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Volumn 56, Issue 6, 2013, Pages 495-502

A drug from poison: How the therapeutic effect of arsenic trioxide on acute promyelocytic leukemia was discovered

Author keywords

acute promyelocytic leukemia; arsenic trioxide; leukemia

Indexed keywords

ANTINEOPLASTIC AGENT; ARSENIC TRIOXIDE; ORGANOARSENIC DERIVATIVE; OXIDE;

EID: 84878785804     PISSN: 16747305     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11427-013-4487-z     Document Type: Review
Times cited : (44)

References (66)
  • 1
    • 0014347896 scopus 로고
    • Arabinosyl cytosine: a useful agent in the treatment of acute leukemia in adults
    • Ellison R R, Holland J F, Weil M, et al. Arabinosyl cytosine: a useful agent in the treatment of acute leukemia in adults. Blood, 1968, 32: 507-523.
    • (1968) Blood , vol.32 , pp. 507-523
    • Ellison, R.R.1    Holland, J.F.2    Weil, M.3
  • 2
    • 0014675775 scopus 로고
    • Daunorubicin in the treatment of acute myelocytic leukaemia
    • Boiron M, Weil M, Jacquillat C, et al. Daunorubicin in the treatment of acute myelocytic leukaemia. Lancet, 1969, 293: 330-333.
    • (1969) Lancet , vol.293 , pp. 330-333
    • Boiron, M.1    Weil, M.2    Jacquillat, C.3
  • 3
    • 0015605395 scopus 로고
    • Acute promyelocytic leukemia: results of treatment by daunorubicin
    • Bernard J, Weil M, Boiron M, et al. Acute promyelocytic leukemia: results of treatment by daunorubicin. Blood, 1973, 41: 489-496.
    • (1973) Blood , vol.41 , pp. 489-496
    • Bernard, J.1    Weil, M.2    Boiron, M.3
  • 4
    • 0016008518 scopus 로고
    • Treatment of acute granulocytic leukemias
    • Bernard J, Weil M, Jacquillat C I. Treatment of acute granulocytic leukemias. Ann Rev Med, 1974, 25: 39-50.
    • (1974) Ann Rev Med , vol.25 , pp. 39-50
    • Bernard, J.1    Weil, M.2    Jacquillat, C.I.3
  • 5
    • 84988842269 scopus 로고
    • Preliminary clinical observations of six cases of leukemia treated by "Ailin solution" (in Chinese) 1)
    • Zhang T D, Zhang P F, Wang S R, et al. Preliminary clinical observations of six cases of leukemia treated by "Ailin solution" (in Chinese) 1). Med Pharm Heilongjiang, 1973, (3): 66-67.
    • (1973) Med Pharm Heilongjiang , pp. 66-67
    • Zhang, T.D.1    Zhang, P.F.2    Wang, S.R.3
  • 6
    • 84878798754 scopus 로고
    • Therapeutic observations of 17 cases leukemia treated with Ailin No.1 and dialectic theory (in Chinese)
    • Departments of Traditional Chinese MedicineLaboratory Medicine of the First Affiliated Hospital of Harbin Medical University
    • Departments of Traditional Chinese Medicine and Laboratory Medicine of the First Affiliated Hospital of Harbin Medical University. Therapeutic observations of 17 cases leukemia treated with Ailin No. 1 and dialectic theory (in Chinese). J Harbin Med Univ, 1974, (2): 25-30.
    • (1974) J Harbin Med Univ , pp. 25-30
  • 7
    • 84892678772 scopus 로고
    • A report on long term survival of two cases of acute granulocytic leukemia (in Chinese)
    • Rong F X, Zhang T D. A report on long term survival of two cases of acute granulocytic leukemia (in Chinese). J New Med Pharm, 1979, (6): 31-34.
    • (1979) J New Med Pharm , pp. 31-34
    • Rong, F.X.1    Zhang, T.D.2
  • 8
    • 85082835324 scopus 로고
    • Treatment of acute granulocytic leukemia by Ailin No.1 and dialectic theory (in Chinese)
    • Zhang T D, Rong F X. Treatment of acute granulocytic leukemia by Ailin No. 1 and dialectic theory (in Chinese). Med Pharm Heilongjiang, 1979, (4): 7-11.
