-
1
-
-
33846637379
-
Triglycerides and the risk of coronary heart disease 10,158 incident cases among 262,525 participants in 29 Western prospective studies
-
Sarwar N, Danesh J, Eiriksdottir G, et al. Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies. Circulation 2007;115:450-8.
-
(2007)
Circulation
, Issue.115
, pp. 450-458
-
-
Sarwar, N.1
Danesh, J.2
Eiriksdottir, G.3
-
2
-
-
34548798025
-
Changes in triglyceride levels and risk for coronary heart disease in young men
-
Tirosh A, Rudich A, Shochat T, et al. Changes in triglyceride levels and risk for coronary heart disease in young men. Ann Intern Med 2007;147: 377-85.
-
(2007)
Ann Intern Med
, vol.147
, pp. 377-385
-
-
Tirosh, A.1
Rudich, A.2
Shochat, T.3
-
3
-
-
77951875017
-
Triglyceride-mediated pathways and coronary disease: Collaborative analysis of 101 studies
-
for the Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration
-
Sarwar N, Sandhu MS, Ricketts SL, et al., for the Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration. Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. Lancet 2010;375:1634-9.
-
(2010)
Lancet
, vol.375
, pp. 1634-1639
-
-
Sarwar, N.1
Sandhu, M.S.2
Ricketts, S.L.3
-
4
-
-
85027956925
-
Triglycerides and cardiovascular disease: A scientific statement from the American Heart Association
-
Miller M, Stone NJ, Ballantyne C, et al. Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association. Circulation 2011;123:2292-333.
-
(2011)
Circulation
, vol.123
, pp. 2292-2333
-
-
Miller, M.1
Stone, N.J.2
Ballantyne, C.3
-
5
-
-
84906937463
-
The polygenic nature of hypertriglyceridaemia: Implications for definition, diagnosis, and management
-
on behalf of the European Atherosclerosis Society Consensus Panel
-
Hegele RA, Ginsberg HN, Chapman MJ, et al., on behalf of the European Atherosclerosis Society Consensus Panel. The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management. Lancet Diabetes Endocrinol 2014;2:655-66.
-
(2014)
Lancet Diabetes Endocrinol
, vol.2
, pp. 655-666
-
-
Hegele, R.A.1
Ginsberg, H.N.2
Chapman, M.J.3
-
6
-
-
0028172762
-
Triglyceride-rich lipoproteins isolated by selectedaffinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque
-
Rapp JH, Lespine A, Hamilton RL, et al. Triglyceride-rich lipoproteins isolated by selectedaffinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque. Arterioscler Thromb 1994;14:1767-74.
-
(1994)
Arterioscler Thromb
, vol.14
, pp. 1767-1774
-
-
Rapp, J.H.1
Lespine, A.2
Hamilton, R.L.3
-
7
-
-
0035098429
-
Abnormalities in apoBcontaining lipoproteins in diabetes and atherosclerosis
-
Tomkin GH, Ownes D. Abnormalities in apoBcontaining lipoproteins in diabetes and atherosclerosis. Diabetes Metab Res Rev 2001;17:27-43.
-
(2001)
Diabetes Metab Res Rev
, vol.17
, pp. 27-43
-
-
Tomkin, G.H.1
Ownes, D.2
-
8
-
-
50449089236
-
Intestinal lipid transport and chylomicron production: Possible links to exacerbated atherogenesis in a rodent model of the metabolic syndrome
-
Vine DF, Glimm DR, Proctor SD. Intestinal lipid transport and chylomicron production: possible links to exacerbated atherogenesis in a rodent model of the metabolic syndrome. Atheroscler Suppl 2008;9:69-76.
-
(2008)
Atheroscler Suppl
, vol.9
, pp. 69-76
-
-
Vine, D.F.1
Glimm, D.R.2
Proctor, S.D.3
-
9
-
-
0034680309
-
VLDL, Apolipoproteins B, CIII, and E, and risk of recurrent coronary events in the Cholesterol and Recurrent Events (CARE) trial
-
Sacks FM, Alaupovic P, Moye LA, et al. VLDL, Apolipoproteins B, CIII, and E, and risk of recurrent coronary events in the Cholesterol and Recurrent Events (CARE) trial. Circulation 2000;102: 1886-92.
-
(2000)
Circulation
, vol.102
, pp. 1886-1892
-
-
Sacks, F.M.1
Alaupovic, P.2
Moye, L.A.3
-
10
-
-
77951490605
-
Apolipoprotein C-II and the metabolic bases for hypertriglyceridemia and the dense low-density lipoprotein phenotype
-
Zheng C, Khoo C, Furtado J, et al. Apolipoprotein C-II and the metabolic bases for hypertriglyceridemia and the dense low-density lipoprotein phenotype. Circulation 2010;121:1722-34.
