Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K/Akt/mTOR pathway in human non-small cell lung cancer cells

Cancer Letters

Volumn 344, Issue 2, 2014, Pages 239-259

  Li, Yan Cong ^a,b   He, Shu Ming ^a   He, Zhi Xu ^c   Li, Minghua ^b   Yang, Yinxue ^d   Pang, Jian Xin ^a   Zhang, Xueji ^e   Chow, Kevin ^b   Zhou, Qingyu ^b   Duan, Wei ^f   Zhou, Zhi Wei ^b   Yang, Tianxin ^g   Huang, Gui Hua ^h   Liu, Aibing ⁱ   Qiu, Jia Xuan ^j   Liu, Jun Ping ^k,l,m   Zhou, Shu Feng ^b,c  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c GUIZHOU MEDICAL UNIVERSITY   (China)

^d NINGXIA MEDICAL UNIVERSITY   (China)

^e UNIVERSITY OF SCIENCE AND TECHNOLOGY BEIJING   (China)

^f DEAKIN UNIVERSITY   (Australia)

^g VETERANS AFFAIRS MEDICAL CENTER   (United States)

^h THE FIRST AFFILIATED HOSPITAL OF GUANGXI UNIVERSITY OF CHINESE MEDICINE   (China)

ⁱ GENERAL HOSPITAL OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

^j NANCHANG UNIVERSITY   (China)

^k HANGZHOU NORMAL UNIVERSITY   (China)

^l MONASH UNIVERSITY   (Australia)

^m UNIVERSITY OF MELBOURNE   (Australia)

more..

Author keywords

Apoptosis; Autophagy; Non small cell lung cancer; PI3K Akt mTOR; Plumbagin

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; PLUMBAGIN; REACTIVE OXYGEN METABOLITE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; DRUG MECHANISM; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; M PHASE CELL CYCLE CHECKPOINT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

APOPTOSIS; AUTOPHAGY; NON-SMALL-CELL LUNG CANCER; PI3K/AKT/MTOR; PLUMBAGIN;

APOPTOSIS; AUTOPHAGY; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; HUMANS; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; NAPHTHOQUINONES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; TOR SERINE-THREONINE KINASES;

EID: 84893655803     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.11.001     Document Type: Article

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