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Volumn 5, Issue 1, 2015, Pages

Tetrandrine is a potent cell autophagy agonist via activated intracellular reactive oxygen species

Author keywords

Autophagy; Reactive oxygen species; Tetrandrine

Indexed keywords


EID: 85027947666     PISSN: None     EISSN: 20453701     Source Type: Journal    
DOI: 10.1186/2045-3701-5-4     Document Type: Article
Times cited : (43)

References (48)
  • 2
    • 84891747382 scopus 로고    scopus 로고
    • The machinery of macroautophagy
    • Feng Y, He D, Yao Z, Klionsky DJ: The machinery of macroautophagy. Cell Res 2014, 24:24-41. 10.1038/cr.2013.168
    • (2014) Cell Res , vol.24 , pp. 24-41
    • Feng, Y.1    He, D.2    Yao, Z.3    Klionsky, D.J.4
  • 3
    • 84888161072 scopus 로고    scopus 로고
    • Therapeutic targeting of autophagy in disease: biology and pharmacology
    • Cheng Y, Ren X, Hait WN, Yang JM: Therapeutic targeting of autophagy in disease: biology and pharmacology. Pharmacol Rev 2013, 65:1162-97. 10.1124/pr.112.007120
    • (2013) Pharmacol Rev , vol.65 , pp. 1162-1197
    • Cheng, Y.1    Ren, X.2    Hait, W.N.3    Yang, J.M.4
  • 4
    • 57849136841 scopus 로고    scopus 로고
    • Autophagy: principles and significance in health and disease
    • Todde V, Veenhuis M, van der Klei IJ: Autophagy: principles and significance in health and disease. Biochim Biophys Acta 2009, 1792:3-13. 10.1016/j.bbadis.2008.10.016
    • (2009) Biochim Biophys Acta , vol.1792 , pp. 3-13
    • Todde, V.1    Veenhuis, M.2    van der Klei, I.J.3
  • 5
    • 84878775231 scopus 로고    scopus 로고
    • Lipofuscin: formation, effects and role of macroautophagy
    • Hohn A, Grune T: Lipofuscin: formation, effects and role of macroautophagy. Redox Biol 2013, 1:140-4. 10.1016/j.redox.2013.01.006
    • (2013) Redox Biol , vol.1 , pp. 140-144
    • Hohn, A.1    Grune, T.2
  • 6
    • 79955052480 scopus 로고    scopus 로고
    • Tuning flux: autophagy as a target of heart disease therapy
    • Xie M, Morales CR, Lavandero S, Hill JA: Tuning flux: autophagy as a target of heart disease therapy. Curr Opin Cardiol 2011, 26:216-22. 10.1097/HCO.0b013e328345980a
    • (2011) Curr Opin Cardiol , vol.26 , pp. 216-222
    • Xie, M.1    Morales, C.R.2    Lavandero, S.3    Hill, J.A.4
  • 7
    • 79951847989 scopus 로고    scopus 로고
    • Principles and current strategies for targeting autophagy for cancer treatment
    • Amaravadi RK: Principles and current strategies for targeting autophagy for cancer treatment. Clin Cancer Res 2011, 17:654-66. 10.1158/1078-0432.CCR-10-2634
    • (2011) Clin Cancer Res , vol.17 , pp. 654-666
    • Amaravadi, R.K.1
  • 8
    • 84887486465 scopus 로고    scopus 로고
    • Survival or death: disequilibrating the oncogenic and tumor suppressive autophagy in cancer
