Antioxidant activity of N-acetylcysteine, flavonoids and α-tocopherol on endometrial cells in culture

Journal of Reproductive Immunology

Volumn 75, Issue 1, 2007, Pages 1-10

  Estany, S ^a   Palacio, J R ^a   Barnadas, R ^a   Sabes, M ^a   Iborra, A ^a   Martinez P ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Tocopherol; Endometrial cell; Flavonoid; N Acetylcysteine; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; CATECHIN; FLAVONOID; HYDROGEN PEROXIDE; LIPOSOME; QUERCETIN;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG EFFECT; ENDOMETRIUM CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL;

ACETYLCYSTEINE; ALPHA-TOCOPHEROL; ANTIOXIDANTS; CELL LINE, TUMOR; CELL SURVIVAL; ENDOMETRIAL NEOPLASMS; ENDOMETRIUM; FEMALE; FLAVONOIDS; HUMANS; HYDROGEN PEROXIDE; LIPOSOMES; OXIDANTS; OXIDATIVE STRESS;

EID: 34447552660     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2007.01.007     Document Type: Article

References (42)

1. Abudu N., Miller J.J., Attaelmannan M., and Levinson S.S. Vitamins in human arteriosclerosis with emphasis on vitamin C and vitamin E. Clin. Chim. Acta 339 (2004) 11-25
2. Agarwal A., Gupta S., and Sharma R.K. Role of oxidative stress in female reproduction. Reprod. Biol. Endocrinol. 3 (2005) 28
3. Agarwal A., Saleh R.A., and Bedaiwy M.A. Role of reactive oxygen species in the pathophysiology of human reproduction. Fertil. Steril. 79 (2003) 829-843
4. Aruoma O.I., Halliwell B., Hoey B.M., and Butler J. The antioxidant action of N-acetylcysteine: Its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. Free Radic. Biol. Med. 6 (1989) 593-597
5. Bechoua S., Dubois M., Dominguez Z., Goncalves A., Nemoz G., Lagarde M., and Prigent A.F. Protective effect of docosahexaenoic acid against hydrogen peroxide-induced oxidative stress in human lymphocytes. Biochem. Pharmacol. 57 (1999) 1021-1030
6. Bedaiwy M.A., Goldberg J.M., Falcone T., Singh M., Nelson D., Azab H., Wang X., and Sharma R. Relationship between oxidative stress and embryotoxicity of hydrosalpingeal fluid. Hum. Reprod. 17 (2002) 601-604
7. Black P.H., and Garbutt L.D. Stress, inflammation and cardiovascular disease. J. Psychosom. Res. 52 (2002) 1-23
8. Bors W., Heller W., Michel C., and Saran M. Flavonoids as antioxidants: determination of radical-scavenging efficiencies. Methods Enzymol. 186 (1990) 343-355
9. Buhimschi I.A., Buhimschi C.S., and Weiner C.P. Protective effect of N-acetylcysteine against fetal death and preterm labor induced by maternal inflammation. Am. J. Obstet. Gynecol. 188 (2002) 203-208
10. Cao G., Sofic E., and Prior R.L. Antioxidant and prooxidant behavior of flavonoids: structure-activity relationships. Free Radic. Biol. Med. 22 (1997) 749-760
11. Curtin J.F., Donovan M., and Cotter T.G. Regulation and measurement of oxidative stress in apoptosis. J. Immunol. Methods 265 (2002) 49-72
12. Dam B., Hinsbergh V.W.M., Stehouwer C.D.A., Versteilen A., Dekker H., Buytenhek R., Princen H.M., and Schalkwijk C.G. Vitamin E inhibits lipid peroxidation-induced adhesion molecule expression in endothelial cells and decreases soluble cell adhesion molecules in healthy subjects. Cardiovasc. Res. 57 (2003) 563-571
13. Edenharder R., and Grünhage D. Free radical-scavenging abilities of flavonoids as mechanism of protection against mutagenicity induced by tert-butyl hydroperoxide or cumene hydroperoxide in Salmonella typhimurium TA102. Mutat. Res. 540 (2003) 1-18
14. Elliott R.M., Southon S., and Archer D.B. Oxidative insult specifically decreases levels of a mitochondrial transcript. Free Radic. Biol. Med. 26 (1999) 646-655
15. Esposito E., Rotilio D., Matteo M., Giulio C., Cacchio M., and Algeri S. A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes. Neurobiol. Aging 23 (2002) 719-735
16. Gao Z., Huang K., and Xu H. Protective effects of flavonoids in the roots of Scutellaria Baicalensis Georgi against hydrogen peroxide-induced oxidative stress in hs-sy5y cells. Pharmacol. Res. 43 (2001) 173-178
17. Gilgun Y., Melaned E., and Offen D. Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier. Neuropharmacology 40 (2001) 959-975
18. Hanasaki Y., Ogawa S., and Fukui S. The correlation between active oxygens scavenging and antioxidative effects of flavonoids. Free Radic. Biol. Med. 16 (1994) 845-850
