-
2
-
-
77950826827
-
Multiple myeloma: A paradigm for translation of the cancer stem cell hypothesis
-
1:CAS:528:DC%2BC3cXkvFKgt7o%3D
-
Agarwal, J.R., and W. Matsui. 2010. Multiple myeloma: A paradigm for translation of the cancer stem cell hypothesis. Anticancer Agents in Medical Chemistry 10: 116-120.
-
(2010)
Anticancer Agents in Medical Chemistry
, vol.10
, pp. 116-120
-
-
Agarwal, J.R.1
Matsui, W.2
-
4
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
1:CAS:528:DC%2BD28Xht1OntbzP 17051156
-
Bao, S., Q. Wu, R.E. Mclendon, Y. Hao, Q. Shi, A.B. Hjelmeland, M.W. Dewhirst, D.D. Bigner, and J.N. Rich. 2006. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444: 756-760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
5
-
-
35348837163
-
Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma
-
2610257 1:CAS:528:DC%2BD2sXht1CltL%2FL 17628016
-
Bar, E.E., A. Chaudhry, A. Lin, X. Fan, K. Schreck, W. Matsui, S. Piccirillo, A.L. Vescovi, F. Dimeco, A. Olivi, and C.G. Eberhart. 2007. Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma. Stem Cells 25: 2524-2533.
-
(2007)
Stem Cells
, vol.25
, pp. 2524-2533
-
-
Bar, E.E.1
Chaudhry, A.2
Lin, A.3
Fan, X.4
Schreck, K.5
Matsui, W.6
Piccirillo, S.7
Vescovi, A.L.8
Dimeco, F.9
Olivi, A.10
Eberhart, C.G.11
-
6
-
-
84859611140
-
Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy
-
3321626 1:CAS:528:DC%2BC38Xlt1WktLs%3D 22117197
-
Bartucci, M., S. Svensson, P. Romania, R. Dattilo, M. Patrizii, M. Signore, S. Navarra, F. Lotti, M. Biffoni, E. Pilozzi, E. Duranti, S. Martinelli, C. Rinaldo, A. Zeuner, M. Maugeri-Sacca, A. Eramo, and R. De Maria. 2012. Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy. Cell Death and Differentiation 19: 768-778.
-
(2012)
Cell Death and Differentiation
, vol.19
, pp. 768-778
-
-
Bartucci, M.1
Svensson, S.2
Romania, P.3
Dattilo, R.4
Patrizii, M.5
Signore, M.6
Navarra, S.7
Lotti, F.8
Biffoni, M.9
Pilozzi, E.10
Duranti, E.11
Martinelli, S.12
Rinaldo, C.13
Zeuner, A.14
Maugeri-Sacca, M.15
Eramo, A.16
De Maria, R.17
-
7
-
-
78650979504
-
DNA-damage response in tissue-specific and cancer stem cells
-
1:CAS:528:DC%2BC3MXjvF2nuw%3D%3D 21211780
-
Blanpain, C., M. Mohrin, P.A. Sotiropoulou, and E. Passegue. 2011. DNA-damage response in tissue-specific and cancer stem cells. Cell Stem Cell 8: 16-29.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 16-29
-
-
Blanpain, C.1
Mohrin, M.2
Sotiropoulou, P.A.3
Passegue, E.4
-
8
-
-
60849117508
-
PTEN/PI3 K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
-
3688060 1:CAS:528:DC%2BD1MXjvVSqsLg%3D 19265662
-
Bleau, A.M., D. Hambardzumyan, T. Ozawa, E.I. Fomchenko, J.T. Huse, C.W. Brennan, and E.C. Holland. 2009. PTEN/PI3 K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell 4: 226-235.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 226-235
-
-
Bleau, A.M.1
Hambardzumyan, D.2
Ozawa, T.3
Fomchenko, E.I.4
Huse, J.T.5
Brennan, C.W.6
Holland, E.C.7
-
9
-
-
84879165722
-
Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma
-
3525024 1:CAS:528:DC%2BC3sXovVKmtg%3D%3D 22821765
-
Blotta, S., J. Jakubikova, T. Calimeri, A.M. Roccaro, N. Amodio, A.K. Azab, U. Foresta, C.S. Mitsiades, M. Rossi, K. Todoerti, S. Molica, F. Morabito, A. Neri, P. Tagliaferri, P. Tassone, K.C. Anderson, and N.C. Munshi. 2012. Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma. Blood 120: 5002-5013.
-
(2012)
Blood
, vol.120
, pp. 5002-5013
-
-
Blotta, S.1
Jakubikova, J.2
Calimeri, T.3
Roccaro, A.M.4
Amodio, N.5
Azab, A.K.6
Foresta, U.7
Mitsiades, C.S.8
Rossi, M.9
Todoerti, K.10
Molica, S.11
Morabito, F.12
Neri, A.13
Tagliaferri, P.14
Tassone, P.15
Anderson, K.C.16
Munshi, N.C.17
-
10
-
-
79551555038
-
Cancer stem cell niche: The place to be
-
1:CAS:528:DC%2BC3MXhsVCis7g%3D 21266356
-
Borovski, T., E.M.F. De Sousa, L. Vermeulen, and J.P. Medema. 2011. Cancer stem cell niche: The place to be. Cancer Research 71: 634-639.
-
(2011)
Cancer Research
, vol.71
, pp. 634-639
-
-
Borovski, T.1
De Sousa, E.M.F.2
Vermeulen, L.3
Medema, J.P.4
-
11
-
-
84866559462
-
Hyaluronan-CD44v3 interaction with Oct4-Sox2-Nanog promotes miR-302 expression leading to self-renewal, clonal formation, and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma
-
3463333 1:CAS:528:DC%2BC38XhtlyqsrnE 22847005
-
Bourguignon, L.Y., G. Wong, C. Earle, and L. Chen. 2012. Hyaluronan-CD44v3 interaction with Oct4-Sox2-Nanog promotes miR-302 expression leading to self-renewal, clonal formation, and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma. The Journal of biological chemistry 287: 32800-32824.
-
(2012)
The Journal of Biological Chemistry
, vol.287
, pp. 32800-32824
-
-
Bourguignon, L.Y.1
Wong, G.2
Earle, C.3
Chen, L.4
-
12
-
-
84866358168
-
The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance
-
1:CAS:528:DC%2BC38Xht1GhsLnN 22918414
-
Bouwman, P., and J. Jonkers. 2012. The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance. Nature Reviews Cancer 12: 587-598.
-
(2012)
Nature Reviews Cancer
, vol.12
, pp. 587-598
-
-
Bouwman, P.1
Jonkers, J.2
-
13
-
-
37749017645
-
The CDK inhibitors: Potential targets for therapeutic stem cell manipulations?
-
1:CAS:528:DC%2BD1cXhtlGquw%3D%3D 17989702
-
Boyer, M.J., and T. Cheng. 2008. The CDK inhibitors: Potential targets for therapeutic stem cell manipulations? Gene Therapy 15: 117-125.
-
(2008)
Gene Therapy
, vol.15
, pp. 117-125
-
-
Boyer, M.J.1
Cheng, T.2
-
14
-
-
58249100053
-
CXCR4 antagonists: Targeting the microenvironment in leukemia and other cancers
-
1:CAS:528:DC%2BD1MXkvVarug%3D%3D 18987663
-
Burger, J.A., and A. Peled. 2009. CXCR4 antagonists: Targeting the microenvironment in leukemia and other cancers. Leukemia 23: 43-52.
-
(2009)
Leukemia
, vol.23
, pp. 43-52
-
-
Burger, J.A.1
Peled, A.2
-
15
-
-
84867096319
-
Orthotopic glioblastoma stem-like cell xenograft model in mice to evaluate intra-arterial delivery of bevacizumab: From bedside to bench
-
1:CAS:528:DC%2BC38XhtlOnt77E 22985932
-
Burkhardt, J.K., C.P. Hofstetter, A. Santillan, B.J. Shin, C.P. Foley, D.J. Ballon, Y. Pierre Gobin, and J.A. Boockvar. 2012. Orthotopic glioblastoma stem-like cell xenograft model in mice to evaluate intra-arterial delivery of bevacizumab: From bedside to bench. Journal of Clinical Neuroscience 19: 1568-1572.
-
(2012)
Journal of Clinical Neuroscience
, vol.19
, pp. 1568-1572
-
-
Burkhardt, J.K.1
Hofstetter, C.P.2
Santillan, A.3
Shin, B.J.4
Foley, C.P.5
Ballon, D.J.6
Pierre Gobin, Y.7
Boockvar, J.A.8
-
17
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
1:CAS:528:DC%2BD2sXhtFClsLY%3D 17222791
-
Calabrese, C., H. Poppleton, M. Kocak, T.L. Hogg, C. Fuller, B. Hamner, E.Y. Oh, M.W. Gaber, D. Finklestein, M. Allen, A. Frank, I.T. Bayazitov, S.S. Zakharenko, A. Gajjar, A. Davidoff, and R.J. Gilbertson. 2007. A perivascular niche for brain tumor stem cells. Cancer Cell 11: 69-82.
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
Hogg, T.L.4
Fuller, C.5
Hamner, B.6
Oh, E.Y.7
Gaber, M.W.8
Finklestein, D.9
Allen, M.10
Frank, A.11
Bayazitov, I.T.12
Zakharenko, S.S.13
Gajjar, A.14
Davidoff, A.15
Gilbertson, R.J.16
-
18
-
-
78149306403
-
Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics
-
2970576 1:CAS:528:DC%2BC3cXhsVSlt7vJ 20935265
-
Calcagno, A.M., C.D. Salcido, J.P. Gillet, C.P. Wu, J.M. Fostel, M.D. Mumau, M.M. Gottesman, L. Varticovski, and S.V. Ambudkar. 2010. Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics. Journal of the National Cancer Institute 102: 1637-1652.
-
(2010)
Journal of the National Cancer Institute
, vol.102
, pp. 1637-1652
-
-
Calcagno, A.M.1
Salcido, C.D.2
Gillet, J.P.3
Wu, C.P.4
Fostel, J.M.5
Mumau, M.D.6
Gottesman, M.M.7
Varticovski, L.8
Ambudkar, S.V.9
-
19
-
-
84879410940
-
C-Kit mediates chemoresistance and tumor-initiating capacity of ovarian cancer cells through activation of Wnt/beta-catenin-ATP-binding cassette G2 signaling
-
1:CAS:528:DC%2BC38XhtVeht7rP 22797058
-
Chau, W.K., C.K. Ip, A.S. Mak, H.C. Lai, and A.S. Wong. 2013. c-Kit mediates chemoresistance and tumor-initiating capacity of ovarian cancer cells through activation of Wnt/beta-catenin-ATP-binding cassette G2 signaling. Oncogene 32: 2767-2781.
