Synergistic anti-tumour effects of tetrandrine and chloroquine combination therapy in human cancer: A potential antagonistic role for p21

British Journal of Pharmacology

Volumn 172, Issue 9, 2015, Pages 2232-2245

  Mei, Liufeng ^a   Chen, Yicheng ^a   Wang, Zhimeng ^a   Wang, Jian ^a   Wan, Jiali ^a   Yu, Chunrong ^a   Liu, Xin ^a   Li, Wenhua ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; BAFILOMYCIN A1; CASPASE 3; CHLOROQUINE; PROTEIN KINASE B; PROTEIN P21; REACTIVE OXYGEN METABOLITE; TETRANDRINE; ANTINEOPLASTIC AGENT; BENZYLISOQUINOLINE DERIVATIVE; CASP3 PROTEIN, HUMAN; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CELL VIABILITY; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG POTENTIATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TUMOR XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; CELL SURVIVAL; COLONIC NEOPLASMS; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; GENETIC TRANSFECTION; GENETICS; HCT 116 CELL LINE; HELA CELL LINE; LUNG NEOPLASMS; METABOLISM; NUDE MOUSE; OXIDATIVE STRESS; PATHOLOGY; SIGNAL TRANSDUCTION; TIME FACTOR; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; AUTOPHAGY; BENZYLISOQUINOLINES; CASPASE 3; CELL SURVIVAL; CHLOROQUINE; COLONIC NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; HCT116 CELLS; HELA CELLS; HUMANS; LUNG NEOPLASMS; MALE; MICE, INBRED BALB C; MICE, NUDE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84926650745     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13045     Document Type: Article

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