-
1
-
-
0025881195
-
Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: Evidence for a neuronal-specific isoform
-
1849734 10.1021/bi00229a001 1:CAS:528:DyaK3MXhsl2ntb8%3D
-
Mayer RE, Hendrix P, Cron P et al (1991) Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform. Biochemistry 30:3589-3597
-
(1991)
Biochemistry
, vol.30
, pp. 3589-3597
-
-
Mayer, R.E.1
Hendrix, P.2
Cron, P.3
-
2
-
-
0033153258
-
Brain protein serine/threonine phosphatases
-
10395578 10.1016/S0959-4388(99)80049-X 1:CAS:528:DyaK1MXktVyksr0%3D
-
Price NE, Mumby MC (1999) Brain protein serine/threonine phosphatases. Curr Opin Neurobiol 9:336-342
-
(1999)
Curr Opin Neurobiol
, vol.9
, pp. 336-342
-
-
Price, N.E.1
Mumby, M.C.2
-
3
-
-
0036830613
-
Overexpression of the protein phosphatase 2A regulatory subunit Bgamma promotes neuronal differentiation by activating the MAP kinase (MAPK) cascade
-
12191994 10.1074/jbc.M203767200 1:CAS:528:DC%2BD38XotF2hurc%3D
-
Strack S (2002) Overexpression of the protein phosphatase 2A regulatory subunit Bgamma promotes neuronal differentiation by activating the MAP kinase (MAPK) cascade. J Biol Chem 277:41525-41532
-
(2002)
J Biol Chem
, vol.277
, pp. 41525-41532
-
-
Strack, S.1
-
4
-
-
0030684714
-
Protein serine/threonine phosphatase 1 and 2A associate with and dephosphorylate neurofilaments
-
9387859 10.1016/S0169-328X(97)00117-4 1:CAS:528:DyaK2sXlsleqt7s%3D
-
Strack S, Westphal RS, Colbran RJ, Ebner FF, Wadzinski BE (1997) Protein serine/threonine phosphatase 1 and 2A associate with and dephosphorylate neurofilaments. Brain Res Mol Brain Res 49:15-28
-
(1997)
Brain Res Mol Brain Res
, vol.49
, pp. 15-28
-
-
Strack, S.1
Westphal, R.S.2
Colbran, R.J.3
Ebner, F.F.4
Wadzinski, B.E.5
-
5
-
-
0032536810
-
Brain protein phosphatase 2A: Developmental regulation and distinct cellular and subcellular localization by B subunits
-
9514514 10.1002/(SICI)1096-9861(19980323)392:4<515: AID-CNE8>3.0.CO;2-3 1:CAS:528:DyaK1cXhsFSls7k%3D
-
Strack S, Zaucha JA, Ebner FF, Colbran RJ, Wadzinski BE (1998) Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits. J Comp Neurol 392:515-527
-
(1998)
J Comp Neurol
, vol.392
, pp. 515-527
-
-
Strack, S.1
Zaucha, J.A.2
Ebner, F.F.3
Colbran, R.J.4
Wadzinski, B.E.5
-
6
-
-
0032703317
-
Cloning and characterization of B delta, a novel regulatory subunit of protein phosphatase 2A
-
10556517 10.1016/S0014-5793(99)01377-0 1:CAS:528:DyaK1MXntVChtLk%3D
-
Strack S, Chang D, Zaucha JA, Colbran RJ, Wadzinski BE (1999) Cloning and characterization of B delta, a novel regulatory subunit of protein phosphatase 2A. FEBS Lett 460:462-466
-
(1999)
FEBS Lett
, vol.460
, pp. 462-466
-
-
Strack, S.1
Chang, D.2
Zaucha, J.A.3
Colbran, R.J.4
Wadzinski, B.E.5
-
7
-
-
0035503214
-
SCA12: An unusual mutation leads to an unusual spinocerebellar ataxia
-
11719278 10.1016/S0361-9230(01)00596-2 1:CAS:528:DC%2BD3MXosFOjsL8%3D
-
Holmes SE, Hearn EO, Ross CA, Margolis RL (2001) SCA12: an unusual mutation leads to an unusual spinocerebellar ataxia. Brain Res Bull 56:397-403
-
(2001)
Brain Res Bull
, vol.56
, pp. 397-403
-
-
Holmes, S.E.1
Hearn, E.O.2
Ross, C.A.3
Margolis, R.L.4
-
8
-
-
0344962346
-
Why is SCA12 different from other SCAs?