    • Liu B, Wen X, Cheng Y: Survival or death: disequilibrating the oncogenic and tumor suppressive autophagy in cancer. Cell Death Dis 2013, 4:e892. 10.1038/cddis.2013.422
    • (2013) Cell Death Dis , vol.4 , pp. e892
    • Liu, B.1    Wen, X.2    Cheng, Y.3
  • 9
    • 84884820821 scopus 로고    scopus 로고
    • Autophagy regulation and its role in cancer
    • Lorin S, Hamai A, Mehrpour M, Codogno P: Autophagy regulation and its role in cancer. Semin Cancer Biol 2013, 23:361-79. 10.1016/j.semcancer.2013.06.007
    • (2013) Semin Cancer Biol , vol.23 , pp. 361-379
    • Lorin, S.1    Hamai, A.2    Mehrpour, M.3    Codogno, P.4
  • 10
    • 79957883170 scopus 로고    scopus 로고
    • The multiple roles of autophagy in cancer
    • Rosenfeldt MT, Ryan KM: The multiple roles of autophagy in cancer. Carcinogenesis 2011, 32:955-63. 10.1093/carcin/bgr031
    • (2011) Carcinogenesis , vol.32 , pp. 955-963
    • Rosenfeldt, M.T.1    Ryan, K.M.2
  • 11
    • 84866312155 scopus 로고    scopus 로고
    • Pharmacological modulation of autophagy during cardiac stress
    • Sciarretta S, Zhai P, Volpe M, Sadoshima J: Pharmacological modulation of autophagy during cardiac stress. J Cardiovasc Pharmacol 2012, 60:235-41. 10.1097/FJC.0b013e3182575f61
    • (2012) J Cardiovasc Pharmacol , vol.60 , pp. 235-241
    • Sciarretta, S.1    Zhai, P.2    Volpe, M.3    Sadoshima, J.4
  • 12
    • 84877630830 scopus 로고    scopus 로고
    • Autophagy modulation as a target for anticancer drug discovery
    • Li X, Xu HL, Liu YX, An N, Zhao S, Bao JK: Autophagy modulation as a target for anticancer drug discovery. Acta Pharmacol Sin 2013, 34:612-24. 10.1038/aps.2013.23
    • (2013) Acta Pharmacol Sin , vol.34 , pp. 612-624
    • Li, X.1    Xu, H.L.2    Liu, Y.X.3    An, N.4    Zhao, S.5    Bao, J.K.6
  • 13
    • 77956363593 scopus 로고    scopus 로고
    • Autophagic pathways as new targets for cancer drug development
    • Liu B, Cheng Y, Liu Q, Bao JK, Yang JM: Autophagic pathways as new targets for cancer drug development. Acta Pharmacol Sin 2010, 31:1154-64. 10.1038/aps.2010.118
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 1154-1164
    • Liu, B.1    Cheng, Y.2    Liu, Q.3    Bao, J.K.4    Yang, J.M.5
  • 14
    • 0023377276 scopus 로고
    • Bisbenzylisoquinoline alkaloids
    • Schiff PLJ: Bisbenzylisoquinoline alkaloids. J Nat Prod 1987, 50:529-99. 10.1021/np50052a001
    • (1987) J Nat Prod , vol.50 , pp. 529-599
    • Schiff, P.L.J.1
  • 15
    • 1942485431 scopus 로고    scopus 로고
    • Chinese herbs as immunomodulators and potential disease-modifying antirheumatic drugs in autoimmune disorders
    • Ho LJLJ: Chinese herbs as immunomodulators and potential disease-modifying antirheumatic drugs in autoimmune disorders. Curr Drug Metab 2004, 5:181-92. 10.2174/1389200043489081
