRef PubMed
-
Halestrap, A.P. (2012) The mitochondrial pyruvate carrier: has it been unearthed at last? Cell Metab. 16, 141-143 CrossRef PubMed
-
(2012)
Cell Metab.
, vol.16
, pp. 141-143
-
-
Halestrap, A.P.1
-
58
-
-
84863539219
-
Cell biology. A mitochondrial mystery, solved
-
CrossRef PubMed
-
Divakaruni, A.S. and Murphy, A.N. (2012) Cell biology. A mitochondrial mystery, solved. Science 337, 41-43 CrossRef PubMed
-
(2012)
Science
, vol.337
, pp. 41-43
-
-
Divakaruni, A.S.1
Murphy, A.N.2
-
59
-
-
0001951257
-
Formation of oxaloacetate from pyruvate and carbon dioxide
-
PubMed
-
Utter, M.F. and Keech, D.B. (1960) Formation of oxaloacetate from pyruvate and carbon dioxide. J. Biol. Chem. 235, PC17-PC18 PubMed
-
(1960)
J. Biol. Chem.
, vol.235
, pp. PC17-PC18
-
-
Utter, M.F.1
Keech, D.B.2
-
60
-
-
0037163021
-
The key role of anaplerosis and cataplerosis for citric acid cycle function
-
CrossRef PubMed
-
Owen, O.E., Kalhan, S.C. and Hanson, R.W. (2002) The key role of anaplerosis and cataplerosis for citric acid cycle function. J. Biol. Chem. 277, 30409-30412 CrossRef PubMed
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30409-30412
-
-
Owen, O.E.1
Kalhan, S.C.2
Hanson, R.W.3
-
61
-
-
0014510986
-
Regulation of gluconeogenesis and lipogenesis. The regulation of mitochondrial pyruvate metabolism in guinea-pig liver synthesizing precursors for gluconeogenesis
-
PubMed
-
Somberg, E.W. and Mehlman, M.A. (1969) Regulation of gluconeogenesis and lipogenesis. The regulation of mitochondrial pyruvate metabolism in guinea-pig liver synthesizing precursors for gluconeogenesis. Biochem. J. 112, 435-447 PubMed
-
(1969)
Biochem. J.
, vol.112
, pp. 435-447
-
-
Somberg, E.W.1
Mehlman, M.A.2
-
62
-
-
0013782981
-
Paths of carbon in gluconeogenesis and lipogenesis: The role of mitochondria in supplying precursors of phosphoenolpyruvate
-
CrossRef PubMed
-
Lardy, H.A., Paetkau, V. and Walter, P. (1965) Paths of carbon in gluconeogenesis and lipogenesis: the role of mitochondria in supplying precursors of phosphoenolpyruvate. Proc. Natl. Acad. Sci. U.S.A. 53, 1410-1415 CrossRef PubMed
-
(1965)
Proc. Natl. Acad. Sci. U.S.A.
, vol.53
, pp. 1410-1415
-
-
Lardy, H.A.1
Paetkau, V.2
Walter, P.3
-
63
-
-
0027448813
-
The regulation of hepatic carbon flux by pyruvate dehydrogenase and pyruvate dehydrogenase kinase during long-term food restriction
-
PubMed
-
Sugden, M.C., Grimshaw, R.M. and Holness, M.J. (1993) The regulation of hepatic carbon flux by pyruvate dehydrogenase and pyruvate dehydrogenase kinase during long-term food restriction. Biochem. J. 296, 217-223 PubMed
-
(1993)
Biochem. J.
, vol.296
, pp. 217-223
-
-
Sugden, M.C.1
Grimshaw, R.M.2
Holness, M.J.3
-
65
-
-
0020094429
-
The regulation of the pyruvate dehydrogenase complex in the perfused rat liver: A role for the mitochondrial monocarboxylate translocator
-
CrossRef PubMed
-
Patel, T.B., Debuysere, M.S., Scholz, R. and Olson, M.S. (1982) The regulation of the pyruvate dehydrogenase complex in the perfused rat liver: a role for the mitochondrial monocarboxylate translocator. Arch. Biochem. Biophys. 213, 573-584 CrossRef PubMed
-
(1982)
Arch. Biochem. Biophys.
, vol.213
, pp. 573-584
-
-
Patel, T.B.1
Debuysere, M.S.2
Scholz, R.3
Olson, M.S.4
-
66
-
-
0023373305
-
Mitochondrial pyruvate carrier - A possible link between gluconeogenesis and ketogenesis in the liver
-
CrossRef PubMed
-
Kummel, L. (1987) Mitochondrial pyruvate carrier - a possible link between gluconeogenesis and ketogenesis in the liver. Biosci. Rep. 7, 593-597 CrossRef PubMed
-
(1987)
Biosci. Rep.
, vol.7
, pp. 593-597
-
-
Kummel, L.1
-
67
-
-
0020486588
-
Role of pyruvate transporter in the regulation of the pyruvate dehydrogenase multienzyme complex in perfused rat liver
-
CrossRef PubMed
-
Zwiebel, F.M., Schwabe, U., Olson, M.S. and Scholz, R. (1982) Role of pyruvate transporter in the regulation of the pyruvate dehydrogenase multienzyme complex in perfused rat liver. Biochemistry 21, 346-353 CrossRef PubMed
-
(1982)
Biochemistry
, vol.21
, pp. 346-353
-
-
Zwiebel, F.M.1
Schwabe, U.2
Olson, M.S.3
Scholz, R.4
-
68
-
-
0014670951
-
2 fixation by glucagon, epinephrine, and cortisol
-
PubMed
-
2 fixation by glucagon, epinephrine, and cortisol. J. Biol. Chem. 244, 6444-6450 PubMed
-
(1969)
J. Biol. Chem.
, vol.244
, pp. 6444-6450
-
-
Adam, P.A.1
Haynes, R.C.2
-
69
-
-
0020615217
-
Hormonal stimulation of gluconeogenesis through increased mitochondrial metabolic flux
-
PubMed
-
Martin, A.D. and Titheradge, M.A. (1983) Hormonal stimulation of gluconeogenesis through increased mitochondrial metabolic flux. Biochem. Soc. Trans. 11, 78-81 PubMed
-
(1983)
Biochem. Soc. Trans.
, vol.11
, pp. 78-81
-
-
Martin, A.D.1
Titheradge, M.A.2
-
70
-
-
0017233006
-
The mitochondrial pyruvate carrier, its exchange properties and its regulation by glucagon
-
CrossRef PubMed
-
Titheradge, M.A. and Coore, H.G. (1976) The mitochondrial pyruvate carrier, its exchange properties and its regulation by glucagon. FEBS Lett. 63, 45-50 CrossRef PubMed
-
(1976)
FEBS Lett.
, vol.63
, pp. 45-50
-
-
Titheradge, M.A.1
Coore, H.G.2
-
71
-
-
0017142056
-
Hormonal regulation of liver mitochondrial pyruvate carrier in relation to gluconeogenesis and lipogenesis
-
CrossRef PubMed
-
Titheradge, M.A. and Coore, H.G. (1976) Hormonal regulation of liver mitochondrial pyruvate carrier in relation to gluconeogenesis and lipogenesis. FEBS Lett. 72, 73-78 CrossRef PubMed
-
(1976)
FEBS Lett.
