Chloroquine in cancer therapy: A double-edged sword of autophagy

Cancer Research

Volumn 73, Issue 1, 2013, Pages 3-7

  Kimura, Tomonori ^a   Takabatake, Yoshitsugu ^a   Takahashi, Atsushi ^a   Isaka, Yoshitaka ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; ANTINEOPLASTIC AGENT; BAFILOMYCIN A1; BECLIN 1; CELL PROTEIN; CHLOROQUINE; CISPLATIN; CREATININE; DAUNORUBICIN; DOXORUBICIN; PEPSTAIN A; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; AGING; ANTIMALARIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ATG7 GENE; AUTOIMMUNE DISEASE; AUTOPHAGY; BECLIN 1 GENE; BLOOD VESSEL INJURY; BONE MARROW DEPRESSION; BRAIN; CANCER CELL; CANCER CHEMOTHERAPY; CANCER COMBINATION CHEMOTHERAPY; CANCER CONTROL; CANCER INHIBITION; CANCER RADIOTHERAPY; CARDIOTOXICITY; CELL CYCLE; CELL CYCLE ARREST; CELL DAMAGE; CELL ORGANELLE; CELL SURVIVAL; CREATININE BLOOD LEVEL; DISEASE EXACERBATION; DNA DAMAGE; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG DOSE REDUCTION; DRUG EXCRETION; DRUG INDUCED DISEASE; DRUG INDUCED HEADACHE; DRUG MECHANISM; DRUG MEGADOSE; DRUG MONITORING; DRUG POTENTIATION; DRUG SENSITIVITY; DRUG SENSITIZATION; DRUG TARGETING; DRUG TOLERABILITY; ECG ABNORMALITY; ENDOCYTOSIS; ENERGY RESOURCE; ENERGY YIELD; GASTROINTESTINAL SYMPTOM; GENE; GENE DISRUPTION; GENE FUNCTION; GENE PRODUCT; GLUCOSE TRANSPORT; GLYCOLYSIS; HEART; HEMATOPOIETIC STEM CELL; HOMEOSTASIS; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; IN VIVO STUDY; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; LIVER; LIVER ADENOMA; LOW DRUG DOSE; MALARIA; MALIGNANT NEOPLASTIC DISEASE; METASTASIS POTENTIAL; NEPHROTOXICITY; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PRURITUS; RENAL PROTECTION; REVIEW; RISK FACTOR; TREATMENT OUTCOME; TUMOR MICROENVIRONMENT; TUMOR PROMOTION; VISUAL DISORDER;

ANIMALS; ANTINEOPLASTIC AGENTS; AUTOPHAGY; CHLOROQUINE; HUMANS; KIDNEY; NEOPLASMS;

EID: 84871940714     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-2464     Document Type: Review

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