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Volumn 6, Issue 11, 2011, Pages

Gene expression profile change and associated physiological and pathological effects in mouse liver induced by fasting and refeeding

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOXYLIC ACID METABOLISM; CONTROLLED STUDY; DIABETES MELLITUS; DIET RESTRICTION; FATTY ACID METABOLISM; FOOD AVAILABILITY; GENE CLUSTER; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE MAPPING; GENE REGULATORY NETWORK; GENETIC ASSOCIATION; HEPATITIS; HEPATITIS C; HIGH THROUGHPUT SEQUENCING; LIPID METABOLISM; LIVER CANCER; LIVER CIRRHOSIS; LIVER DISEASE; LIVER FUNCTION; LIVER METABOLISM; LIVER TUMOR; METABOLISM; MOUSE; NONHUMAN; REFEEDING; ANIMAL; C57BL MOUSE; LIVER; MALE; METHODOLOGY; PHYSIOLOGY;

EID: 80655128616     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027553     Document Type: Article
Times cited : (48)

References (54)
  • 1
    • 70350087752 scopus 로고    scopus 로고
    • Preventing diet induced disease: bioavailable nutrient-rich, low-energy-dense diets
    • Robson AA, (2009) Preventing diet induced disease: bioavailable nutrient-rich, low-energy-dense diets. Nutr Health 20: 135-166.
    • (2009) Nutr Health , vol.20 , pp. 135-166
    • Robson, A.A.1
  • 2
    • 33645456344 scopus 로고
    • The residues of malnutrition and starvation
    • Keys A, (1950) The residues of malnutrition and starvation. Science 112: 371-373.
    • (1950) Science , vol.112 , pp. 371-373
    • Keys, A.1
  • 3
    • 0026496482 scopus 로고
    • Schizophrenia after prenatal exposure to the Dutch Hunger Winter of 1944-1945
    • Susser ES, Lin SP, (1992) Schizophrenia after prenatal exposure to the Dutch Hunger Winter of 1944-1945. Arch Gen Psychiatry 49: 983-988.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 983-988
    • Susser, E.S.1    Lin, S.P.2
  • 4
    • 23044493965 scopus 로고    scopus 로고
    • Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961
    • St Clair D, Xu M, Wang P, Yu Y, Fang Y, et al. (2005) Rates of adult schizophrenia following prenatal exposure to the Chinese famine of 1959-1961. Jama 294: 557-562.
    • (2005) Jama , vol.294 , pp. 557-562
    • St Clair, D.1    Xu, M.2    Wang, P.3    Yu, Y.4    Fang, Y.5
  • 5
    • 34247390126 scopus 로고    scopus 로고
    • Fasting - the ultimate diet?
    • Johnstone AM, (2007) Fasting- the ultimate diet? Obes Rev 8: 211-222.
    • (2007) Obes Rev , vol.8 , pp. 211-222
    • Johnstone, A.M.1
  • 7
    • 0028353666 scopus 로고
    • Predictors of weight change over two years among a population of working adults: the Healthy Worker Project
    • French SA, Jeffery RW, Forster JL, McGovern PG, Kelder SH, et al. (1994) Predictors of weight change over two years among a population of working adults: the Healthy Worker Project. Int J Obes Relat Metab Disord 18: 145-154.
    • (1994) Int J Obes Relat Metab Disord , vol.18 , pp. 145-154
    • French, S.A.1    Jeffery, R.W.2    Forster, J.L.3    McGovern, P.G.4    Kelder, S.H.5
  • 8
    • 72949085739 scopus 로고    scopus 로고
    • Ageing: Diet and longevity in the balance
    • Flatt T, (2009) Ageing: Diet and longevity in the balance. Nature 462: 989-990.
    • (2009) Nature , vol.462 , pp. 989-990
    • Flatt, T.1
  • 9
    • 0141720388 scopus 로고    scopus 로고
    • Calorie restriction and aging: review of the literature and implications for studies in humans
    • Heilbronn LK, Ravussin E, (2003) Calorie restriction and aging: review of the literature and implications for studies in humans. Am J Clin Nutr 78: 361-369.
    • (2003) Am J Clin Nutr , vol.78 , pp. 361-369
    • Heilbronn, L.K.1    Ravussin, E.2
  • 10
    • 34447288233 scopus 로고    scopus 로고
    • Alternate-day fasting and chronic disease prevention: a review of human and animal trials
    • Varady KA, Hellerstein MK, (2007) Alternate-day fasting and chronic disease prevention: a review of human and animal trials. Am J Clin Nutr 86: 7-13.