-
14526180 10.1159/000072854 1:CAS:528:DC%2BD3sXnslarsL8%3D
-
Holmes SE, O'Hearn E, Margolis RL (2003) Why is SCA12 different from other SCAs? Cytogenet Genome Res 100:189-197
-
(2003)
Cytogenet Genome Res
, vol.100
, pp. 189-197
-
-
Holmes, S.E.1
O'Hearn, E.2
Margolis, R.L.3
-
10
-
-
0032727249
-
Expansion of a novel CAG trinucleotide repeat in the 5′ region of PPP2R2B is associated with SCA12
-
10581021 10.1038/70493 1:STN:280:DC%2BD3c%2FkslOlsQ%3D%3D
-
Holmes SE, O'Hearn EE, McInnis MG et al (1999) Expansion of a novel CAG trinucleotide repeat in the 5′ region of PPP2R2B is associated with SCA12. Nat Genet 23:391-392
-
(1999)
Nat Genet
, vol.23
, pp. 391-392
-
-
Holmes, S.E.1
O'Hearn, E.E.2
McInnis, M.G.3
-
11
-
-
0032978487
-
Vimentin dephosphorylation by protein phosphatase 2A is modulated by the targeting subunit B55
-
10359611 1:CAS:528:DyaK1MXjvVamtL8%3D
-
Turowski P, Myles T, Hemmings BA, Fernandez A, Lamb NJ (1999) Vimentin dephosphorylation by protein phosphatase 2A is modulated by the targeting subunit B55. Mol Biol Cell 10:1997-2015
-
(1999)
Mol Biol Cell
, vol.10
, pp. 1997-2015
-
-
Turowski, P.1
Myles, T.2
Hemmings, B.A.3
Fernandez, A.4
Lamb, N.J.5
-
12
-
-
0028142259
-
Drosophila mutants in the 55 kDa regulatory subunit of protein phosphatase 2A show strongly reduced ability to dephosphorylate substrates of p34cdc2
-
7844174 1:CAS:528:DyaK2MXps1Srsw%3D%3D
-
Mayer-Jaekel RE, Ohkura H, Ferrigno P et al (1994) Drosophila mutants in the 55 kDa regulatory subunit of protein phosphatase 2A show strongly reduced ability to dephosphorylate substrates of p34cdc2. J Cell Sci 107(Pt 9):2609-2616
-
(1994)
J Cell Sci
, vol.107
, Issue.PART 9
, pp. 2609-2616
-
-
Mayer-Jaekel, R.E.1
Ohkura, H.2
Ferrigno, P.3
-
13
-
-
0027772552
-
The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation
-
8252625 10.1016/0092-8674(93)90533-V 1:CAS:528:DyaK2cXnsVCluw%3D%3D
-
Sontag E, Fedorov S, Kamibayashi C, Robbins D, Cobb M, Mumby M (1993) The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation. Cell 75:887-897
-
(1993)
Cell
, vol.75
, pp. 887-897
-
-
Sontag, E.1
Fedorov, S.2
Kamibayashi, C.3
Robbins, D.4
Cobb, M.5
Mumby, M.6
-
14
-
-
27744512550
-
Distinct protein phosphatase 2A heterotrimers modulate growth factor signaling to extracellular signal-regulated kinases and Akt
-
16129692 10.1074/jbc.M506986200
-
Van Kanegan MJ, Adams DG, Wadzinski BE, Strack S (2005) Distinct protein phosphatase 2A heterotrimers modulate growth factor signaling to extracellular signal-regulated kinases and Akt. J Biol Chem 280:36029-36036
-
(2005)
J Biol Chem
, vol.280
, pp. 36029-36036
-
-
Van Kanegan, M.J.1
Adams, D.G.2
Wadzinski, B.E.3
Strack, S.4
-
15
-
-
60249095382
-
The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bβ2 antagonizes neuronal survival by promoting mitochondrial fission
-
18940801 10.1074/jbc.M800989200 1:CAS:528:DC%2BD1cXhsFWnsrvF
-
Dagda RK, Merrill RA, Cribbs JT et al (2008) The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bβ2 antagonizes neuronal survival by promoting mitochondrial fission. J Biol Chem 283:36241-36248
-
(2008)
J Biol Chem
, vol.283
, pp. 36241-36248
-
-
Dagda, R.K.1
Merrill, R.A.2
Cribbs, J.T.3
-
16
-
-
0043092070
-