-
(2010)
Circulation
, vol.121
, pp. 1722-1734
-
-
Zheng, C.1
Khoo, C.2
Furtado, J.3
-
11
-
-
84891461204
-
Apolipoprotein e in VLDL and LDL with apolipoprotein C-III is associated with a lower risk of coronary heart disease
-
Mendivil CO, Rimm EB, Furtado J, et al. Apolipoprotein E in VLDL and LDL with apolipoprotein C-III is associated with a lower risk of coronary heart disease. J Am Heart Assoc 2013; 2:e000130.
-
(2013)
J Am Heart Assoc
, vol.2
, pp. e000130
-
-
Mendivil, C.O.1
Rimm, E.B.2
Furtado, J.3
-
12
-
-
84897076037
-
Proteome of human plasma very low-density lipoprotein and low-density lipoprotein exhibits a link with coagulation and lipid metabolism
-
Dashty M, Motazacker MM, Levels J, et al. Proteome of human plasma very low-density lipoprotein and low-density lipoprotein exhibits a link with coagulation and lipid metabolism. Thromb Haemost 2014;111:518-30.
-
(2014)
Thromb Haemost
, vol.111
, pp. 518-530
-
-
Dashty, M.1
Motazacker, M.M.2
Levels, J.3
-
13
-
-
84890567652
-
Triglyceriderich lipoproteins and cytosolic lipid droplets in enterocytes: Key players in intestinal physiology and metabolic disorders
-
Demignot S, Deilstein F, Morel E. Triglyceriderich lipoproteins and cytosolic lipid droplets in enterocytes: key players in intestinal physiology and metabolic disorders. Biochimie 2014;96:48-55.
-
(2014)
Biochimie
, vol.96
, pp. 48-55
-
-
Demignot, S.1
Deilstein, F.2
Morel, E.3
-
14
-
-
0035914356
-
Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members
-
Cases S, Stone SJ, Zhou P, et al. Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members. J Biol Chem 2001;276:38870-6.
-
(2001)
J Biol Chem
, vol.276
, pp. 38870-38876
-
-
Cases, S.1
Stone, S.J.2
Zhou, P.3
-
15
-
-
84905101303
-
Preprotein convertase cubtilisin kexin type 9 promotes intestinal overproduction of triglyceride-rich apolipoprotein-B lipoproteins through both LDLreceptor dependent and independent mechanisms
-
Rashid S, Tavori H, Brown PE, et al. Preprotein convertase cubtilisin kexin type 9 promotes intestinal overproduction of triglyceride-rich apolipoprotein-B lipoproteins through both LDLreceptor dependent and independent mechanisms. Circulation 2014;130:431-41.
-
(2014)
Circulation
, vol.130
, pp. 431-441
-
-
Rashid, S.1
Tavori, H.2
Brown, P.E.3
-
16
-
-
49649118045
-
Mansbach CM 2nd PKCzmediated phosphorylation controls budding of the pre-chylomicron transport vesicle
-
Siddiqi SA, Mansbach CM 2nd PKCzmediated phosphorylation controls budding of the pre-chylomicron transport vesicle. J Cell Sci 2008; 121:2327-38.
-
(2008)
J Cell Sci
, vol.121
, pp. 2327-2338
-
-
Siddiqi, S.A.1
-
17
-
-
67650519372
-
A dynamic, cytoplasmic triacylglycerol pool in enterocytes revealed by ex vivo and in vivo coherent anti-Stokes Raman scattering imaging
-
Zhu J, Lee B, Buhman KK, et al. A dynamic, cytoplasmic triacylglycerol pool in enterocytes revealed by ex vivo and in vivo coherent anti- Stokes Raman scattering imaging. J Lipid Res 2009;50:1080-9.
-
(2009)
J Lipid Res
, vol.50
, pp. 1080-1089
-
-
Zhu, J.1
Lee, B.2
Buhman, K.K.3
-
18
-
-
81055148267
-
The proteome of cytosolic lipid droplets isolated from differentiated Caco-2/TC7 enterocytes reveals cell-specific characteristics
-
Bouchoux J, Beilstein F, Pauquai T, et al. The proteome of cytosolic lipid droplets isolated from differentiated Caco-2/TC7 enterocytes reveals cell-specific characteristics. Biol Cell 2011;103: 499-517.
-
(2011)
Biol Cell
, vol.103
, pp. 499-517
-
-
Bouchoux, J.1
Beilstein, F.2
Pauquai, T.3
-
19
-
-
84859863750
-
Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance capacity
-
Adiels M, Matikainen N, Westerbacka J, et al. Postprandial accumulation of chylomicrons and chylomicron remnants is determined by the clearance capacity. Atherosclerosis 2012;222: 222-8.
-
(2012)
Atherosclerosis
, vol.222
, pp. 222-228
-
-
Adiels, M.1
Matikainen, N.2
Westerbacka, J.3
-
20
-
-
0037199988
-
Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-containing lipoprotein overproduction
-
Haidari M, Leung N, Mahbub F, et al. Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-containing lipoprotein overproduction. J Biol Chem 2002;277:31646-55.