, vol.72
, pp. 73-78
-
-
Titheradge, M.A.1
Coore, H.G.2
-
72
-
-
0025283340
-
Streptozotocin-induced alterations in the levels of functional mitochondrial anion transport proteins
-
CrossRef PubMed
-
Kaplan, R.S., Oliveira, D.L. and Wilson, G.L. (1990) Streptozotocin-induced alterations in the levels of functional mitochondrial anion transport proteins. Arch. Biochem. Biophys. 280, 181-191 CrossRef PubMed
-
(1990)
Arch. Biochem. Biophys.
, vol.280
, pp. 181-191
-
-
Kaplan, R.S.1
Oliveira, D.L.2
Wilson, G.L.3
-
73
-
-
0025846931
-
The effect of insulin supplementation on diabetes-induced alterations in the extractable levels of functional mitochondrial anion transport proteins
-
CrossRef PubMed
-
Kaplan, R.S., Mayor, J.A., Blackwell, R., Maughon, R.H. and Wilson, G.L. (1991) The effect of insulin supplementation on diabetes-induced alterations in the extractable levels of functional mitochondrial anion transport proteins. Arch. Biochem. Biophys. 287, 305-311 CrossRef PubMed
-
(1991)
Arch. Biochem. Biophys.
, vol.287
, pp. 305-311
-
-
Kaplan, R.S.1
Mayor, J.A.2
Blackwell, R.3
Maughon, R.H.4
Wilson, G.L.5
-
74
-
-
0021722771
-
A re-evaluation of the role of mitochondrial pyruvate transport in the hormonal control of rat liver mitochondrial pyruvate metabolism
-
PubMed
-
Halestrap, A.P. and Armston, A.E. (1984) A re-evaluation of the role of mitochondrial pyruvate transport in the hormonal control of rat liver mitochondrial pyruvate metabolism. Biochem. J. 223, 677-685 PubMed
-
(1984)
Biochem. J.
, vol.223
, pp. 677-685
-
-
Halestrap, A.P.1
Armston, A.E.2
-
75
-
-
0022504641
-
The mechanism of the hormonal activation of respiration in isolated hepatocytes and its importance in the regulation of gluconeogenesis
-
PubMed
-
Quinlan, P.T. and Halestrap, A.P. (1986) The mechanism of the hormonal activation of respiration in isolated hepatocytes and its importance in the regulation of gluconeogenesis. Biochem. J. 236, 789-800 PubMed
-
(1986)
Biochem. J.
, vol.236
, pp. 789-800
-
-
Quinlan, P.T.1
Halestrap, A.P.2
-
76
-
-
0023656503
-
Evidence that the flux control coefficient of the respiratory chain is high during gluconeogenesis from lactate in hepatocytes from starved rats. Implications for the hormonal control of gluconeogenesis and action of hypoglycaemic agents
-
PubMed
-
Pryor, H.J., Smyth, J.E., Quinlan, P.T. and Halestrap, A.P. (1987) Evidence that the flux control coefficient of the respiratory chain is high during gluconeogenesis from lactate in hepatocytes from starved rats. Implications for the hormonal control of gluconeogenesis and action of hypoglycaemic agents. Biochem. J. 247, 449-457 PubMed
-
(1987)
Biochem. J.
, vol.247
, pp. 449-457
-
-
Pryor, H.J.1
Smyth, J.E.2
Quinlan, P.T.3
Halestrap, A.P.4
-
77
-
-
0017882107
-
Stimulation of pyruvate transport in metabolizing mitochondria through changes in the transmembrane pH gradient induced by glucagon treatment of rats
-
PubMed
-
Halestrap, A.P. (1978) Stimulation of pyruvate transport in metabolizing mitochondria through changes in the transmembrane pH gradient induced by glucagon treatment of rats. Biochem. J. 172, 389-398 PubMed
-
(1978)
Biochem. J.
, vol.172
, pp. 389-398
-
-
Halestrap, A.P.1
-
78
-
-
80655128616
-
Gene expression profile change and associated physiological and pathological effects in mouse liver induced by fasting and refeeding
-
CrossRef PubMed
-
Zhang, F., Xu, X., Zhou, B., He, Z. and Zhai, Q. (2011) Gene expression profile change and associated physiological and pathological effects in mouse liver induced by fasting and refeeding. PLoS ONE 6, e27553 CrossRef PubMed
-
(2011)
PLoS ONE
, vol.6
-
-
Zhang, F.1
Xu, X.2
Zhou, B.3
He, Z.4
Zhai, Q.5
-
79
-
-
84874561591
-
Gene expression profile analysis of type 2 diabetic mouse liver
-
CrossRef PubMed
-
Zhang, F., Xu, X., Zhang, Y., Zhou, B., He, Z. and Zhai, Q. (2013) Gene expression profile analysis of type 2 diabetic mouse liver. PLoS ONE 8, e57766 CrossRef PubMed
-
(2013)
PLoS ONE
, vol.8
-
-
Zhang, F.1
Xu, X.2
Zhang, Y.3
Zhou, B.4
He, Z.5
Zhai, Q.6
-
80
-
-
0014690263
-
Control of gluconeogenesis in liver. 3. Effects of L-lactate, pyruvate, fructose, glucagon, epinephrine, and adenosine 3′,5′-monophosphate on gluconeogenic intermediates in the perfused rat liver
-
PubMed
-
Exton, J.H. and Park, C.R. (1969) Control of gluconeogenesis in liver. 3. Effects of L-lactate, pyruvate, fructose, glucagon, epinephrine, and adenosine 3′,5′-monophosphate on gluconeogenic intermediates in the perfused rat liver. J. Biol. Chem. 244, 1424-1433 PubMed
-
(1969)
J. Biol. Chem.
, vol.244
, pp. 1424-1433
-
-
Exton, J.H.1
Park, C.R.2
-
81
-
-
0015325409
-
The effect of propionate on the metabolism of pyruvate and lactate in the perfused rat liver
-
PubMed
-
Chan, T.M. and Freedland, R.A. (1972) The effect of propionate on the metabolism of pyruvate and lactate in the perfused rat liver. Biochem. J. 127, 539-543 PubMed
-
(1972)
Biochem. J.
, vol.127
, pp. 539-543
-
-
Chan, T.M.1
Freedland, R.A.2
-
82
-
-
0019730897
-
The role of mitochondrial pyruvate transport in the stimulation by glucagon and phenylephrine of gluconeogenesis from L-lactate in isolated rat hepatocytes
-
PubMed
-
Thomas, A.P. and Halestrap, A.P. (1981) The role of mitochondrial pyruvate transport in the stimulation by glucagon and phenylephrine of gluconeogenesis from L-lactate in isolated rat hepatocytes. Biochem. J. 198, 551-560 PubMed
-
(1981)
Biochem. J.
, vol.198
, pp. 551-560
-
-
Thomas, A.P.1
Halestrap, A.P.2
-
83
-
-
0020994135
-
The role of mitochondrial pyruvate transport in the control of lactate gluconeogenesis
-
CrossRef PubMed
-
Rognstad, R. (1983) The role of mitochondrial pyruvate transport in the control of lactate gluconeogenesis. Int. J. Biochem. 15, 1417-1421 CrossRef PubMed
-
(1983)
Int. J. Biochem.
