Partial Deletion of Chromosome 8 β-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice

PLoS Genetics

Volumn 9, Issue 10, 2013, Pages

  Zhou, Yu S ^a   Webb, Sheila ^a   Lettice, Laura ^a   Tardif, Steve ^b,e   Kilanowski, Fiona ^a   Tyrrell, Christine ^a   MacPherson, Heather ^a   Semple, Fiona ^a   Tennant, Peter ^a   Baker, Tina ^a   Hart, Alan ^a   Devenney, Paul ^a   Perry, Paul ^a   Davey, Tracey ^c   Barran, Perdita ^d   Barratt, Chris L ^b   Dorin, Julia R ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d School of Chemistry Joseph Black Building   (United Kingdom)

^e R and D Andrology Division Minitube of America   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN; CALCIUM;

ACROSOME REACTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AXONEME; BETA DEFENSIN GENE; CALCIUM CELL LEVEL; CHROMOSOME 8; CONTROLLED STUDY; EMBRYO; EPIDIDYMIS; EPIDIDYMIS TAIL; FEMALE; GENE CLUSTER; GENE DELETION; IN VIVO STUDY; MALE; MALE GENITAL TRACT PARAMETERS; MALE INFERTILITY; MICROTUBULE; MOUSE; MOUSE MUTANT; NONHUMAN; OOCYTE; SEMEN ANALYSIS; SPERMATOZOON; SPERMATOZOON ABNORMALITY; SPERMATOZOON CAPACITATION; SPERMATOZOON FRAGILITY; SPERMATOZOON HEAD; SPERMATOZOON MATURATION; SPERMATOZOON MOTILITY; SPERMATOZOON PENETRATION; TESTIS; WILD TYPE; ZONA PELLUCIDA; ANIMAL; CHROMOSOME; CHROMOSOME DELETION; GENETICS; METABOLISM; PATHOLOGY;

ANIMALS; BETA-DEFENSINS; CHROMOSOME DELETION; CHROMOSOMES; INFERTILITY, MALE; MALE; MICE; SPERM MATURATION; SPERMATOZOA;

EID: 84887263574     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003826     Document Type: Article

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