-
(2002)
J Biol Chem
, vol.277
, pp. 31646-31655
-
-
Haidari, M.1
Leung, N.2
Mahbub, F.3
-
21
-
-
73149108842
-
Expression of apolipoprotein C-II in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditions
-
Sundaram M, Zhong S, Bou Khalil M, et al. Expression of apolipoprotein C-II in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditions. J Lipid Res 2010;51: 150-61.
-
(2010)
J Lipid Res
, vol.51
, pp. 150-161
-
-
Sundaram, M.1
Zhong, S.2
Bou Khalil, M.3
-
22
-
-
0346220266
-
Apolipoprotein B100 exit from the endoplasmic reticulum (ER) is COPII-dependent, and its lipidation to very low density lipoprotein occurs post-ER
-
Gusarova V, Brodsky JL, Fisher EA. Apolipoprotein B100 exit from the endoplasmic reticulum (ER) is COPII-dependent, and its lipidation to very low density lipoprotein occurs post-ER. J Biol Chem 2003;278:48051-8.
-
(2003)
J Biol Chem
, vol.278
, pp. 48051-48058
-
-
Gusarova, V.1
Brodsky, J.L.2
Fisher, E.A.3
-
23
-
-
58749098423
-
Cideb, an ER- and lipid droplet-associated protein, mediates VLDL lipidation and maturation by interacting with apolipoprotein B
-
Ye J, Li JZ, Liu Y, et al. Cideb, an ER- and lipid droplet-associated protein, mediates VLDL lipidation and maturation by interacting with apolipoprotein B. Cell Metab 2009;9:177-90.
-
(2009)
Cell Metab
, vol.9
, pp. 177-190
-
-
Ye, J.1
Li, J.Z.2
Liu, Y.3
-
24
-
-
0036317550
-
The lipase gene family
-
Wong H, Schotz MC. The lipase gene family. J Lipid Res 2002;43:993-9.
-
(2002)
J Lipid Res
, vol.43
, pp. 993-999
-
-
Wong, H.1
Schotz, M.C.2
-
25
-
-
13944253941
-
Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL
-
Berbée JF, van der Hoogt CC, Sundararaman D, Havekes LM, Rensen PC. Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL. J Lipid Res 2005;46:297-306.
-
(2005)
J Lipid Res
, vol.46
, pp. 297-306
-
-
Berbée, J.F.1
Van Der Hoogt, C.C.2
Sundararaman, D.3
Havekes, L.M.4
Rensen, P.C.5
-
26
-
-
84888335913
-
Apolipoproteins C-I and C-III inhibit lipoprotein lipase activity by displacement of the enzyme from lipid droplets
-
Larsson M, Vorrsjö E, Talmud P, et al. Apolipoproteins C-I and C-III inhibit lipoprotein lipase activity by displacement of the enzyme from lipid droplets. J Biol Chem 2013;288: 33997-4008.
-
(2013)
J Biol Chem
, vol.288
, pp. 33997-34008
-
-
Larsson, M.1
Vorrsjö, E.2
Talmud, P.3
-
27
-
-
4043102703
-
Activation of lipoprotein lipase by native and synthetic fragments of human plasma apolipoprotein C-II
-
Kinnunen PK, Jackson RL, Smith LC, et al. Activation of lipoprotein lipase by native and synthetic fragments of human plasma apolipoprotein C-II. Proc Natl Acad Sci U S A 1977;74: 4848-51.
-
(1977)
Proc Natl Acad Sci U S A
, vol.74
, pp. 4848-4851
-
-
Kinnunen, P.K.1
Jackson, R.L.2
Smith, L.C.3
-
28
-
-
0022971151
-
Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI. Evidence that apo-lipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo
-
Ginsberg HN, Le NA, Goldberg IJ, et al. Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI. Evidence that apo-lipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo. J Clin Invest 1986;78:1287-95.
-
(1986)
J Clin Invest
, vol.78
, pp. 1287-1295
-
-
Ginsberg, H.N.1
Le Goldberg, N.A.I.J.2
-
29
-
-
33644794350
-
Apolipoprotein A-V deficiency results in marked hypertriglyceridemia attributable to decreased lipolysis of triglyceride-rich lipoproteins and removal of their remnants
-
Grosskopf I, Baroukh N, Lee SJ, et al. Apolipoprotein A-V deficiency results in marked hypertriglyceridemia attributable to decreased lipolysis of triglyceride-rich lipoproteins and removal of their remnants. Arterioscler Thromb Vasc Biol 2005;25:2573-9.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 2573-2579
-
-
Grosskopf, I.1
Baroukh, N.2
Lee, S.J.3
-
30
-
-
0037072759
-
ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase
-
Shimizugawa T, Ono M, Shimamura M, et al. ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase. J Biol Chem 2002;277:33742-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 33742-33748
-
-
Shimizugawa, T.1
Ono, M.2
Shimamura, M.3
-
31
-
-
26844540456
-
Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: Regulation of triglyceride metabolism
-
Koster A, Chao YB, Mosior M, et al. Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism. Endocrinology 2005;146:4943-50.