    • (1979) Med Pharm Heilongjiang , pp. 7-11
    • Zhang, T.D.1    Rong, F.X.2
  • 9
    • 0023631093 scopus 로고
    • All-trans retinoic acid with or without low dose cytosine arabinoside in acute promyelocytic leukemia: report of six cases (in Chinese)
    • Huang M E, Ye Y C, Chen S R, et al. All-trans retinoic acid with or without low dose cytosine arabinoside in acute promyelocytic leukemia: report of six cases (in Chinese). Chin Med J, 1987, 100: 949-953.
    • (1987) Chin Med J , vol.100 , pp. 949-953
    • Huang, M.E.1    Ye, Y.C.2    Chen, S.R.3
  • 10
    • 0023752982 scopus 로고
    • Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
    • Huang M E, Ye Y C, Chen S R, et al. Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood, 1988, 72: 567-572.
    • (1988) Blood , vol.72 , pp. 567-572
    • Huang, M.E.1    Ye, Y.C.2    Chen, S.R.3
  • 11
    • 61949441174 scopus 로고    scopus 로고
    • Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet
    • Sanz M A, Grimwade D, Tallman M S, et al. Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet. Blood, 2009, 113: 1875-1891.
    • (2009) Blood , vol.113 , pp. 1875-1891
    • Sanz, M.A.1    Grimwade, D.2    Tallman, M.S.3
  • 12
    • 73949097021 scopus 로고    scopus 로고
    • How I treat acute promyelocytic leukemia
    • Tallman M S, Altman J K. How I treat acute promyelocytic leukemia. Blood, 2009, 114: 51260-51235.
    • (2009) Blood , vol.114 , pp. 51235-51260
    • Tallman, M.S.1    Altman, J.K.2
  • 13
    • 79952079063 scopus 로고    scopus 로고
    • Modern approaches to treating acute promyelocytic leukemia
    • Sanz M A, Lo-Coco F. Modern approaches to treating acute promyelocytic leukemia. J Clin Oncol, 2011, 29: 495-503.
    • (2011) J Clin Oncol , vol.29 , pp. 495-503
    • Sanz, M.A.1    Lo-Coco, F.2
  • 14
    • 77958456360 scopus 로고    scopus 로고
    • Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710
    • Powell B L, Moser B, Stock W, et al. Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710. Blood, 2010, 116: 3751-3757.
    • (2010) Blood , vol.116 , pp. 3751-3757
    • Powell, B.L.1    Moser, B.2    Stock, W.3
  • 15
    • 79960269272 scopus 로고    scopus 로고
    • Newly diagnosed acute promyelocytic leukemia: arsenic moves front and center
    • Estey E H. Newly diagnosed acute promyelocytic leukemia: arsenic moves front and center. J Clin Oncol, 2011, 29: 2743-2746.
    • (2011) J Clin Oncol , vol.29 , pp. 2743-2746
    • Estey, E.H.1
  • 16
    • 0023731397 scopus 로고
    • History of the treatment of chronic myelocytic leukemia
    • Sears D A. History of the treatment of chronic myelocytic leukemia. Am J Med Sci, 1988, 296: 85-86.
    • (1988) Am J Med Sci , vol.296 , pp. 85-86
    • Sears, D.A.1
  • 17
    • 0027216039 scopus 로고
    • A history of the use of arsenicals in man
    • Jolliffe D M. A history of the use of arsenicals in man. J Royal Soc Med, 1993, 86: 287-289.
    • (1993) J Royal Soc Med , vol.86 , pp. 287-289
    • Jolliffe, D.M.1
  • 18
    • 84892674264 scopus 로고
    • Leukemia: clinical analysis of 49 cases (in Chinese)
    • Guan J R. Leukemia: clinical analysis of 49 cases (in Chinese). Heilongjiang Med, 1958, (2): 22-34.
    • (1958) Heilongjiang Med , pp. 22-34
    • Guan, J.R.1
  • 19
    • 84892670109 scopus 로고
    • Preliminary observations of the therapeutic effect of the traditional Chinese medicine "55" on leukemia (in Chinese)
    • Gu D X. Preliminary observations of the therapeutic effect of the traditional Chinese medicine "55" on leukemia (in Chinese). Harbin J Trad Chin Med, 1964, 5: 24.
