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Volumn 287, Issue 39, 2012, Pages 32800-32824

Hyaluronan-CD44v3 interaction with Oct4-Sox2-Nanog promotes miR-302 expression leading to self-renewal, clonal formation, and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

CANCER STEM CELLS; CELL MARKERS; CELL POPULATIONS; CHROMATIN IMMUNOPRECIPITATION ASSAY; CIS-PLATIN; COMPLEX FORMATIONS; DOWN-REGULATION; HEAD-AND-NECK CANCER; HEAD-AND-NECK SQUAMOUS CELL CARCINOMA; HUMAN HEAD; HYALURONAN; MALIGNANT CANCERS; NUCLEAR TRANSLOCATIONS; PROTEIN ACTIVATION; TARGET FUNCTIONS; TUMOR CELLS; UP-REGULATION;

EID: 84866559462     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.308528     Document Type: Article
Times cited : (245)

References (71)
  • 3
    • 27744482673 scopus 로고    scopus 로고
    • Establishment and characterization of a cisplatin-resistant oral squamous cell carcinoma cell line, H-1R
    • Nakamura, M., Nakatani, K., Uzawa, K., Ono, K., Uesugi, H., and Ogawara, K. (2005) Establishment and characterization of a cisplatin-resistant oral squamous cell carcinoma cell line, H-1R. Oncol. Rep. 14, 1281-1286
    • (2005) Oncol. Rep. , vol.14 , pp. 1281-1286
    • Nakamura, M.1    Nakatani, K.2    Uzawa, K.3    Ono, K.4    Uesugi, H.5    Ogawara, K.6
  • 4
    • 77952488511 scopus 로고    scopus 로고
    • Reduction of hyaluronan-CD44-mediated growth, migration, and cisplatin resistance in head and neck cancer due to inhibition of Rho kinase and PI 3-kinase signaling
    • Torre, C., Wang, S. J., Xia, W., and Bourguignon, L. Y. (2010) Reduction of hyaluronan-CD44-mediated growth, migration, and cisplatin resistance in head and neck cancer due to inhibition of Rho kinase and PI 3-kinase signaling. Arch. Otolaryngol. Head Neck Surg. 136, 493-501
    • (2010) Arch. Otolaryngol. Head Neck Surg. , vol.136 , pp. 493-501
    • Torre, C.1    Wang, S.J.2    Xia, W.3    Bourguignon, L.Y.4
  • 5
    • 79952767543 scopus 로고    scopus 로고
    • Role of hyaluronan-mediated CD44 signaling in head and neck squamous cell carcinoma progression and chemoresistance
    • Wang, S. J., and Bourguignon, L. Y. (2011) Role of hyaluronan-mediated CD44 signaling in head and neck squamous cell carcinoma progression and chemoresistance. Am. J. Pathol. 178, 956-963
    • (2011) Am. J. Pathol. , vol.178 , pp. 956-963
    • Wang, S.J.1    Bourguignon, L.Y.2
  • 6
    • 84855781227 scopus 로고    scopus 로고
    • Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells
    • Bourguignon, L. Y., Earle, C., Wong, G., Spevak, C. C., and Krueger, K. (2012) Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells. Oncogene 31, 149-160
    • (2012) Oncogene , vol.31 , pp. 149-160
    • Bourguignon, L.Y.1    Earle, C.2    Wong, G.3    Spevak, C.C.4    Krueger, K.5
  • 7
    • 34547126428 scopus 로고    scopus 로고
    • The inhibitors of apoptosis (IAPs) as cancer targets
    • Hunter, A. M. (2007) The inhibitors of apoptosis (IAPs) as cancer targets. Apoptosis 12, 1543-1568
    • (2007) Apoptosis , vol.12 , pp. 1543-1568
    • Hunter, A.M.1
  • 8
    • 77954930632 scopus 로고    scopus 로고
    • IAPs. From caspase inhibitors to modulators of NF-κB, inflammation, and cancer
    • Gyrd-Hansen, M., and Meier, P. (2010) IAPs. From caspase inhibitors to modulators of NF-κB, inflammation, and cancer. Nat. Rev. Cancer 10, 561-574
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 561-574
    • Gyrd-Hansen, M.1    Meier, P.2
  • 9
    • 59149085705 scopus 로고    scopus 로고
    • Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates β-catenin signaling and NFκB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cells
    • Bourguignon, L. Y., Xia, W., and Wong, G. (2009) Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates β-catenin signaling and NFκB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cells. J. Biol. Chem. 284, 2657-2671
    • (2009) J. Biol. Chem. , vol.284 , pp. 2657-2671
    • Bourguignon, L.Y.1    Xia, W.2    Wong, G.3
  • 10
    • 34047096557 scopus 로고    scopus 로고
    • Cancer stem cells: Models and concepts
    • DOI 10.1146/annurev.med.58.062105.204854
    • Dalerba, P., Cho, R. W., and Clarke, M. F. (2007) Cancer stem cells. Models and concepts. Annu. Rev. Med. 58, 267-284 (Pubitemid 46706514)
    • (2007) Annual Review of Medicine , vol.58 , pp. 267-284
    • Dalerba, P.1    Cho, R.W.2    Clarke, M.F.3
  • 12
    • 33845364233 scopus 로고    scopus 로고
    • Cancer stem cells and oncology therapeutics
    • Al-Hajj, M. (2007) Cancer stem cells and oncology therapeutics. Curr. Opin. Oncol. 19, 61-64
    • (2007) Curr. Opin. Oncol. , vol.19 , pp. 61-64
    • Al-Hajj, M.1
  • 15
    • 54449085703 scopus 로고    scopus 로고
    • CD44s and CD44v6 expression in head and neck epithelia
    • Mack, B., and Gires, O. (2008) CD44s and CD44v6 expression in head and neck epithelia. PLoS One. 3, e3360
    • (2008) PLoS One. , vol.3
    • Mack, B.1    Gires, O.2
  • 16
    • 68849088549 scopus 로고    scopus 로고
    • CD44 variant isoforms in head and neck squamous cell carcinoma progression
    • Wang, S. J., Wong, G., de Heer, A. M., Xia, W., and Bourguignon, L. Y. (2009) CD44 variant isoforms in head and neck squamous cell carcinoma progression. Laryngoscope 119, 1518-1530
    • (2009) Laryngoscope , vol.119 , pp. 1518-1530
    • Wang, S.J.1    Wong, G.2    De Heer, A.M.3    Xia, W.4    Bourguignon, L.Y.5
  • 18
    • 34548207609 scopus 로고    scopus 로고
    • Association of CD44 V3-containing isoforms with tumor cell growth, migration, matrix metalloproteinase expression, and lymph node metastasis in head and neck cancer
    • DOI 10.1002/hed.20544
    • Wang, S. J., Wreesmann, V. B., and Bourguignon, L. Y. (2007) Association of CD44 V3-containing isoforms with tumor cell growth, migration, matrix metalloproteinase expression, and lymph node metastasis in head and neck cancer. Head Neck 29, 550-558 (Pubitemid 47324771)
    • (2007) Head and Neck , vol.29 , Issue.6 , pp. 550-558
    • Wang, S.J.1    Wreesmann, V.B.2    Bourguignon, L.Y.W.3
  • 20
    • 0033812683 scopus 로고    scopus 로고
    • Hyaluronan. A multifunctional, megadalton, stealth molecule
    • Lee, J. Y., and Spicer, A. P. (2000) Hyaluronan. A multifunctional, megadalton, stealth molecule. Curr. Opin. Cell Biol. 12, 581-586
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 581-586
    • Lee, J.Y.1    Spicer, A.P.2
  • 21
    • 0035783042 scopus 로고    scopus 로고
    • Hyaluronan in morphogenesis
    • Toole, B. P. (2001) Hyaluronan in morphogenesis. Semin. Cell Dev. Biol. 12, 79-87
    • (2001) Semin. Cell Dev. Biol. , vol.12 , pp. 79-87
    • Toole, B.P.1
  • 22
    • 33645372800 scopus 로고    scopus 로고
    • Hyaluronidases. Their genomics, structures, and mechanisms of action
    • Stern, R., and Jedrzejas, M. J. (2006) Hyaluronidases. Their genomics, structures, and mechanisms of action. Chem. Rev. 106, 818-839
    • (2006) Chem. Rev. , vol.106 , pp. 818-839
    • Stern, R.1    Jedrzejas, M.J.2
  • 24
    • 0037085376 scopus 로고    scopus 로고
    • Hyaluronan-cell interactions in cancer and vascular disease
    • DOI 10.1074/jbc.R100039200