-
(2005)
Endocrinology
, vol.146
, pp. 4943-4950
-
-
Koster, A.1
Chao, Y.B.2
Mosior, M.3
-
32
-
-
33751213896
-
Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue
-
Sukonina V, Lookene A, Olivecrona T, et al. Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue. Proc Natl Acad Sci U S A 2006;103:17450-5.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 17450-17455
-
-
Sukonina, V.1
Lookene, A.2
Olivecrona, T.3
-
33
-
-
84870313030
-
Atypical angiopoietin-like protein that regulates ANGPTL3
-
Quagliarini F, Wang Y, Kozlitina J, et al. Atypical angiopoietin-like protein that regulates ANGPTL3. Proc Natl Acad Sci U S A 2012;109: 19751-6.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 19751-19756
-
-
Quagliarini, F.1
Wang, Y.2
Kozlitina, J.3
-
34
-
-
0034666157
-
Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene
-
Kersten S, Mandard S, Tan NS, et al. Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene. J Biol Chem 2000;275: 28488-93.
-
(2000)
J Biol Chem
, vol.275
, pp. 28488-28493
-
-
Kersten, S.1
Mandard, S.2
Tan, N.S.3
-
35
-
-
77956234052
-
Angiopoietinlike protein 3 inhibits lipoprotein lipase activity through enhancing its cleavage by proprotein convertases
-
Liu J, Afroza H, Rader DJ, et al. Angiopoietinlike protein 3 inhibits lipoprotein lipase activity through enhancing its cleavage by proprotein convertases. J Biol Chem 2010;285:27561-70.
-
(2010)
J Biol Chem
, vol.285
, pp. 27561-27570
-
-
Liu, J.1
Afroza, H.2
Rader, D.J.3
-
36
-
-
33646689532
-
Lipoprotein lipase bound to apolipoprotein B lipoproteins accelerates clearance of postprandial lipoproteins in humans
-
Zheng C, Murdoch SJ, Brunzell JD, et al. Lipoprotein lipase bound to apolipoprotein B lipoproteins accelerates clearance of postprandial lipoproteins in humans. Arterioscler Thromb Vasc Biol 2006;26:891-6.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 891-896
-
-
Zheng, C.1
Murdoch, S.J.2
Brunzell, J.D.3
-
37
-
-
0028136770
-
Mouse very-low density-lipoprotein receptor (VLDLR) cDNA cloning, tissue-specific expression and evolutionary relationship with the low-density lipoprotein receptor
-
Oka K, Ishimura-Oka K, Chu MJ, et al. Mouse very-low density-lipoprotein receptor (VLDLR) cDNA cloning, tissue-specific expression and evolutionary relationship with the low-density lipoprotein receptor. Eur J Biochem 1994;224: 975-82.
-
(1994)
Eur J Biochem
, vol.224
, pp. 975-982
-
-
Oka, K.1
Ishimura-Oka, K.2
Chu, M.J.3
-
38
-
-
0028324441
-
Characterization and tissue-specific expression of the human "very low density lipoprotein (VLDL) receptor"
-
Webb JC, Patel DD, Jones MD, et al. Characterization and tissue-specific expression of the human "very low density lipoprotein (VLDL) receptor" mRNA. Hum Mol Genet 1994;3:531-7.
-
(1994)
MRNA. Hum Mol Genet
, vol.3
, pp. 531-537
-
-
Webb, J.C.1
Patel, D.D.2
Jones, M.D.3
-
39
-
-
0029896320
-
Expression of very low density lipoprotein receptor in the vascular wall. Analysis of human tissues by in situ hybridization and immunohistochemistry
-
Multhaupt HA, Gafvels ME, Kariko K, et al. Expression of very low density lipoprotein receptor in the vascular wall. Analysis of human tissues by in situ hybridization and immunohistochemistry. Am J Pathol 1996;148:1985-97.
-
(1996)
Am J Pathol
, vol.148
, pp. 1985-1997
-
-
Multhaupt, H.A.1
Gafvels, M.E.2
Kariko, K.3
-
40
-
-
84905002314
-
Upregulation of hepatic VLDLR via PPARa is required for the triglyceride-lowering effect of fenofibrate
-
Gao Y, Shen W, Zhang Q, et al. Upregulation of hepatic VLDLR via PPARa is required for the triglyceride-lowering effect of fenofibrate. J Lipid Res 2014;55:1622-33.