    • (1964) Harbin J Trad Chin Med , vol.5 , pp. 24
    • Gu, D.X.1
  • 21
    • 84878813257 scopus 로고
    • Treatment of leukemia by traditional Chinese medicine (in Chinese)
    • Hematology Group of the Department of Internal Medicine at Xiyuan Hospital of the Chinese Academy of Traditional Medicine
    • Hematology Group of the Department of Internal Medicine at Xiyuan Hospital of the Chinese Academy of Traditional Medicine. Treatment of leukemia by traditional Chinese medicine (in Chinese). Guangdong Med, 1974, (5): 31-37.
    • (1974) Guangdong Med , pp. 31-37
  • 22
    • 44449097884 scopus 로고    scopus 로고
    • Research on Qinghuang San treatment of leukemia (in Chinese)
    • Zhou A X. Research on Qinghuang San treatment of leukemia (in Chinese). Chin J Integrat Trad West Med, 1998, 18: 582-583.
    • (1998) Chin J Integrat Trad West Med , vol.18 , pp. 582-583
    • Zhou, A.X.1
  • 23
    • 84878807838 scopus 로고
    • A clinical summary of 73 cases treated by Ailin No.1 combined with the dialectic theory (in Chinese)
    • Department of Traditional Chinese Medicine of the First Affiliated Hospital of Harbin Medical University
    • Department of Traditional Chinese Medicine of the First Affiliated Hospital of Harbin Medical University (Supervisor: Zhang T D. Writers: Li Y S, Hu X C. Participants: Li M X, Zhang P F, Rong F X, et al.). A clinical summary of 73 cases treated by Ailin No. 1 combined with the dialectic theory (in Chinese). Chin Med Pharm Heilongjiang, 1981, (4): 28-30.
    • (1981) Chin Med Pharm Heilongjiang , pp. 28-30
  • 24
    • 0020155833 scopus 로고
    • Comments on questions about designing clinical research with combined Chinese and Western medicine (in Chinese)
    • Zhang T D. Comments on questions about designing clinical research with combined Chinese and Western medicine (in Chinese). J Integrat Trad Chin West Med, 1982, 2: 180-181.
    • (1982) J Integrat Trad Chin West Med , vol.2 , pp. 180-181
    • Zhang, T.D.1
  • 25
    • 84892680077 scopus 로고
    • Understanding and treatment of leukemia by Chinese medicine (in Chinese)
    • Zhang T D. Understanding and treatment of leukemia by Chinese medicine (in Chinese). J Trad Chin Med, 1983, (3): 71-74.
    • (1983) J Trad Chin Med , pp. 71-74
    • Zhang, T.D.1
  • 26
    • 0021298594 scopus 로고
    • Clinical findings and experimental research of Ailin No. 1 in treating acute granuloleukemia (in Chinese)
    • Zhang T D, Li Y S. Clinical findings and experimental research of Ailin No. 1 in treating acute granuloleukemia (in Chinese). J Integrat Trad Chin West Med, 1984, 4: 19-20.
    • (1984) J Integrat Trad Chin West Med , vol.4 , pp. 19-20
    • Zhang, T.D.1    Li, Y.S.2
  • 27
    • 84892680511 scopus 로고
    • Diagnosis and treatment of acute non-lymphatic leukemia (in Chinese)
    • Zhang T D. Diagnosis and treatment of acute non-lymphatic leukemia (in Chinese). J Integrat Trad Chin West Med, 1985, 5: 713.
    • (1985) J Integrat Trad Chin West Med , vol.5 , pp. 713
    • Zhang, T.D.1
  • 28
    • 84892673009 scopus 로고
    • A report on 16 acute promyelocytic leukemia cases of long term survival treated by Ailin No.1 in combination with traditional Chinese dialectic theories (in Chinese)
    • Sun H D, Ma L, Hu X C, et al. A report on 16 acute promyelocytic leukemia cases of long term survival treated by Ailin No. 1 in combination with traditional Chinese dialectic theories (in Chinese). Inf Trad Chin Med Pharm, 1991, (6): 39-41.