    • Toole, B. P., Wight, T. N., and Tammi, M. I. (2002) Hyaluronan-cell interactions in cancer and vascular disease. J. Biol. Chem. 277, 4593-4596 (Pubitemid 34968485)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.7 , pp. 4593-4596
    • Toole, B.P.1    Wight, T.N.2    Tammi, M.I.3
  • 25
    • 34249703990 scopus 로고    scopus 로고
    • The role of hyaluronic acid in hemopoietic stem cell biology
    • Haylock, D. N., and Nilsson, S. K. (2006) The role of hyaluronic acid in hemopoietic stem cell biology. Regen. Med. 1, 437-445
    • (2006) Regen. Med. , vol.1 , pp. 437-445
    • Haylock, D.N.1    Nilsson, S.K.2
  • 26
    • 79955004401 scopus 로고    scopus 로고
    • Hyaluronan and mesenchymal stem cells. From germ layer to cartilage and bone
    • Astachov, L., Vago, R., Aviv, M., and Nevo, Z. (2011) Hyaluronan and mesenchymal stem cells. From germ layer to cartilage and bone. Front. Biosci. 16, 261-276
    • (2011) Front. Biosci. , vol.16 , pp. 261-276
    • Astachov, L.1    Vago, R.2    Aviv, M.3    Nevo, Z.4
  • 27
    • 0026446637 scopus 로고
    • CD44. The hyaluronan receptor
    • Underhill, C. (1992) CD44. The hyaluronan receptor. J. Cell Sci. 103, 293-298
    • (1992) J. Cell Sci. , vol.103 , pp. 293-298
    • Underhill, C.1
  • 28
    • 44749091776 scopus 로고    scopus 로고
    • Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression
    • Bourguignon, L. Y. (2008) Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression. Semin. Cancer Biol. 18, 251-259
    • (2008) Semin. Cancer Biol. , vol.18 , pp. 251-259
    • Bourguignon, L.Y.1
  • 30
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • DOI 10.1016/S0092-8674(03)00392-1
    • Chambers, I., Colby, D., Robertson, M., Nichols, J., Lee, S., Tweedie, S., and Smith, A. (2003) Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113, 643-655 (Pubitemid 36694189)
    • (2003) Cell , vol.113 , Issue.5 , pp. 643-655
    • Chambers, I.1    Colby, D.2    Robertson, M.3    Nichols, J.4    Lee, S.5    Tweedie, S.6    Smith, A.7
  • 31
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • DOI 10.1016/S0092-8674(03)00393-3
    • Mitsui, K., Tokuzawa, Y., Itoh, H., Segawa, K., Murakami, M., Takahashi, K., Maruyama, M., Maeda, M., and Yamanaka, S. (2003) The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113, 631-642 (Pubitemid 36694188)
    • (2003) Cell , vol.113 , Issue.5 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3    Segawa, K.4    Murakami, M.5    Takahashi, K.6    Maruyama, M.7    Maeda, M.8    Yamanaka, S.9
  • 32
    • 14844359620 scopus 로고    scopus 로고
    • Octamer and sox elements are required for transcriptional cis regulation of Nanog gene expression
    • DOI 10.1128/MCB.25.6.2475-2485.2005
    • Kuroda, T., Tada, M., Kubota, H., Kimura, H., Hatano, S. Y., Suemori, H., Nakatsuji, N., and Tada, T. (2005) Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression. Mol. Cell. Biol. 25, 2475-2485 (Pubitemid 40354640)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.6 , pp. 2475-2485
    • Kuroda, T.1    Tada, M.2    Kubota, H.3    Kimura, H.4    Hatano, S.-Y.5    Suemori, H.6    Nakatsuji, N.7    Tada, T.8
  • 34
    • 34147176234 scopus 로고    scopus 로고
    • Cell-cell fusion as a means to establish pluripotency
    • Do, J. T., and Schöler, H. R. (2006) Cell-cell fusion as a means to establish pluripotency. Ernst Schering Res. Found. Workshop 60, 35-45
    • (2006) Ernst Schering Res. Found. Workshop , vol.60 , pp. 35-45
    • Do, J.T.1    Schöler, H.R.2
  • 35
    • 47749116454 scopus 로고    scopus 로고
    • Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells
    • Bourguignon, L. Y., Peyrollier, K., Xia, W., and Gilad, E. (2008) Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells. J. Biol. Chem. 283, 17635-17651
    • (2008) J. Biol. Chem. , vol.283 , pp. 17635-17651
    • Bourguignon, L.Y.1    Peyrollier, K.2    Xia, W.3    Gilad, E.4
  • 36
    • 70350362953 scopus 로고    scopus 로고
    • Hyaluronan-CD44 interaction with protein kinase C(ε) promotes oncogenic signaling by the stem cell marker Nanog and the production of microRNA-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemotherapy resistance in breast tumor cells
    • Bourguignon, L. Y., Spevak, C. C., Wong, G., Xia, W., and Gilad, E. (2009) Hyaluronan-CD44 interaction with protein kinase C(ε) promotes oncogenic signaling by the stem cell marker Nanog and the production of microRNA-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemotherapy resistance in breast tumor cells. J. Biol. Chem. 284, 26533-26546
    • (2009) J. Biol. Chem. , vol.284 , pp. 26533-26546
    • Bourguignon, L.Y.1    Spevak, C.C.2    Wong, G.3    Xia, W.4    Gilad, E.5
  • 37
    • 33646872074 scopus 로고    scopus 로고
    • NANOGP8 is a retrogene expressed in cancers
    • DOI 10.1002/qua.20952
    • Zhang, J., Wang, X., Li, M., Han, J., Chen, B., Wang, B., and Dai, J. (2006) NANOGP8 is a retrogene expressed in cancers. FEBS J. 273, 1723-1730 (Pubitemid 43779825)
    • (2006) FEBS Journal , vol.273 , Issue.8 , pp. 1723-1730
    • Zhang, J.1    Wang, X.2    Li, M.3    Han, J.4    Chen, B.5    Wang, B.6    Dai, J.7
  • 38
    • 0034175998 scopus 로고    scopus 로고
    • Pairing SOX off: With partners in the regulation of embryonic development
    • DOI 10.1016/S0168-9525(99)01955-1, PII S0168952599019551
    • Kamachi, Y., Uchikawa, M., and Kondoh, H. (2000) Pairing SOX off. With partners in the regulation of embryonic development. Trends Genet. 16, 182-187 (Pubitemid 30169154)
    • (2000) Trends in Genetics , vol.16 , Issue.4 , pp. 182-187
    • Kamachi, Y.1    Uchikawa, M.2    Kondoh, H.3
  • 39
    • 0037227099 scopus 로고    scopus 로고
    • Multipotent cell lineages in early mouse development depend on SOX2 function
    • DOI 10.1101/gad.224503
    • Avilion, A. A., Nicolis, S. K., Pevny, L. H., Perez, L., Vivian, N., and Lovell-Badge, R. (2003) Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev. 17, 126-140 (Pubitemid 36062514)
    • (2003) Genes and Development , vol.17 , Issue.1 , pp. 126-140
    • Avilion, A.A.1    Nicolis, S.K.2    Pevny, L.H.3    Perez, L.4    Vivian, N.5    Lovell-Badge, R.6
  • 40
    • 42649142250 scopus 로고    scopus 로고
    • Sox2 is important for two crucial processes in lung development. Branching morphogenesis and epithelial cell differentiation
    • Gontan, C., de Munck, A., Vermeij, M., Grosveld, F., Tibboel, D., and Rottier, R. (2008) Sox2 is important for two crucial processes in lung development. Branching morphogenesis and epithelial cell differentiation. Dev. Biol. 317, 296-309
    • (2008) Dev. Biol. , vol.317 , pp. 296-309
    • Gontan, C.1    De Munck, A.2    Vermeij, M.3    Grosveld, F.4    Tibboel, D.5    Rottier, R.6
  • 42
    • 0034895829 scopus 로고    scopus 로고
    • Oct-4: Gatekeeper in the beginnings of mammalian development
    • Pesce, M., and Schöler, H. R. (2001) Oct-4. Gatekeeper in the beginnings of mammalian development. Stem Cells 19, 271-278 (Pubitemid 32721093)
    • (2001) Stem Cells , vol.19 , Issue.4 , pp. 271-278
    • Pesce, M.1    Scholer, H.R.2
  • 43
    • 0032582513 scopus 로고    scopus 로고
    • Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
    • DOI 10.1016/S0092-8674(00)81769-9
    • Nichols, J., Zevnik, B., Anastassiadis, K., Niwa, H., Klewe-Nebenius, D., Chambers, I., Schöler, H., and Smith, A. (1998) Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95, 379-391 (Pubitemid 28507326)
    • (1998) Cell , vol.95 , Issue.3 , pp. 379-391
    • Nichols, J.1    Zevnik, B.2    Anastassiadis, K.3    Niwa, H.4    Klewe-Nebenius, D.5    Chambers, I.6    Scholer, H.7    Smith, A.8
  • 44
    • 77953566957 scopus 로고    scopus 로고
    • Concise review. Isoforms of OCT4 contribute to the confusing diversity in stem cell biology
    • Wang, X., and Dai, J. (2010) Concise review. Isoforms of OCT4 contribute to the confusing diversity in stem cell biology. Stem Cells 28, 885- 893
    • (2010) Stem Cells , vol.28 , pp. 885-893
    • Wang, X.1    Dai, J.2
  • 45
    • 67650810301 scopus 로고    scopus 로고
    • Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs
    • Kashyap, V., Rezende, N. C., Scotland, K. B., Shaffer, S. M., Persson, J. L., Gudas, L. J., and Mongan, N. P. (2009) Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs. Stem Cells Dev. 18, 1093-1108
    • (2009) Stem Cells Dev. , vol.18 , pp. 1093-1108
    • Kashyap, V.1    Rezende, N.C.2    Scotland, K.B.3    Shaffer, S.M.4    Persson, J.L.5    Gudas, L.J.6    Mongan, N.P.7
  • 48
    • 0042442335 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs
    • DOI 10.1016/S1534-5807(03)00227-2, PII S1534580703002272
    • Houbaviy, H. B., Murray, M. F., and Sharp, P. A. (2003) Embryonic stem cell-specific microRNAs. Dev. Cell 5, 351-358 (Pubitemid 37006477)
    • (2003) Developmental Cell , vol.5 , Issue.2 , pp. 351-358
    • Houbaviy, H.B.1    Murray, M.F.2    Sharp, P.A.3
  • 51
    • 79951578160 scopus 로고    scopus 로고
    • Oct4 regulates the miR-302 cluster in P19 mouse embryonic carcinoma cells
    • Liu, H., Deng, S., Zhao, Z., Zhang, H., Xiao, J., Song, W., Gao, F., and Guan, Y. (2011) Oct4 regulates the miR-302 cluster in P19 mouse embryonic carcinoma cells. Mol. Biol. Rep. 38, 2155-2160
    • (2011) Mol. Biol. Rep. , vol.38 , pp. 2155-2160
    • Liu, H.1    Deng, S.2    Zhao, Z.3    Zhang, H.4    Xiao, J.5    Song, W.6    Gao, F.7    Guan, Y.8
  • 52
    • 52949125268 scopus 로고    scopus 로고
    • Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state
    • Lin, S. L., Chang, D. C., Chang-Lin, S., Lin, C. H., Wu, D. T., Chen, D. T., and Ying, S. Y. (2008) Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state. RNA 14, 2115-2124
    • (2008) RNA , vol.14 , pp. 2115-2124
    • Lin, S.L.1    Chang, D.C.2    Chang-Lin, S.3    Lin, C.H.4    Wu, D.T.5    Chen, D.T.6    Ying, S.Y.7
  • 54
    • 77954901231 scopus 로고    scopus 로고
    • Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase
    • Clay, M. R., Tabor, M., Owen, J. H., Carey, T. E., Bradford, C. R., Wolf, G. T., Wicha, M. S., and Prince, M. E. (2010) Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase. Head Neck 32, 1195-1201
    • (2010) Head Neck , vol.32 , pp. 1195-1201
    • Clay, M.R.1    Tabor, M.2    Owen, J.H.3    Carey, T.E.4    Bradford, C.R.5    Wolf, G.T.6    Wicha, M.S.7    Prince, M.E.8
  • 55
    • 78650196632 scopus 로고    scopus 로고
    • Regulation of somatic cell reprogramming through inducible mir-302 expression
    • Lin, S. L., Chang, D. C., Lin, C. H., Ying, S. Y., Leu, D., and Wu, D. T. (2011) Regulation of somatic cell reprogramming through inducible mir-302 expression. Nucleic Acids Res. 39, 1054-1065