-
(2014)
J Lipid Res
, vol.55
, pp. 1622-1633
-
-
Gao, Y.1
Shen, W.2
Zhang, Q.3
-
41
-
-
0033889707
-
ApoE in atherosclerosis: A protein with multiple hats
-
Curtiss LK. ApoE in atherosclerosis: a protein with multiple hats. Arterioscler Thromb Vasc Biol 2000;20:1852-3.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 1852-1853
-
-
Curtiss, L.K.1
-
42
-
-
79955062470
-
Endothelial inflammation correlates with subject triglycerides and waist size after a high-fat meal
-
Wang YI, Schultze J, Raymond N, et al. Endothelial inflammation correlates with subject triglycerides and waist size after a high-fat meal. AJP Heart Circ Physiol 2011;300:H784-91.
-
(2011)
AJP Heart Circ Physiol
, vol.300
, pp. H784-H791
-
-
Wang, Y.I.1
Schultze, J.2
Raymond, N.3
-
43
-
-
84867026573
-
IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high fat meal
-
Sun C, Alkhoury K, Wang YI, et al. IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high fat meal. Circ Res 2012;111: 1054-64.
-
(2012)
Circ Res
, vol.111
, pp. 1054-1064
-
-
Sun, C.1
Alkhoury, K.2
Wang, Y.I.3
-
44
-
-
78650908286
-
CD11c/ CD18 expression is upregulated on blood monocytes during hypertriglyceridemia and enhances adhesion to vascular cell adhesion molecule-1
-
Gower RM, Wu H, Foster GA, et al. CD11c/ CD18 expression is upregulated on blood monocytes during hypertriglyceridemia and enhances adhesion to vascular cell adhesion molecule-1. Arterioscler Thromb Vasc Biol 2011;31:160-6.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 160-166
-
-
Gower, R.M.1
Wu, H.2
Foster, G.A.3
-
45
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004;306:457-61.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
-
46
-
-
70149098183
-
Chronic endoplasmic reticulum stress activates unfolded protein response in arterial endothelium in regions of susceptibility to atherosclerosis
-
Civelek M, Manduchi E, Riley RJ, et al. Chronic endoplasmic reticulum stress activates unfolded protein response in arterial endothelium in regions of susceptibility to atherosclerosis. Circ Res 2009; 105:453-61.
-
(2009)
Circ Res
, vol.105
, pp. 453-461
-
-
Civelek, M.1
Manduchi, E.2
Riley, R.J.3
-
47
-
-
84886916904
-
Triglyceriderich lipoprotein modulates endothelial vascular cell adhesion molecule (VCAM)-1 expression via differential regulation of endoplasmic reticulum stress
-
Wang YI, Bettaieb A, Sun C, et al. Triglyceriderich lipoprotein modulates endothelial vascular cell adhesion molecule (VCAM)-1 expression via differential regulation of endoplasmic reticulum stress. PLoS One 2013;8:e78322.
-
(2013)
PLoS One
, vol.8
, pp. e78322
-
-
Wang, Y.I.1
Bettaieb, A.2
Sun, C.3
-
48
-
-
64749100482
-
Triglyceride- rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation
-
Wang L, Gill R, Pedersen TL, et al. Triglyceride- rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation. J Lipid Res 2009;50:204-13.
-
(2009)
J Lipid Res
, vol.50
, pp. 204-213
-
-
Wang, L.1
Gill, R.2
Pedersen, T.L.3
-
49
-
-
49849085120
-
Triglyceride-rich lipoprotein lipolysis increases aggregation of endothelial cell membrane microdomains and produces reactive oxygen species
-
Wang L, Sapuri-Butti AR, Aung HH, et al. Triglyceride-rich lipoprotein lipolysis increases aggregation of endothelial cell membrane microdomains and produces reactive oxygen species. Am J Physiol Heart Circ Physiol 2008;295: H237-44.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
, pp. H237-H244
-
-
Wang, L.1
Sapuri-Butti, A.R.2
Aung, H.H.3
-
50
-
-
84883304683
-
Induction of ATF3 gene network by triglyceride-rich lipoprotein lipolysis products increases vascular apoptosis and inflammation
-
Aung HH, Lane MW, Gohil K, et al. Induction of ATF3 gene network by triglyceride-rich lipoprotein lipolysis products increases vascular apoptosis and inflammation. Arterioscler Thromb Vasc Biol 2013; 33:2088-96.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 2088-2096
-
-
Aung, H.H.1
Lane, M.W.2
Gohil, K.3
-
51
-
-
0034646737
-
Direct visualization of lipid deposition and reverse lipid transport in a perfused artery: Roles of VLDL and HDL
-
Rutledge JC, Mullick AE, Gardner G, et al. Direct visualization of lipid deposition and reverse lipid transport in a perfused artery: roles of VLDL and HDL. Circ Res 2000;86:768-73.
