β-Cell-specific pyruvate dehydrogenase deficiency impairs glucose-stimulated insulin secretion

American Journal of Physiology - Endocrinology and Metabolism

Volumn 299, Issue 6, 2010, Pages

  Srinivasan, Malathi ^a   Choi, Cheol S ^b,c   Ghoshal, Pushpankur ^a   Pliss, Lioudmila ^a   Pandya, Jignesh D ^a   Hill, David ^d   Cline, Gary ^b   Patel, Mulchand S ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Gachon University College of Medicine   (South Korea)

^d LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

Author keywords

cell hypertrophy; Pyruvate cycling

Indexed keywords

GLUCOSE; INSULIN; PYRUVATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE COMPLEX;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL ISOLATION; CELL SIZE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFICIENCY; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; AGE; ANIMAL; BLOOD; DRUG EFFECT; GLUCOSE TOLERANCE TEST; METABOLISM; MOUSE MUTANT; SECRETION;

AGE FACTORS; ANIMALS; GLUCOSE; GLUCOSE TOLERANCE TEST; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; MICE, KNOCKOUT; PYRUVATE DEHYDROGENASE COMPLEX;

EID: 78649665323     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00339.2010     Document Type: Article

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