, vol.15
, pp. 1417-1421
-
-
Rognstad, R.1
-
84
-
-
33344470347
-
Metabolic effects of p-coumaric acid in the perfused rat liver
-
CrossRef PubMed
-
Lima, L.C., Buss, G.D., Ishii-Iwamoto, E.L., Salgueiro-Pagadigorria, C., Comar, J.F., Bracht, A. and Constantin, J. (2006) Metabolic effects of p-coumaric acid in the perfused rat liver. J. Biochem. Mol. Toxicol. 20, 18-26 CrossRef PubMed
-
(2006)
J. Biochem. Mol. Toxicol.
, vol.20
, pp. 18-26
-
-
Lima, L.C.1
Buss, G.D.2
Ishii-Iwamoto, E.L.3
Salgueiro-Pagadigorria, C.4
Comar, J.F.5
Bracht, A.6
Constantin, J.7
-
85
-
-
0023008536
-
Rate-limiting steps for hepatic gluconeogenesis. Mechanism of oxamate inhibition of mitochondrial pyruvate metabolism
-
PubMed
-
Martin-Requero, A., Ayuso, M.S. and Parrilla, R. (1986) Rate-limiting steps for hepatic gluconeogenesis. Mechanism of oxamate inhibition of mitochondrial pyruvate metabolism. J. Biol. Chem. 261, 13973-13978 PubMed
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 13973-13978
-
-
Martin-Requero, A.1
Ayuso, M.S.2
Parrilla, R.3
-
86
-
-
0018190321
-
Alanine metabolism in rat liver mitochondria
-
CrossRef PubMed
-
Dieterle, P., Brawand, F., Moser, U.K. and Walter, P. (1978) Alanine metabolism in rat liver mitochondria. Eur. J. Biochem. 88, 467-473 CrossRef PubMed
-
(1978)
Eur. J. Biochem.
, vol.88
, pp. 467-473
-
-
Dieterle, P.1
Brawand, F.2
Moser, U.K.3
Walter, P.4
-
87
-
-
33646779855
-
Minireview: Implication of mitochondria in insulin secretion and action
-
CrossRef PubMed
-
Wiederkehr, A. and Wollheim, C.B. (2006) Minireview: implication of mitochondria in insulin secretion and action. Endocrinology 147, 2643-2649 CrossRef PubMed
-
(2006)
Endocrinology
, vol.147
, pp. 2643-2649
-
-
Wiederkehr, A.1
Wollheim, C.B.2
-
88
-
-
0030810982
-
Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells
-
CrossRef PubMed
-
Schuit, F., De Vos, A., Farfari, S., Moens, K., Pipeleers, D., Brun, T. and Prentki, M. (1997) Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells. J. Biol. Chem. 272, 18572-18579 CrossRef PubMed
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18572-18579
-
-
Schuit, F.1
De Vos, A.2
Farfari, S.3
Moens, K.4
Pipeleers, D.5
Brun, T.6
Prentki, M.7
-
89
-
-
12044255619
-
Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing
-
PubMed
-
Sekine, N., Cirulli, V., Regazzi, R., Brown, L.J., Gine, E., Tamarit-Rodriguez, J., Girotti, M., Marie, S., MacDonald, M.J., Wollheim, C.B. et al. (1994) Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing. J. Biol. Chem. 269, 4895-4902 PubMed
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 4895-4902
-
-
Sekine, N.1
Cirulli, V.2
Regazzi, R.3
Brown, L.J.4
Gine, E.5
Tamarit-Rodriguez, J.6
Girotti, M.7
Marie, S.8
MacDonald, M.J.9
Wollheim, C.B.10
-
90
-
-
77953429949
-
Identification of genes selectively disallowed in the pancreatic islet
-
CrossRef PubMed
-
Pullen, T.J., Khan, A.M., Barton, G., Butcher, S.A., Sun, G. and Rutter, G.A. (2010) Identification of genes selectively disallowed in the pancreatic islet. Islets 2, 89-95 CrossRef PubMed
-
(2010)
Islets
, vol.2
, pp. 89-95
-
-
Pullen, T.J.1
Khan, A.M.2
Barton, G.3
Butcher, S.A.4
Sun, G.5
Rutter, G.A.6
-
91
-
-
0027686015
-
Glucose enters mitochondrial metabolism via both carboxylation and decarboxylation of pyruvate in pancreatic islets
-
CrossRef PubMed
-
MacDonald, M.J. (1993) Glucose enters mitochondrial metabolism via both carboxylation and decarboxylation of pyruvate in pancreatic islets. Metabolism 42, 1229-1231 CrossRef PubMed
-
(1993)
Metabolism
, vol.42
, pp. 1229-1231
-
-
MacDonald, M.J.1
-
92
-
-
11144262144
-
Perspective: Emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion
-
CrossRef PubMed
-
MacDonald, M.J., Fahien, L.A., Brown, L.J., Hasan, N.M., Buss, J.D. and Kendrick, M.A. (2005) Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion. Am. J. Physiol. Endocrinol. Metab. 288, E1-E15 CrossRef PubMed
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.288
, pp. E1-E15
-
-
MacDonald, M.J.1
Fahien, L.A.2
Brown, L.J.3
Hasan, N.M.4
Buss, J.D.5
Kendrick, M.A.6
-
93
-
-
57649118511
-
Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase
-
CrossRef PubMed
-
Hasan, N.M., Longacre, M.J., Stoker, S.W., Boonsaen, T., Jitrapakdee, S., Kendrick, M.A., Wallace, J.C. and MacDonald, M.J. (2008) Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase. J. Biol. Chem. 283, 28048-28059 CrossRef PubMed
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 28048-28059
-
-
Hasan, N.M.1
Longacre, M.J.2
Stoker, S.W.3
Boonsaen, T.4
Jitrapakdee, S.5
Kendrick, M.A.6
Wallace, J.C.7
MacDonald, M.J.8
-
94
-
-
53549112155
-
The role of pyruvate carboxylase in insulin secretion and proliferation in rat pancreatic beta cells
-
CrossRef PubMed
-
Xu, J., Han, J., Long, Y.S., Epstein, P.N. and Liu, Y.Q. (2008) The role of pyruvate carboxylase in insulin secretion and proliferation in rat pancreatic beta cells. Diabetologia 51, 2022-2030 CrossRef PubMed
-
(2008)
Diabetologia
, vol.51
, pp. 2022-2030
-
-
Xu, J.1
Han, J.2
Long, Y.S.3
Epstein, P.N.4
Liu, Y.Q.5
-
95
-
-
0037022527
-
13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)
-
CrossRef PubMed
-
13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS). Proc. Natl. Acad. Sci. U.S.A. 99, 2708-2713 CrossRef PubMed
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 2708-2713
-
-
Lu, D.1
Mulder, H.2
Zhao, P.3
Burgess, S.C.4
Jensen, M.V.5
Kamzolova, S.6
Newgard, C.B.7
Sherry, A.D.8
-
96
-
-
0036320906
-
K(ATP) channels and insulin secretion disorders
-
PubMed
-
Huopio, H., Shyng, S.L., Otonkoski, T. and Nichols, C.G. (2002) K(ATP) channels and insulin secretion disorders. Am. J. Physiol. Endocrinol. Metab. 283, E207-E216 PubMed
-
(2002)
Am. J. Physiol. Endocrinol. Metab.