-
(2000)
Circ Res
, vol.86
, pp. 768-773
-
-
Rutledge, J.C.1
Mullick, A.E.2
Gardner, G.3
-
52
-
-
78650514130
-
Complex links between dietary lipids, endogenous endotoxins and metabolic inflammation
-
Laugerette F, Vors C, Peretti N, et al. Complex links between dietary lipids, endogenous endotoxins and metabolic inflammation. Biochimie 2011;93:39-45.
-
(2011)
Biochimie
, vol.93
, pp. 39-45
-
-
Laugerette, F.1
Vors, C.2
Peretti, N.3
-
53
-
-
84866146620
-
Evaluation and treatment of hypertriglyceridemia: An Endocrine Society clinical practice guideline
-
for the Endocrine Society
-
Berglund L, Brunzell JD, Goldberg AC, et al., for the Endocrine Society. Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2012;97:2969-89.
-
(2012)
J Clin Endocrinol Metab
, vol.97
, pp. 2969-2989
-
-
Berglund, L.1
Brunzell, J.D.2
Goldberg, A.C.3
-
54
-
-
79958148945
-
Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: Evidence and guidance for management
-
for the European Atherosclerosis Society Consensus Panel
-
Chapman MJ, Ginsberg HN, Amarenco P, et al., for the European Atherosclerosis Society Consensus Panel. Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. Eur Heart J 2011;32: 1345-61.
-
(2011)
Eur Heart J
, vol.32
, pp. 1345-1361
-
-
Chapman, M.J.1
Ginsberg, H.N.2
Amarenco, P.3
-
55
-
-
0036795589
-
Cholesteryl ester flux from HDL to VLDL-1 is preferentially enhanced in type IIB hyperlipidemia in the postprandial state
-
Guerin M, Egger P, Soudant C, et al. Cholesteryl ester flux from HDL to VLDL-1 is preferentially enhanced in type IIB hyperlipidemia in the postprandial state. J Lipid Res 2002;43:1652-60.
-
(2002)
J Lipid Res
, vol.43
, pp. 1652-1660
-
-
Guerin, M.1
Egger, P.2
Soudant, C.3
-
56
-
-
79958236842
-
Heterogenous postprandial lipoprotein responses in the metabolic syndrome, and response to fenofibrate therapy
-
Rosenson RS, Helenowski IB, Tangney CC. Heterogenous postprandial lipoprotein responses in the metabolic syndrome, and response to fenofibrate therapy. Cardiovasc Drugs Ther 2010; 24:439-47.
-
(2010)
Cardiovasc Drugs Ther
, vol.24
, pp. 439-447
-
-
Rosenson, R.S.1
Helenowski, I.B.2
Tangney, C.C.3
-
57
-
-
0017089461
-
Chylomicron clearance in normal and hyperlipidemic man
-
Grundy SM, Mok HY. Chylomicron clearance in normal and hyperlipidemic man. Metabolism 1976; 25:1225-39.
-
(1976)
Metabolism
, vol.25
, pp. 1225-1239
-
-
Grundy, S.M.1
Mok, H.Y.2
-
58
-
-
0031964114
-
Preferential cholesteryl ester acceptors among triglyceride-rich lipoproteins during alimentary lipemia in normolipidemic subjects
-
Lassel TS, Guerin M, Auboiron S, et al. Preferential cholesteryl ester acceptors among triglyceride-rich lipoproteins during alimentary lipemia in normolipidemic subjects. Arterioscler Thromb Vasc Biol 1998;18:65-74.
-
(1998)
Arterioscler Thromb Vasc Biol
, vol.18
, pp. 65-74
-
-
Lassel, T.S.1
Guerin, M.2
Auboiron, S.3
-
59
-
-
0023922609
-
Postprandial plasma lipoprotein changes in human subjects of different ages
-
Cohn JS, McNamara Jr., Cohn SD, et al. Postprandial plasma lipoprotein changes in human subjects of different ages. J Lipid Res 1988;29: 469-79.
-
(1988)
J Lipid Res
, vol.29
, pp. 469-479
-
-
Cohn, J.S.1
McNamara2
Cohn, S.D.3
-
60
-
-
57149133676
-
Fasting and nonfasting lipid levels: Influence of normal food intake on lipids, lipoproteins, apolipoproteins, and cardiovascular risk prediction
-
Langsted A, Freiberg JJ, Nordestgaard BG. Fasting and nonfasting lipid levels: influence of normal food intake on lipids, lipoproteins, apolipoproteins, and cardiovascular risk prediction. Circulation 2008;118:2047-56.
-
(2008)
Circulation
, vol.118
, pp. 2047-2056
-
-
Langsted, A.1
Freiberg, J.J.2
Nordestgaard, B.G.3
-
61
-
-
84864813405
-
Postprandial triglyceride is associated with fasting triglyceride and HOMA-IR in Korean subjects with type 2 diabetes
-
Lee SH, Lee BW, Won HK, et al. Postprandial triglyceride is associated with fasting triglyceride and HOMA-IR in Korean subjects with type 2 diabetes. Diabetes Metab J 2011;35:404-10.