-
(2013)
Oncogene
, vol.32
, pp. 2767-2781
-
-
Chau, W.K.1
Ip, C.K.2
Mak, A.S.3
Lai, H.C.4
Wong, A.S.5
-
20
-
-
77952973860
-
CD95 promotes tumour growth
-
2879093 1:CAS:528:DC%2BC3cXmsF2it7w%3D 20505730
-
Chen, L., S.M. Park, A.V. Tumanov, A. Hau, K. Sawada, C. Feig, J.R. Turner, Y.X. Fu, I.L. Romero, E. Lengyel, and M.E. Peter. 2010. CD95 promotes tumour growth. Nature 465: 492-496.
-
(2010)
Nature
, vol.465
, pp. 492-496
-
-
Chen, L.1
Park, S.M.2
Tumanov, A.V.3
Hau, A.4
Sawada, K.5
Feig, C.6
Turner, J.R.7
Fu, Y.X.8
Romero, I.L.9
Lengyel, E.10
Peter, M.E.11
-
21
-
-
47749141560
-
ATR: An essential regulator of genome integrity
-
2663384 1:CAS:528:DC%2BD1cXosl2rsb0%3D 18594563
-
Cimprich, K.A., and D. Cortez. 2008. ATR: An essential regulator of genome integrity. Nature Reviews Molecular Cell Biology 9: 616-627.
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, pp. 616-627
-
-
Cimprich, K.A.1
Cortez, D.2
-
22
-
-
42349093952
-
Cancer stem cells: Implications for the progression and treatment of metastatic disease
-
1:CAS:528:DC%2BD1cXms1aqtbs%3D 18182063
-
Croker, A.K., and A.L. Allan. 2008. Cancer stem cells: Implications for the progression and treatment of metastatic disease. Journal of Cellular and Molecular Medicine 12: 374-390.
-
(2008)
Journal of Cellular and Molecular Medicine
, vol.12
, pp. 374-390
-
-
Croker, A.K.1
Allan, A.L.2
-
23
-
-
74549189337
-
New insights into checkpoint kinase 1 in the DNA damage response signaling network
-
2939735 1:CAS:528:DC%2BC3cXktF2qsb8%3D 20068082
-
Dai, Y., and S. Grant. 2010. New insights into checkpoint kinase 1 in the DNA damage response signaling network. Clinical Cancer Research 16: 376-383.
-
(2010)
Clinical Cancer Research
, vol.16
, pp. 376-383
-
-
Dai, Y.1
Grant, S.2
-
24
-
-
34548592412
-
A phase i clinical trial of the notch inhibitor MK-0752 in patients with T-cell acute lymphoblastic leukemia/lymphoma (T-ALL) and other leukemias
-
Deangelo, D., R. Stone, L. Silverman, W. Stock, E. Attar, I. Fearen, A. Dallob, C. Matthews, J. Stone, and S. Freedman. 2006. A phase I clinical trial of the notch inhibitor MK-0752 in patients with T-cell acute lymphoblastic leukemia/lymphoma (T-ALL) and other leukemias. Journal of Clinical Oncology 24: 6585.
-
(2006)
Journal of Clinical Oncology
, vol.24
, pp. 6585
-
-
Deangelo, D.1
Stone, R.2
Silverman, L.3
Stock, W.4
Attar, E.5
Fearen, I.6
Dallob, A.7
Matthews, C.8
Stone, J.9
Freedman, S.10
-
25
-
-
84899559860
-
CD133+ cells contribute to radioresistance via altered regulation of DNA repair genes in human lung cancer cells
-
1:CAS:528:DC%2BC2cXmvV2gtbo%3D 24440048
-
Desai, A., B. Webb, and S.L. Gerson. 2014. CD133+ cells contribute to radioresistance via altered regulation of DNA repair genes in human lung cancer cells. Radiotherapy and Oncology 110: 538-545.
-
(2014)
Radiotherapy and Oncology
, vol.110
, pp. 538-545
-
-
Desai, A.1
Webb, B.2
Gerson, S.L.3
-
26
-
-
58149380742
-
Stem cell concepts renew cancer research
-
1:CAS:528:DC%2BD1cXhsFWmtr3M 19064739
-
Dick, J.E. 2008. Stem cell concepts renew cancer research. Blood 112: 4793-4807.
-
(2008)
Blood
, vol.112
, pp. 4793-4807
-
-
Dick, J.E.1
-
27
-
-
64749093574
-
Association of reactive oxygen species levels and radioresistance in cancer stem cells
-
2778612 1:CAS:528:DC%2BD1MXhsVCrtbc%3D 19194462
-
Diehn, M., R.W. Cho, N.A. Lobo, T. Kalisky, M.J. Dorie, A.N. Kulp, D. Qian, J.S. Lam, L.E. Ailles, M. Wong, B. Joshua, M.J. Kaplan, I. Wapnir, F.M. Dirbas, G. Somlo, C. Garberoglio, B. Paz, J. Shen, S.K. Lau, S.R. Quake, J.M. Brown, I.L. Weissman, and M.F. Clarke. 2009. Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 458: 780-783.
-
(2009)
Nature
, vol.458
, pp. 780-783
-
-
Diehn, M.1
Cho, R.W.2
Lobo, N.A.3
Kalisky, T.4
Dorie, M.J.5
Kulp, A.N.6
Qian, D.7
Lam, J.S.8
Ailles, L.E.9
Wong, M.10
Joshua, B.11
Kaplan, M.J.12
Wapnir, I.13
Dirbas, F.M.14
Somlo, G.15
Garberoglio, C.16
Paz, B.17
Shen, J.18
Lau, S.K.19
Quake, S.R.20
Brown, J.M.21
Weissman, I.L.22
Clarke, M.F.23
more..
-
28
-
-
84866021276
-
Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch- and hedgehog-dependent tumor-initiating cells
-
1:CAS:528:DC%2BC38XhtlCjtb%2FO 22975379
-
Domingo-Domenech, J., S.J. Vidal, V. Rodriguez-Bravo, M. Castillo-Martin, S.A. Quinn, R. Rodriguez-Barrueco, D.M. Bonal, E. Charytonowicz, N. Gladoun, J. De La Iglesia-Vicente, D.P. Petrylak, M.C. Benson, J.M. Silva, and C. Cordon-Cardo. 2012. Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch- and hedgehog-dependent tumor-initiating cells. Cancer Cell 22: 373-388.
-
(2012)
Cancer Cell
, vol.22
, pp. 373-388
-
-
Domingo-Domenech, J.1
Vidal, S.J.2
Rodriguez-Bravo, V.3
Castillo-Martin, M.4
Quinn, S.A.5
Rodriguez-Barrueco, R.6
Bonal, D.M.7
Charytonowicz, E.8
Gladoun, N.9
De La Iglesia-Vicente, J.10
Petrylak, D.P.11
Benson, M.C.12
Silva, J.M.13
Cordon-Cardo, C.14
-
29
-
-
33144481343
-
The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer
-
1:CAS:528:DC%2BD28XotlGhsQ%3D%3D 16441226
-
Dutton, A., L.S. Young, and P.G. Murray. 2006. The role of cellular FLICE inhibitory protein (c-FLIP) in the pathogenesis and treatment of cancer. Expert Opinion on Therapeutic Targets 10: 27-35.
-
(2006)
Expert Opinion on Therapeutic Targets
, vol.10
, pp. 27-35
-
-
Dutton, A.1
Young, L.S.2
Murray, P.G.3
-
30
-
-
4344587136
-
A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]
-
1:CAS:528:DC%2BD2cXnsVent70%3D
-
Emami, K.H., C. Nguyen, H. Ma, D.H. Kim, K.W. Jeong, M. Eguchi, R.T. Moon, J.L. Teo, H.Y. Kim, S.H. Moon, J.R. Ha, and M. Kahn. 2004. A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]. Proceedings of the National Academy of Sciences of United States of America 101: 12682-12687.
-
(2004)
Proceedings of the National Academy of Sciences of United States of America
, vol.101
, pp. 12682-12687
-
-
Emami, K.H.1
Nguyen, C.2
Ma, H.3
Kim, D.H.4
Jeong, K.W.5
Eguchi, M.6
Moon, R.T.7
Teo, J.L.8
Kim, H.Y.9
Moon, S.H.10
Ha, J.R.11
Kahn, M.12
-
31
-
-
54049115162
-
An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer
-
2605523 1:CAS:528:DC%2BD1cXhtFSms7nE 18790753
-
Feldmann, G., V. Fendrich, K. Mcgovern, D. Bedja, S. Bisht, H. Alvarez, J.B. Koorstra, N. Habbe, C. Karikari, M. Mullendore, K.L. Gabrielson, R. Sharma, W. Matsui, and A. Maitra. 2008. An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer. Molecular Cancer Therapeutics 7: 2725-2735.
-
(2008)
Molecular Cancer Therapeutics
, vol.7
, pp. 2725-2735
-
-
Feldmann, G.1
Fendrich, V.2
McGovern, K.3
Bedja, D.4
Bisht, S.5
Alvarez, H.6
Koorstra, J.B.7
Habbe, N.8
Karikari, C.9
Mullendore, M.10
Gabrielson, K.L.11
Sharma, R.12
Matsui, W.13
Maitra, A.14
-
32
-
-
75149143363
-
ABC transporters in cancer: More than just drug efflux pumps
-
1:CAS:528:DC%2BC3cXlvFGlsQ%3D%3D 20075923
-
Fletcher, J.I., M. Haber, M.J. Henderson, and M.D. Norris. 2010. ABC transporters in cancer: More than just drug efflux pumps. Nature Reviews Cancer 10: 147-156.
-
(2010)
Nature Reviews Cancer
, vol.10
, pp. 147-156
-
-
Fletcher, J.I.1
Haber, M.2
Henderson, M.J.3
Norris, M.D.4
-
33
-
-
33846673934
-
An antagonist of dishevelled protein-protein interaction suppresses beta-catenin-dependent tumor cell growth
-
1:CAS:528:DC%2BD2sXmtVKksw%3D%3D 17234765
-
Fujii, N., L. You, Z. Xu, K. Uematsu, J. Shan, B. He, I. Mikami, L.R. Edmondson, G. Neale, J. Zheng, R.K. Guy, and D.M. Jablons. 2007. An antagonist of dishevelled protein-protein interaction suppresses beta-catenin-dependent tumor cell growth. Cancer Research 67: 573-579.
