Featured Article: Beta cell specific pyruvate dehydrogenase alpha gene deletion results in a reduced islet number and β-cell mass postnatally

Experimental Biology and Medicine

Volumn 239, Issue 8, 2014, Pages 975-985

  Patel, Mulchand S ^a   Srinivasan, Malathi ^a   Strutt, Brenda ^b   Mahmood, Saleh ^a   Hill, David J ^b,c  

^a UNIVERSITY AT BUFFALO   (United States)

^b ST JOSEPH S HEALTH CENTRE   (Canada)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

insulin secretion; Pdx1 expression; Pyruvate dehydrogenase complex deficiency; cell mass; cell maturity

Indexed keywords

GLUCOSE; INSULIN; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 3; PANCREATIC INSULIN; PYRUVATE DEHYDROGENASE COMPLEX; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA ISOLATION; FEMALE; GENE; GENE EXPRESSION; GENE SILENCING; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; INSULIN RELEASE; MALE; MATING; MORPHOLOGY; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PHENOTYPE; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PYRUVATE DEHYDROGENASE ALPHA 1 GENE; QUANTITATIVE POLYMERASE CHAIN REACTION; RADIOIMMUNOASSAY; REAL TIME POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE;

EID: 84907070978     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370214531895     Document Type: Article

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