A developmentally regulated, neuron-specific splice variant of the variable subunit Bβ targets protein phosphatase 2A to mitochondria and modulates apoptosis
-
12716901 10.1074/jbc.M302832200 1:CAS:528:DC%2BD3sXltVSlsb8%3D
-
Dagda RK, Zaucha JA, Wadzinski BE, Strack S (2003) A developmentally regulated, neuron-specific splice variant of the variable subunit Bβ targets protein phosphatase 2A to mitochondria and modulates apoptosis. J Biol Chem 278:24976-24985
-
(2003)
J Biol Chem
, vol.278
, pp. 24976-24985
-
-
Dagda, R.K.1
Zaucha, J.A.2
Wadzinski, B.E.3
Strack, S.4
-
17
-
-
75449084767
-
Oxidative stress promotes autophagic cell death in human neuroblastoma cells with ectopic transfer of mitochondrial PPP2R2B (Bβ2)
-
20017961 10.1186/1471-2121-10-91
-
Cheng WT, Guo ZX, Lin CA, Lin MY, Tung LC, Fang K (2009) Oxidative stress promotes autophagic cell death in human neuroblastoma cells with ectopic transfer of mitochondrial PPP2R2B (Bβ2). BMC Cell Biol 10:91
-
(2009)
BMC Cell Biol
, vol.10
, pp. 91
-
-
Cheng, W.T.1
Guo, Z.X.2
Lin, C.A.3
Lin, M.Y.4
Tung, L.C.5
Fang, K.6
-
18
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
11060023 10.1093/emboj/19.21.5720 1:CAS:528:DC%2BD3cXovFaiurk%3D
-
Kabeya Y, Mizushima N, Ueno T et al (2000) LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 19:5720-5728
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
-
19
-
-
33745866310
-
Autophagic stress in neuronal injury and disease
-
16772866 10.1097/01.jnen.0000229233.75253.be
-
Chu CT (2006) Autophagic stress in neuronal injury and disease. J Neuropathol Exp Neurol 65:423-432
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 423-432
-
-
Chu, C.T.1
-
20
-
-
0005677775
-
3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes
-
6952238 10.1073/pnas.79.6.1889 1:CAS:528:DyaL38Xhslykurc%3D
-
Seglen PO, Gordon PB (1982) 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc Natl Acad Sci USA 79:1889-1892
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 1889-1892
-
-
Seglen, P.O.1
Gordon, P.B.2
-
21
-
-
0035863399
-
A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles
-
11212227 1:CAS:528:DC%2BD3MXht1Gmsr4%3D
-
Paglin S, Hollister T, Delohery T et al (2001) A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Cancer Res 61:439-444
-
(2001)
Cancer Res
, vol.61
, pp. 439-444
-
-
Paglin, S.1
Hollister, T.2
Delohery, T.3
-
22
-
-
0033788787
-
Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations
-
11032905 10.1046/j.1471-4159.2000.0752155.x 1:CAS:528: DC%2BD3cXns1eju7c%3D
-
Goedert M, Satumtira S, Jakes R et al (2000) Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations. J Neurochem 75:2155-2162
-
(2000)
J Neurochem
, vol.75
, pp. 2155-2162
-
-
Goedert, M.1
Satumtira, S.2
Jakes, R.3
-
23
-
-
33745088678
-
Molecular pathogenesis of spinocerebellar ataxias
-
16613893 10.1093/brain/awl081
-
Duenas AM, Goold R, Giunti P (2006) Molecular pathogenesis of spinocerebellar ataxias. Brain 129:1357-1370
-
(2006)
Brain
, vol.129
, pp. 1357-1370
-
-
Duenas, A.M.1
Goold, R.2
Giunti, P.3
-
24
-
-
0034757817
-
The SCA12 mutation as a rare cause of spinocerebellar ataxia
-
11708992 10.1001/archneur.58.11.1833 1:STN:280:DC%2BD3MnosFymug%3D%3D
-