, vol.283
, pp. E207-E216
-
-
Huopio, H.1
Shyng, S.L.2
Otonkoski, T.3
Nichols, C.G.4
-
97
-
-
78649665323
-
ss-Cell-specific pyruvate dehydrogenase deficiency impairs glucose-stimulated insulin secretion
-
CrossRef PubMed
-
Srinivasan, M., Choi, C.S., Ghoshal, P., Pliss, L., Pandya, J.D., Hill, D., Cline, G. and Patel, M.S. (2010) ss-Cell-specific pyruvate dehydrogenase deficiency impairs glucose-stimulated insulin secretion. Am. J. Physiol. Endocrinol. Metab. 299, E910-E917 CrossRef PubMed
-
(2010)
Am. J. Physiol. Endocrinol. Metab.
, vol.299
, pp. E910-E917
-
-
Srinivasan, M.1
Choi, C.S.2
Ghoshal, P.3
Pliss, L.4
Pandya, J.D.5
Hill, D.6
Cline, G.7
Patel, M.S.8
-
98
-
-
84907070978
-
Featured article: Beta cell specific pyruvate dehydrogenase alpha gene deletion results in a reduced islet number and beta-cell mass postnatally
-
CrossRef PubMed
-
Patel, M.S., Srinivasan, M., Strutt, B., Mahmood, S. and Hill, D.J. (2014) Featured article: beta cell specific pyruvate dehydrogenase alpha gene deletion results in a reduced islet number and beta-cell mass postnatally. Exp. Biol. Med. 239, 975-985 CrossRef PubMed
-
(2014)
Exp. Biol. Med.
, vol.239
, pp. 975-985
-
-
Patel, M.S.1
Srinivasan, M.2
Strutt, B.3
Mahmood, S.4
Hill, D.J.5
-
100
-
-
57349097780
-
Metabolic cycling in control of glucose-stimulated insulin secretion
-
CrossRef PubMed
-
Jensen, M.V., Joseph, J.W., Ronnebaum, S.M., Burgess, S.C., Sherry, A.D. and Newgard, C.B. (2008) Metabolic cycling in control of glucose-stimulated insulin secretion. Am. J. Physiol. Endocrinol. Metab. 295, E1287-E1297 CrossRef PubMed
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.295
, pp. E1287-E1297
-
-
Jensen, M.V.1
Joseph, J.W.2
Ronnebaum, S.M.3
Burgess, S.C.4
Sherry, A.D.5
Newgard, C.B.6
-
101
-
-
0032479342
-
Overexpression of lactate dehydrogenase A attenuates glucose-induced insulin secretion in stable MIN-6 beta-cell lines
-
CrossRef PubMed
-
Zhao, C. and Rutter, G.A. (1998) Overexpression of lactate dehydrogenase A attenuates glucose-induced insulin secretion in stable MIN-6 beta-cell lines. FEBS Lett. 430, 213-216 CrossRef PubMed
-
(1998)
FEBS Lett.
, vol.430
, pp. 213-216
-
-
Zhao, C.1
Rutter, G.A.2
-
102
-
-
0033919717
-
Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion
-
CrossRef PubMed
-
Ainscow, E.K., Zhao, C. and Rutter, G.A. (2000) Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion. Diabetes 49, 1149-1155 CrossRef PubMed
-
(2000)
Diabetes
, vol.49
, pp. 1149-1155
-
-
Ainscow, E.K.1
Zhao, C.2
Rutter, G.A.3
-
103
-
-
70450285188
-
Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion
-
CrossRef PubMed
-
Malmgren, S., Nicholls, D.G., Taneera, J., Bacos, K., Koeck, T., Tamaddon, A., Wibom, R., Groop, L., Ling, C., Mulder, H. et al. (2009) Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion. J. Biol. Chem. 284, 32395-32404 CrossRef PubMed
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 32395-32404
-
-
Malmgren, S.1
Nicholls, D.G.2
Taneera, J.3
Bacos, K.4
Koeck, T.5
Tamaddon, A.6
Wibom, R.7
Groop, L.8
Ling, C.9
Mulder, H.10
-
104
-
-
84899441075
-
Assessment of the metabolic pathways associated with glucose-stimulated biphasic insulin secretion
-
CrossRef PubMed
-
Huang, M. and Joseph, J.W. (2014) Assessment of the metabolic pathways associated with glucose-stimulated biphasic insulin secretion. Endocrinology 155, 1653-1666 CrossRef PubMed
-
(2014)
Endocrinology
, vol.155
, pp. 1653-1666
-
-
Huang, M.1
Joseph, J.W.2
-
105
-
-
84900459053
-
Mitochondrial metabolism of pyruvate is essential for regulating glucose-stimulated insulin secretion
-
CrossRef PubMed
-
Patterson, J.N., Cousteils, K., Lou, J.W., Manning Fox, J.E., Macdonald, P.E. and Joseph, J.W. (2014) Mitochondrial metabolism of pyruvate is essential for regulating glucose-stimulated insulin secretion. J. Biol. Chem. 289, 13335-13346 CrossRef PubMed
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 13335-13346
-
-
Patterson, J.N.1
Cousteils, K.2
Lou, J.W.3
Manning Fox, J.E.4
Macdonald, P.E.5
Joseph, J.W.6
-
106
-
-
0036459823
-
Contribution of glycolytic and mitochondrial pathways in glucose-induced changes in islet respiration and insulin secretion
-
CrossRef PubMed
-
Ortsater, H., Liss, P., Akerman, K.E. and Bergsten, P. (2002) Contribution of glycolytic and mitochondrial pathways in glucose-induced changes in islet respiration and insulin secretion. Pflugers Arch. 444, 506-512 CrossRef PubMed
-
(2002)
Pflugers Arch.
, vol.444
, pp. 506-512
-
-
Ortsater, H.1
Liss, P.2
Akerman, K.E.3
Bergsten, P.4
-
107
-
-
0029966507
-
Activation of stimulus-secretion coupling in pancreatic beta-cells by specific products of glucose metabolism. Evidence for privileged signaling by glycolysis
-
CrossRef PubMed
-
Mertz, R.J., Worley, J.F., Spencer, B., Johnson, J.H. and Dukes, I.D. (1996) Activation of stimulus-secretion coupling in pancreatic beta-cells by specific products of glucose metabolism. Evidence for privileged signaling by glycolysis. J. Biol. Chem. 271, 4838-4845 CrossRef PubMed
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4838-4845
-
-
Mertz, R.J.1
Worley, J.F.2
Spencer, B.3
Johnson, J.H.4
Dukes, I.D.5
-
108
-
-
0037163056
-
Pancreatic islet beta-cells transiently metabolize pyruvate
-
CrossRef PubMed
-
Rocheleau, J.V., Head, W.S., Nicholson, W.E., Powers, A.C. and Piston, D.W. (2002) Pancreatic islet beta-cells transiently metabolize pyruvate. J. Biol. Chem. 277,30914-30920 CrossRef PubMed
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30914-30920
-
-
Rocheleau, J.V.1
Head, W.S.2
Nicholson, W.E.3
Powers, A.C.4
Piston, D.W.5
-
109
-
-
84877057467
-
Novel insulin sensitizer modulates nutrient sensing pathways and maintains beta-cell phenotype in human islets
-
CrossRef PubMed
-
Rohatgi, N., Aly, H., Marshall, C.A., McDonald, W.G., Kletzien, R.F., Colca, J.R. and McDaniel, M.L. (2013) Novel insulin sensitizer modulates nutrient sensing pathways and maintains beta-cell phenotype in human islets. PLoS ONE 8, e62012 CrossRef PubMed
-
(2013)
PLoS ONE
, vol.8
-
-
Rohatgi, N.1
Aly, H.2
Marshall, C.A.3
McDonald, W.G.4
Kletzien, R.F.5
Colca, J.R.6
McDaniel, M.L.7
-
110
-
-
21244492310
-
Myocardial substrate metabolism in the normal and failing heart
-
CrossRef PubMed
-
Stanley, W.C., Recchia, F.A. and Lopaschuk, G.D. (2005) Myocardial substrate metabolism in the normal and failing heart. Physiol. Rev. 85, 1093-1129 CrossRef PubMed
-
(2005)
Physiol. Rev.
