Sonic hedgehog pathway is essential for maintenance of cancer stem-like cells in human gastric cancer

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Song, Zhou ^a   Yue, Wen ^b   Wei, Bo ^a   Wang, Ning ^a   Li, Tao ^a   Guan, Lidong ^b   Shi, Shuangshuang ^b   Zeng, Quan ^b   Pei, Xuetao ^b   Chen, Lin ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; CD24 ANTIGEN; CD44V ANTIGEN; CYCLOPAMINE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 5E1; OXALIPLATIN; PROTEIN PATCHED; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; SHH PROTEIN, HUMAN;

ADHERENT CELL; ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CANCER CELL CULTURE; CANCER STEM CELL; CELL ISOLATION; CELL RENEWAL; CONTROLLED STUDY; DRUG MECHANISM; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MALE; MOUSE; NONHUMAN; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; STOMACH CARCINOGENESIS; TUMOR SEEDING; TUMOR XENOGRAFT; WESTERN BLOTTING; ANIMAL; CELL ADHESION; CELL AGGREGATION; CELL PROLIFERATION; DRUG EFFECT; DRUG RESISTANCE; DRUG SCREENING; METABOLISM; NUDE MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; STOMACH TUMOR; SUBCUTANEOUS TISSUE; TUMOR CELL CULTURE;

ERINACEIDAE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL ADHESION; CELL AGGREGATION; CELL PROLIFERATION; DRUG RESISTANCE, NEOPLASM; HEDGEHOG PROTEINS; HUMANS; MALE; MICE; MICE, NUDE; NEOPLASTIC STEM CELLS; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; SUBCUTANEOUS TISSUE; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79952318891     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017687     Document Type: Article

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