-
1
-
-
0028920049
-
Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides
-
Abdel-Malek Z, Swope VB, Suzuki I et al. (1995) Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides. Proc Natl Acad Sci USA 92:1789-93
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1789-1793
-
-
Abdel-Malek, Z.1
Swope, V.B.2
Suzuki, I.3
-
2
-
-
0035064572
-
The melanocortin 1 receptor is the principal mediator of the effects of agouti signaling protein on mammalian melanocytes
-
Abdel-Malek ZA, Scott MC, Furumura M et al. (2001) The melanocortin 1 receptor is the principal mediator of the effects of agouti signaling protein on mammalian melanocytes. J Cell Sci 114:1019-24
-
(2001)
J Cell Sci
, vol.114
, pp. 1019-1024
-
-
Abdel-Malek, Z.A.1
Scott, M.C.2
Furumura, M.3
-
3
-
-
0035976916
-
Desensitization of the Y1 cell adrenocorticotropin receptor: Evidence for a restricted heterologous mechanism implying a role for receptor-effector complexes
-
Baig AH, Swords FM, Noon LA et al. (2001) Desensitization of the Y1 cell adrenocorticotropin receptor: evidence for a restricted heterologous mechanism implying a role for receptor-effector complexes. J Biol Chem 276:44792-7
-
(2001)
J Biol Chem
, vol.276
, pp. 44792-44797
-
-
Baig, A.H.1
Swords, F.M.2
Noon, L.A.3
-
4
-
-
26444449038
-
Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk
-
Beaumont KA, Newton RA, Smit DJ et al. (2005) Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk. Hum Mol Genet 14:2145-54
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2145-2154
-
-
Beaumont, K.A.1
Newton, R.A.2
Smit, D.J.3
-
5
-
-
79955930958
-
Melanocortin MC receptor in human genetics and model systems
-
Beaumont KA, Wong SS, Ainger SA et al. (2011) Melanocortin MC receptor in human genetics and model systems. Eur J Pharmacol 660:103-10
-
(2011)
Eur J Pharmacol
, vol.660
, pp. 103-110
-
-
Beaumont, K.A.1
Wong, S.S.2
Ainger, S.A.3
-
6
-
-
0034837773
-
MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations
-
Box NF, Duffy DL, Chen W et al. (2001) MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations. Am J Hum Genet 69:765-73
-
(2001)
Am J Hum Genet
, vol.69
, pp. 765-773
-
-
Box, N.F.1
Duffy, D.L.2
Chen, W.3
-
7
-
-
0030782275
-
Characterization of melanocyte stimulating hormone receptor variant alleles in twins with red hair
-
Box NF, Wyeth JR, O'Gorman LE et al. (1997) Characterization of melanocyte stimulating hormone receptor variant alleles in twins with red hair. Hum Mol Gen 6:1891-7
-
(1997)
Hum Mol Gen
, vol.6
, pp. 1891-1897
-
-
Box, N.F.1
Wyeth, J.R.2
O'Gorman, L.E.3
-
8
-
-
0344780741
-
G-protein coupled receptor kinases as modulators of G-protein signalling
-
Bunemann M, Hosey MM (1999) G-protein coupled receptor kinases as modulators of G-protein signalling. J Physiol 517(Part 1):5-23
-
(1999)
J Physiol
, vol.517
, Issue.PART 1
, pp. 5-23
-
-
Bunemann, M.1
Hosey, M.M.2
-
9
-
-
33751048740
-
Cell signaling and trafficking of human melanocortin receptors in real time using two-photon fluorescence and confocal laser microscopy: Differentiation of agonists and antagonists
-
Cai M, Varga EV, Stankova M et al. (2006) Cell signaling and trafficking of human melanocortin receptors in real time using two-photon fluorescence and confocal laser microscopy: differentiation of agonists and antagonists. Chem Biol Drug Des 68:183-93
-
(2006)
Chem Biol Drug des
, vol.68
, pp. 183-193
-
-
Cai, M.1
Varga, E.V.2
Stankova, M.3
-
10
-
-
36749008499
-
A-defensin mutation causes black coat color in domestic dogs
-
Candille SI, Kaelin CB, Cattanach BM et al. (2007) A-defensin mutation causes black coat color in domestic dogs. Science 318:1418-23
-
(2007)
Science
, vol.318
, pp. 1418-1423
-
-
Candille, S.I.1
Kaelin, C.B.2
Cattanach, B.M.3
-
11
-
-
0027103724
-
The expression of functional MSH receptors on cultured human melanocytes
-
