An evolutionary history of defensins: A role for copy number variation in maximizing host innate and adaptive immune responses

Frontiers in Immunology

Volumn 6, Issue MAR, 2015, Pages

  Machado, Lee R ^a   Ottolini, Barbara ^b  

^a UNIVERSITY OF NORTHAMPTON   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Copy number variation; Crohn's disease; Defensins; HIV; Psoriasis

Indexed keywords

BETA DEFENSIN; BETA DEFENSIN 2; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CXCR4; DEFENSIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GAMMA INTERFERON; MELANOCORTIN 1 RECEPTOR; METALLOPROTEINASE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4;

ADAPTIVE IMMUNITY; ANTIMICROBIAL ACTIVITY; ANTIVIRAL ACTIVITY; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BACTERIAL IMMUNITY; CD4+ T LYMPHOCYTE; CHROMOSOME 8; COPY NUMBER VARIATION; CROHN DISEASE; DISEASE ASSOCIATION; FERTILITY; GENE EXPRESSION; GENETIC VARIABILITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOMODULATION; INFLAMMATORY DISEASE; INNATE IMMUNITY; MOLECULAR EVOLUTION; NUCLEAR MAGNETIC RESONANCE; PSORIASIS; SHORT SURVEY; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURE ANALYSIS;

EID: 84926674847     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2015.00115     Document Type: Short Survey

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