Acrylamide induces mitochondrial dysfunction and apoptosis in BV-2 microglial cells

Free Radical Biology and Medicine

Volumn 84, Issue , 2015, Pages 42-53

  Liu, Zhigang ^a,b   Song, Ge ^a   Zou, Chen ^a   Liu, Gongguan ^a   Wu, Wanqiang ^a   Yuan, Tian ^a   Liu, Xuebo ^a  

^a NORTHWEST A F UNIVERSITY   (China)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Acrylamide; Apoptosis; Energy metabolism; Microglia; Mitochondrial dysfunction; Redox signaling

Indexed keywords

ACETYLCYSTEINE; ACRYLAMIDE; CYTOCHROME C OXIDASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROTEIN KINASE B; PYRUVATE DEHYDROGENASE COMPLEX; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NRF2; UBIQUINOL CYTOCHROME C REDUCTASE;

ANAEROBIC GLYCOLYSIS; ANIMAL CELL; APOPTOSIS; ARTICLE; BCL 2 BAX RATIO; CELL ACTIVATION; CELL DAMAGE; CELL ENERGY; CELL FUNCTION; CELL METABOLISM; CELL SIZE; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CELLULAR PARAMETERS; CHROMATIN CONDENSATION; CONTROLLED STUDY; ELECTROPHILICITY; MICROGLIA; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; WESTERN BLOTTING; ANIMAL; CELL LINE; DRUG EFFECTS; MEMBRANE POTENTIAL; METABOLISM; MITOCHONDRION; OXYGEN CONSUMPTION; PHYSIOLOGY;

ACRYLAMIDE; ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIALS; MICE; MICROGLIA; MITOCHONDRIA; OXIDATION-REDUCTION; OXYGEN CONSUMPTION;

EID: 84928537114     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.03.013     Document Type: Article

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