-
(2007)
Cancer Research
, vol.67
, pp. 573-579
-
-
Fujii, N.1
You, L.2
Xu, Z.3
Uematsu, K.4
Shan, J.5
He, B.6
Mikami, I.7
Edmondson, L.R.8
Neale, G.9
Zheng, J.10
Guy, R.K.11
Jablons, D.M.12
-
34
-
-
84882902651
-
Regulation of apoptosis pathways in cancer stem cells
-
1:CAS:528:DC%2BC38Xlt1Klt7o%3D 22429999
-
Fulda, S. 2013. Regulation of apoptosis pathways in cancer stem cells. Cancer Letters 338: 168-173.
-
(2013)
Cancer Letters
, vol.338
, pp. 168-173
-
-
Fulda, S.1
-
36
-
-
0038626211
-
Tumor response to radiotherapy regulated by endothelial cell apoptosis
-
1:CAS:528:DC%2BD3sXjslGqtrk%3D 12750523
-
Garcia-Barros, M., F. Paris, C. Cordon-Cardo, D. Lyden, S. Rafii, A. Haimovitz-Friedman, Z. Fuks, and R. Kolesnick. 2003. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 300: 1155-1159.
-
(2003)
Science
, vol.300
, pp. 1155-1159
-
-
Garcia-Barros, M.1
Paris, F.2
Cordon-Cardo, C.3
Lyden, D.4
Rafii, S.5
Haimovitz-Friedman, A.6
Fuks, Z.7
Kolesnick, R.8
-
37
-
-
57349162223
-
The critical role of SDF-1/CXCR4 axis in cancer and cancer stem cells metastasis
-
1:CAS:528:DC%2BC3cXisVGhs7g%3D 18997494
-
Gelmini, S., M. Mangoni, M. Serio, P. Romagnani, and E. Lazzeri. 2008. The critical role of SDF-1/CXCR4 axis in cancer and cancer stem cells metastasis. Journal of Endocrinological Investigation 31: 809-819.
-
(2008)
Journal of Endocrinological Investigation
, vol.31
, pp. 809-819
-
-
Gelmini, S.1
Mangoni, M.2
Serio, M.3
Romagnani, P.4
Lazzeri, E.5
-
39
-
-
79952633107
-
Polycomb group proteins in the DNA damage response: A link between radiation resistance and "stemness"
-
1:CAS:528:DC%2BC3MXkvFCqs7k%3D 21346409
-
Gieni, R.S., I.H. Ismail, S. Campbell, and M.J. Hendzel. 2011. Polycomb group proteins in the DNA damage response: A link between radiation resistance and "stemness". Cell Cycle 10: 883-894.
-
(2011)
Cell Cycle
, vol.10
, pp. 883-894
-
-
Gieni, R.S.1
Ismail, I.H.2
Campbell, S.3
Hendzel, M.J.4
-
40
-
-
77956294442
-
Gamma-secretase inhibitors enhance temozolomide treatment of human gliomas by inhibiting neurosphere repopulation and xenograft recurrence
-
2932884 1:CAS:528:DC%2BC3cXhtV2rsLfE 20736377
-
Gilbert, C.A., M.C. Daou, R.P. Moser, and A.H. Ross. 2010. Gamma-secretase inhibitors enhance temozolomide treatment of human gliomas by inhibiting neurosphere repopulation and xenograft recurrence. Cancer Research 70: 6870-6879.
-
(2010)
Cancer Research
, vol.70
, pp. 6870-6879
-
-
Gilbert, C.A.1
Daou, M.C.2
Moser, R.P.3
Ross, A.H.4
-
41
-
-
77958501473
-
DNA damage-mediated induction of a chemoresistant niche
-
2972353 1:CAS:528:DC%2BC3cXhtlKhs73P 21029859
-
Gilbert, L.A., and M.T. Hemann. 2010. DNA damage-mediated induction of a chemoresistant niche. Cell 143: 355-366.
-
(2010)
Cell
, vol.143
, pp. 355-366
-
-
Gilbert, L.A.1
Hemann, M.T.2
-
42
-
-
79956086415
-
BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair
-
3133356 1:CAS:528:DC%2BC3MXotVyrsr8%3D 21383063
-
Ginjala, V., K. Nacerddine, A. Kulkarni, J. Oza, S.J. Hill, M. Yao, E. Citterio, M. Van Lohuizen, and S. Ganesan. 2011. BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair. Molecular and Cellular Biology 31: 1972-1982.
-
(2011)
Molecular and Cellular Biology
, vol.31
, pp. 1972-1982
-
-
Ginjala, V.1
Nacerddine, K.2
Kulkarni, A.3
Oza, J.4
Hill, S.J.5
Yao, M.6
Citterio, E.7
Van Lohuizen, M.8
Ganesan, S.9
-
43
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
1:CAS:528:DC%2BC3MXjsFeqtrk%3D 21376230
-
Hanahan, D., and R.A. Weinberg. 2011. Hallmarks of cancer: The next generation. Cell 144: 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
44
-
-
77956388547
-
CD13 is a therapeutic target in human liver cancer stem cells
-
2929722 1:CAS:528:DC%2BC3cXhtFertbvI 20697159
-
Haraguchi, N., H. Ishii, K. Mimori, F. Tanaka, M. Ohkuma, H.M. Kim, H. Akita, D. Takiuchi, H. Hatano, H. Nagano, G.F. Barnard, Y. Doki, and M. Mori. 2010. CD13 is a therapeutic target in human liver cancer stem cells. Journal of Clinical Investigation 120: 3326-3339.
-
(2010)
Journal of Clinical Investigation
, vol.120
, pp. 3326-3339
-
-
Haraguchi, N.1
Ishii, H.2
Mimori, K.3
Tanaka, F.4
Ohkuma, M.5
Kim, H.M.6
Akita, H.7
Takiuchi, D.8
Hatano, H.9
Nagano, H.10
Barnard, G.F.11
Doki, Y.12
Mori, M.13
-
45
-
-
76549084826
-
Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor
-
3442245 1:CAS:528:DC%2BC3cXltlajsg%3D%3D 20068161
-
Harrison, H., G. Farnie, S.J. Howell, R.E. Rock, S. Stylianou, K.R. Brennan, N.J. Bundred, and R.B. Clarke. 2010. Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor. Cancer Research 70: 709-718.
-
(2010)
Cancer Research
, vol.70
, pp. 709-718
-
-
Harrison, H.1
Farnie, G.2
Howell, S.J.3
Rock, R.E.4
Stylianou, S.5
Brennan, K.R.6
Bundred, N.J.7
Clarke, R.B.8
-
46
-
-
67849124654
-
DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency
-
1:CAS:528:DC%2BD1MXhsVCiu77P 19664991
-
Hoey, T., W.C. Yen, F. Axelrod, J. Basi, L. Donigian, S. Dylla, M. Fitch-Bruhns, S. Lazetic, I.K. Park, A. Sato, S. Satyal, X. Wang, M.F. Clarke, J. Lewicki, and A. Gurney. 2009. DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency. Cell Stem Cell 5: 168-177.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 168-177
-
-
Hoey, T.1
Yen, W.C.2
Axelrod, F.3
Basi, J.4
Donigian, L.5
Dylla, S.6
Fitch-Bruhns, M.7
Lazetic, S.8
Park, I.K.9
Sato, A.10
Satyal, S.11
Wang, X.12
Clarke, M.F.13
Lewicki, J.14
Gurney, A.15
-
47
-
-
84884535896
-
Cancer drug resistance: An evolving paradigm
-
1:CAS:528:DC%2BC3sXhsVyqurnE 24060863
-
Holohan, C., S. Van Schaeybroeck, D.B. Longley, and P.G. Johnston. 2013. Cancer drug resistance: An evolving paradigm. Nature Reviews Cancer 13: 714-726.
-
(2013)
Nature Reviews Cancer
, vol.13
, pp. 714-726
-
-
Holohan, C.1
Van Schaeybroeck, S.2
Longley, D.B.3
Johnston, P.G.4
-
48
-
-
44349103099
-
A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell
-
2396414 1:CAS:528:DC%2BD1cXmtleqs7s%3D 18385154
-
Hong, Z., J. Jiang, L. Lan, S. Nakajima, S. Kanno, H. Koseki, and A. Yasui. 2008. A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell. Nucleic Acids Research 36: 2939-2947.
-
(2008)
Nucleic Acids Research
, vol.36
, pp. 2939-2947
-
-
Hong, Z.1
Jiang, J.2
Lan, L.3
Nakajima, S.4
Kanno, S.5
Koseki, H.6
Yasui, A.7
-
49
-
-
79952528125
-
CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth
-
1:CAS:528:DC%2BC3MXjtFKisrY%3D 21397861
-
Ishimoto, T., O. Nagano, T. Yae, M. Tamada, T. Motohara, H. Oshima, M. Oshima, T. Ikeda, R. Asaba, H. Yagi, T. Masuko, T. Shimizu, T. Ishikawa, K. Kai, E. Takahashi, Y. Imamura, Y. Baba, M. Ohmura, M. Suematsu, H. Baba, and H. Saya. 2011. CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth. Cancer Cell 19: 387-400.
-
(2011)
Cancer Cell
, vol.19
, pp. 387-400
-
-
Ishimoto, T.1
Nagano, O.2
Yae, T.3
Tamada, M.4
Motohara, T.5
Oshima, H.6
Oshima, M.7
Ikeda, T.8
Asaba, R.9
Yagi, H.10
Masuko, T.11
Shimizu, T.12
Ishikawa, T.13
Kai, K.14
Takahashi, E.15
Imamura, Y.16
Baba, Y.17
Ohmura, M.18
Suematsu, M.19
Baba, H.20
Saya, H.21
more..
-
50
-
-
77956407620
-
Hedgehog pathway activation in chronic myeloid leukemia
-
1:CAS:528:DC%2BC3MXlsVahtQ%3D%3D 20928937
-
Jagani, Z., M. Dorsch, and M. Warmuth. 2010. Hedgehog pathway activation in chronic myeloid leukemia. Cell Cycle 9: 3449-3456.
-
(2010)
Cell Cycle
, vol.9
, pp. 3449-3456
-
-
Jagani, Z.1
Dorsch, M.2
Warmuth, M.3
-
51
-
-
34247555482
-
Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies
-
1:CAS:528:DC%2BD2sXksFeltL4%3D 17330101
-
Jiang, X., Y. Zhao, C. Smith, M. Gasparetto, A. Turhan, A. Eaves, and C. Eaves. 2007. Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies. Leukemia 21: 926-935.