    • (1991) Inf Trad Chin Med Pharm , pp. 39-41
    • Sun, H.D.1    Ma, L.2    Hu, X.C.3
  • 29
    • 0000210796 scopus 로고
    • Ailin I treated 32 cases of acute promyelocytic leukemia (in Chinese)
    • Sun H D, Ma L, Hu X C, et al. Ailin I treated 32 cases of acute promyelocytic leukemia (in Chinese). Chin J Integrat Chin West Med, 1992, 12: 170-172.
    • (1992) Chin J Integrat Chin West Med , vol.12 , pp. 170-172
    • Sun, H.D.1    Ma, L.2    Hu, X.C.3
  • 30
    • 85015237866 scopus 로고
    • 3) treatment of 117 cases of acute promyelocytic leukemia: clinical observations and mechanistic investigations (in Chinese)
    • 3) treatment of 117 cases of acute promyelocytic leukemia: clinical observations and mechanistic investigations (in Chinese). J Harbin Med Univ, 1995, 29: 243.
    • (1995) J Harbin Med Univ , vol.29 , pp. 243
    • Zhang, P.1    Wang, S.Y.2    Hu, L.H.3
  • 31
    • 0001837016 scopus 로고    scopus 로고
    • Treatment of 72 cases of acute promyelocytic leukemia with intravenous arsenic trioxide (in Chinese)
    • Zhang P, Wang S Y, Hu L H, et al. Treatment of 72 cases of acute promyelocytic leukemia with intravenous arsenic trioxide (in Chinese). Chin J Hematol, 1996, 17: 58-62.
    • (1996) Chin J Hematol , vol.17 , pp. 58-62
    • Zhang, P.1    Wang, S.Y.2    Hu, L.H.3
  • 32
    • 0017782474 scopus 로고
    • Continuous growth and differentiation of human myeloid leukemic cells in suspension culture
    • Collins S J, Gallo R C, Gallagher R E. Continuous growth and differentiation of human myeloid leukemic cells in suspension culture. Nature, 1977, 270: 347-349.
    • (1977) Nature , vol.270 , pp. 347-349
    • Collins, S.J.1    Gallo, R.C.2    Gallagher, R.E.3
  • 33
    • 0001679798 scopus 로고
    • Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid
    • Breitman T R, Selonick S E, Collins S J. Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid. Proc Natl Acad Sci USA, 1980, 70: 2936-2940.
    • (1980) Proc Natl Acad Sci USA , vol.70 , pp. 2936-2940
    • Breitman, T.R.1    Selonick, S.E.2    Collins, S.J.3
  • 34
    • 0019407488 scopus 로고
    • Terminal differentiation of human promyelocytic leukemic cells in primary culture in response to retinoic acid
    • Breitman T R, Collins S J, Keene B R. Terminal differentiation of human promyelocytic leukemic cells in primary culture in response to retinoic acid. Blood, 1981, 57: 1000-1004.
    • (1981) Blood , vol.57 , pp. 1000-1004
    • Breitman, T.R.1    Collins, S.J.2    Keene, B.R.3
  • 35
    • 0020359103 scopus 로고
    • Induction of differentiation of the human histiocytic lymphoma cell line U-937 by retinoic acid and cyclic adenosine 3′: 5′-monophosphate-inducing agents
    • Olsson I L, Breitman T R. Induction of differentiation of the human histiocytic lymphoma cell line U-937 by retinoic acid and cyclic adenosine 3′: 5′-monophosphate-inducing agents. C Cancer Res, 1982, 42: 3924-3927.
    • (1982) C Cancer Res , vol.42 , pp. 3924-3927
    • Olsson, I.L.1    Breitman, T.R.2
  • 36
    • 0020702267 scopus 로고
    • Induction of differentiation of human acute non-lymphocytic leukemia cells in primary culture by inducers of differentiation of human myeloid leukemia cell line HL-60
    • Honma Y, Fujita Y, Kasukabe T, et al. Induction of differentiation of human acute non-lymphocytic leukemia cells in primary culture by inducers of differentiation of human myeloid leukemia cell line HL-60. Eur J Cancer Clin Oncol, 1983, 19: 251-261.
    • (1983) Eur J Cancer Clin Oncol , vol.19 , pp. 251-261
    • Honma, Y.1    Fujita, Y.2    Kasukabe, T.3
  • 37
    • 0020506009 scopus 로고
    • Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications
    • Koeffler H P. Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications. Blood, 1983, 62: 709-721.