19. Horvathova K., Novotny L., and Vachalkova A. The free radical scavenging activity of four flavonoids determined by comet assay. Neoplasm 50 (2003) 291-295
20. Iborra A., Palacio J.R., and Martínez P. Oxidative stress and autoimmune response in the infertile woman. Chem. Immunol. Allergy 88 (2005) 150-162
21. John S., Kale M., Rathore N., and Bhatnagar D. Protective effect of vitamin E in dimethoate and malathion induced oxidative stress in rat erythrocytes. J. Nutr. Biochem. 12 (2001) 500-504
22. Kalender S., Kalender Y., Ogutcu A., Uzunhisarcikli M., Durak D., and Açikgoz F. Endosulfan-induced cardiotoxicity and free radical metabolism in rats: the protective effect of vitamin E. Toxicology 202 (2004) 227-235
23. Kim M.S., Lee J., Lee K.M., Yang S.H., Choi S., Chung S.Y., Kim T.Y., Jeong W.H., and Park R. Involvement of hydrogen peroxide in mistletoe lectin-II-induced apoptosis of myeloleukemic U937 cells. Life Sci. 73 (2003) 1231-1243
24. Laughton M.J., Halliwell B., Evans P.J., and Hoult J.R. Antioxidant and pro-oxidant actions of the plant phenolics quercetin, gossypol and myricetin. Effects on lipid peroxidation, hydroxyl radical generation and bleomycin-dependent damage to DNA. Biochem. Pharmacol. 38 (1989) 2859-2865
25. Lee W.R., Shen S.C., Lin H.Y., Hou W.C., Yang L.L., and Chen Y.C. Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca2+-dependent endonuclease. Biochem. Pharmacol. 63 (2002) 225-236
26. Lopaczynski W., and Zeisel S. Antioxidants, programmed cell death, and cancer. Nutr. Res. 21 (2001) 295-307
27. Marchand L.L. Cancer preventive effects of flavonoids-a review. Biomed. Pharmacother. 56 (2002) 296-301
28. Mayorga M., Iborra A., Estany S., and Martinez P. Protective effect of vitamin E in an animal model of LPS-induced inflammation. Am. J. Reprod. Immunol. 52 (2004) 356-361
29. Moldéus P., and Cotgreave I.A. N-Acetylcysteine. Methods Enzymol. 234 (1994) 482-493
30. Morris C.D., and Carson S. Routine vitamin supplementation to prevent cardiovascular disease: a summary of the evidence for the U.S. preventive services task force. Ann. Intern. Med. 139 (2003) 56-70
31. Nijveldt R.J., Nood E., Hoorn D.E.C., Boelens P.G., Norren K., and Leeuwen P.A.M. Flavonoids: a review of probable mechanisms of action and potential applications. Am. J. Clin. Nutr. 74 (2001) 418-425
32. Ohta Y., Yamasaki T., Niwa T., Majima Y., and Ishiguro I. Preventive effect of topical vitamin E-containing liposome instillation on the progression of galactose cataract. Comparison between 5-week- and 12-week-old rats fed a 25% galactose diet. Exp. Eye Res. 68 (1999) 747-755
33. Osakada F., Hashino A., Kume T., Katsuki H., Kaneko S., and Akaike A. α-Tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons. Neuropharmacology 47 (2004) 904-915
34. Rice-Evans C.A., Miller N.J., and Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Rad. Biol. Med. 20 (1996) 933-956
35. Sadowska A.M., Manuel-y-Keenoy B., and De Backer W.A. Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: Discordant in vitro and in vivo dose-effects: a review. Pulm. Pharmacol. Ther. 20 (2007) 9-22
36. Senthil K., Aranganathan S., and Nalini N. Evidence of oxidative stress in the circulation of ovarian cancer patients. Clin. Chim. Acta 339 (2004) 27-32
37. Sentürker S., Tschirret-Guth R., Morrow J., Levine R., and Shacter E. Induction of apoptosis by chemotherapeutic drugs without generation of reactive oxygen species. Arch. Biochem. Biophys. 397 (2002) 262-272
38. Shimpuku H., Tachi Y., Shinohara M., and Ohura K. Effect of vitamin E on the degradation of hydrogen peroxide in cultured human umbilical vein endothelial cells. Life Sci. 68 (2000) 353-359
39. Stone J.R., and Yang S. Hydrogen peroxide: a signaling messenger. Antioxid. Redox Signal. 8 (2006) 243-270
40. Vivekananthan D.P., Penn M.S., Sapp S.K., Hsu A., and Topol E.J. Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials. Lancet 361 (2003) 2017-2023
41. Wu M.J., Wang L., Weng C.Y., and Yen J.H. Antioxidant activity of methanol extract of the lotus leaf (Nelumbo nucifera Gertn.). Am. J. Chin. Med. 31 (2003) 687-698
42. Zafarullah M., Li W.Q., Sylvester J., and Ahmad M. Molecular mechanisms of N-acetylcysteine actions. Cell. Mol. Life Sci. 60 (2003) 6-20