-
(2007)
Leukemia
, vol.21
, pp. 926-935
-
-
Jiang, X.1
Zhao, Y.2
Smith, C.3
Gasparetto, M.4
Turhan, A.5
Eaves, A.6
Eaves, C.7
-
52
-
-
81855217368
-
Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy
-
3254167 1:CAS:528:DC%2BC3MXhsFSksL%2FJ 21983179
-
Kendziorra, E., K. Ahlborn, M. Spitzner, M. Rave-Frank, G. Emons, J. Gaedcke, F. Kramer, H.A. Wolff, H. Becker, T. Beissbarth, R. Ebner, B.M. Ghadimi, T. Pukrop, T. Ried, and M. Grade. 2011. Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy. Carcinogenesis 32: 1824-1831.
-
(2011)
Carcinogenesis
, vol.32
, pp. 1824-1831
-
-
Kendziorra, E.1
Ahlborn, K.2
Spitzner, M.3
Rave-Frank, M.4
Emons, G.5
Gaedcke, J.6
Kramer, F.7
Wolff, H.A.8
Becker, H.9
Beissbarth, T.10
Ebner, R.11
Ghadimi, B.M.12
Pukrop, T.13
Ried, T.14
Grade, M.15
-
53
-
-
84864987692
-
Increased CD13 expression reduces reactive oxygen species, promoting survival of liver cancer stem cells via an epithelial-mesenchymal transition-like phenomenon
-
21879266
-
Kim, H.M., N. Haraguchi, H. Ishii, M. Ohkuma, M. Okano, K. Mimori, H. Eguchi, H. Yamamoto, H. Nagano, M. Sekimoto, Y. Doki, and M. Mori. 2012. Increased CD13 expression reduces reactive oxygen species, promoting survival of liver cancer stem cells via an epithelial-mesenchymal transition-like phenomenon. Annals of Surgical Oncology 19(Suppl 3): S539-S548.
-
(2012)
Annals of Surgical Oncology
, vol.19
, pp. 539-S548
-
-
Kim, H.M.1
Haraguchi, N.2
Ishii, H.3
Ohkuma, M.4
Okano, M.5
Mimori, K.6
Eguchi, H.7
Yamamoto, H.8
Nagano, H.9
Sekimoto, M.10
Doki, Y.11
Mori, M.12
-
54
-
-
77949697909
-
Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice
-
2827954 1:CAS:528:DC%2BC3cXjtV2ns74%3D 20179352
-
Kioi, M., H. Vogel, G. Schultz, R.M. Hoffman, G.R. Harsh, and J.M. Brown. 2010. Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice. Journal of Clinical Investigation 120: 694-705.
-
(2010)
Journal of Clinical Investigation
, vol.120
, pp. 694-705
-
-
Kioi, M.1
Vogel, H.2
Schultz, G.3
Hoffman, R.M.4
Harsh, G.R.5
Brown, J.M.6
-
55
-
-
70349735988
-
Therapeutic targeting of microenvironmental interactions in leukemia: Mechanisms and approaches
-
3640296 1:CAS:528:DC%2BD1MXht1OgtbrF 19632887
-
Konopleva, M., Y. Tabe, Z. Zeng, and M. Andreeff. 2009. Therapeutic targeting of microenvironmental interactions in leukemia: Mechanisms and approaches. Drug Resistance Updates 12: 103-113.
-
(2009)
Drug Resistance Updates
, vol.12
, pp. 103-113
-
-
Konopleva, M.1
Tabe, Y.2
Zeng, Z.3
Andreeff, M.4
-
56
-
-
67649969473
-
Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling
-
2683567 19492080
-
Korkaya, H., A. Paulson, E. Charafe-Jauffret, C. Ginestier, M. Brown, J. Dutcher, S.G. Clouthier, and M.S. Wicha. 2009. Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling. PLoS Biology 7: e1000121.
-
(2009)
PLoS Biology
, vol.7
, pp. 1000121
-
-
Korkaya, H.1
Paulson, A.2
Charafe-Jauffret, E.3
Ginestier, C.4
Brown, M.5
Dutcher, J.6
Clouthier, S.G.7
Wicha, M.S.8
-
57
-
-
77953914498
-
Apoptosis and cancer stem cells: Implications for apoptosis targeted therapy
-
1:CAS:528:DC%2BC3cXnvVygurc%3D 20394737
-
Kruyt, F.A., and J.J. Schuringa. 2010. Apoptosis and cancer stem cells: Implications for apoptosis targeted therapy. Biochemical Pharmacology 80: 423-430.
-
(2010)
Biochemical Pharmacology
, vol.80
, pp. 423-430
-
-
Kruyt, F.A.1
Schuringa, J.J.2
-
58
-
-
84884903739
-
Radiation-induced notch signaling in breast cancer stem cells
-
1:CAS:528:DC%2BC3sXhtlCnur3L
-
Lagadec, C., E. Vlashi, Y. Alhiyari, T.M. Phillips, M. Bochkur Dratver, and F. Pajonk. 2013. Radiation-induced notch signaling in breast cancer stem cells. International Journal of Radiation Oncology Biology Physics 87: 609-618.
-
(2013)
International Journal of Radiation Oncology Biology Physics
, vol.87
, pp. 609-618
-
-
Lagadec, C.1
Vlashi, E.2
Alhiyari, Y.3
Phillips, T.M.4
Bochkur Dratver, M.5
Pajonk, F.6
-
59
-
-
84859036222
-
Radiation-induced reprogramming of breast cancer cells
-
3413333 1:CAS:528:DC%2BC38Xns12nt70%3D 22489015
-
Lagadec, C., E. Vlashi, L. Della Donna, C. Dekmezian, and F. Pajonk. 2012. Radiation-induced reprogramming of breast cancer cells. Stem Cells 30: 833-844.
-
(2012)
Stem Cells
, vol.30
, pp. 833-844
-
-
Lagadec, C.1
Vlashi, E.2
Della Donna, L.3
Dekmezian, C.4
Pajonk, F.5
-
60
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
1:STN:280:DyaK2c7ltVKrsg%3D%3D 7509044
-
Lapidot, T., C. Sirard, J. Vormoor, B. Murdoch, T. Hoang, J. Caceres-Cortes, M. Minden, B. Paterson, M.A. Caligiuri, and J.E. Dick. 1994. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367: 645-648.
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
Caceres-Cortes, J.6
Minden, M.7
Paterson, B.8
Caligiuri, M.A.9
Dick, J.E.10
-
61
-
-
84864087971
-
TNFalpha enhances cancer stem cell-like phenotype via Notch-Hes1 activation in oral squamous cell carcinoma cells
-
3488595 1:CAS:528:DC%2BC38XpvFCqtrg%3D 22728043
-
Lee, S.H., H.S. Hong, Z.X. Liu, R.H. Kim, M.K. Kang, N.H. Park, and K.H. Shin. 2012. TNFalpha enhances cancer stem cell-like phenotype via Notch-Hes1 activation in oral squamous cell carcinoma cells. Biochemical Biophysical Research Communications 424: 58-64.
-
(2012)
Biochemical Biophysical Research Communications
, vol.424
, pp. 58-64
-
-
Lee, S.H.1
Hong, H.S.2
Liu, Z.X.3
Kim, R.H.4
Kang, M.K.5
Park, N.H.6
Shin, K.H.7
-
62
-
-
84905898248
-
Getting TRAIL back on track for cancer therapy
-
4131183 1:CAS:528:DC%2BC2cXhtVKmsbnN 24948009
-
Lemke, J., S. Von Karstedt, J. Zinngrebe, and H. Walczak. 2014. Getting TRAIL back on track for cancer therapy. Cell Death and Differentiation 21: 1350-1364.
-
(2014)
Cell Death and Differentiation
, vol.21
, pp. 1350-1364
-
-
Lemke, J.1
Von Karstedt, S.2
Zinngrebe, J.3
Walczak, H.4
-
63
-
-
0035760302
-
Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: A Southwest Oncology Group study
-
1:CAS:528:DC%2BD3MXovVSgsrc%3D 11719356
-
List, A.F., K.J. Kopecky, C.L. Willman, D.R. Head, D.L. Persons, M.L. Slovak, R. Dorr, C. Karanes, H.E. Hynes, J.H. Doroshow, M. Shurafa, and F.R. Appelbaum. 2001. Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: A Southwest Oncology Group study. Blood 98: 3212-3220.
-
(2001)
Blood
, vol.98
, pp. 3212-3220
-
-
List, A.F.1
Kopecky, K.J.2
Willman, C.L.3
Head, D.R.4
Persons, D.L.5
Slovak, M.L.6
Dorr, R.7
Karanes, C.8
Hynes, H.E.9
Doroshow, J.H.10
Shurafa, M.11
Appelbaum, F.R.12
-
64
-
-
84903446187
-
NOTCH1 signaling promotes chemoresistance via regulating ABCC1 expression in prostate cancer stem cells
-
1:CAS:528:DC%2BC2cXntVCgurY%3D 24782036
-
Liu, C., Z. Li, L. Bi, K. Li, B. Zhou, C. Xu, J. Huang, and K. Xu. 2014. NOTCH1 signaling promotes chemoresistance via regulating ABCC1 expression in prostate cancer stem cells. Molecular and Cellular Biochemistry 393: 265-270.
-
(2014)
Molecular and Cellular Biochemistry
, vol.393
, pp. 265-270
-
-
Liu, C.1
Li, Z.2
Bi, L.3
Li, K.4
Zhou, B.5
Xu, C.6
Huang, J.7
Xu, K.8
-
65
-
-
33845671339
-
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
-
1697823 17140455
-
Liu, G., X. Yuan, Z. Zeng, P. Tunici, H. Ng, I.R. Abdulkadir, L. Lu, D. Irvin, K.L. Black, and J.S. Yu. 2006a. Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Molecular Cancer 5: 67-79.
-
(2006)
Molecular Cancer
, vol.5
, pp. 67-79
-
-
Liu, G.1
Yuan, X.2
Zeng, Z.3
Tunici, P.4
Ng, H.5
Abdulkadir, I.R.6
Lu, L.7
Irvin, D.8
Black, K.L.9
Yu, J.S.10
-
66
-
-
33745728170
-
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
-
1:CAS:528:DC%2BD28XlvVSksrY%3D 16778178
-
Liu, S., G. Dontu, I.D. Mantle, S. Patel, N.S. Ahn, K.W. Jackson, P. Suri, and M.S. Wicha. 2006b. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Research 66: 6063-6071.