    • (1983) Blood , vol.62 , pp. 709-721
    • Koeffler, H.P.1
  • 38
    • 0021043763 scopus 로고
    • Retinoic acid treatment of acute promyelocytic leukemia: in vitro and in vivo observations
    • Flynn P, Miller W, Weisdorf D, et al. Retinoic acid treatment of acute promyelocytic leukemia: in vitro and in vivo observations. Blood, 1983, 62: 1211-1217.
    • (1983) Blood , vol.62 , pp. 1211-1217
    • Flynn, P.1    Miller, W.2    Weisdorf, D.3
  • 39
    • 0021272896 scopus 로고
    • Probable in vivo induction of differentiation by retinoic acid acid of promyelocytes in acute promyelocytic leukemia
    • Nilsson B. Probable in vivo induction of differentiation by retinoic acid acid of promyelocytes in acute promyelocytic leukemia. British J Haematol, 1984, 57: 365-371.
    • (1984) British J Haematol , vol.57 , pp. 365-371
    • Nilsson, B.1
  • 40
    • 0022642215 scopus 로고
    • Retinoic acid as antileukemic therapy in a patient with acute promyelocytic leukemia and Aspergillus pneumonia
    • Daenen S, Vellenga E, van Dobbenbugh O A, et al. Retinoic acid as antileukemic therapy in a patient with acute promyelocytic leukemia and Aspergillus pneumonia. Blood, 1986, 67: 559-561.
    • (1986) Blood , vol.67 , pp. 559-561
    • Daenen, S.1    Vellenga, E.2    van Dobbenbugh, O.A.3
  • 41
    • 0022643577 scopus 로고
    • The role of 13-cis retinoic acid in the remission induction of a patient with acute promyelocytic leukemia
    • Fontana J A, Roger I S, Durham J P. The role of 13-cis retinoic acid in the remission induction of a patient with acute promyelocytic leukemia. Cancer, 1986, 57: 209-217.
    • (1986) Cancer , vol.57 , pp. 209-217
    • Fontana, J.A.1    Roger, I.S.2    Durham, J.P.3
  • 42
    • 0024423303 scopus 로고
    • Retinoic acid therapy for promyelocytic leukemia
    • Chomienne C, Ballerini P, Balitrand N, et al. Retinoic acid therapy for promyelocytic leukemia. Lancet, 1989, 334: 746-747.
    • (1989) Lancet , vol.334 , pp. 746-747
    • Chomienne, C.1    Ballerini, P.2    Balitrand, N.3
  • 43
    • 0025201879 scopus 로고
    • All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results
    • Castaigne S, Chomienne C, Daniel M T, et al. All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results. Blood, 1990, 76: 1704-1709.
    • (1990) Blood , vol.76 , pp. 1704-1709
    • Castaigne, S.1    Chomienne, C.2    Daniel, M.T.3
  • 44
    • 0026040363 scopus 로고
    • A clinical and experimental study on all-trans retinoic acid treated acute promyelocytic leukemia patients
    • Chen Z X, Xue Y Q, Zhang R, et al. A clinical and experimental study on all-trans retinoic acid treated acute promyelocytic leukemia patients. Blood, 1991, 78: 1413-1419.
    • (1991) Blood , vol.78 , pp. 1413-1419
    • Chen, Z.X.1    Xue, Y.Q.2    Zhang, R.3
  • 45
    • 0025882306 scopus 로고
    • Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid)
    • Warrell Jr R P, Frankel S T, Miller Jr W H, et al. Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid). N Engl J Med, 1991, 324: 1385-1393.
    • (1991) N Engl J Med , vol.324 , pp. 1385-1393
    • Warrell Jr., R.P.1    Frankel, S.T.2    Miller Jr., W.H.3
  • 46
    • 0030923479 scopus 로고    scopus 로고
    • All-trans-retinoic acid in acute promyelocytic leukemia
    • Tallman M S, Andersen J W, Schiffer C A, et al. All-trans-retinoic acid in acute promyelocytic leukemia. N Engl J Med, 1997, 337: 1021-1028.