-
(2011)
Diabetes Metab J
, vol.35
, pp. 404-410
-
-
Lee, S.H.1
Lee, B.W.2
Won, H.K.3
-
62
-
-
38749102352
-
Fasting versus nonfasting triglycerides and the prediction of cardiovascular risk: Do we need to revisit the oral triglyceride tolerance test?
-
Ridker PM. Fasting versus nonfasting triglycerides and the prediction of cardiovascular risk: do we need to revisit the oral triglyceride tolerance test? Clin Chem 2008;54:11-3.
-
(2008)
Clin Chem
, vol.54
, pp. 11-13
-
-
Ridker, P.M.1
-
63
-
-
34547687824
-
Fenofibrate therapy ameliorates fasting and postprandial lipoproteinemia, oxidative stress, and the inflammatory response among hypertriglyceridemia subjects with the metabolic syndrome
-
Rosenson RS, Wolff DA, Huskin AL, et al. Fenofibrate therapy ameliorates fasting and postprandial lipoproteinemia, oxidative stress, and the inflammatory response among hypertriglyceridemia subjects with the metabolic syndrome. Diabetes Care 2007;30:1945-51.
-
(2007)
Diabetes Care
, vol.30
, pp. 1945-1951
-
-
Rosenson, R.S.1
Wolff, D.A.2
Huskin, A.L.3
-
64
-
-
34447520136
-
Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women
-
Bansal S, Buring JE, Rifai N, et al. Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA 2007;298: 309-16.
-
(2007)
JAMA
, vol.298
, pp. 309-316
-
-
Bansal, S.1
Buring, J.E.2
Rifai, N.3
-
65
-
-
34447511196
-
Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
-
Nordestgaard BG, Benn M, Schnohr P, et al. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 2007;298:299-308.
-
(2007)
JAMA
, vol.298
, pp. 299-308
-
-
Nordestgaard, B.G.1
Benn, M.2
Schnohr, P.3
-
66
-
-
0029005963
-
Postprandial lipoprotein metabolism and atherosclerosis
-
Karpe F, Hamsten A. Postprandial lipoprotein metabolism and atherosclerosis. Curr Opin Lipidol 1995;6:123-9.
-
(1995)
Curr Opin Lipidol
, vol.6
, pp. 123-129
-
-
Karpe, F.1
Hamsten, A.2
-
68
-
-
77149158128
-
Introduction to the DISRUPT postprandial database: Subjects, studies and methodologies
-
Jackson KG, Clarke DT, Murray P, et al. Introduction to the DISRUPT postprandial database: subjects, studies and methodologies. Genes Nutr 2009;5:39-48.
-
(2009)
Genes Nutr
, vol.5
, pp. 39-48
-
-
Jackson, K.G.1
Clarke, D.T.2
Murray, P.3
-
69
-
-
0018649439
-
Atherogenesis: A postprandial phenomenon
-
Zilversmit DB. Atherogenesis: a postprandial phenomenon. Circulation 1979;60:473-85.
-
(1979)
Circulation
, vol.60
, pp. 473-485
-
-
Zilversmit, D.B.1
-
70
-
-
70450081001
-
Major lipids, apolipoproteins, and risk of vascular disease
-
for the Emerging Risk Factors Collaboration
-
Di Angelantoni E, Sarwar N, Perry P, et al., for the Emerging Risk Factors Collaboration. Major lipids, apolipoproteins, and risk of vascular disease. JAMA 2009;302:1993-2000.
-
(2009)
JAMA
, vol.302
, pp. 1993-2000
-
-
Di Angelantoni, E.1
Sarwar, N.2
Perry, P.3
-
71
-
-
0031743318
-
Retention of chylomicron remnants by arterial tissue: Importance of an efficient clearance mechanism from plasma
-
Mamo JC, Proctor SD, Smith D. Retention of chylomicron remnants by arterial tissue: importance of an efficient clearance mechanism from plasma. Atherosclerosis 1998;141 Suppl 1:S63-9.
-
(1998)
Atherosclerosis
, vol.141
, pp. S63-S69
-
-
Mamo, J.C.1
Proctor, S.D.2
Smith, D.3
-
72
-
-
84872675457
-
Remnant cholesterol as a causal risk factor for ischemic heart disease
-
Varbo A, Benn M, Tybjaerg-Hansen A, et al. Remnant cholesterol as a causal risk factor for ischemic heart disease. J Am Coll Cardiol 2013;61: 427-36.
-
(2013)
J Am Coll Cardiol
, vol.61
, pp. 427-436
-
-
Varbo, A.1
Benn, M.2
Tybjaerg-Hansen, A.3
-
73
-
-
84876175810
-
Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction
-
Jørgensen AB, Frikke-Schmidt R, West AS, et al. Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction. Eur Heart J 2013;34:1826-33.