-
(2006)
Cancer Research
, vol.66
, pp. 6063-6071
-
-
Liu, S.1
Dontu, G.2
Mantle, I.D.3
Patel, S.4
Ahn, N.S.5
Jackson, K.W.6
Suri, P.7
Wicha, M.S.8
-
67
-
-
55249090050
-
A first-in-human, first-in-class, phase (ph) i study of systemic Hedgehog (Hh) pathway antagonist, GDC-0449, in patients (pts) with advanced solid tumors
-
Lorusso, P., C. Rudin, M. Borad, L. Vernillet, W. Darbonne, H. Mackey, J. Dimartino, F. De Sauvage, J. Low, and D. Von Hoff. 2008. A first-in-human, first-in-class, phase (ph) I study of systemic Hedgehog (Hh) pathway antagonist, GDC-0449, in patients (pts) with advanced solid tumors. Journal of Clinical Oncology 26: 3516.
-
(2008)
Journal of Clinical Oncology
, vol.26
, pp. 3516
-
-
Lorusso, P.1
Rudin, C.2
Borad, M.3
Vernillet, L.4
Darbonne, W.5
Mackey, H.6
Dimartino, J.7
De Sauvage, F.8
Low, J.9
Von Hoff, D.10
-
68
-
-
9244224723
-
Intrinsic tumour suppression
-
1:CAS:528:DC%2BD2cXpvVCjtLg%3D 15549092
-
Lowe, S.W., E. Cepero, and G. Evan. 2004. Intrinsic tumour suppression. Nature 432: 307-315.
-
(2004)
Nature
, vol.432
, pp. 307-315
-
-
Lowe, S.W.1
Cepero, E.2
Evan, G.3
-
69
-
-
84873728505
-
Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1
-
3574187 1:CAS:528:DC%2BC3sXhvFWru7c%3D 23375636
-
Lu, J., X. Ye, F. Fan, L. Xia, R. Bhattacharya, S. Bellister, F. Tozzi, E. Sceusi, Y. Zhou, I. Tachibana, D.M. Maru, D.H. Hawke, J. Rak, S.A. Mani, P. Zweidler-Mckay, and L.M. Ellis. 2013. Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1. Cancer Cell 23: 171-185.
-
(2013)
Cancer Cell
, vol.23
, pp. 171-185
-
-
Lu, J.1
Ye, X.2
Fan, F.3
Xia, L.4
Bhattacharya, R.5
Bellister, S.6
Tozzi, F.7
Sceusi, E.8
Zhou, Y.9
Tachibana, I.10
Maru, D.M.11
Hawke, D.H.12
Rak, J.13
Mani, S.A.14
Zweidler-Mckay, P.15
Ellis, L.M.16
-
70
-
-
66249139555
-
CD44+ cancer cells express higher levels of the anti-apoptotic protein Bcl-2 in breast tumours
-
2935767 19385591
-
Madjd, Z., A.Z. Mehrjerdi, A.M. Sharifi, S. Molanaei, S.Z. Shahzadi, and M. Asadi-Lari. 2009. CD44+ cancer cells express higher levels of the anti-apoptotic protein Bcl-2 in breast tumours. Cancer Immunity 9: 4.
-
(2009)
Cancer Immunity
, vol.9
, pp. 4
-
-
Madjd, Z.1
Mehrjerdi, A.Z.2
Sharifi, A.M.3
Molanaei, S.4
Shahzadi, S.Z.5
Asadi-Lari, M.6
-
71
-
-
84858608410
-
Cancer stem cells: Impact, heterogeneity, and uncertainty
-
1:CAS:528:DC%2BC38Xkt1yltro%3D 22439924
-
Magee, J.A., E. Piskounova, and S.J. Morrison. 2012. Cancer stem cells: Impact, heterogeneity, and uncertainty. Cancer Cell 21: 283-296.
-
(2012)
Cancer Cell
, vol.21
, pp. 283-296
-
-
Magee, J.A.1
Piskounova, E.2
Morrison, S.J.3
-
72
-
-
80052182327
-
Radioresistance of glioma stem cells: Intrinsic characteristic or property of the 'microenvironment-stem cell unit'?
-
1:CAS:528:DC%2BC3MXhtVyqtL%2FN 21659010
-
Mannino, M., and A.J. Chalmers. 2011. Radioresistance of glioma stem cells: Intrinsic characteristic or property of the 'microenvironment-stem cell unit'? Molecular Oncology 5: 374-386.
-
(2011)
Molecular Oncology
, vol.5
, pp. 374-386
-
-
Mannino, M.1
Chalmers, A.J.2
-
73
-
-
0025774243
-
A method for the selective measurement of the radiosensitivity of quiescent cells in solid tumors-combination of immunofluorescence staining to BrdU and micronucleus assay
-
1:CAS:528:DyaK3MXhtl2jsrY%3D 1705716
-
Masunaga, S., K. Ono, and M. Abe. 1991. A method for the selective measurement of the radiosensitivity of quiescent cells in solid tumors-combination of immunofluorescence staining to BrdU and micronucleus assay. Radiation Research 125: 243-247.
-
(1991)
Radiation Research
, vol.125
, pp. 243-247
-
-
Masunaga, S.1
Ono, K.2
Abe, M.3
-
75
-
-
84867919330
-
Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy
-
1:CAS:528:DC%2BC38XhvVShtbzO
-
Mcauliffe, S.M., S.L. Morgan, G.A. Wyant, L.T. Tran, K.W. Muto, Y.S. Chen, K.T. Chin, J.C. Partridge, B.B. Poole, K.H. Cheng, J. Daggett Jr, K. Cullen, E. Kantoff, K. Hasselbatt, J. Berkowitz, M.G. Muto, R.S. Berkowitz, J.C. Aster, U.A. Matulonis, and D.M. Dinulescu. 2012. Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy. Proceedings of the National Academy of Sciences of United States of America 109: E2939-E2948.
-
(2012)
Proceedings of the National Academy of Sciences of United States of America
, vol.109
, pp. 2939-E2948
-
-
McAuliffe, S.M.1
Morgan, S.L.2
Wyant, G.A.3
Tran, L.T.4
Muto, K.W.5
Chen, Y.S.6
Chin, K.T.7
Partridge, J.C.8
Poole, B.B.9
Cheng, K.H.10
Daggett, Jr.J.11
Cullen, K.12
Kantoff, E.13
Hasselbatt, K.14
Berkowitz, J.15
Muto, M.G.16
Berkowitz, R.S.17
Aster, J.C.18
Matulonis, U.A.19
Dinulescu, D.M.20
more..
-
76
-
-
54849404458
-
MMEJ repair of double-strand breaks (director's cut): Deleted sequences and alternative endings
-
1:CAS:528:DC%2BD1cXhtlaqurbO 18809224
-
Mcvey, M., and S.E. Lee. 2008. MMEJ repair of double-strand breaks (director's cut): Deleted sequences and alternative endings. Trends in Genetics 24: 529-538.
-
(2008)
Trends in Genetics
, vol.24
, pp. 529-538
-
-
McVey, M.1
Lee, S.E.2
-
77
-
-
1842532997
-
VX-710 (biricodar) increases drug retention and enhances chemosensitivity in resistant cells overexpressing P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein
-
1:CAS:528:DC%2BD2cXhvFClt7c%3D 15014037
-
Minderman, H., K.L. O'loughlin, L. Pendyala, and M.R. Baer. 2004. VX-710 (biricodar) increases drug retention and enhances chemosensitivity in resistant cells overexpressing P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein. Clinical Cancer Research 10: 1826-1834.
-
(2004)
Clinical Cancer Research
, vol.10
, pp. 1826-1834
-
-
Minderman, H.1
O'Loughlin, K.L.2
Pendyala, L.3
Baer, M.R.4
-
78
-
-
78349252704
-
Quiescent, slow-cycling stem cell populations in cancer: A review of the evidence and discussion of significance
-
2948913 20936110
-
Moore, N., and S. Lyle. 2011. Quiescent, slow-cycling stem cell populations in cancer: A review of the evidence and discussion of significance. Journal of Oncology 2011: 396076.
-
(2011)
Journal of Oncology
, vol.2011
, pp. 396076
-
-
Moore, N.1
Lyle, S.2
-
79
-
-
84878633794
-
Drug review: Safety and efficacy of bevacizumab for glioblastoma and other brain tumors
-
23585688
-
Narita, Y. 2013. Drug review: Safety and efficacy of bevacizumab for glioblastoma and other brain tumors. Japanese Journal of Clinical Oncology 43: 587-595.
-
(2013)
Japanese Journal of Clinical Oncology
, vol.43
, pp. 587-595
-
-
Narita, Y.1
-
80
-
-
8544241727
-
The prognostic significance of expression of the multidrug resistance-associated protein (MRP) in primary breast cancer
-
2227995 1:CAS:528:DyaK2sXlvV2nsLo%3D 9275026
-
Nooter, K., G. Brutel De La Riviere, M.P. Look, K.E. Van Wingerden, S.C. Henzen-Logmans, R.J. Scheper, M.J. Flens, J.G. Klijn, G. Stoter, and J.A. Foekens. 1997. The prognostic significance of expression of the multidrug resistance-associated protein (MRP) in primary breast cancer. British Journal of Cancer 76: 486-493.
-
(1997)
British Journal of Cancer
, vol.76
, pp. 486-493
-
-
Nooter, K.1
Brutel De La Riviere, G.2
Look, M.P.3
Van Wingerden, K.E.4
Henzen-Logmans, S.C.5
Scheper, R.J.6
Flens, M.J.7
Klijn, J.G.8
Stoter, G.9
Foekens, J.A.10
-
82
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
1:CAS:528:DC%2BD2MXktlSiu7w%3D 15882617
-
Orimo, A., P.B. Gupta, D.C. Sgroi, F. Arenzana-Seisdedos, T. Delaunay, R. Naeem, V.J. Carey, A.L. Richardson, and R.A. Weinberg. 2005. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121: 335-348.
-
(2005)
Cell
, vol.121
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
Carey, V.J.7
Richardson, A.L.8
Weinberg, R.A.9
-
83
-
-
67349243616
-
Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance
-
1:CAS:528:DC%2BD1MXlvFGjt7c%3D 19331851
-
Patil, Y., T. Sadhukha, L. Ma, and J. Panyam. 2009. Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance. Journal of Controlled Release 136: 21-29.