    • (1997) N Engl J Med , vol.337 , pp. 1021-1028
    • Tallman, M.S.1    Andersen, J.W.2    Schiffer, C.A.3
  • 47
    • 84892674508 scopus 로고
    • Anti-cancer effect of Ailin No. 1 on leukemic cells of acute promyelocytic leukemia patients (in Chinese)
    • Duan J X, Xin X M, Wang F Q, et al. Anti-cancer effect of Ailin No. 1 on leukemic cells of acute promyelocytic leukemia patients (in Chinese). Pract J Oncol, 1992, (2): 29-30.
    • (1992) Pract J Oncol , pp. 29-30
    • Duan, J.X.1    Xin, X.M.2    Wang, F.Q.3
  • 48
    • 0001968572 scopus 로고
    • Clinical study on the treatment of APL mainly with composite Indigo Naturalis tablets (in Chinese)
    • Huang S L, Guo A X, Xiang Y, et al. Clinical study on the treatment of APL mainly with composite Indigo Naturalis tablets (in Chinese). Chin J Hematol, 1995, 16: 26.
    • (1995) Chin J Hematol , vol.16 , pp. 26
    • Huang, S.L.1    Guo, A.X.2    Xiang, Y.3
  • 49
    • 0010740572 scopus 로고    scopus 로고
    • 3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR α/PML proteins
    • 3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR α/PML proteins. Blood, 1996, 88: 1052-1061.
    • (1996) Blood , vol.88 , pp. 1052-1061
    • Chen, G.Q.1    Zhu, J.2    Shi, X.G.3
  • 50
    • 84892676975 scopus 로고    scopus 로고
    • A case of APL survival of 20 years with treatment by Ailin I (in Chinese)
    • Xu J S, Duan J M, Xu Y, et al. A case of APL survival of 20 years with treatment by Ailin I (in Chinese). Chin J Hematol, 1997, 18: 476.
    • (1997) Chin J Hematol , vol.18 , pp. 476
    • Xu, J.S.1    Duan, J.M.2    Xu, Y.3
  • 51
    • 0030610686 scopus 로고    scopus 로고
    • 3 exerts dose-dependent dual effects on APL cells
    • 3 exerts dose-dependent dual effects on APL cells. Blood, 1997, 89: 3345-3353.
    • (1997) Blood , vol.89 , pp. 3345-3353
    • Chen, G.Q.1    Shi, X.G.2    Tang, W.3
  • 52
    • 0030610687 scopus 로고    scopus 로고
    • 3) in the treatment of acute promyelocytic leukemia (APL), II: clinical efficacy and pharmacokinetics in relapsed patients
    • 3) in the treatment of acute promyelocytic leukemia (APL), II: clinical efficacy and pharmacokinetics in relapsed patients. Blood, 1997, 89: 3354-3360.
    • (1997) Blood , vol.89 , pp. 3354-3360
    • Shen, Z.X.1    Chen, G.Q.2    Ni, J.H.3
  • 53
    • 0032487923 scopus 로고    scopus 로고
    • Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide
    • Soignet S L, Maslak P, Wang Z G, et al. Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide. N Engl J Med, 1998, 339: 1341-1348.
    • (1998) N Engl J Med , vol.339 , pp. 1341-1348
    • Soignet, S.L.1    Maslak, P.2    Wang, Z.G.3
  • 55
    • 84892680811 scopus 로고    scopus 로고
    • 1998). Mechanisms and prospects of arsenic treatment of acute promyelocytic leukemia (in Chinese
    • Chen G Q, Chen S J, Wang Z Y, et al. (1998). Mechanisms and prospects of arsenic treatment of acute promyelocytic leukemia (in Chinese). Chin J Integrat Trad Chin West Med, 1998, 18: 581-582.
    • (1998) Chin J Integrat Trad Chin West Med , vol.18 , pp. 581-582
    • Chen, G.Q.1    Chen, S.J.2    Wang, Z.Y.3
  • 56
    • 0029772547 scopus 로고    scopus 로고
    • Cancer research: ancient remedy performs new tricks
    • Mervis J. Cancer research: ancient remedy performs new tricks. Science, 1996, 273: 578.
    • (1996) Science , vol.273 , pp. 578
    • Mervis, J.1
  • 57
    • 0035969124 scopus 로고    scopus 로고
    • Arsenic trioxide, a therapeutic agent for APL
    • Zhang T D, Chen G Q, Wang Z G, et al. Arsenic trioxide, a therapeutic agent for APL. Oncogene, 2001, 20: 7146-7153.