, vol.85
, pp. 1093-1129
-
-
Stanley, W.C.1
Recchia, F.A.2
Lopaschuk, G.D.3
-
111
-
-
0022352802
-
Metabolic fate of extracted glucose in normal human myocardium
-
CrossRef PubMed
-
Wisneski, J.A., Gertz, E.W., Neese, R.A., Gruenke, L.D., Morris, D.L. and Craig, J.C. (1985) Metabolic fate of extracted glucose in normal human myocardium. J. Clin. Invest. 76, 1819-1827 CrossRef PubMed
-
(1985)
J. Clin. Invest.
, vol.76
, pp. 1819-1827
-
-
Wisneski, J.A.1
Gertz, E.W.2
Neese, R.A.3
Gruenke, L.D.4
Morris, D.L.5
Craig, J.C.6
-
112
-
-
0026502463
-
Myocardial lactate extraction and release at rest and during heavy exercise in healthy men
-
CrossRef PubMed
-
Kaijser, L. and Berglund, B. (1992) Myocardial lactate extraction and release at rest and during heavy exercise in healthy men. Acta Physiol. Scand. 144, 39-45 CrossRef PubMed
-
(1992)
Acta Physiol. Scand.
, vol.144
, pp. 39-45
-
-
Kaijser, L.1
Berglund, B.2
-
113
-
-
0031036553
-
Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions
-
CrossRef PubMed
-
Stanley, W.C., Lopaschuk, G.D., Hall, J.L. and McCormack, J.G. (1997) Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions. Cardiovasc. Res. 33, 243-257 CrossRef PubMed
-
(1997)
Cardiovasc. Res.
, vol.33
, pp. 243-257
-
-
Stanley, W.C.1
Lopaschuk, G.D.2
Hall, J.L.3
McCormack, J.G.4
-
114
-
-
0025266282
-
Myocardial metabolism in insulin-deficient diabetic humans without coronary artery disease
-
PubMed
-
Avogaro, A., Nosadini, R., Doria, A., Fioretto, P., Velussi, M., Vigorito, C., Sacca, L., Toffolo, G., Cobelli, C., Trevisan, R. et al. (1990) Myocardial metabolism in insulin-deficient diabetic humans without coronary artery disease. Am. J. Physiol. 258, E606-E618 PubMed
-
(1990)
Am. J. Physiol.
, vol.258
, pp. E606-E618
-
-
Avogaro, A.1
Nosadini, R.2
Doria, A.3
Fioretto, P.4
Velussi, M.5
Vigorito, C.6
Sacca, L.7
Toffolo, G.8
Cobelli, C.9
Trevisan, R.10
-
115
-
-
0021674370
-
The concentration of the mitochondrial pyruvate carrier in rat liver and heart mitochondria determined with alpha-cyano-beta-(1-phenylindol-3-yl)acrylate
-
PubMed
-
Shearman, M.S. and Halestrap, A.P. (1984) The concentration of the mitochondrial pyruvate carrier in rat liver and heart mitochondria determined with alpha-cyano-beta-(1-phenylindol-3-yl)acrylate. Biochem. J. 223, 673-676 PubMed
-
(1984)
Biochem. J.
, vol.223
, pp. 673-676
-
-
Shearman, M.S.1
Halestrap, A.P.2
-
116
-
-
0023722050
-
Effect of hyperthyroidism on the transport of pyruvate in rat-heart mitochondria
-
CrossRef PubMed
-
Paradies, G. and Ruggiero, F.M. (1988) Effect of hyperthyroidism on the transport of pyruvate in rat-heart mitochondria. Biochim. Biophys. Acta 935, 79-86 CrossRef PubMed
-
(1988)
Biochim. Biophys. Acta
, vol.935
, pp. 79-86
-
-
Paradies, G.1
Ruggiero, F.M.2
-
117
-
-
0024502723
-
Decreased activity of the pyruvate translocator and changes in the lipid composition in heart mitochondria from hypothyroid rats
-
CrossRef PubMed
-
Paradies, G. and Ruggiero, F.M. (1989) Decreased activity of the pyruvate translocator and changes in the lipid composition in heart mitochondria from hypothyroid rats. Arch. Biochem. Biophys. 269, 595-602 CrossRef PubMed
-
(1989)
Arch. Biochem. Biophys.
, vol.269
, pp. 595-602
-
-
Paradies, G.1
Ruggiero, F.M.2
-
118
-
-
0025272543
-
Age-related changes in the activity of the pyruvate carrier and in the lipid composition in rat-heart mitochondria
-
CrossRef PubMed
-
Paradies, G. and Ruggiero, F.M. (1990) Age-related changes in the activity of the pyruvate carrier and in the lipid composition in rat-heart mitochondria. Biochim. Biophys. Acta 1016, 207-212 CrossRef PubMed
-
(1990)
Biochim. Biophys. Acta
, vol.1016
, pp. 207-212
-
-
Paradies, G.1
Ruggiero, F.M.2
-
119
-
-
0033012064
-
The effect of aging and acetyl-L-carnitine on the pyruvate transport and oxidation in rat heart mitochondria
-
CrossRef PubMed
-
Paradies, G., Petrosillo, G., Gadaleta, M.N. and Ruggiero, F.M. (1999) The effect of aging and acetyl-L-carnitine on the pyruvate transport and oxidation in rat heart mitochondria. FEBS Lett. 454, 207-209 CrossRef PubMed
-
(1999)
FEBS Lett.
, vol.454
, pp. 207-209
-
-
Paradies, G.1
Petrosillo, G.2
Gadaleta, M.N.3
Ruggiero, F.M.4
-
120
-
-
0027517206
-
Mitochondrial pyruvate transport in working guinea-pig heart. Work-related vs. carrier-mediated control of pyruvate oxidation
-
CrossRef PubMed
-
Bunger, R. and Mallet, R.T. (1993) Mitochondrial pyruvate transport in working guinea-pig heart. Work-related vs. carrier-mediated control of pyruvate oxidation. Biochim. Biophys. Acta 1151, 223-236 CrossRef PubMed
-
(1993)
Biochim. Biophys. Acta
, vol.1151
, pp. 223-236
-
-
Bunger, R.1
Mallet, R.T.2
-
121
-
-
0019543906
-
Alterations of carbohydrate and lipid metabolism in the acutely ischemic heart
-
CrossRef PubMed
-
Liedtke, A. J. (1981) Alterations of carbohydrate and lipid metabolism in the acutely ischemic heart. Prog. Cardiovasc. Dis. 23, 321-336 CrossRef PubMed
-
(1981)
Prog. Cardiovasc. Dis.