-
(2009)
Journal of Controlled Release
, vol.136
, pp. 21-29
-
-
Patil, Y.1
Sadhukha, T.2
Ma, L.3
Panyam, J.4
-
85
-
-
33845904383
-
The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation
-
17179479
-
Phillips, T.M., W.H. Mcbride, and F. Pajonk. 2006. The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation. Journal of the National Cancer Institute 98: 1777-1785.
-
(2006)
Journal of the National Cancer Institute
, vol.98
, pp. 1777-1785
-
-
Phillips, T.M.1
McBride, W.H.2
Pajonk, F.3
-
86
-
-
79953014281
-
Wnt signaling regulates symmetry of division of neural stem cells in the adult brain and in response to injury
-
1:CAS:528:DC%2BC3MXlvFKjsrg%3D 21425415
-
Piccin, D., and C.M. Morshead. 2011. Wnt signaling regulates symmetry of division of neural stem cells in the adult brain and in response to injury. Stem Cells 29: 528-538.
-
(2011)
Stem Cells
, vol.29
, pp. 528-538
-
-
Piccin, D.1
Morshead, C.M.2
-
87
-
-
84893435197
-
Enhanced MGMT expression contributes to temozolomide resistance in glioma stem-like cells
-
3935013 1:CAS:528:DC%2BC2cXhtlKhs7vP 23958055
-
Qiu, Z.K., D. Shen, Y.S. Chen, Q.Y. Yang, C.C. Guo, B.H. Feng, and Z.P. Chen. 2014. Enhanced MGMT expression contributes to temozolomide resistance in glioma stem-like cells. Chinese Journal of Cancer 33: 115-122.
-
(2014)
Chinese Journal of Cancer
, vol.33
, pp. 115-122
-
-
Qiu, Z.K.1
Shen, D.2
Chen, Y.S.3
Yang, Q.Y.4
Guo, C.C.5
Feng, B.H.6
Chen, Z.P.7
-
88
-
-
79955460636
-
Notch signalling in solid tumours: A little bit of everything but not all the time
-
1:CAS:528:DC%2BC3MXks1ags7g%3D 21508972
-
Ranganathan, P., K.L. Weaver, and A.J. Capobianco. 2011. Notch signalling in solid tumours: A little bit of everything but not all the time. Nature Reviews Cancer 11: 338-351.
-
(2011)
Nature Reviews Cancer
, vol.11
, pp. 338-351
-
-
Ranganathan, P.1
Weaver, K.L.2
Capobianco, A.J.3
-
89
-
-
84878785804
-
A drug from poison: How the therapeutic effect of arsenic trioxide on acute promyelocytic leukemia was discovered
-
1:CAS:528:DC%2BC3sXptFequrs%3D 23645104
-
Rao, Y., R. Li, and D. Zhang. 2013. A drug from poison: How the therapeutic effect of arsenic trioxide on acute promyelocytic leukemia was discovered. Science China Life Sciences 56: 495-502.
-
(2013)
Science China Life Sciences
, vol.56
, pp. 495-502
-
-
Rao, Y.1
Li, R.2
Zhang, D.3
-
90
-
-
0033451738
-
TNF-induced signaling in apoptosis
-
1:CAS:528:DC%2BD3cXmtFSitQ%3D%3D 10634209
-
Rath, P.C., and B.B. Aggarwal. 1999. TNF-induced signaling in apoptosis. Journal of Clinical Immunology 19: 350-364.
-
(1999)
Journal of Clinical Immunology
, vol.19
, pp. 350-364
-
-
Rath, P.C.1
Aggarwal, B.B.2
-
91
-
-
58149336788
-
Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
-
2692090 1:CAS:528:DC%2BD1cXhsFajtbfN 19098907
-
Real, P.J., V. Tosello, T. Palomero, M. Castillo, E. Hernando, E. De Stanchina, M.L. Sulis, K. Barnes, C. Sawai, I. Homminga, J. Meijerink, I. Aifantis, G. Basso, C. Cordon-Cardo, W. Ai, and A. Ferrando. 2009. Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia. Nature Medicine 15: 50-58.
-
(2009)
Nature Medicine
, vol.15
, pp. 50-58
-
-
Real, P.J.1
Tosello, V.2
Palomero, T.3
Castillo, M.4
Hernando, E.5
De Stanchina, E.6
Sulis, M.L.7
Barnes, K.8
Sawai, C.9
Homminga, I.10
Meijerink, J.11
Aifantis, I.12
Basso, G.13
Cordon-Cardo, C.14
Ai, W.15
Ferrando, A.16
-
92
-
-
63749131243
-
Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2
-
2699687 1:CAS:528:DC%2BD1MXksVClu7k%3D 19230643
-
Reinhardt, H.C., and M.B. Yaffe. 2009. Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2. Current Opinion in Cell Biology 21: 245-255.
-
(2009)
Current Opinion in Cell Biology
, vol.21
, pp. 245-255
-
-
Reinhardt, H.C.1
Yaffe, M.B.2
-
93
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
1:CAS:528:DC%2BD3MXot1ahs7c%3D 11689955
-
Reya, T., S.J. Morrison, M.F. Clarke, and I.L. Weissman. 2001. Stem cells, cancer, and cancer stem cells. Nature 414: 105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
94
-
-
35148888629
-
Cancer stem cells in radiation resistance
-
1:CAS:528:DC%2BD2sXhtFSntbfP 17908997
-
Rich, J.N. 2007. Cancer stem cells in radiation resistance. Cancer Research 67: 8980-8984.
-
(2007)
Cancer Research
, vol.67
, pp. 8980-8984
-
-
Rich, J.N.1
-
95
-
-
79951825513
-
Ovarian cancer stem cell-like side populations are enriched following chemotherapy and overexpress EZH2
-
3037846 1:CAS:528:DC%2BC3MXhs1ylsLg%3D 21216927
-
Rizzo, S., J.M. Hersey, P. Mellor, W. Dai, A. Santos-Silva, D. Liber, L. Luk, I. Titley, C.P. Carden, G. Box, D.L. Hudson, S.B. Kaye, and R. Brown. 2011. Ovarian cancer stem cell-like side populations are enriched following chemotherapy and overexpress EZH2. Molecular Cancer Therapeutics 10: 325-335.
-
(2011)
Molecular Cancer Therapeutics
, vol.10
, pp. 325-335
-
-
Rizzo, S.1
Hersey, J.M.2
Mellor, P.3
Dai, W.4
Santos-Silva, A.5
Liber, D.6
Luk, L.7
Titley, I.8
Carden, C.P.9
Box, G.10
Hudson, D.L.11
Kaye, S.B.12
Brown, R.13
-
96
-
-
33846453969
-
PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery
-
1:CAS:528:DC%2BD2sXpsVyksg%3D%3D 16924674
-
Rouleau, M., D. Mcdonald, P. Gagne, M.E. Ouellet, A. Droit, J.M. Hunter, S. Dutertre, C. Prigent, M.J. Hendzel, and G.G. Poirier. 2007. PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery. Journal of Cellular Biochemistry 100: 385-401.
-
(2007)
Journal of Cellular Biochemistry
, vol.100
, pp. 385-401
-
-
Rouleau, M.1
McDonald, D.2
Gagne, P.3
Ouellet, M.E.4
Droit, A.5
Hunter, J.M.6
Dutertre, S.7
Prigent, C.8
Hendzel, M.J.9
Poirier, G.G.10
-
97
-
-
0036088471
-
IAP proteins: Blocking the road to death's door
-
1:CAS:528:DC%2BD38XltlartL4%3D 12042762
-
Salvesen, G.S., and C.S. Duckett. 2002. IAP proteins: Blocking the road to death's door. Nature Reviews Molecular Cell Biology 3: 401-410.
-
(2002)
Nature Reviews Molecular Cell Biology
, vol.3
, pp. 401-410
-
-
Salvesen, G.S.1
Duckett, C.S.2
-
98
-
-
70349547152
-
Identification and targeting of cancer stem cells
-
2887758 1:CAS:528:DC%2BD1MXhtlynsL7I 19708024
-
Schatton, T., N.Y. Frank, and M.H. Frank. 2009. Identification and targeting of cancer stem cells. BioEssays 31: 1038-1049.
-
(2009)
BioEssays
, vol.31
, pp. 1038-1049
-
-
Schatton, T.1
Frank, N.Y.2
Frank, M.H.3
-
99
-
-
38349165576
-
Identification of cells initiating human melanomas
-
3660705 1:CAS:528:DC%2BD1cXnt1Gisg%3D%3D 18202660
-
Schatton, T., G.F. Murphy, N.Y. Frank, K. Yamaura, A.M. Waaga-Gasser, M. Gasser, Q. Zhan, S. Jordan, L.M. Duncan, C. Weishaupt, R.C. Fuhlbrigge, T.S. Kupper, M.H. Sayegh, and M.H. Frank. 2008. Identification of cells initiating human melanomas. Nature 451: 345-349.
-
(2008)
Nature
, vol.451
, pp. 345-349
-
-
Schatton, T.1
Murphy, G.F.2
Frank, N.Y.3
Yamaura, K.4
Waaga-Gasser, A.M.5
Gasser, M.6
Zhan, Q.7
Jordan, S.8
Duncan, L.M.9
Weishaupt, C.10
Fuhlbrigge, R.C.11
Kupper, T.S.12
Sayegh, M.H.13
Frank, M.H.14
-
100
-
-
28244496603
-
Identification of a specific inhibitor of the dishevelled PDZ domain
-
1:CAS:528:DC%2BD2MXhtFynur%2FK 16300398
-
Shan, J., D.L. Shi, J. Wang, and J. Zheng. 2005. Identification of a specific inhibitor of the dishevelled PDZ domain. Biochemistry 44: 15495-15503.
-
(2005)
Biochemistry
, vol.44
, pp. 15495-15503
-
-
Shan, J.1
Shi, D.L.2
Wang, J.3
Zheng, J.4
-
101
-
-
84859829553
-
Reactive oxygen species in cancer stem cells
-
1:CAS:528:DC%2BC38Xls1Witbw%3D
-
Shi, X., Y. Zhang, J. Zheng, and J. Pan. 2012. Reactive oxygen species in cancer stem cells. Antioxidants & Redox Signaling 16: 1215-1228.