    • (2007) Am J Clin Nutr , vol.86 , pp. 7-13
    • Varady, K.A.1    Hellerstein, M.K.2
  • 11
    • 0017808632 scopus 로고
    • Liver disease and nutrition
    • Mezey E, (1978) Liver disease and nutrition. Gastroenterology 74: 770-783.
    • (1978) Gastroenterology , vol.74 , pp. 770-783
    • Mezey, E.1
  • 12
    • 43449094044 scopus 로고    scopus 로고
    • Using genomic biology to study liver metabolism
    • Swanson KS, (2008) Using genomic biology to study liver metabolism. J Anim Physiol Anim Nutr (Berl) 92: 246-252.
    • (2008) J Anim Physiol Anim Nutr (Berl) , vol.92 , pp. 246-252
    • Swanson, K.S.1
  • 13
    • 0033594980 scopus 로고    scopus 로고
    • A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders
    • Leone TC, Weinheimer CJ, Kelly DP, (1999) A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders. Proc Natl Acad Sci U S A 96: 7473-7478.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7473-7478
    • Leone, T.C.1    Weinheimer, C.J.2    Kelly, D.P.3
  • 14
    • 0026520193 scopus 로고
    • Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis
    • Pilkis SJ, Granner DK, (1992) Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis. Annu Rev Physiol 54: 885-909.
    • (1992) Annu Rev Physiol , vol.54 , pp. 885-909
    • Pilkis, S.J.1    Granner, D.K.2
  • 15
    • 0032699670 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting
    • Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, et al. (1999) Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J Clin Invest 103: 1489-1498.
    • (1999) J Clin Invest , vol.103 , pp. 1489-1498
    • Kersten, S.1    Seydoux, J.2    Peters, J.M.3    Gonzalez, F.J.4    Desvergne, B.5
  • 16
    • 0032489437 scopus 로고    scopus 로고
    • Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha)
    • Aoyama T, Peters JM, Iritani N, Nakajima T, Furihata K, et al. (1998) Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha). J Biol Chem 273: 5678-5684.
    • (1998) J Biol Chem , vol.273 , pp. 5678-5684
    • Aoyama, T.1    Peters, J.M.2    Iritani, N.3    Nakajima, T.4    Furihata, K.5
  • 17
    • 28444483953 scopus 로고    scopus 로고
    • Insulin regulation of PEPCK gene expression: a model for rapid and reversible modulation
    • Quinn PG, Yeagley D, (2005) Insulin regulation of PEPCK gene expression: a model for rapid and reversible modulation. Curr Drug Targets Immune Endocr Metabol Disord 5: 423-437.
    • (2005) Curr Drug Targets Immune Endocr Metabol Disord , vol.5 , pp. 423-437
    • Quinn, P.G.1    Yeagley, D.2
  • 18
    • 0035855858 scopus 로고    scopus 로고
    • Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
    • Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, et al. (2001) Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 413: 131-138.
    • (2001) Nature , vol.413 , pp. 131-138
    • Yoon, J.C.1    Puigserver, P.2    Chen, G.3    Donovan, J.4    Wu, Z.5
  • 19
    • 14544282413 scopus 로고    scopus 로고
    • Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
    • Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, et al. (2005) Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434: 113-118.
    • (2005) Nature , vol.434 , pp. 113-118
    • Rodgers, J.T.1    Lerin, C.2    Haas, W.3    Gygi, S.P.4    Spiegelman, B.M.5
  • 20
    • 27144471700 scopus 로고    scopus 로고
    • Impact of microarray technology in nutrition and food research
    • Spielbauer B, Stahl F, (2005) Impact of microarray technology in nutrition and food research. Mol Nutr Food Res 49: 908-917.
    • (2005) Mol Nutr Food Res , vol.49 , pp. 908-917
    • Spielbauer, B.1    Stahl, F.2
  • 21
    • 0035845492 scopus 로고    scopus 로고
    • Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice
    • Cao SX, Dhahbi JM, Mote PL, Spindler SR, (2001) Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice. Proc Natl Acad Sci U S A 98: 10630-10635.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10630-10635
    • Cao, S.X.1    Dhahbi, J.M.2    Mote, P.L.3    Spindler, S.R.4
  • 22
    • 3843070757 scopus 로고    scopus 로고
    • Starvation response in mouse liver shows strong correlation with life-span-prolonging processes
    • Bauer M, Hamm AC, Bonaus M, Jacob A, Jaekel J, et al. (2004) Starvation response in mouse liver shows strong correlation with life-span-prolonging processes. Physiol Genomics 17: 230-244.