    • (2004) Curr Drug Metab , vol.5 , pp. 181-192
    • Ho, L.J.L.J.1
  • 16
    • 84855167212 scopus 로고    scopus 로고
    • Efficacy of tetrandrine on lowering intraocular pressure in animal model with ocular hypertension
    • Huang PXY, Wei R, Li H, Tang Y, Liu J, Zhang SS, et al.: Efficacy of tetrandrine on lowering intraocular pressure in animal model with ocular hypertension. J Glaucoma 2011,20(3):183-8. 10.1097/IJG.0b013e3181d7882a
    • (2011) J Glaucoma , vol.20 , Issue.3 , pp. 183-188
    • Huang, P.X.Y.1    Wei, R.2    Li, H.3    Tang, Y.4    Liu, J.5    Zhang, S.S.6
  • 17
    • 84875538417 scopus 로고    scopus 로고
    • Effective treatment with a tetrandrine/chloroquine combination for chloroquine-resistant falciparum malaria in Aotus monkeys
    • Ye ZVDK, Rossan RN: Effective treatment with a tetrandrine/chloroquine combination for chloroquine-resistant falciparum malaria in Aotus monkeys. Malar J 2013, 12:117. 10.1186/1475-2875-12-117
    • (2013) Malar J , vol.12 , pp. 117
    • Ye, Z.V.D.K.1    Rossan, R.N.2
  • 18
    • 79951931336 scopus 로고    scopus 로고
    • Diabetes is an inflammatory disease: evidence from traditional Chinese medicines
    • Xie WDL: Diabetes is an inflammatory disease: evidence from traditional Chinese medicines. Diabetes Obes Metab 2011,13(4):289-301. 10.1111/j.1463-1326.2010.01336.x
    • (2011) Diabetes Obes Metab , vol.13 , Issue.4 , pp. 289-301
    • Xie, W.D.L.1
  • 20
    • 0034528591 scopus 로고    scopus 로고
    • Cardiovascular actions of Radix Stephaniae Tetrandrae: a comparison with its main component, tetrandrine
    • Tak-Ming Wong SW, Xiao-Chun YU, Hong-Yu: Cardiovascular actions of Radix Stephaniae Tetrandrae: a comparison with its main component, tetrandrine. Acla Phamacvl Si 2000, 21:1083-8.
    • (2000) Acla Phamacvl Si , vol.21 , pp. 1083-1088
    • Tak-Ming Wong, S.W.1    Xiao-Chun, Y.U.2    Hong-Yu, Y.U.3
  • 22
    • 80053273291 scopus 로고    scopus 로고
    • The potential of tetrandrine as a protective agent for ischemic stroke
    • Chen Y, Tsai YH, Tseng SH: The potential of tetrandrine as a protective agent for ischemic stroke. Molecules 2011, 16:8020-32. 10.3390/molecules16098020
    • (2011) Molecules , vol.16 , pp. 8020-8032
    • Chen, Y.1    Tsai, Y.H.2    Tseng, S.H.3
  • 23
    • 0034757747 scopus 로고    scopus 로고
    • Anti-inflammatory effects of the partially purified extract of radix Stephaniae tetrandrae: comparative studies of its active principles tetrandrine and fangchinoline on human polymorphonuclear leukocyte functions
    • Shen YCCC, Chiou WF, Chen CF: Anti-inflammatory effects of the partially purified extract of radix Stephaniae tetrandrae: comparative studies of its active principles tetrandrine and fangchinoline on human polymorphonuclear leukocyte functions. Mol Pharmacol 2001, 60:1083-90.