Donatien PD, Hunt G, Pieron C et al. (1992) The expression of functional MSH receptors on cultured human melanocytes. Arch Dermatol Res 284:424-6
-
(1992)
Arch Dermatol Res
, vol.284
, pp. 424-426
-
-
Donatien, P.D.1
Hunt, G.2
Pieron, C.3
-
12
-
-
0035101820
-
Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling
-
Ferguson SS (2001) Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev 53:1-24
-
(2001)
Pharmacol Rev
, vol.53
, pp. 1-24
-
-
Ferguson, S.S.1
-
13
-
-
0031868040
-
Modulation of melanocyte-stimulating hormone receptor expression on normal human melanocytes: Evidence for a regulatory role of ultraviolet B, interleukin-1alpha, interleukin-1beta, endothelin-1 and tumour necrosis factor-alpha
-
Funasaka Y, Chakraborty AK, Hayashi Y et al. (1998) Modulation of melanocyte-stimulating hormone receptor expression on normal human melanocytes: evidence for a regulatory role of ultraviolet B, interleukin-1alpha, interleukin-1beta, endothelin-1 and tumour necrosis factor-alpha. Br J Dermatol 139:216-24
-
(1998)
Br J Dermatol
, vol.139
, pp. 216-224
-
-
Funasaka, Y.1
Chakraborty, A.K.2
Hayashi, Y.3
-
16
-
-
0035937107
-
Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic
-
Harder J, Bartels J, Christophers E et al. (2001) Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic. J Biol Chem 276:5707-13
-
(2001)
J Biol Chem
, vol.276
, pp. 5707-5713
-
-
Harder, J.1
Bartels, J.2
Christophers, E.3
-
17
-
-
33745757131
-
Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes
-
Hauser JE, Kadekaro AL, Kavanagh RJ et al. (2006) Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes. Pigment Cell Res 19:303-14
-
(2006)
Pigment Cell Res
, vol.19
, pp. 303-314
-
-
Hauser, J.E.1
Kadekaro, A.L.2
Kavanagh, R.J.3
-
18
-
-
19544392728
-
Eumelanin and pheomelanin concentrations in human epidermis before and after UVB irradiation
-
Hennessy A, Oh C, Diffey B et al. (2005) Eumelanin and pheomelanin concentrations in human epidermis before and after UVB irradiation. Pigment Cell Res 18:220-3
-
(2005)
Pigment Cell Res
, vol.18
, pp. 220-223
-
-
Hennessy, A.1
Oh, C.2
Diffey, B.3
-
19
-
-
0028981255
-
7 α-melanocytestimulating hormone increases the eumelanin:phaeomelanin ratio in cultured human melanocytes
-
Hunt G, Kyne S, Wakamatsu K et al. (1995) Nle4DPhe7 α- melanocytestimulating hormone increases the eumelanin:phaeomelanin ratio in cultured human melanocytes. J Invest Dermatol 104:83-5
-
(1995)
J Invest Dermatol
, vol.104
, pp. 83-85
-
-
Hunt, G.1
Kyne, S.2
Wakamatsu, K.3
-
20
-
-
0031963866
-
Activation of the cyclic AMP pathway by a-melanotropin mediates the response of human melanocytes to ultraviolet B radiation
-
Im S, Moro O, Peng F et al. (1998) Activation of the cyclic AMP pathway by a-melanotropin mediates the response of human melanocytes to ultraviolet B radiation. Cancer Res 58:47-54
-
(1998)
Cancer Res
, vol.58
, pp. 47-54
-
-
Im, S.1
Moro, O.2
Peng, F.3
-
21
-
-
20144377250
-
A-Melanocortin and endothelin-1 activate anti-apoptotic pathways and reduce DNA damage in human melanocytes
-
Kadekaro AL, Kavanagh R, Kanto H et al. (2005) a-Melanocortin and endothelin-1 activate anti-apoptotic pathways and reduce DNA damage in human melanocytes. Cancer Res 65:4292-9
-
(2005)
Cancer Res
, vol.65
, pp. 4292-4299
-
-
Kadekaro, A.L.1
Kavanagh, R.2
Kanto, H.3
-
22
-
-
77957856003
-
Melanocortin 1 receptor genotype: An important determinant of the damage response of melanocytes to ultraviolet radiation
-
Kadekaro AL, Leachman S, Kavanagh RJ et al. (2010) Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation. FASEB J 24:3850-60
-
(2010)
FASEB J
, vol.24
, pp. 3850-3860
-
-
Kadekaro, A.L.1
Leachman, S.2
Kavanagh, R.J.3
-
23
-
-
0035722059
-
Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color
-
Kennedy C, ter Huurne J, Berkhout M et al. (2001) Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color. J Invest Dermatol 117:294-300
-
(2001)
J Invest Dermatol
, vol.117
, pp. 294-300
-
-