    • (2004) Physiol Genomics , vol.17 , pp. 230-244
    • Bauer, M.1    Hamm, A.C.2    Bonaus, M.3    Jacob, A.4    Jaekel, J.5
  • 23
    • 59449098993 scopus 로고    scopus 로고
    • Transcriptome profiling of the feeding-to-fasting transition in chicken liver
    • Desert C, Duclos MJ, Blavy P, Lecerf F, Moreews F, et al. (2008) Transcriptome profiling of the feeding-to-fasting transition in chicken liver. BMC Genomics 9: 611.
    • (2008) BMC Genomics , vol.9 , pp. 611
    • Desert, C.1    Duclos, M.J.2    Blavy, P.3    Lecerf, F.4    Moreews, F.5
  • 24
    • 57149085481 scopus 로고    scopus 로고
    • Deep sequencing-based expression analysis shows major advances in robustness, resolution and inter-lab portability over five microarray platforms
    • t Hoen PA, Ariyurek Y, Thygesen HH, Vreugdenhil E, Vossen RH, et al. (2008) Deep sequencing-based expression analysis shows major advances in robustness, resolution and inter-lab portability over five microarray platforms. Nucleic Acids Res 36: e141.
    • (2008) Nucleic Acids Res , vol.36
    • t Hoen, P.A.1    Ariyurek, Y.2    Thygesen, H.H.3    Vreugdenhil, E.4    Vossen, R.H.5
  • 25
    • 50649089207 scopus 로고    scopus 로고
    • RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays
    • Marioni JC, Mason CE, Mane SM, Stephens M, Gilad Y, (2008) RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays. Genome Res 18: 1509-1517.
    • (2008) Genome Res , vol.18 , pp. 1509-1517
    • Marioni, J.C.1    Mason, C.E.2    Mane, S.M.3    Stephens, M.4    Gilad, Y.5
  • 26
    • 67149098194 scopus 로고    scopus 로고
    • Current-generation high-throughput sequencing: deepening insights into mammalian transcriptomes
    • Blencowe BJ, Ahmad S, Lee LJ, (2009) Current-generation high-throughput sequencing: deepening insights into mammalian transcriptomes. Genes Dev 23: 1379-1386.
    • (2009) Genes Dev , vol.23 , pp. 1379-1386
    • Blencowe, B.J.1    Ahmad, S.2    Lee, L.J.3
  • 27
    • 65649083411 scopus 로고    scopus 로고
    • Estimating accuracy of RNA-Seq and microarrays with proteomics
    • Fu X, Fu N, Guo S, Yan Z, Xu Y, et al. (2009) Estimating accuracy of RNA-Seq and microarrays with proteomics. BMC Genomics 10: 161.
    • (2009) BMC Genomics , vol.10 , pp. 161
    • Fu, X.1    Fu, N.2    Guo, S.3    Yan, Z.4    Xu, Y.5
  • 28
    • 76249090489 scopus 로고    scopus 로고
    • BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources
    • Wu C, Orozco C, Boyer J, Leglise M, Goodale J, et al. (2009) BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources. Genome Biol 10: R130.
    • (2009) Genome Biol , vol.10
    • Wu, C.1    Orozco, C.2    Boyer, J.3    Leglise, M.4    Goodale, J.5
  • 29
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da W, Sherman BT, Lempicki RA, (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • da Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 30
  • 31
    • 0025056557 scopus 로고
    • Control of glycolysis in rat liver by glucokinase and phosphofructokinase: influence of glucose concentration
    • Torres NV, Mateo F, Riol-Cimas JM, Melendez-Hevia E, (1990) Control of glycolysis in rat liver by glucokinase and phosphofructokinase: influence of glucose concentration. Mol Cell Biochem 93: 21-26.
    • (1990) Mol Cell Biochem , vol.93 , pp. 21-26
    • Torres, N.V.1    Mateo, F.2    Riol-Cimas, J.M.3    Melendez-Hevia, E.4
  • 32
    • 77958546976 scopus 로고    scopus 로고
    • Orman MA, Arai K, Yarmush ML, Androulakis IP, Berthiaume F,et al. Metabolic flux determination in perfused livers by mass balance analysis: effect of fasting
    • Orman MA, Arai K, Yarmush ML, Androulakis IP, Berthiaume F,et al. Metabolic flux determination in perfused livers by mass balance analysis: effect of fasting. Biotechnol Bioeng 107: 825-835.