-
(2012)
Antioxidants & Redox Signaling
, vol.16
, pp. 1215-1228
-
-
Shi, X.1
Zhang, Y.2
Zheng, J.3
Pan, J.4
-
102
-
-
0035253615
-
ATM and ATR: Networking cellular responses to DNA damage
-
1:CAS:528:DC%2BD3MXhtFSntLk%3D
-
Shiloh, Y. 2001. ATM and ATR: Networking cellular responses to DNA damage. Current Opinion in Genetics & Development 11: 71-77.
-
(2001)
Current Opinion in Genetics & Development
, vol.11
, pp. 71-77
-
-
Shiloh, Y.1
-
103
-
-
79952318891
-
Sonic hedgehog pathway is essential for maintenance of cancer stem-like cells in human gastric cancer
-
3048871 1:CAS:528:DC%2BC3MXjtl2mt7Y%3D 21394208
-
Song, Z., W. Yue, B. Wei, N. Wang, T. Li, L. Guan, S. Shi, Q. Zeng, X. Pei, and L. Chen. 2011. Sonic hedgehog pathway is essential for maintenance of cancer stem-like cells in human gastric cancer. PLoS One 6: e17687.
-
(2011)
PLoS One
, vol.6
, pp. 17687
-
-
Song, Z.1
Yue, W.2
Wei, B.3
Wang, N.4
Li, T.5
Guan, L.6
Shi, S.7
Zeng, Q.8
Pei, X.9
Chen, L.10
-
104
-
-
77957735709
-
TNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype
-
2939957 1:CAS:528:DC%2BC3cXhtFGqsL7P 20509143
-
Storci, G., P. Sansone, S. Mari, G. D'uva, S. Tavolari, T. Guarnieri, M. Taffurelli, C. Ceccarelli, D. Santini, P. Chieco, K.B. Marcu, and M. Bonafe. 2010. TNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype. Journal of Cellular Physiology 225: 682-691.
-
(2010)
Journal of Cellular Physiology
, vol.225
, pp. 682-691
-
-
Storci, G.1
Sansone, P.2
Mari, S.3
D'Uva, G.4
Tavolari, S.5
Guarnieri, T.6
Taffurelli, M.7
Ceccarelli, C.8
Santini, D.9
Chieco, P.10
Marcu, K.B.11
Bonafe, M.12
-
106
-
-
56149097601
-
Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins
-
1:CAS:528:DC%2BD1cXhtlegurfN 18663354
-
Tagscherer, K.E., A. Fassl, B. Campos, M. Farhadi, A. Kraemer, B.C. Bock, S. Macher-Goeppinger, B. Radlwimmer, O.D. Wiestler, C. Herold-Mende, and W. Roth. 2008. Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins. Oncogene 27: 6646-6656.
-
(2008)
Oncogene
, vol.27
, pp. 6646-6656
-
-
Tagscherer, K.E.1
Fassl, A.2
Campos, B.3
Farhadi, M.4
Kraemer, A.5
Bock, B.C.6
Macher-Goeppinger, S.7
Radlwimmer, B.8
Wiestler, O.D.9
Herold-Mende, C.10
Roth, W.11
-
107
-
-
0034738979
-
Effects of oncogenic mutations in smoothened and Patched can be reversed by cyclopamine
-
1:CAS:528:DC%2BD3cXmtlOjtrs%3D 10984056
-
Taipale, J., J.K. Chen, M.K. Cooper, B. Wang, R.K. Mann, L. Milenkovic, M.P. Scott, and P.A. Beachy. 2000. Effects of oncogenic mutations in smoothened and Patched can be reversed by cyclopamine. Nature 406: 1005-1009.
-
(2000)
Nature
, vol.406
, pp. 1005-1009
-
-
Taipale, J.1
Chen, J.K.2
Cooper, M.K.3
Wang, B.4
Mann, R.K.5
Milenkovic, L.6
Scott, M.P.7
Beachy, P.A.8
-
108
-
-
79551600015
-
Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
-
1:CAS:528:DC%2BC3MXht1yrt7Y%3D 21151206
-
Takebe, N., P.J. Harris, R.Q. Warren, and S.P. Ivy. 2011. Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nature Reviews Clinical Oncology 8: 97-106.
-
(2011)
Nature Reviews Clinical Oncology
, vol.8
, pp. 97-106
-
-
Takebe, N.1
Harris, P.J.2
Warren, R.Q.3
Ivy, S.P.4
-
109
-
-
84857789336
-
Understanding cancer stem cell heterogeneity and plasticity
-
3292302 1:CAS:528:DC%2BC38Xjt1Wjurw%3D 22357481
-
Tang, D.G. 2012. Understanding cancer stem cell heterogeneity and plasticity. Cell Research 22: 457-472.
-
(2012)
Cell Research
, vol.22
, pp. 457-472
-
-
Tang, D.G.1
-
110
-
-
67650071137
-
Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
-
1:CAS:528:DC%2BD1MXmsFWqsLk%3D 19478820
-
Trachootham, D., J. Alexandre, and P. Huang. 2009. Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach? Nature Reviews Drug Discovery 8: 579-591.
-
(2009)
Nature Reviews Drug Discovery
, vol.8
, pp. 579-591
-
-
Trachootham, D.1
Alexandre, J.2
Huang, P.3
-
111
-
-
84905404344
-
CXCR4 as biomarker for radioresistant cancer stem cells
-
1:CAS:528:DC%2BC2cXht1GnsbbO 24650104
-
Trautmann, F., M. Cojoc, I. Kurth, N. Melin, L.C. Bouchez, A. Dubrovska, and C. Peitzsch. 2014. CXCR4 as biomarker for radioresistant cancer stem cells. International Journal of Radiation Biology 90: 687-699.
-
(2014)
International Journal of Radiation Biology
, vol.90
, pp. 687-699
-
-
Trautmann, F.1
Cojoc, M.2
Kurth, I.3
Melin, N.4
Bouchez, L.C.5
Dubrovska, A.6
Peitzsch, C.7
-
112
-
-
33751104270
-
Multidrug resistance in small cell lung cancer: Expression of P-glycoprotein, multidrug resistance protein 1 and lung resistance protein in chemo-naive patients and in relapsed disease
-
16934363
-
Triller, N., P. Korosec, I. Kern, M. Kosnik, and A. Debeljak. 2006. Multidrug resistance in small cell lung cancer: Expression of P-glycoprotein, multidrug resistance protein 1 and lung resistance protein in chemo-naive patients and in relapsed disease. Lung Cancer 54: 235-240.
-
(2006)
Lung Cancer
, vol.54
, pp. 235-240
-
-
Triller, N.1
Korosec, P.2
Kern, I.3
Kosnik, M.4
Debeljak, A.5
-
113
-
-
83055168538
-
Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target
-
011353
-
Van Houdt, W.J., B.L. Emmink, T.V. Pham, S.R. Piersma, A. Verheem, R.G. Vries, S.A. Fratantoni, A. Pronk, H. Clevers, C.R. Jimenez, and O. Kranenburg. 2011. Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target. Molecular & Cellular Proteomics 10: M111 011353.
-
(2011)
Molecular & Cellular Proteomics
, vol.10
, pp. 111
-
-
Van Houdt, W.J.1
Emmink, B.L.2
Pham, T.V.3
Piersma, S.R.4
Verheem, A.5
Vries, R.G.6
Fratantoni, S.A.7
Pronk, A.8
Clevers, H.9
Jimenez, C.R.10
Kranenburg, O.11
-
114
-
-
85027928015
-
Wnt pathway activity confers chemoresistance to cancer stem-like cells in a neuroblastoma cell line
-
1:CAS:528:DC%2BC38Xhs12murbF 22886526
-
Vangipuram, S.D., S.A. Buck, and W.D. Lyman. 2012. Wnt pathway activity confers chemoresistance to cancer stem-like cells in a neuroblastoma cell line. Tumour Biology 33: 2173-2183.
-
(2012)
Tumour Biology
, vol.33
, pp. 2173-2183
-
-
Vangipuram, S.D.1
Buck, S.A.2
Lyman, W.D.3
-
115
-
-
73649145223
-
Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion
-
3378144 1:CAS:528:DC%2BD1MXhsVSltL%2FE 20049737
-
Varnat, F., A. Duquet, M. Malerba, M. Zbinden, C. Mas, P. Gervaz, I. Ruiz, and A. Altaba. 2009. Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion. EMBO Molecular Medicine 1: 338-351.
-
(2009)
EMBO Molecular Medicine
, vol.1
, pp. 338-351
-
-
Varnat, F.1
Duquet, A.2
Malerba, M.3
Zbinden, M.4
Mas, C.5
Gervaz, P.6
Ruiz, I.7
Altaba, A.8
-
116
-
-
84865635727
-
Sensitization of pancreatic cancer stem cells to gemcitabine by Chk1 inhibition
-
3394194 1:CAS:528:DC%2BC38XhtVCitLvF 22787433
-
Venkatesha, V.A., L.A. Parsels, J.D. Parsels, L. Zhao, S.D. Zabludoff, D.M. Simeone, J. Maybaum, T.S. Lawrence, and M.A. Morgan. 2012. Sensitization of pancreatic cancer stem cells to gemcitabine by Chk1 inhibition. Neoplasia 14: 519-525.
-
(2012)
Neoplasia
, vol.14
, pp. 519-525
-
-
Venkatesha, V.A.1
Parsels, L.A.2
Parsels, J.D.3
Zhao, L.4
Zabludoff, S.D.5
Simeone, D.M.6
Maybaum, J.7
Lawrence, T.S.8
Morgan, M.A.9
-
117
-
-
84866410772
-
Regulation of self-renewal in normal and cancer stem cells
-
1:CAS:528:DC%2BC38XhtlKjtLrI 22846222
-
Verga Falzacappa, M.V., C. Ronchini, L.B. Reavie, and P.G. Pelicci. 2012. Regulation of self-renewal in normal and cancer stem cells. The FEBS Journal 279: 3559-3572.
-
(2012)
The FEBS Journal
, vol.279
, pp. 3559-3572
-
-
Verga Falzacappa, M.V.1
Ronchini, C.2
Reavie, L.B.3
Pelicci, P.G.4
-
118
-
-
72949104153
-
Twist modulates breast cancer stem cells by transcriptional regulation of CD24 expression
-
2794513 1:CAS:528:DC%2BD1MXhsFejurjL 20019840
-
Vesuna, F., A. Lisok, B. Kimble, and V. Raman. 2009. Twist modulates breast cancer stem cells by transcriptional regulation of CD24 expression. Neoplasia 11: 1318-1328.