    • (2001) Mol Pharmacol , vol.60 , pp. 1083-1090
    • Shen, Y.C.C.C.1    Chiou, W.F.2    Chen, C.F.3
  • 24
    • 0030909069 scopus 로고    scopus 로고
    • Cytotoxicity to macrophages of tetrandrine, an antisilicosis alkaloid, accompanied by an overproduction of prostaglandins
    • Pang LHJ: Cytotoxicity to macrophages of tetrandrine, an antisilicosis alkaloid, accompanied by an overproduction of prostaglandins. Biochem Pharmacol Rev 1997, 53:773-82. 10.1016/S0006-2952(96)00817-9
    • (1997) Biochem Pharmacol Rev , vol.53 , pp. 773-782
    • Pang, L.H.J.1
  • 25
    • 84899068917 scopus 로고    scopus 로고
    • Effects of tetrandrine on glioma cell malignant phenotype via inhibition of ADAM17
    • Wu ZWG, Xu S, Li Y, Tian Y, Niu H, Yuan F, et al.: Effects of tetrandrine on glioma cell malignant phenotype via inhibition of ADAM17. Tumour Biol 2014, 35:2205-10. 10.1007/s13277-013-1293-y
    • (2014) Tumour Biol , vol.35 , pp. 2205-2210
    • Wu, Z.W.G.1    Xu, S.2    Li, Y.3    Tian, Y.4    Niu, H.5    Yuan, F.6
  • 26
    • 84897406550 scopus 로고    scopus 로고
    • Tetrandrine blocks autophagic flux and induces apoptosis via energetic impairment in cancer cells
    • Qiu W, Su M, Xie F, Ai J, Ren Y, Zhang J, et al.: Tetrandrine blocks autophagic flux and induces apoptosis via energetic impairment in cancer cells. Cell Death Dis 2014, 5:e1123. 10.1038/cddis.2014.84
    • (2014) Cell Death Dis , vol.5 , pp. e1123
    • Qiu, W.1    Su, M.2    Xie, F.3    Ai, J.4    Ren, Y.5    Zhang, J.6
  • 27
    • 84893827975 scopus 로고    scopus 로고
    • Tetrandrine induces apoptosis and triggers a caspase cascade in U2-OS and MG-63 cells through the intrinsic and extrinsic pathways
    • Li-Jiang Tao X-DZ, Shen C-C, Liang C-Z, Liu B, Tao Y, Tao H-M: Tetrandrine induces apoptosis and triggers a caspase cascade in U2-OS and MG-63 cells through the intrinsic and extrinsic pathways. Mol Med Rep 2013, 9:345-9.
    • (2013) Mol Med Rep , vol.9 , pp. 345-349
    • Li-Jiang Tao, X.-D.Z.1    Shen, C.-C.2    Liang, C.-Z.3    Liu, B.4    Tao, Y.5    Tao, H.-M.6
  • 28
    • 84885027804 scopus 로고    scopus 로고
    • Tetrandrine induces mitochondria-mediated apoptosis in human gastric cancer BGC-823 cells
    • Rong Qin HS, Cao Y, Fang Y, Li H, Chen Q, Xu W: Tetrandrine induces mitochondria-mediated apoptosis in human gastric cancer BGC-823 cells. PLoS One 2013, 8:e76486. 10.1371/journal.pone.0076486
    • (2013) PLoS One , vol.8 , pp. e76486
    • Rong Qin, H.S.1    Cao, Y.2    Fang, Y.3    Li, H.4    Chen, Q.5    Xu, W.6
  • 29
    • 79959757676 scopus 로고    scopus 로고
    • Tetrandrine induces apoptosis by activating reactive oxygen species and repressing Akt activity in human hepatocellular carcinoma
    • Liu C, Gong K, Mao X, Li W: Tetrandrine induces apoptosis by activating reactive oxygen species and repressing Akt activity in human hepatocellular carcinoma. Int J Cancer 2011, 129:1519-31. 10.1002/ijc.25817
    • (2011) Int J Cancer , vol.129 , pp. 1519-1531
    • Liu, C.1    Gong, K.2    Mao, X.3    Li, W.4
