Whole Cigarette Smoke Increased the Expression of TLRs, HBDs, and Proinflammory Cytokines by Human Gingival Epithelial Cells through Different Signaling Pathways

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Semlali, Abdelhabib ^a,b   Witoled, Chmielewski ^a   Alanazi, Mohammed ^b   Rouabhia, Mahmoud ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BETA DEFENSIN 2; BETA DEFENSIN 3; CIGARETTE SMOKE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 6;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; EPITHELIUM CELL; GENE TRANSLOCATION; GINGIVA; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MODULATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SMOKING;

BETA-DEFENSINS; CELLS, CULTURED; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; GINGIVA; HUMANS; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; PHOSPHORYLATION; PLANT PREPARATIONS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SMOKE; SMOKING; TOBACCO; TOLL-LIKE RECEPTORS;

EID: 84871705673     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0052614     Document Type: Article

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