    • Biotechnol Bioeng , vol.107 , pp. 825-835
  • 33
    • 69149108764 scopus 로고    scopus 로고
    • Increased renal proximal convoluted tubule transport contributes to hypertension in Cyp4a14 knockout mice
    • Quigley R, Chakravarty S, Zhao X, Imig JD, Capdevila JH, (2009) Increased renal proximal convoluted tubule transport contributes to hypertension in Cyp4a14 knockout mice. Nephron Physiol 113: p23-28.
    • (2009) Nephron Physiol , vol.113
    • Quigley, R.1    Chakravarty, S.2    Zhao, X.3    Imig, J.D.4    Capdevila, J.H.5
  • 35
    • 28144438907 scopus 로고    scopus 로고
    • Functional characterization of human monocarboxylate transporter 6 (SLC16A5)
    • Murakami Y, Kohyama N, Kobayashi Y, Ohbayashi M, Ohtani H, et al. (2005) Functional characterization of human monocarboxylate transporter 6 (SLC16A5). Drug Metab Dispos 33: 1845-1851.
    • (2005) Drug Metab Dispos , vol.33 , pp. 1845-1851
    • Murakami, Y.1    Kohyama, N.2    Kobayashi, Y.3    Ohbayashi, M.4    Ohtani, H.5
  • 36
    • 57349175469 scopus 로고    scopus 로고
    • Effect of starvation on transcriptomes of brain and liver in adult female zebrafish (Danio rerio)
    • Drew RE, Rodnick KJ, Settles M, Wacyk J, Churchill E, et al. (2008) Effect of starvation on transcriptomes of brain and liver in adult female zebrafish (Danio rerio). Physiol Genomics 35: 283-295.
    • (2008) Physiol Genomics , vol.35 , pp. 283-295
    • Drew, R.E.1    Rodnick, K.J.2    Settles, M.3    Wacyk, J.4    Churchill, E.5
  • 38
    • 0033127072 scopus 로고    scopus 로고
    • Acute hepatic failure and defective fatty acid transport: clinical proof of a physiologic hypothesis
    • Berk PD, Stump D, (1999) Acute hepatic failure and defective fatty acid transport: clinical proof of a physiologic hypothesis. Hepatology 29: 1607-1609.
    • (1999) Hepatology , vol.29 , pp. 1607-1609
    • Berk, P.D.1    Stump, D.2
  • 39
    • 0028354055 scopus 로고
    • An upstream region of the enoyl-coenzyme A hydratase/3-hydroxyacyl-coenzyme A dehydrogenase gene directs luciferase expression in liver in response to peroxisome proliferators in transgenic mice
    • Alvares K, Fan C, Dadras SS, Yeldandi AV, Rachubinski RA, et al. (1994) An upstream region of the enoyl-coenzyme A hydratase/3-hydroxyacyl-coenzyme A dehydrogenase gene directs luciferase expression in liver in response to peroxisome proliferators in transgenic mice. Cancer Res 54: 2303-2306.
    • (1994) Cancer Res , vol.54 , pp. 2303-2306
    • Alvares, K.1    Fan, C.2    Dadras, S.S.3    Yeldandi, A.V.4    Rachubinski, R.A.5
  • 40
    • 33644654215 scopus 로고    scopus 로고
    • Fatty acid metabolism pathway play an important role in carcinogenesis of human colorectal cancers by Microarray-Bioinformatics analysis
    • Yeh CS, Wang JY, Cheng TL, Juan CH, Wu CH, et al. (2006) Fatty acid metabolism pathway play an important role in carcinogenesis of human colorectal cancers by Microarray-Bioinformatics analysis. Cancer Lett 233: 297-308.
    • (2006) Cancer Lett , vol.233 , pp. 297-308
    • Yeh, C.S.1    Wang, J.Y.2    Cheng, T.L.3    Juan, C.H.4    Wu, C.H.5
  • 41
    • 0030954707 scopus 로고    scopus 로고
    • Hepatic gluconeogenic fluxes and glycogen turnover during fasting in humans. A stable isotope study
    • Hellerstein MK, Neese RA, Linfoot P, Christiansen M, Turner S, et al. (1997) Hepatic gluconeogenic fluxes and glycogen turnover during fasting in humans. A stable isotope study. J Clin Invest 100: 1305-1319.