Kennedy, C.1
Ter Huurne, J.2
Berkhout, M.3
-
24
-
-
77953977632
-
Expression of antimicrobial peptides in cutaneous infections after skin surgery
-
Kesting MR, Stoeckelhuber M, Holzle F et al. (2010) Expression of antimicrobial peptides in cutaneous infections after skin surgery. Br J Dermatol 163:121-7
-
(2010)
Br J Dermatol
, vol.163
, pp. 121-127
-
-
Kesting, M.R.1
Stoeckelhuber, M.2
Holzle, F.3
-
25
-
-
33645877973
-
Human melanocortin receptor 2 expression and functionality: Effects of protein kinase A and protein kinase C on desensitization and internalization
-
Kilianova Z, Basora N, Kilian P et al. (2006) Human melanocortin receptor 2 expression and functionality: effects of protein kinase A and protein kinase C on desensitization and internalization. Endocrinol 147:2325-37
-
(2006)
Endocrinol
, vol.147
, pp. 2325-2337
-
-
Kilianova, Z.1
Basora, N.2
Kilian, P.3
-
26
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T))
-
Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402-8
-
(2001)
Method. Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
28
-
-
0026800892
-
The cloning of a family of genes that encode the melanocortin receptors
-
Mountjoy KG, Robbins LS, Mortrud MT et al. (1992) The cloning of a family of genes that encode the melanocortin receptors. Science 257:1248-51
-
(1992)
Science
, vol.257
, pp. 1248-1251
-
-
Mountjoy, K.G.1
Robbins, L.S.2
Mortrud, M.T.3
-
29
-
-
0030764741
-
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
-
Ollmann MM, Wilson BD, Yang Y-K et al. (1997) Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278:135-8
-
(1997)
Science
, vol.278
, pp. 135-138
-
-
Ollmann, M.M.1
Wilson, B.D.2
Yang, Y.-K.3
-
30
-
-
0033910271
-
Melanocortin-1 receptor polymorphisms and risk of melanoma: Is the association explained solely by pigmentation phenotype?
-
Palmer JS, Duffy DL, Box N et al. (2000) Melanocortin-1 receptor polymorphisms and risk of melanoma: Is the association explained solely by pigmentation phenotype? Am J Hum Genet 66:176-86
-
(2000)
Am J Hum Genet
, vol.66
, pp. 176-186
-
-
Palmer, J.S.1
Duffy, D.L.2
Box, N.3
-
32
-
-
33947375174
-
Physiological roles of G protein-coupled receptor kinases and arrestins
-
Premont RT, Gainetdinov RR (2007) Physiological roles of G protein-coupled receptor kinases and arrestins. Annu Rev Physiol 69:511-34
-
(2007)
Annu Rev Physiol
, vol.69
, pp. 511-534
-
-
Premont, R.T.1
Gainetdinov, R.R.2
-
33
-
-
33646162635
-
GRKs and beta-arrestins: Roles in receptor silencing, trafficking and signaling
-
Reiter E, Lefkowitz RJ (2006) GRKs and beta-arrestins: roles in receptor silencing, trafficking and signaling. Trends Endocrinol Metab 17:159-65
-
(2006)
Trends Endocrinol Metab
, vol.17
, pp. 159-165
-
-
Reiter, E.1
Lefkowitz, R.J.2
-
34
-
-
6344275551
-
Pharmacological characterization of loss of function mutations of the human melanocortin 1 receptor that are associated with red hair
-
Ringholm A, Klovins J, Rudzish R et al. (2004) Pharmacological characterization of loss of function mutations of the human melanocortin 1 receptor that are associated with red hair. J Invest Dermatol 123:917-23
-
(2004)
J Invest Dermatol
, vol.123
, pp. 917-923
-
-
Ringholm, A.1
Klovins, J.2
Rudzish, R.3
-
35
-
-
0027413475
-
Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function
-
Robbins LS, Nadeau JH, Johnson KR et al. (1993) Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function. Cell 72:827-34
-
(1993)
Cell
, vol.72
, pp. 827-834
-
-
Robbins, L.S.1
Nadeau, J.H.2
Johnson, K.R.3
-
36
-
-
33644765872
-
Dimerization of the human melanocortin 1 receptor: Functional consequences and dominant-negative effects
-
Sanchez-Laorden BL, Sanchez-Mas J, Martinez-Alonso E et al. (2006) Dimerization of the human melanocortin 1 receptor: functional consequences and dominant-negative effects. J Invest Dermatol 126:172-81
-
(2006)
J Invest Dermatol
, vol.126
, pp. 172-181