-
(2009)
Neoplasia
, vol.11
, pp. 1318-1328
-
-
Vesuna, F.1
Lisok, A.2
Kimble, B.3
Raman, V.4
-
119
-
-
84869102655
-
The emerging role of Polycomb repressors in the response to DNA damage
-
1:CAS:528:DC%2BC38XhslKls7jP 23104738
-
Vissers, J.H., M. Van Lohuizen, and E. Citterio. 2012. The emerging role of Polycomb repressors in the response to DNA damage. Journal of Cell Science 125: 3939-3948.
-
(2012)
Journal of Cell Science
, vol.125
, pp. 3939-3948
-
-
Vissers, J.H.1
Van Lohuizen, M.2
Citterio, E.3
-
120
-
-
70349238733
-
Inhibition of the hedgehog pathway in advanced basal-cell carcinoma
-
Von Hoff, D.D., P.M. Lorusso, C.M. Rudin, J.C. Reddy, R.L. Yauch, R. Tibes, G.J. Weiss, M.J. Borad, C.L. Hann, J.R. Brahmer, H.M. Mackey, B.L. Lum, W.C. Darbonne, J.C. Marsters Jr, F.J. De Sauvage, and J.A. Low. 2009. Inhibition of the hedgehog pathway in advanced basal-cell carcinoma. The New England Journal of Medicine 361: 1164-1172.
-
(2009)
The New England Journal of Medicine
, vol.361
, pp. 1164-1172
-
-
Von Hoff, D.D.1
Lorusso, P.M.2
Rudin, C.M.3
Reddy, J.C.4
Yauch, R.L.5
Tibes, R.6
Weiss, G.J.7
Borad, M.J.8
Hann, C.L.9
Brahmer, J.R.10
Mackey, H.M.11
Lum, B.L.12
Darbonne, W.C.13
Marsters, Jr.J.C.14
De Sauvage, F.J.15
Low, J.A.16
-
121
-
-
84868116065
-
Chk1 knockdown confers radiosensitization in prostate cancer stem cells
-
1:CAS:528:DC%2BC38XhvFShsrrN 23027394
-
Wang, X., Z. Ma, Z. Xiao, H. Liu, Z. Dou, X. Feng, and H. Shi. 2012. Chk1 knockdown confers radiosensitization in prostate cancer stem cells. Oncology Reports 28: 2247-2254.
-
(2012)
Oncology Reports
, vol.28
, pp. 2247-2254
-
-
Wang, X.1
Ma, Z.2
Xiao, Z.3
Liu, H.4
Dou, Z.5
Feng, X.6
Shi, H.7
-
122
-
-
84908599867
-
Caveolin-1 mediates chemoresistance in breast cancer stem cells via beta-catenin/ABCG2 signaling pathway
-
25085904
-
Wang, Z., N. Wang, W. Li, P. Liu, Q. Chen, H. Situ, S. Zhong, L. Guo, Y. Lin, J. Shen, and J. Chen. 2014. Caveolin-1 mediates chemoresistance in breast cancer stem cells via beta-catenin/ABCG2 signaling pathway. Carcinogenesis 35: 2346-2356.
-
(2014)
Carcinogenesis
, vol.35
, pp. 2346-2356
-
-
Wang, Z.1
Wang, N.2
Li, W.3
Liu, P.4
Chen, Q.5
Situ, H.6
Zhong, S.7
Guo, L.8
Lin, Y.9
Shen, J.10
Chen, J.11
-
123
-
-
66349110796
-
Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma
-
1:CAS:528:DC%2BD1MXmsFGlur8%3D 19487286
-
Ward, R.J., L. Lee, K. Graham, T. Satkunendran, K. Yoshikawa, E. Ling, L. Harper, R. Austin, E. Nieuwenhuis, I.D. Clarke, C.C. Hui, and P.B. Dirks. 2009. Multipotent CD15+ cancer stem cells in patched-1-deficient mouse medulloblastoma. Cancer Research 69: 4682-4690.
-
(2009)
Cancer Research
, vol.69
, pp. 4682-4690
-
-
Ward, R.J.1
Lee, L.2
Graham, K.3
Satkunendran, T.4
Yoshikawa, K.5
Ling, E.6
Harper, L.7
Austin, R.8
Nieuwenhuis, E.9
Clarke, I.D.10
Hui, C.C.11
Dirks, P.B.12
-
124
-
-
84905454413
-
ABCB5 maintains melanoma-initiating cells through a proinflammatory cytokine signaling circuit
-
1:CAS:528:DC%2BC2cXht1GntrvN 24934811
-
Wilson, B.J., K.R. Saab, J. Ma, T. Schatton, P. Putz, Q. Zhan, G.F. Murphy, M. Gasser, A.M. Waaga-Gasser, N.Y. Frank, and M.H. Frank. 2014. ABCB5 maintains melanoma-initiating cells through a proinflammatory cytokine signaling circuit. Cancer Research 74: 4196-4207.
-
(2014)
Cancer Research
, vol.74
, pp. 4196-4207
-
-
Wilson, B.J.1
Saab, K.R.2
Ma, J.3
Schatton, T.4
Putz, P.5
Zhan, Q.6
Murphy, G.F.7
Gasser, M.8
Waaga-Gasser, A.M.9
Frank, N.Y.10
Frank, M.H.11
-
125
-
-
0023894783
-
The hazard of accelerated tumor clonogen repopulation during radiotherapy
-
1:STN:280:DyaL1c3mvFamsw%3D%3D 3390344
-
Withers, H.R., J.M. Taylor, and B. Maciejewski. 1988. The hazard of accelerated tumor clonogen repopulation during radiotherapy. Acta Oncologica 27: 131-146.
-
(1988)
Acta Oncologica
, vol.27
, pp. 131-146
-
-
Withers, H.R.1
Taylor, J.M.2
Maciejewski, B.3
-
126
-
-
49249122615
-
Wnt/beta-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells
-
1:CAS:528:DC%2BD1cXmsFKmur8%3D 18519688
-
Yang, W., H.X. Yan, L. Chen, Q. Liu, Y.Q. He, L.X. Yu, S.H. Zhang, D.D. Huang, L. Tang, X.N. Kong, C. Chen, S.Q. Liu, M.C. Wu, and H.Y. Wang. 2008. Wnt/beta-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells. Cancer Research 68: 4287-4295.
-
(2008)
Cancer Research
, vol.68
, pp. 4287-4295
-
-
Yang, W.1
Yan, H.X.2
Chen, L.3
Liu, Q.4
He, Y.Q.5
Yu, L.X.6
Zhang, S.H.7
Huang, D.D.8
Tang, L.9
Kong, X.N.10
Chen, C.11
Liu, S.Q.12
Wu, M.C.13
Wang, H.Y.14
-
127
-
-
78650003931
-
Beta-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells
-
1:CAS:528:DC%2BC3cXhsFGhsbvF 21156284
-
Yeung, J., M.T. Esposito, A. Gandillet, B.B. Zeisig, E. Griessinger, D. Bonnet, and C.W. So. 2010. beta-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells. Cancer Cell 18: 606-618.
-
(2010)
Cancer Cell
, vol.18
, pp. 606-618
-
-
Yeung, J.1
Esposito, M.T.2
Gandillet, A.3
Zeisig, B.B.4
Griessinger, E.5
Bonnet, D.6
So, C.W.7
-
128
-
-
80052841288
-
The phenotypic radiation resistance of CD44+/CD24(-or low) breast cancer cells is mediated through the enhanced activation of ATM signaling
-
3174160 1:CAS:528:DC%2BC3MXht1OmsrjK 21935375
-
Yin, H., and J. Glass. 2011. The phenotypic radiation resistance of CD44+/CD24(-or low) breast cancer cells is mediated through the enhanced activation of ATM signaling. PLoS One 6: e24080.
-
(2011)
PLoS One
, vol.6
, pp. 24080
-
-
Yin, H.1
Glass, J.2
-
129
-
-
52949139387
-
AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies
-
1:CAS:528:DC%2BD1cXhtFSmsL7O 18790776
-
Zabludoff, S.D., C. Deng, M.R. Grondine, A.M. Sheehy, S. Ashwell, B.L. Caleb, S. Green, H.R. Haye, C.L. Horn, J.W. Janetka, D. Liu, E. Mouchet, S. Ready, J.L. Rosenthal, C. Queva, G.K. Schwartz, K.J. Taylor, A.N. Tse, G.E. Walker, and A.M. White. 2008. AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies. Molecular Cancer Therapeutics 7: 2955-2966.
-
(2008)
Molecular Cancer Therapeutics
, vol.7
, pp. 2955-2966
-
-
Zabludoff, S.D.1
Deng, C.2
Grondine, M.R.3
Sheehy, A.M.4
Ashwell, S.5
Caleb, B.L.6
Green, S.7
Haye, H.R.8
Horn, C.L.9
Janetka, J.W.10
Liu, D.11
Mouchet, E.12
Ready, S.13
Rosenthal, J.L.14
Queva, C.15
Schwartz, G.K.16
Taylor, K.J.17
Tse, A.N.18
Walker, G.E.19
White, A.M.20
more..
-
130
-
-
84886675130
-
Expression of potential cancer stem cell marker ABCG2 is associated with malignant behaviors of hepatocellular carcinoma
-
3806359 24194752
-
Zhang, G., Z. Wang, W. Luo, H. Jiao, J. Wu, and C. Jiang. 2013. Expression of potential cancer stem cell marker ABCG2 is associated with malignant behaviors of hepatocellular carcinoma. Gastroenterology Research and Practice 2013: 782581.
-
(2013)
Gastroenterology Research and Practice
, vol.2013
, pp. 782581
-
-
Zhang, G.1
Wang, Z.2
Luo, W.3
Jiao, H.4
Wu, J.5
Jiang, C.6
-
131
-
-
64749091867
-
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
-
2946231 1:CAS:528:DC%2BD1MXht1egsrY%3D 19169242
-
Zhao, C., A. Chen, C.H. Jamieson, M. Fereshteh, A. Abrahamsson, J. Blum, H.Y. Kwon, J. Kim, J.P. Chute, D. Rizzieri, M. Munchhof, T. Vanarsdale, P.A. Beachy, and T. Reya. 2009. Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia. Nature 458: 776-779.
-
(2009)
Nature
, vol.458
, pp. 776-779
-
-
Zhao, C.1
Chen, A.2
Jamieson, C.H.3
Fereshteh, M.4
Abrahamsson, A.5
Blum, J.6
Kwon, H.Y.7
Kim, J.8
Chute, J.P.9
Rizzieri, D.10
Munchhof, M.11
Vanarsdale, T.12
Beachy, P.A.13
Reya, T.14
|