Cholfin JA, Sobrido MJ, Perlman S, Pulst SM, Geschwind DH (2001) The SCA12 mutation as a rare cause of spinocerebellar ataxia. Arch Neurol 58:1833-1835
-
(2001)
Arch Neurol
, vol.58
, pp. 1833-1835
-
-
Cholfin, J.A.1
Sobrido, M.J.2
Perlman, S.3
Pulst, S.M.4
Geschwind, D.H.5
-
25
-
-
50249168137
-
Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: Implications for Parkinson's disease
-
18594198 1:CAS:528:DC%2BD1cXhtVynt7nM
-
Dagda RK, Zhu J, Kulich SM, Chu CT (2008) Mitochondrially localized ERK2 regulates mitophagy and autophagic cell stress: implications for Parkinson's disease. Autophagy 4:770-782
-
(2008)
Autophagy
, vol.4
, pp. 770-782
-
-
Dagda, R.K.1
Zhu, J.2
Kulich, S.M.3
Chu, C.T.4
-
26
-
-
27644466759
-
Autophagy and signaling: Their role in cell survival and cell death
-
16247498 10.1038/sj.cdd.4401751 1:CAS:528:DC%2BD2MXhtFCjt7%2FI
-
Codogno P, Meijer AJ (2005) Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 12(Suppl 2):1509-1518
-
(2005)
Cell Death Differ
, vol.12
, Issue.SUPPL. 2
, pp. 1509-1518
-
-
Codogno, P.1
Meijer, A.J.2
-
27
-
-
41549114279
-
The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease
-
10.1093/brain/awm318
-
Pan T, Kondo S, Le W, Jankovic J (2008) The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease. Brain 13:1969-1978
-
(2008)
Brain
, vol.13
, pp. 1969-1978
-
-
Pan, T.1
Kondo, S.2
Le, W.3
Jankovic, J.4
-
28
-
-
35448938087
-
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration
-
17726112 10.1073/pnas.0701311104 1:CAS:528:DC%2BD2sXhtVGnt7bK
-
Komatsu M, Wang QJ, Holstein GR et al (2007) Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration. Proc Natl Acad Sci USA 104:14489-14494
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14489-14494
-
-
Komatsu, M.1
Wang, Q.J.2
Holstein, G.R.3
-
29
-
-
1842767362
-
3-Methyladenine inhibits autophagy in tobacco culture cells under sucrose starvation conditions
-
15047874 10.1093/pcp/pch031 1:CAS:528:DC%2BD2cXivVChtL4%3D
-
Takatsuka C, Inoue Y, Matsuoka K, Moriyasu Y (2004) 3-Methyladenine inhibits autophagy in tobacco culture cells under sucrose starvation conditions. Plant Cell Physiol 45:265-274
-
(2004)
Plant Cell Physiol
, vol.45
, pp. 265-274
-
-
Takatsuka, C.1
Inoue, Y.2
Matsuoka, K.3
Moriyasu, Y.4
-
30
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
11099404 10.1126/science.290.5497.1717 1:CAS:528:DC%2BD3cXovVOitbw%3D
-
Klionsky DJ, Emr SD (2000) Autophagy as a regulated pathway of cellular degradation. Science 290:1717-1721
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
31
-
-
84861311455
-
Membrane recruitment of autophagy proteins in selective autophagy
-
22236100 10.1111/j.1872-034X.2011.00955.x 1:CAS:528:DC%2BC38Xpt12jtro%3D
-
Morita E, Yoshimori T (2012) Membrane recruitment of autophagy proteins in selective autophagy. Hepatol Res 42:435-441
-
(2012)
Hepatol Res
, vol.42
, pp. 435-441
-
-
Morita, E.1
Yoshimori, T.2
-
32
-
-
84866679306
-
The unique GGA clathrin adaptor of drosophila melanogaster is not essential
-
23028818 10.1371/journal.pone.0045163 1:CAS:528:DC%2BC38XhsVaksbfK
-
Luan S, Ilvarsonn AM, Eissenberg JC (2012) The unique GGA clathrin adaptor of drosophila melanogaster is not essential. PLoS One 7:e45163
-
(2012)
PLoS One
, vol.7
, pp. 45163
-
