Low-dose bafilomycin attenuates neuronal cell death associated with autophagy-lysosome pathway dysfunction

Journal of Neurochemistry

Volumn 114, Issue 4, 2010, Pages 1193-1204

  Pivtoraiko, Violetta N ^a   Harrington, Adam J ^b   Mader, Burton J ^a   Luker, Austin M ^a   Caldwell, Guy A ^b,c   Caldwell, Kim A ^b,c   Roth, Kevin A ^a   Shacka, John J ^a,d  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d SC 915 ^*  (United States)

Author keywords

synuclein; autophagy; bafilomycin; cathepsin D; lysosome; Parkinson's Disease

Indexed keywords

ALPHA SYNUCLEIN; AMODIAQUINE; ASPARTIC PROTEINASE; BAFILOMYCIN A1; BAFILOMYCIN B1; CATHEPSIN D; CHLOROQUINE; DOPAMINE; HYDROXYCHLOROQUINE; OLIGOMER; STAUROSPORINE; BAFILOMYCIN A; MACROLIDE;

ARTICLE; AUTOPHAGY; CAENORHABDITIS ELEGANS; CELL DEATH; CELL VACUOLE; DEGENERATIVE DISEASE; DOPAMINERGIC NERVE CELL; DOSE RESPONSE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LYSOSOME; NERVE CELL NECROSIS; NEUROBLASTOMA CELL; NEUROPROTECTION; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SPECIES; WILD TYPE; ANIMAL; CELL PROTECTION; DISEASE COURSE; DRUG EFFECTS; METABOLISM; NERVE CELL; NERVE DEGENERATION; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CAENORHABDITIS ELEGANS;

ANIMALS; AUTOPHAGY; CAENORHABDITIS ELEGANS; CELL LINE, TUMOR; CYTOPROTECTION; DISEASE PROGRESSION; HUMANS; LYSOSOMES; MACROLIDES; NERVE DEGENERATION; NEURONS; SIGNAL TRANSDUCTION;

EID: 77954715959     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06838.x     Document Type: Article

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