    • (2011) Nucleic Acids Res. , vol.39 , pp. 1054-1065
    • Lin, S.L.1    Chang, D.C.2    Lin, C.H.3    Ying, S.Y.4    Leu, D.5    Wu, D.T.6
  • 56
    • 0029983762 scopus 로고    scopus 로고
    • Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell
    • DOI 10.1006/dbio.1996.0090
    • Reynolds, B. A., and Weiss, S. (1996) Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonicCNSprecursor is a stem cell. Dev. Biol. 175, 1-13 (Pubitemid 26150042)
    • (1996) Developmental Biology , vol.175 , Issue.1 , pp. 1-13
    • Reynolds, B.A.1    Weiss, S.2
  • 57
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • DOI 10.1101/gad.1061803
    • Dontu, G., Abdallah, W. M., Foley, J. M., Jackson, K. W., Clarke, M. F., Kawamura, M. J., and Wicha, M. S. (2003) In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev. 17, 1253-1270 (Pubitemid 36583168)
    • (2003) Genes and Development , vol.17 , Issue.10 , pp. 1253-1270
    • Dontu, G.1    Abdallah, W.M.2    Foley, J.M.3    Jackson, K.W.4    Clarke, M.F.5    Kawamura, M.J.6    Wicha, M.S.7
  • 58
    • 36249006969 scopus 로고    scopus 로고
    • Self-renewal and multilineage differentiation in vitro from murine prostate stem cells
    • DOI 10.1634/stemcells.2007-0355
    • Xin, L., Lukacs, R. U., Lawson, D. A., Cheng, D., and Witte, O. N. (2007) Self-renewal and multilineage differentiation in vitro from murine prostate stem cells. Stem Cells 25, 2760-2769 (Pubitemid 350127860)
    • (2007) Stem Cells , vol.25 , Issue.11 , pp. 2760-2769
    • Xin, L.1    Lukacs, R.U.2    Lawson, D.A.3    Cheng, D.4    Witte, O.N.5
  • 60
    • 36849078711 scopus 로고    scopus 로고
    • let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
    • DOI 10.1016/j.cell.2007.10.054, PII S0092867407014171
    • Yu, F., Yao, H., Zhu, P., Zhang, X., Pan, Q., Gong, C., Huang, Y., Hu, X., Su, F., Lieberman, J., and Song, E. (2007) let-7 regulates self- renewal and tumorigenicity of breast cancer cells. Cell 131, 1109-1123 (Pubitemid 350235025)
    • (2007) Cell , vol.131 , Issue.6 , pp. 1109-1123
    • Yu, F.1    Yao, H.2    Zhu, P.3    Zhang, X.4    Pan, Q.5    Gong, C.6    Huang, Y.7    Hu, X.8    Su, F.9    Lieberman, J.10    Song, E.11
  • 62
    • 0029124988 scopus 로고
    • The POU domain. Versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain
    • Herr, W., and Cleary, M. A (1995) The POU domain. Versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain. Gene Dev. 9, 1679-1693
    • (1995) Gene Dev. , vol.9 , pp. 1679-1693
    • Herr, W.1    Cleary, M.A.2
  • 63
    • 64949085479 scopus 로고    scopus 로고
    • Oct3/4 and Sox2 are significantly associated with an unfavorable clinical outcome in human esophageal squamous cell carcinoma
    • Wang, Q., He, W., Lu, C., Wang, Z., Wang, J., Giercksky, K. E., Nesland, J. M., and Suo, Z. (2009) Oct3/4 and Sox2 are significantly associated with an unfavorable clinical outcome in human esophageal squamous cell carcinoma. Anticancer Res. 29, 1233-1241
    • (2009) Anticancer Res. , vol.29 , pp. 1233-1241
    • Wang, Q.1    He, W.2    Lu, C.3    Wang, Z.4    Wang, J.5    Giercksky, K.E.6    Nesland, J.M.7    Suo, Z.8
  • 64
    • 37349028055 scopus 로고    scopus 로고
    • Putative role of hyaluronan and its related genes, HAS2 and RHAMM, in human early preimplantation embryogenesis and embryonic stem cell characterization
    • DOI 10.1634/stemcells.2007-0296
    • Choudhary, M., Zhang, X., Stojkovic, P., Hyslop, L., Anyfantis, G., Herbert, M., Murdoch, A. P., Stojkovic, M., and Lako, M. (2007) Putative role of hyaluronan and its related genes, HAS2 and RHAMM, in human early preimplantation embryogenesis and embryonic stem cell characterization. Stem Cells 25, 3045-3057 (Pubitemid 350294430)