, vol.23
, pp. 321-336
-
-
Liedtke, A.J.1
-
122
-
-
0014540518
-
Sequential alterations in myocardial lactate metabolic S-T segments, and left ventricular function during angina induced by atrial pacing
-
CrossRef PubMed
-
Parker, J.O., Chiong, M.A., West, R.O. and Case, R.B. (1969) Sequential alterations in myocardial lactate metabolic S-T segments, and left ventricular function during angina induced by atrial pacing. Circulation 40, 113-131 CrossRef PubMed
-
(1969)
Circulation
, vol.40
, pp. 113-131
-
-
Parker, J.O.1
Chiong, M.A.2
West, R.O.3
Case, R.B.4
-
123
-
-
0028956370
-
Pyruvate dehydrogenase influences postischemic heart function
-
CrossRef PubMed
-
Lewandowski, E.D. and White, L.T. (1995) Pyruvate dehydrogenase influences postischemic heart function. Circulation 91, 2071-2079 CrossRef PubMed
-
(1995)
Circulation
, vol.91
, pp. 2071-2079
-
-
Lewandowski, E.D.1
White, L.T.2
-
124
-
-
21544445251
-
Metabolic cardioprotection by pyruvate: Recent progress
-
PubMed
-
Mallet, R.T., Sun, J., Knott, E.M., Sharma, A.B. and Olivencia-Yurvati, A.H. (2005) Metabolic cardioprotection by pyruvate: recent progress. Exp. Biol. Med. 230, 435-443 PubMed
-
(2005)
Exp. Biol. Med.
, vol.230
, pp. 435-443
-
-
Mallet, R.T.1
Sun, J.2
Knott, E.M.3
Sharma, A.B.4
Olivencia-Yurvati, A.H.5
-
125
-
-
0037125371
-
Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy
-
CrossRef PubMed
-
Davila-Roman, V.G., Vedala, G., Herrero, P., de las Fuentes, L., Rogers, J.G., Kelly, D.P. and Gropler, R.J. (2002) Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy. J. Am. Coll. Cardiol. 40, 271-277 CrossRef PubMed
-
(2002)
J. Am. Coll. Cardiol.
, vol.40
, pp. 271-277
-
-
Davila-Roman, V.G.1
Vedala, G.2
Herrero, P.3
De Las Fuentes, L.4
Rogers, J.G.5
Kelly, D.P.6
Gropler, R.J.7
-
126
-
-
0032539036
-
Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog
-
CrossRef PubMed
-
Recchia, F.A., McConnell, P.I., Bernstein, R.D., Vogel, T.R., Xu, X. and Hintze, T.H. (1998) Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog. Circ. Res. 83, 969-979 CrossRef PubMed
-
(1998)
Circ. Res.
, vol.83
, pp. 969-979
-
-
Recchia, F.A.1
McConnell, P.I.2
Bernstein, R.D.3
Vogel, T.R.4
Xu, X.5
Hintze, T.H.6
-
127
-
-
84872515091
-
Hyperpolarized (13)C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart
-
CrossRef PubMed
-
Schroeder, M.A., Lau, A.Z., Chen, A.P., Gu, Y., Nagendran, J., Barry, J., Hu, X., Dyck, J.R., Tyler, D.J., Clarke, K. et al. (2013) Hyperpolarized (13)C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart. Eur.J.HeartFail.15, 130-140 CrossRef PubMed
-
(2013)
Eur.J.HeartFail.
, vol.15
, pp. 130-140
-
-
Schroeder, M.A.1
Lau, A.Z.2
Chen, A.P.3
Gu, Y.4
Nagendran, J.5
Barry, J.6
Hu, X.7
Dyck, J.R.8
Tyler, D.J.9
Clarke, K.10
-
128
-
-
72949110566
-
Proteomic remodelling of mitochondrial oxidative pathways in pressure overload-induced heart failure
-
CrossRef PubMed
-
Bugger, H., Schwarzer, M., Chen, D., Schrepper, A., Amorim, P.A., Schoepe, M., Nguyen, T.D., Mohr, F.W., Khalimonchuk, O., Weimer, B.C. et al. (2010) Proteomic remodelling of mitochondrial oxidative pathways in pressure overload-induced heart failure. Cardiovasc. Res. 85, 376-384 CrossRef PubMed
-
(2010)
Cardiovasc. Res.
, vol.85
, pp. 376-384
-
-
Bugger, H.1
Schwarzer, M.2
Chen, D.3
Schrepper, A.4
Amorim, P.A.5
Schoepe, M.6
Nguyen, T.D.7
Mohr, F.W.8
Khalimonchuk, O.9
Weimer, B.C.10
-
129
-
-
39149096269
-
Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy
-
CrossRef PubMed
-
Zhao, G., Jeoung, N.H., Burgess, S.C., Rosaaen-Stowe, K.A., Inagaki, T., Latif, S., Shelton, J.M., McAnally, J., Bassel-Duby, R., Harris, R.A. et al. (2008) Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy. Am. J. Physiol. Heart Circ. Physiol. 294, H936-H943 CrossRef PubMed
-
(2008)
Am. J. Physiol. Heart Circ. Physiol.
, vol.294
, pp. H936-H943
-
-
Zhao, G.1
Jeoung, N.H.2
Burgess, S.C.3
Rosaaen-Stowe, K.A.4
Inagaki, T.5
Latif, S.6
Shelton, J.M.7
McAnally, J.8
Bassel-Duby, R.9
Harris, R.A.10
-
130
-
-
79958777022
-
Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: A combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study
-
CrossRef PubMed
-
Atherton, H.J., Dodd, M.S., Heather, L.C., Schroeder, M.A., Griffin, J.L., Radda, G.K., Clarke, K. and Tyler, D.J. (2011) Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study. Circulation 123, 2552-2561 CrossRef PubMed
-
(2011)
Circulation
, vol.123
, pp. 2552-2561
-
-
Atherton, H.J.1
Dodd, M.S.2
Heather, L.C.3
Schroeder, M.A.4
Griffin, J.L.5
Radda, G.K.6
Clarke, K.7
Tyler, D.J.8
-
131
-
-
11144354639
-
Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure
-
CrossRef PubMed
-
Lei, B., Lionetti, V., Young, M.E., Chandler, M.P., d'Agostino, C., Kang, E., Altarejos, M., Matsuo, K., Hintze, T. H., Stanley, W.C. et al. (2004) Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure. J. Mol. Cell. Cardiol. 36, 567-576 CrossRef PubMed
-
(2004)