-
Luan, S.1
Ilvarsonn, A.M.2
Eissenberg, J.C.3
-
33
-
-
0011913143
-
Bafilomycins: A class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells
-
2973058 10.1073/pnas.85.21.7972 1:CAS:528:DyaL1MXjsF2rsA%3D%3D
-
Bowman EJ, Siebers A, Altendorf K (1988) Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells. Proc Natl Acad Sci USA 85:7972-7976
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 7972-7976
-
-
Bowman, E.J.1
Siebers, A.2
Altendorf, K.3
-
34
-
-
84879607395
-
Stress-induced self-cannibalism: On the regulation of autophagy by endoplasmic reticulum stress
-
10.1007/s00018-012-1173-4 23052213
-
Deegan S, Saveljeva S, Gorman AM, Samali A (2012) Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress. Cell Mol Life Sci. doi: 10.1007/s00018-012-1173-4
-
(2012)
Cell Mol Life Sci
-
-
Deegan, S.1
Saveljeva, S.2
Gorman, A.M.3
Samali, A.4
-
35
-
-
80155137546
-
PKA/AKAP1 and PP2A/Bβ2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics
-
22049414 10.1523/JNEUROSCI.3159-11.2011 1:CAS:528:DC%2BC3MXhsVKmsL7E
-
Dickey AS, Strack S (2011) PKA/AKAP1 and PP2A/Bβ2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics. J Neurosci 31:15716-15726
-
(2011)
J Neurosci
, vol.31
, pp. 15716-15726
-
-
Dickey, A.S.1
Strack, S.2
-
36
-
-
47249157360
-
Protein kinase C theta is required for autophagy in response to stress in the endoplasmic reticulum
-
18356160 10.1074/jbc.M710209200 1:CAS:528:DC%2BD1cXmtlynu7k%3D
-
Sakaki K, Wu J, Kaufman RJ (2008) Protein kinase C theta is required for autophagy in response to stress in the endoplasmic reticulum. J Biol Chem 283:15370-15380
-
(2008)
J Biol Chem
, vol.283
, pp. 15370-15380
-
-
Sakaki, K.1
Wu, J.2
Kaufman, R.J.3
-
37
-
-
79958266013
-
Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells
-
21364676 10.1038/cddis.2010.50 1:STN:280:DC%2BC3M3jtVOisQ%3D%3D
-
Bennett HL, Fleming JT, O'Prey J, Ryan KM, Leung HY (2010) Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells. Cell Death Dis 1:e72
-
(2010)
Cell Death Dis
, vol.1
, pp. 72
-
-
Bennett, H.L.1
Fleming, J.T.2
O'Prey, J.3
Ryan, K.M.4
Leung, H.Y.5
-
38
-
-
0034009389
-
Protein phosphatase 2A: A panoply of enzymes
-
10712915 10.1016/S0955-0674(99)00074-5 1:CAS:528:DC%2BD3cXitVantLg%3D
-
Virshup DM (2000) Protein phosphatase 2A: a panoply of enzymes. Curr Opin Cell Biol 12:180-185
-
(2000)
Curr Opin Cell Biol
, vol.12
, pp. 180-185
-
-
Virshup, D.M.1
-
39
-
-
84865155363
-
Inhibitory effect of mTOR activator MHY1485 on autophagy: Suppression of lysosomal fusion
-
22927967 10.1371/journal.pone.0043418 1:CAS:528:DC%2BC38Xht1Gqsb7J
-
Choi YJ, Park YJ, Park JY et al (2012) Inhibitory effect of mTOR activator MHY1485 on autophagy: suppression of lysosomal fusion. PLoS ONE 7:e43418
-
(2012)
PLoS ONE
, vol.7
, pp. 43418
-
-
Choi, Y.J.1
Park, Y.J.2
Park, J.Y.3
-
40
-
-
49949105827
-
The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells
-
18551133 10.1038/cdd.2008.81 1:CAS:528:DC%2BD1cXpvFKnsLw%3D
-
Li J, Ni M, Lee B, Barron E, Hinton DR, Lee AS (2008) The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells. Cell Death Differ 15:1460-1471
-
(2008)
Cell Death Differ
, vol.15
, pp. 1460-1471
-
-
Li, J.1
Ni, M.2
Lee, B.3
Barron, E.4
Hinton, D.R.5
Lee, A.S.6
|