    • (2001) Oncogene , vol.20 , pp. 7146-7153
    • Zhang, T.D.1    Chen, G.Q.2    Wang, Z.G.3
  • 58
    • 0036715589 scopus 로고    scopus 로고
    • How acute promyelocytic leukaemia revived arsenic
    • Zhu J, Chen Z, Lallemand-Breitenbach V, et al. How acute promyelocytic leukaemia revived arsenic. Nat Rev Cancer, 2001, 2: 705-714.
    • (2001) Nat Rev Cancer , vol.2 , pp. 705-714
    • Zhu, J.1    Chen, Z.2    Lallemand-Breitenbach, V.3
  • 59
    • 41949111045 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: from highly fatal to highly curable
    • Wang Z Y, Chen Z. Acute promyelocytic leukemia: from highly fatal to highly curable. Blood, 2008, 111: 2505-2515.
    • (2008) Blood , vol.111 , pp. 2505-2515
    • Wang, Z.Y.1    Chen, Z.2
  • 60
    • 0033570955 scopus 로고    scopus 로고
    • Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: remission induction, follow-up, and molecular monitoring in 11 newly diagnosed and 47 relapsed acute promyelocytic leukemia patients
    • Niu C, Yan H, Yu T, et al. Studies on treatment of acute promyelocytic leukemia with arsenic trioxide: remission induction, follow-up, and molecular monitoring in 11 newly diagnosed and 47 relapsed acute promyelocytic leukemia patients. Blood, 1999, 94: 3315-3324.
    • (1999) Blood , vol.94 , pp. 3315-3324
    • Niu, C.1    Yan, H.2    Yu, T.3
  • 61
    • 79959473062 scopus 로고    scopus 로고
    • From an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemia
    • Chen S J, Zhou G B, Zhang X W, et al. From an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemia. Blood, 2011, 117: 6425-6437.
    • (2011) Blood , vol.117 , pp. 6425-6437
    • Chen, S.J.1    Zhou, G.B.2    Zhang, X.W.3
  • 63
    • 84055213176 scopus 로고    scopus 로고
    • Oral arsenic trioxide-based maintenance regimens for first complete remission of acute promyelocytic leukemia: a 10-year follow-up study
    • Au W Y, Kumana C R, Lee H K K, et al. Oral arsenic trioxide-based maintenance regimens for first complete remission of acute promyelocytic leukemia: a 10-year follow-up study. Blood, 2011, 118: 6535-6543.
    • (2011) Blood , vol.118 , pp. 6535-6543
    • Au, W.Y.1    Kumana, C.R.2    Lee, H.K.K.3
  • 64
    • 84892672938 scopus 로고
    • Investigation of the dynamics of Ailin No. 1 on human liver cancer cells (in Chinese)
    • Li Y S, Zhang T D, Wang X R, et al. Investigation of the dynamics of Ailin No. 1 on human liver cancer cells (in Chinese). Res Cancer Prevent Treat, 1988, 15: 1-3.
    • (1988) Res Cancer Prevent Treat , vol.15 , pp. 1-3
    • Li, Y.S.1    Zhang, T.D.2    Wang, X.R.3
  • 65
    • 23644444680 scopus 로고    scopus 로고
    • Effect of arsenic trioxide on hepatocellular carcinoma and its mechanistic studies
    • Liu L X, Zhu A L, Chen W, et al. Effect of arsenic trioxide on hepatocellular carcinoma and its mechanistic studies. Chin J Surg, 2005, 43: 33-36.
    • (2005) Chin J Surg , vol.43 , pp. 33-36
    • Liu, L.X.1    Zhu, A.L.2    Chen, W.3
  • 66
    • 84892672000 scopus 로고    scopus 로고
    • Recent status of the effect of arsenic trioxide on colon cancer
    • Guo H X, Chen W, Liu L X, et al. Recent status of the effect of arsenic trioxide on colon cancer. Chin J Integr Trad West Med Dig, 2006, 14: 207-209.
    • (2006) Chin J Integr Trad West Med Dig , vol.14 , pp. 207-209
    • Guo, H.X.1    Chen, W.2    Liu, L.X.3


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