J. Mol. Cell. Cardiol.
, vol.36
, pp. 567-576
-
-
Lei, B.1
Lionetti, V.2
Young, M.E.3
Chandler, M.P.4
D'Agostino, C.5
Kang, E.6
Altarejos, M.7
Matsuo, K.8
Hintze, T.H.9
Stanley, W.C.10
-
133
-
-
49249105457
-
Doxorubicin, cardiac risk factors, and cardiac toxicity in elderly patients with diffuse B-cell non-Hodgkin's lymphoma
-
CrossRef PubMed
-
Hershman, D.L., McBride, R.B., Eisenberger, A., Tsai, W.Y., Grann, V.R. and Jacobson, J.S. (2008) Doxorubicin, cardiac risk factors, and cardiac toxicity in elderly patients with diffuse B-cell non-Hodgkin's lymphoma. J. Clin. Oncol. 26, 3159-3165 CrossRef PubMed
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 3159-3165
-
-
Hershman, D.L.1
McBride, R.B.2
Eisenberger, A.3
Tsai, W.Y.4
Grann, V.R.5
Jacobson, J.S.6
-
134
-
-
27744491740
-
Activity of d,l-alpha-tocopherol (vitamin E) against cardiotoxicity induced by doxorubicin and doxorubicin with cyclophosphamide in mice
-
CrossRef PubMed
-
Bjelogrlic, S.K., Radic, J., Jovic, V. and Radulovic, S. (2005) Activity of d,l-alpha-tocopherol (vitamin E) against cardiotoxicity induced by doxorubicin and doxorubicin with cyclophosphamide in mice. Basic Clin. Pharmacol. Toxicol. 97, 311-319 CrossRef PubMed
-
(2005)
Basic Clin. Pharmacol. Toxicol.
, vol.97
, pp. 311-319
-
-
Bjelogrlic, S.K.1
Radic, J.2
Jovic, V.3
Radulovic, S.4
-
135
-
-
77950020340
-
Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy
-
CrossRef PubMed
-
Carvalho, R.A., Sousa, R.P., Cadete, V.J., Lopaschuk, G.D., Palmeira, C.M., Bjork, J.A. and Wallace, K.B. (2010) Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy. Toxicology 270, 92-98 CrossRef PubMed
-
(2010)
Toxicology
, vol.270
, pp. 92-98
-
-
Carvalho, R.A.1
Sousa, R.P.2
Cadete, V.J.3
Lopaschuk, G.D.4
Palmeira, C.M.5
Bjork, J.A.6
Wallace, K.B.7
-
136
-
-
0023481968
-
Hepatic and cardiac carnitine palmitoyltransferase activity. Effects of Adriamycin and galactosamine
-
CrossRef PubMed
-
Brady, L.J. and Brady, P.S. (1987) Hepatic and cardiac carnitine palmitoyltransferase activity. Effects of Adriamycin and galactosamine. Biochem. Pharmacol. 36, 3419-3423 CrossRef PubMed
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 3419-3423
-
-
Brady, L.J.1
Brady, P.S.2
-
137
-
-
0031080688
-
Acute and chronic effects of Adriamycin on fatty acid oxidation in isolated cardiac myocytes
-
CrossRef PubMed
-
Abdel-aleem, S., el-Merzabani, M.M., Sayed-Ahmed, M., Taylor, D.A. and Lowe, J.E. (1997) Acute and chronic effects of Adriamycin on fatty acid oxidation in isolated cardiac myocytes. J. Mol. Cell. Cardiol. 29, 789-797 CrossRef PubMed
-
(1997)
J. Mol. Cell. Cardiol.
, vol.29
, pp. 789-797
-
-
Abdel-aleem, S.1
El-Merzabani, M.M.2
Sayed-Ahmed, M.3
Taylor, D.A.4
Lowe, J.E.5
-
138
-
-
0018746850
-
The physiological role of pyruvate carboxylation in hamster brown adipose tissue
-
CrossRef PubMed
-
Cannon, B. and Nedergaard, J. (1979) The physiological role of pyruvate carboxylation in hamster brown adipose tissue. Eur. J. Biochem. 94, 419-426 CrossRef PubMed
-
(1979)
Eur. J. Biochem.
, vol.94
, pp. 419-426
-
-
Cannon, B.1
Nedergaard, J.2
-
139
-
-
84863609131
-
Insulin resistance and metabolic derangements in obese mice are ameliorated by a novel peroxisome proliferator-activated receptor gamma-sparing thiazolidinedione
-
CrossRef PubMed
-
Chen, Z., Vigueira, P.A., Chambers, K.T., Hall, A.M., Mitra, M.S., Qi, N., McDonald, W.G., Colca, J.R., Kletzien, R.F. and Finck, B.N. (2012) Insulin resistance and metabolic derangements in obese mice are ameliorated by a novel peroxisome proliferator-activated receptor gamma-sparing thiazolidinedione. J. Biol. Chem. 287, 23537-23548 CrossRef PubMed
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 23537-23548
-
-
Chen, Z.1
Vigueira, P.A.2
Chambers, K.T.3
Hall, A.M.4
Mitra, M.S.5
Qi, N.6
McDonald, W.G.7
Colca, J.R.8
Kletzien, R.F.9
Finck, B.N.10
-
140
-
-
84907485620
-
Browning of white adipose cells by intermediate metabolites: An adaptive mechanism to alleviate redox pressure
-
PubMed
-
Carriere, A., Jeanson, Y., Berger-Muller, S., Andre, M., Chenouard, V., Arnaud, E., Barreau, C., Walther, R., Galinier, A., Wdziekonski, B. et al. (2014) Browning of white adipose cells by intermediate metabolites: an adaptive mechanism to alleviate redox pressure. Diabetes 63, 3253-3265 PubMed
-
(2014)
Diabetes
, vol.63
, pp. 3253-3265
-
-
Carriere, A.1
Jeanson, Y.2
Berger-Muller, S.3
Andre, M.4
Chenouard, V.5
Arnaud, E.6
Barreau, C.7
Walther, R.8
Galinier, A.9
Wdziekonski, B.10
-
141
-
-
84865993166
-
Cellular links between neuronal activity and energy homeostasis
-
CrossRef PubMed
-
Shetty, P.K., Galeffi, F. and Turner, D.A. (2012) Cellular links between neuronal activity and energy homeostasis. Front. Pharmacol. 3, 43CrossRef PubMed
-
(2012)
Front. Pharmacol.
, vol.3
, pp. 43
-
-
Shetty, P.K.1
Galeffi, F.2
Turner, D.A.3
-
142
-
-
84875235160
-
Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease
-
CrossRef PubMed
-
Zilberter, M., Ivanov, A., Ziyatdinova, S., Mukhtarov, M., Malkov, A., Alpar, A., Tortoriello, G., Botting, C.H., Fulop, L., Osypov, A.A. et al. (2013) Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease. J. Neurochem. 125, 157-171 CrossRef PubMed
-
(2013)
J. Neurochem.
, vol.125
, pp. 157-171
-
-
Zilberter, M.1
Ivanov, A.2
Ziyatdinova, S.3
Mukhtarov, M.4
Malkov, A.5
Alpar, A.6
Tortoriello, G.7
Botting, C.H.8
Fulop, L.9
Osypov, A.A.10
-
143
-
-
0021813419
-
An immunochemical study of the pyruvate dehydrogenase deficit in Alzheimer's disease brain
-
CrossRef PubMed
-
Sheu, K.F., Kim, Y.T., Blass, J.P. and Weksler, M.E. (1985) An immunochemical study of the pyruvate dehydrogenase deficit in Alzheimer's disease brain. Ann. Neurol. 17, 444-449 CrossRef PubMed
-
(1985)
Ann. Neurol.
