P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in Human colon Cancer cells

Free Radical Biology and Medicine

Volumn 53, Issue 3, 2012, Pages 532-543

  Zhan, Yao ^a   Gong, Ke ^a   Chen, Chao ^a   Wang, Haiqing ^a   Li, Wenhua ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Apoptosis; Autophagy; Free radicals; MS 275; p38; Reactive oxygen species

Indexed keywords

ENTINOSTAT; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CELL DEATH; CELL STRAIN HCT116; COLON CANCER; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHORT COURSE THERAPY; SIGNAL TRANSDUCTION;

ACETYLCYSTEINE; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; BENZAMIDES; CELL SURVIVAL; COLORECTAL NEOPLASMS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FREE RADICAL SCAVENGERS; HCT116 CELLS; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MICE, NUDE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PYRIDINES; REACTIVE OXYGEN SPECIES; TUMOR BURDEN; UBIQUITIN-ACTIVATING ENZYMES; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84863499969     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.05.018     Document Type: Article

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