-
-
Sanchez-Laorden, B.L.1
Sanchez-Mas, J.2
Martinez-Alonso, E.3
-
37
-
-
15444365234
-
Role of G protein-coupled receptor kinases in the homologous desensitization of the human and mouse melanocortin 1 receptors
-
Sanchez-Mas J, Guillo LA, Zanna P et al. (2005) Role of G protein-coupled receptor kinases in the homologous desensitization of the human and mouse melanocortin 1 receptors. Mol Endocrinol 19:1035-48
-
(2005)
Mol Endocrinol
, vol.19
, pp. 1035-1048
-
-
Sanchez-Mas, J.1
Guillo, L.A.2
Zanna, P.3
-
38
-
-
19944413653
-
Beta defensin-3 engineered epidermis shows highly protective effect for bacterial infection
-
Sawamura D, Goto M, Shibaki A et al. (2005) Beta defensin-3 engineered epidermis shows highly protective effect for bacterial infection. Gene Ther 12:857-61
-
(2005)
Gene Ther
, vol.12
, pp. 857-861
-
-
Sawamura, D.1
Goto, M.2
Shibaki, A.3
-
39
-
-
18744402160
-
Regulation of the human melanocortin 1 receptor expression in epidermal melanocytes by paracrine and endocrine factors, and by UV radiation
-
Scott MC, Suzuki I, Abdel-Malek ZA (2002a) Regulation of the human melanocortin 1 receptor expression in epidermal melanocytes by paracrine and endocrine factors, and by UV radiation. Pigment Cell Res 15:433-9
-
(2002)
Pigment Cell Res
, vol.15
, pp. 433-439
-
-
Scott, M.C.1
Suzuki, I.2
Abdel-Malek, Z.A.3
-
40
-
-
0036591966
-
Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation
-
Scott MC, Wakamatsu K, Ito S et al. (2002b) Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation. J Cell Sci 115:2349-55
-
(2002)
J Cell Sci
, vol.115
, pp. 2349-2355
-
-
Scott, M.C.1
Wakamatsu, K.2
Ito, S.3
-
41
-
-
0037387146
-
Regulation of melanocortin-4 receptor signaling: Agonist-mediated desensitization and internalization
-
Shinyama H, Masuzaki H, Fang H et al. (2003) Regulation of melanocortin-4 receptor signaling: agonist-mediated desensitization and internalization. Endocrinology 144:1301-14
-
(2003)
Endocrinology
, vol.144
, pp. 1301-1314
-
-
Shinyama, H.1
Masuzaki, H.2
Fang, H.3
-
43
-
-
7144254441
-
Melanocortin 1 receptor variants in Irish population
-
Smith R, Healy E, Siddiqui S et al. (1998) Melanocortin 1 receptor variants in Irish population. J Invest Dermatol 111:119-22
-
(1998)
J Invest Dermatol
, vol.111
, pp. 119-122
-
-
Smith, R.1
Healy, E.2
Siddiqui, S.3
-
44
-
-
0029863304
-
Binding of melanotropic hormones to the melanocortin receptor MC1R on human melanocytes stimulates proliferation and melanogenesis
-
Suzuki I, Cone R, Im S et al. (1996) Binding of melanotropic hormones to the melanocortin receptor MC1R on human melanocytes stimulates proliferation and melanogenesis. Endocrinology 137:1627-33
-
(1996)
Endocrinology
, vol.137
, pp. 1627-1633
-
-
Suzuki, I.1
Cone, R.2
Im, S.3
-
45
-
-
0030970586
-
Agouti signaling protein inhibits melanogenesis and the response of human melanocytes to a-melanotropin
-
Suzuki I, Tada A, Ollmann MM et al. (1997) Agouti signaling protein inhibits melanogenesis and the response of human melanocytes to a-melanotropin. J Invest Dermatol 108:838-42
-
(1997)
J Invest Dermatol
, vol.108
, pp. 838-842
-
-
Suzuki, I.1
Tada, A.2
Ollmann, M.M.3
-
46
-
-
0021206553
-
Action of the e locus of mice in the response of phaeomelanic hair follicles to α-melanocyte-stimulating hormone in vitro
-
Tamate HB, Takeuchi T (1984) Action of the e locus of mice in the response of phaeomelanic hair follicles to α-melanocyte-stimulating hormone in vitro. Science 224:1241-2
-
(1984)
Science
, vol.224
, pp. 1241-1242
-
-
Tamate, H.B.1
Takeuchi, T.2
-
47
-
-
0028231062
-
Obesity, diabetes, and neoplasia in yellow A(vy)/- mice: Ectopic expression of the agouti gene
-
Yen TT, Gill AM, Frigeri LG et al. (1994) Obesity, diabetes, and neoplasia in yellow A(vy)/- mice: Ectopic expression of the agouti gene. FASEB J 8: 479-88
-
(1994)
FASEB J
, vol.8
, pp. 479-488
-
-
Yen, T.T.1
Gill, A.M.2
Frigeri, L.G.3
|