Autophagy-related gene 7 (ATG7) and reactive oxygen species/extracellular signal-regulated kinase regulate tetrandrine-induced autophagy in human hepatocellular carcinoma

Journal of Biological Chemistry

Volumn 287, Issue 42, 2012, Pages 35576-35588

  Gong, Ke ^a   Chen, Chao ^a   Zhan, Yao ^a   Chen, Yan ^a   Huang, Zebo ^a   Li, Wenhua ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITUMOR EFFECT; AUTOPHAGY; CANCER CHEMOTHERAPEUTIC AGENTS; CHEMOTHERAPEUTIC AGENTS; CHINESE MEDICINAL HERBS; ELEGANS; FLUORESCENCE PATTERNS; HEPATOCELLULAR CARCINOMA; HIGH CONCENTRATION; IN-VITRO; IN-VIVO; LIVER CANCER CELLS; LOW DOSE; MAP KINASE; MITOCHONDRIAL DYSFUNCTION; MUSCLE CELL; REACTIVE OXYGEN SPECIES; SIGNAL-REGULATED KINASE; SIGNALING PATHWAYS; TETRANDRINE; TUMOR XENOGRAFTS;

CELL DEATH; ENZYMES; OXYGEN;

GENE EXPRESSION;

AUTOPHAGY PROTEIN 7; CASPASE 3; CASPASE 8; CYTOCHROME C; IMMUNOGLOBULIN LIGHT CHAIN; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; REACTIVE OXYGEN METABOLITE; TETRANDRINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOLYSOSOME; AUTOPHAGY; CANCER CELL; CELL VACUOLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME REGULATION; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; LOW DRUG DOSE; MEMBRANE DEPOLARIZATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AUTOPHAGY; BENZYLISOQUINOLINES; CARCINOMA, HEPATOCELLULAR; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; NEOPLASM PROTEINS; REACTIVE OXYGEN SPECIES; STEPHANIA TETRANDRA; TRANSCRIPTION, GENETIC; UBIQUITIN-ACTIVATING ENZYMES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84867430967     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.370585     Document Type: Article

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