, vol.17
, pp. 444-449
-
-
Sheu, K.F.1
Kim, Y.T.2
Blass, J.P.3
Weksler, M.E.4
-
144
-
-
0020685951
-
Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain
-
CrossRef PubMed
-
Sorbi, S., Bird, E.D. and Blass, J.P. (1983) Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain. Ann. Neurol. 13, 72-78 CrossRef PubMed
-
(1983)
Ann. Neurol.
, vol.13
, pp. 72-78
-
-
Sorbi, S.1
Bird, E.D.2
Blass, J.P.3
-
145
-
-
0028784936
-
Increased cerebrospinal fluid pyruvate levels in Alzheimer's disease
-
CrossRef PubMed
-
Parnetti, L., Gaiti, A., Polidori, M.C., Brunetti, M., Palumbo, B., Chionne, F., Cadini, D., Cecchetti, R. and Senin, U. (1995) Increased cerebrospinal fluid pyruvate levels in Alzheimer's disease. Neurosci. Lett. 199, 231-233 CrossRef PubMed
-
(1995)
Neurosci. Lett.
, vol.199
, pp. 231-233
-
-
Parnetti, L.1
Gaiti, A.2
Polidori, M.C.3
Brunetti, M.4
Palumbo, B.5
Chionne, F.6
Cadini, D.7
Cecchetti, R.8
Senin, U.9
-
146
-
-
68949110561
-
Metabolic profiling of Parkinson's disease: Evidence of biomarker from gene expression analysis and rapid neural network detection
-
CrossRef PubMed
-
Ahmed, S.S., Santosh, W., Kumar, S. and Christlet, H.T. (2009) Metabolic profiling of Parkinson's disease: evidence of biomarker from gene expression analysis and rapid neural network detection. J. Biomed. Sci. 16, 63CrossRef PubMed
-
(2009)
J. Biomed. Sci.
, vol.16
, pp. 63
-
-
Ahmed, S.S.1
Santosh, W.2
Kumar, S.3
Christlet, H.T.4
-
147
-
-
0016259467
-
Inhibition of mitochondrial pyruvate transport by phenylpyruvate and alpha-ketoisocaproate
-
CrossRef PubMed
-
Halestrap, A.P., Brand, M.D. and Denton, R.M. (1974) Inhibition of mitochondrial pyruvate transport by phenylpyruvate and alpha-ketoisocaproate. Biochim. Biophys. Acta 367, 102-108 CrossRef PubMed
-
(1974)
Biochim. Biophys. Acta
, vol.367
, pp. 102-108
-
-
Halestrap, A.P.1
Brand, M.D.2
Denton, R.M.3
-
148
-
-
0018931252
-
The utilization of choline and acetyl coenzyme A for the synthesis of acetylcholine
-
CrossRef PubMed
-
Jope, R.S. and Jenden, D.J. (1980) The utilization of choline and acetyl coenzyme A for the synthesis of acetylcholine. J. Neurochem. 35, 318-325 CrossRef PubMed
-
(1980)
J. Neurochem.
, vol.35
, pp. 318-325
-
-
Jope, R.S.1
Jenden, D.J.2
-
149
-
-
0019972810
-
The cholinergic hypothesis of geriatric memory dysfunction
-
CrossRef PubMed
-
Bartus, R.T., Dean, 3rd, R.L., Beer, B. and Lippa, A.S. (1982) The cholinergic hypothesis of geriatric memory dysfunction. Science 217, 408-414 CrossRef PubMed
-
(1982)
Science
, vol.217
, pp. 408-414
-
-
Bartus, R.T.1
Dean, R.L.2
Beer, B.3
Lippa, A.S.4
-
150
-
-
85006768050
-
The metabolism of tumors in the body
-
CrossRef PubMed
-
Warburg, O., Wind, F. and Negelein, E. (1927) The metabolism of tumors in the body. J. Gen. Physiol. 8, 519-530 CrossRef PubMed
-
(1927)
J. Gen. Physiol.
, vol.8
, pp. 519-530
-
-
Warburg, O.1
Wind, F.2
Negelein, E.3
-
151
-
-
84255162057
-
Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism
-
CrossRef PubMed
-
Hitosugi, T., Fan, J., Chung, T.W., Lythgoe, K., Wang, X., Xie, J., Ge, Q., Gu, T.L., Polakiewicz, R.D., Roesel, J.L. et al. (2011) Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism. Mol. Cell 44, 864-877 CrossRef PubMed
-
(2011)
Mol. Cell
, vol.44
, pp. 864-877
-
-
Hitosugi, T.1
Fan, J.2
Chung, T.W.3
Lythgoe, K.4
Wang, X.5
Xie, J.6
Ge, Q.7
Gu, T.L.8
Polakiewicz, R.D.9
Roesel, J.L.10
-
152
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
CrossRef PubMed
-
Christofk, H.R., Vander Heiden, M.G., Harris, M.H., Ramanathan, A., Gerszten, R.E., Wei, R., Fleming, M.D., Schreiber, S.L. and Cantley, L.C. (2008) The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 452, 230-233 CrossRef PubMed
-
(2008)
Nature
, vol.452
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
Fleming, M.D.7
Schreiber, S.L.8
Cantley, L.C.9
-
153
-
-
0017364394
-
Pyruvate transport in tumour-cell mitochondria
-
CrossRef PubMed
-
Eboli, M.L., Paradies, G., Galeotti, T. and Papa, S. (1977) Pyruvate transport in tumour-cell mitochondria. Biochim. Biophys. Acta 460, 183-187 CrossRef PubMed
-
(1977)
Biochim. Biophys. Acta
, vol.460
, pp. 183-187
-
-
Eboli, M.L.1
Paradies, G.2
Galeotti, T.3
Papa, S.4
-
154
-
-
0021039988
-
Transport of pyruvate in mitochondria from different tumor cells
-
PubMed
-
Paradies, G., Capuano, F., Palombini, G., Galeotti, T. and Papa, S. (1983) Transport of pyruvate in mitochondria from different tumor cells. Cancer Res. 43, 5068-5071 PubMed
-
(1983)
Cancer Res.
, vol.43
, pp. 5068-5071
-
-
Paradies, G.1
Capuano, F.2
Palombini, G.3
Galeotti, T.4
Papa, S.5
-
155
-
-
84922445353
-
A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth
-
CrossRef PubMed
-
Schell, J.C., Olson, K.A., Jiang, L., Hawkins, A.J., Van Vranken, J.G., Xie, J., Egnatchik, R.A., Earl, E.G., DeBerardinis, R.J. and Rutter, J. (2014) A role for the mitochondrial pyruvate carrier as a repressor of the Warburg effect and colon cancer cell growth. Mol. Cell 56, 400-413 CrossRef PubMed
-
(2014)
Mol. Cell
, vol.56
, pp. 400-413
-
-
Schell, J.C.1
Olson, K.A.2
Jiang, L.3
Hawkins, A.J.4
Van Vranken, J.G.5
Xie, J.6
Egnatchik, R.A.7
Earl, E.G.8
DeBerardinis, R.J.9
Rutter, J.10
-
156
-
-
84896140152
-
The long and winding road to the mitochondrial pyruvate carrier
-
PubMed
-
Schell, J.C. and Rutter, J. (2013) The long and winding road to the mitochondrial pyruvate carrier. Cancer Metab. 1, 6 PubMed
-
(2013)
Cancer Metab.
, vol.1
, pp. 6
-
-
Schell, J.C.1
Rutter, J.2
|