    • (1997) J Clin Invest , vol.100 , pp. 1305-1319
    • Hellerstein, M.K.1    Neese, R.A.2    Linfoot, P.3    Christiansen, M.4    Turner, S.5
  • 42
    • 0033847132 scopus 로고    scopus 로고
    • Phosphoenolpyruvate carboxykinase is necessary for the integration of hepatic energy metabolism
    • She P, Shiota M, Shelton KD, Chalkley R, Postic C, et al. (2000) Phosphoenolpyruvate carboxykinase is necessary for the integration of hepatic energy metabolism. Mol Cell Biol 20: 6508-6517.
    • (2000) Mol Cell Biol , vol.20 , pp. 6508-6517
    • She, P.1    Shiota, M.2    Shelton, K.D.3    Chalkley, R.4    Postic, C.5
  • 43
    • 0141923625 scopus 로고    scopus 로고
    • The refeeding syndrome and hypophosphatemia
    • Marinella MA, (2003) The refeeding syndrome and hypophosphatemia. Nutr Rev 61: 320-323.
    • (2003) Nutr Rev , vol.61 , pp. 320-323
    • Marinella, M.A.1
  • 45
    • 0037648878 scopus 로고    scopus 로고
    • Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: recent developments
    • Somsak L, Nagya V, Hadady Z, Docsa T, Gergely P, (2003) Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: recent developments. Curr Pharm Des 9: 1177-1189.
    • (2003) Curr Pharm Des , vol.9 , pp. 1177-1189
    • Somsak, L.1    Nagya, V.2    Hadady, Z.3    Docsa, T.4    Gergely, P.5
  • 46
    • 41649102414 scopus 로고    scopus 로고
    • Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice
    • Mody N, Graham TE, Tsuji Y, Yang Q, Kahn BB, (2008) Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice. Am J Physiol Endocrinol Metab 294: E785-793.
    • (2008) Am J Physiol Endocrinol Metab , vol.294
    • Mody, N.1    Graham, T.E.2    Tsuji, Y.3    Yang, Q.4    Kahn, B.B.5
  • 47
    • 67349139275 scopus 로고    scopus 로고
    • Assessing the potential of glucokinase activators in diabetes therapy
    • Matschinsky FM, (2009) Assessing the potential of glucokinase activators in diabetes therapy. Nat Rev Drug Discov 8: 399-416.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 399-416
    • Matschinsky, F.M.1
  • 48
    • 0030681260 scopus 로고    scopus 로고
    • The significance of digital gene expression profiles
    • Audic S, Claverie JM, (1997) The significance of digital gene expression profiles. Genome Res 7: 986-995.
    • (1997) Genome Res , vol.7 , pp. 986-995
    • Audic, S.1    Claverie, J.M.2
  • 49
    • 0035829361 scopus 로고    scopus 로고
    • Controlling the false discovery rate in behavior genetics research
    • Benjamini Y, Drai D, Elmer G, Kafkafi N, Golani I, (2001) Controlling the false discovery rate in behavior genetics research. Behav Brain Res 125: 279-284.
    • (2001) Behav Brain Res , vol.125 , pp. 279-284
    • Benjamini, Y.1    Drai, D.2    Elmer, G.3    Kafkafi, N.4    Golani, I.5
  • 50
    • 84863304598 scopus 로고    scopus 로고
    • R: A Language and Enviroment for Statistical Computing. 2.11.1 ed
    • Team RDC, Vienna, Austria, R Foundatioin for Statistical Computing
    • Team RDC (2010) R: A Language and Enviroment for Statistical Computing. 2.11.1 ed. Vienna, Austria R Foundatioin for Statistical Computing.
    • (2010)
  • 51
    • 0034069495 scopus 로고    scopus 로고
    • Gene ontology: tool for the unification of biology. The Gene Ontology Consortium
    • Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, et al. (2000) Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 25: 25-29.
    • (2000) Nat Genet , vol.25 , pp. 25-29
    • Ashburner, M.1    Ball, C.A.2    Blake, J.A.3    Botstein, D.4    Butler, H.5
  • 54
    • 0242490780 scopus 로고    scopus 로고
    • Cytoscape: a software environment for integrated models of biomolecular interaction networks
    • Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, et al. (2003) Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res 13: 2498-2504.
    • (2003) Genome Res , vol.13 , pp. 2498-2504
    • Shannon, P.1    Markiel, A.2    Ozier, O.3    Baliga, N.S.4    Wang, J.T.5


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