Inhibition of autophagy strengthens celastrol-induced apoptosis in human pancreatic cancer in vitro and in vivo models

Current Molecular Medicine

Volumn 14, Issue 4, 2014, Pages 555-563

  Zhao, X ^a   Gao, S ^a   Ren, H ^a   Huang, H ^b   Ji, W ^a   Hao, J ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b TIANJIN UNIVERSITY   (China)

Author keywords

3 methyladenine; Apoptosis; Autophagy; Celastrol; Pancreatic cancer; PTEN

Indexed keywords

CELASTROL; 3-METHYLADENINE; ADENINE; TRIPTERINE; TRITERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; MALE; MOUSE; MTT ASSAY; NICK END LABELING; NONHUMAN; PANCREAS CANCER; TUMOR XENOGRAFT; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; CELL PROLIFERATION; CELL SURVIVAL; DISEASE MODEL; DRUG EFFECTS; DRUG SCREENING; METABOLISM; PANCREAS TUMOR; PATHOLOGY; TUMOR CELL LINE; TUMOR VOLUME;

ADENINE; ANIMALS; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MALE; MICE; PANCREATIC NEOPLASMS; TRITERPENES; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84904043345     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/1566524014666140414211223     Document Type: Article

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