    • (2007) Stem Cells , vol.25 , Issue.12 , pp. 3045-3057
    • Choudhary, M.1    Zhang, X.2    Stojkovic, P.3    Hyslop, L.4    Anyfantis, G.5    Herbert, M.6    Murdoch, A.P.7    Stojkovic, M.8    Lako, M.9
  • 65
    • 0029153513 scopus 로고
    • Induction of a hyaluronan receptor, CD44, during embryonal carcinoma and embryonic stem cell differentiation
    • Wheatley, S. C., and Isacke, C. M. (1995) Induction of a hyaluronan receptor, CD44, during embryonal carcinoma and embryonic stem cell differentiation. Cell Adhes. Commun. 3, 217-230
    • (1995) Cell Adhes. Commun. , vol.3 , pp. 217-230
    • Wheatley, S.C.1    Isacke, C.M.2
  • 66
    • 36548999250 scopus 로고    scopus 로고
    • MicroRNAs and cancer
    • DOI 10.1111/j.1600-0463.2007.apm-775.xml.x
    • Cowland, J. B., Hother, C., and Grønbaek, K. (2007) MicroRNAs and cancer. APMIS 115, 1090-1106 (Pubitemid 350179476)
    • (2007) APMIS , vol.115 , Issue.10 , pp. 1090-1106
    • Cowland, J.B.1    Hother, C.2    GronbaeK, K.3
  • 67
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs. MicroRNAs with a role in cancer
    • Esquela-Kerscher, A., and Slack, F. J. (2006) Oncomirs. MicroRNAs with a role in cancer. Nat. Rev. Cancer 6, 259-269
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 68
    • 37549010761 scopus 로고    scopus 로고
    • MicroRNA. Implications for cancer
    • Sassen, S., Miska, E. A., and Caldas, C. (2008) MicroRNA. Implications for cancer. Virchows Arch. 452, 1-10
    • (2008) Virchows Arch. , vol.452 , pp. 1-10
    • Sassen, S.1    Miska, E.A.2    Caldas, C.3
  • 69
    • 70349272130 scopus 로고    scopus 로고
    • KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints
    • Ciccone, D. N., Su, H., Hevi, S., Gay, F., Lei, H., Bajko, J., Xu, G., Li, E., and Chen, T. (2009) KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. Nature 461, 415-418
    • (2009) Nature , vol.461 , pp. 415-418
    • Ciccone, D.N.1    Su, H.2    Hevi, S.3    Gay, F.4    Lei, H.5    Bajko, J.6    Xu, G.7    Li, E.8    Chen, T.9
  • 70
    • 58149156264 scopus 로고    scopus 로고
    • The lysine demethylase LSD1 (KDM1) is required for maintenance of globalDNAmethylation
    • Wang, J., Hevi, S., Kurash, J. K., Lei, H., Gay, F., Bajko, J., Su, H., Sun, W., Chang, H., and Xu, G. (2009) The lysine demethylase LSD1 (KDM1) is required for maintenance of globalDNAmethylation. Nat. Genet. 41, 125-129
    • (2009) Nat. Genet. , vol.41 , pp. 125-129
    • Wang, J.1    Hevi, S.2    Kurash, J.K.3    Lei, H.4    Gay, F.5    Bajko, J.6    Su, H.7    Sun, W.8    Chang, H.9    Xu, G.10
  • 71
    • 83555176258 scopus 로고    scopus 로고
    • Interaction of low molecular weight hyaluronan with CD44 and toll-like receptors promotes the actin filament-associated protein 110-actin binding and MyD88-NFκB signaling leading to proinflammatory cytokine/chemokine production and breast tumor invasion
    • Bourguignon, L. Y., Wong, G., Earle, C. A., and Xia, W. (2011) Interaction of low molecular weight hyaluronan with CD44 and toll-like receptors promotes the actin filament-associated protein 110-actin binding and MyD88-NFκB signaling leading to proinflammatory cytokine/chemokine production and breast tumor invasion. Cytoskeleton 68, 671-693
    • (2011) Cytoskeleton , vol.68 , pp. 671-693
    • Bourguignon, L.Y.1    Wong, G.2    Earle, C.A.3    Xia, W.4


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