  • 30
    • 84867430967 scopus 로고    scopus 로고
    • Autophagy-related gene 7 (ATG7) and reactive oxygen species/extracellular signal-regulated kinase regulate tetrandrine-induced autophagy in human hepatocellular carcinoma
    • Gong K, Chen C, Zhan Y, Chen Y, Huang Z, Li W: Autophagy-related gene 7 (ATG7) and reactive oxygen species/extracellular signal-regulated kinase regulate tetrandrine-induced autophagy in human hepatocellular carcinoma. J Biol Chem 2012, 287:35576-88. 10.1074/jbc.M112.370585
    • (2012) J Biol Chem , vol.287 , pp. 35576-35588
    • Gong, K.1    Chen, C.2    Zhan, Y.3    Chen, Y.4    Huang, Z.5    Li, W.6
  • 31
    • 84881113732 scopus 로고    scopus 로고
    • Synergistic antitumour activity of sorafenib in combination with tetrandrine is mediated by reactive oxygen species (ROS)/Akt signaling
    • Wan J, Liu T, Mei L, Li J, Gong K, Yu C, et al.: Synergistic antitumour activity of sorafenib in combination with tetrandrine is mediated by reactive oxygen species (ROS)/Akt signaling. Br J Cancer 2013, 109:342-50. 10.1038/bjc.2013.334
    • (2013) Br J Cancer , vol.109 , pp. 342-350
    • Wan, J.1    Liu, T.2    Mei, L.3    Li, J.4    Gong, K.5    Yu, C.6
  • 32
    • 69349088142 scopus 로고    scopus 로고
    • Mitophagy
    • Tolkovsky AM: Mitophagy. Biochim Biophys Acta 2009, 1793:1508-15. 10.1016/j.bbamcr.2009.03.002
    • (2009) Biochim Biophys Acta , vol.1793 , pp. 1508-1515
    • Tolkovsky, A.M.1
  • 33
    • 84893752695 scopus 로고    scopus 로고
    • Autophagy and enhanced chemosensitivity in experimental pancreatic cancers induced by noninvasive radiofrequency field treatment
    • Koshkina NVBK, Palalon F, Curley SA: Autophagy and enhanced chemosensitivity in experimental pancreatic cancers induced by noninvasive radiofrequency field treatment. Cancer 2014, 120:480-91. 10.1002/cncr.28453
    • (2014) Cancer , vol.120 , pp. 480-491
    • Koshkina, N.V.B.K.1    Palalon, F.2    Curley, S.A.3
  • 34
    • 84905740364 scopus 로고    scopus 로고
    • The checkpoint 1 kinase inhibitor LY2603618 induces cell cycle arrest, DNA damage response and autophagy in cancer cells
    • Wang FZFH, Cui YJ, Sun YK, Li ZM, Wang XY, Yang XY, et al.: The checkpoint 1 kinase inhibitor LY2603618 induces cell cycle arrest, DNA damage response and autophagy in cancer cells. Apoptosis 2014, 19:1389-98. 10.1007/s10495-014-1010-3
    • (2014) Apoptosis , vol.19 , pp. 1389-1398
    • Wang, F.Z.F.H.1    Cui, Y.J.2    Sun, Y.K.3    Li, Z.M.4    Wang, X.Y.5    Yang, X.Y.6
  • 35
    • 34147193472 scopus 로고    scopus 로고
    • Autophagy and cancer
    • Levine B: Autophagy and cancer. Nature 2007, 446:745-7. 10.1038/446745a
    • (2007) Nature , vol.446 , pp. 745-747
    • Levine, B.1
  • 36
    • 84949117662 scopus 로고    scopus 로고
    • ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death in human malignant glioma
    • Thayyullathil F, Rahman A, Pallichankandy S, Patel M, Galadari S: ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death in human malignant glioma. FEBS Open Bio 2014, 4:763-76.
    • (2014) FEBS Open Bio , vol.4 , pp. 763-776
    • Thayyullathil, F.1    Rahman, A.2    Pallichankandy, S.3    Patel, M.4    Galadari, S.5
  • 37
    • 84907587227 scopus 로고    scopus 로고
    • Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy
    • Changou CACY, Xing L, Yen Y, Chuang FY, Cheng RH, Bold RJ, et al.: Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy. Proc Natl Acad Sci U S A 2014, 111:14147-52. 10.1073/pnas.1404171111
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 14147-14152
    • Changou, C.A.C.Y.1    Xing, L.2    Yen, Y.3    Chuang, F.Y.4    Cheng, R.H.5    Bold, R.J.6
  • 38
    • 84883827034 scopus 로고    scopus 로고
    • Calyxin Y induces hydrogen peroxide-dependent autophagy and apoptosis via JNK activation in human non-small cell lung cancer NCI-H460 cells
    • Zhang CYL, Wang XB, Wang JS, Geng YD, Yang CS, Kong LY: Calyxin Y induces hydrogen peroxide-dependent autophagy and apoptosis via JNK activation in human non-small cell lung cancer NCI-H460 cells. Cancer Lett 2013, 340:51-62. 10.1016/j.canlet.2013.06.021
    • (2013) Cancer Lett , vol.340 , pp. 51-62
    • Zhang, C.Y.L.1    Wang, X.B.2    Wang, J.S.3    Geng, Y.D.4    Yang, C.S.5    Kong, L.Y.6
  • 39
    • 84903882101 scopus 로고    scopus 로고
    • An autophagic switch in the response of tumor cells to radiation and chemotherapy
    • Gewirtz DA: An autophagic switch in the response of tumor cells to radiation and chemotherapy. Biochem Pharmacol Rev 2014, 90:208-11. 10.1016/j.bcp.2014.05.016
    • (2014) Biochem Pharmacol Rev , vol.90 , pp. 208-211
    • Gewirtz, D.A.1
  • 40
    • 84863499969 scopus 로고    scopus 로고
    • P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells
    • Zhan Y, Gong K, Chen C, Wang H, Li W: P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells. Free Radic Biol Med 2012, 53:532-43. 10.1016/j.freeradbiomed.2012.05.018
    • (2012) Free Radic Biol Med , vol.53 , pp. 532-543
    • Zhan, Y.1    Gong, K.2    Chen, C.3    Wang, H.4    Li, W.5
  • 41
    • 84905841277 scopus 로고    scopus 로고
    • Methylation silencing of ULK2, an autophagy gene, is essential for astrocyte transformation and tumor growth
    • Shukla SPI, Patil V, Shwetha SD, Hegde AS, Chandramouli BA, Arivazhagan A, et al.: Methylation silencing of ULK2, an autophagy gene, is essential for astrocyte transformation and tumor growth. J Biol Chem 2014, 289:22306-18. 10.1074/jbc.M114.567032
    • (2014) J Biol Chem , vol.289 , pp. 22306-22318
    • Shukla, S.P.I.1    Patil, V.2    Shwetha, S.D.3    Hegde, A.S.4    Chandramouli, B.A.5    Arivazhagan, A.6
  • 43
    • 84902011359 scopus 로고    scopus 로고
    • Tetrandrine and fangchinoline, bisbenzylisoquinoline alkaloids from Stephania tetrandra can reverse multidrug resistance by inhibiting P-glycoprotein activity in multidrug resistant human cancer cells
    • Sun YFWM: Tetrandrine and fangchinoline, bisbenzylisoquinoline alkaloids from Stephania tetrandra can reverse multidrug resistance by inhibiting P-glycoprotein activity in multidrug resistant human cancer cells. Phytomedicine 2014, 21:1110-9. 10.1016/j.phymed.2014.04.029
    • (2014) Phytomedicine , vol.21 , pp. 1110-1119
    • Sun, Y.F.W.M.1
  • 44
    • 84860525972 scopus 로고    scopus 로고
    • Glucose deprivation in tuberous sclerosis complex-related tumors
    • Jiang X, Kenerson HL, Yeung RS: Glucose deprivation in tuberous sclerosis complex-related tumors. Cell Biosci 2011, 1:34. 10.1186/2045-3701-1-34
    • (2011) Cell Biosci , vol.1 , pp. 34
    • Jiang, X.1    Kenerson, H.L.2    Yeung, R.S.3
  • 45
    • 84897415977 scopus 로고    scopus 로고
    • Suppression of autophagy by chloroquine sensitizes 5-fluorouracil-mediated cell death in gallbladder carcinoma cells
    • Xiao Liang JT, Liang YL, Jin RA, Cai XJ: Suppression of autophagy by chloroquine sensitizes 5-fluorouracil-mediated cell death in gallbladder carcinoma cells. Cell Biosci 2014, 4:10. 10.1186/2045-3701-4-10
    • (2014) Cell Biosci , vol.4 , pp. 10
    • Xiao Liang, J.T.1    Liang, Y.L.2    Jin, R.A.3    Cai, X.J.4
  • 48


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