-
(2013)
Eur Heart J
, vol.34
, pp. 1826-1833
-
-
Jørgensen, A.B.1
Frikke-Schmidt, R.2
West, A.S.3
-
74
-
-
84155163221
-
Postprandial lipemia and cardiovascular disease risk: Interrelationships between dietary, physiological and genetic determinants
-
Jackson KG, Poppitt SD, Minihane AM, et al. Postprandial lipemia and cardiovascular disease risk: Interrelationships between dietary, physiological and genetic determinants. Atherosclerosis 2012;220:22-33.
-
(2012)
Atherosclerosis
, vol.220
, pp. 22-33
-
-
Jackson, K.G.1
Poppitt, S.D.2
Minihane, A.M.3
-
75
-
-
0035812707
-
An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing
-
Pennachio LA, Olivier M, Hubacek JA, et al. An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science 2001;294:169-73.
-
(2001)
Science
, vol.294
, pp. 169-173
-
-
Pennachio, L.A.1
Olivier, M.2
Hubacek, J.A.3
-
76
-
-
17144407867
-
Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study
-
Lai CQ, Demissie S, Cupples LA, et al. Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study. J Lipid Res 2004;45: 2096-105.
-
(2004)
J Lipid Res
, vol.45
, pp. 2096-2105
-
-
Lai, C.Q.1
Demissie, S.2
Cupples, L.A.3
-
77
-
-
33646762457
-
Variants at the ApoA5 locus, association with carotid atherosclerosis, and modification by obesity: The Framingham Study
-
Elosua R, Ordovas JM, Cupples LA, et al. Variants at the ApoA5 locus, association with carotid atherosclerosis, and modification by obesity: the Framingham Study. J Lipid Res 2006;47:990-6.
-
(2006)
J Lipid Res
, vol.47
, pp. 990-996
-
-
Elosua, R.1
Ordovas, J.M.2
Cupples, L.A.3
-
78
-
-
34249294501
-
Fenofibrate effect on triglyceride and postprandial response of apolipoprotein A5 variants: The GOLDN study
-
Lai CQ, Arnett DK, Corella D, et al. Fenofibrate effect on triglyceride and postprandial response of apolipoprotein A5 variants: the GOLDN study. Arterioscler Thromb Vasc Biol 2007;27:1417-25.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 1417-1425
-
-
Lai, C.Q.1
Arnett, D.K.2
Corella, D.3
-
79
-
-
84872682094
-
Remnant cholesterol: "non- (HDL-C + LDL-C)" as a coronary artery disease risk factor
-
McPherson R. Remnant cholesterol: "Non- (HDL-C + LDL-C)" as a coronary artery disease risk factor. J Am Coll Cardiol 2013;61:437-9.
-
(2013)
J Am Coll Cardiol
, vol.61
, pp. 437-439
-
-
McPherson, R.1
-
80
-
-
84859184996
-
Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: A meta-analysis
-
Boekholdt SM, Arsenault BJ, Mora S, et al. Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis. JAMA 2012;307:1302-9.
-
(2012)
JAMA
, vol.307
, pp. 1302-1309
-
-
Boekholdt, S.M.1
Arsenault, B.J.2
Mora, S.3
-
81
-
-
0037126526
-
-
National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report
-
National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002;106:3143-421.
-
(2002)
Circulation
, vol.106
, pp. 3143-3421
-
-
-
82
-
-
84902576469
-
ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
-
Stone NJ, Robinson JG, Lichtenstein AH, et al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2014;63:2889-934.
-
(2013)
J Am Coll Cardiol
, vol.2014
, Issue.63
, pp. 2889-2934
-
-
Stone, N.J.1
Robinson, J.G.2
Lichtenstein, A.H.3
-
83
-
-
58249086417
-
Metaanalysis of the relationship between non-highdensity lipoprotein cholesterol reduction and coronary heart disease risk
-
Robinson JG, Wang S, Smith BJ, et al. Metaanalysis of the relationship between non-highdensity lipoprotein cholesterol reduction and coronary heart disease risk. J Am Coll Cardiol 2009;53:316-22.
-
(2009)
J Am Coll Cardiol
, vol.53
, pp. 316-322
-
-
Robinson, J.G.1
Wang, S.2
Smith, B.J.3
-
84
-
-
70549114061
-
Management of non-highdensity lipoprotein abnormalities
-
Rosenson RS. Management of non-highdensity lipoprotein abnormalities. Atherosclerosis 2009;207:328-35.
-
(2009)
Atherosclerosis
, vol.207
, pp. 328-335
-
-
Rosenson, R.S.1
-
85
-
-
84899656061
-
Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study
-
Hoogeveen RC, Gaubatz JW, Sun W, et al. Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study. Arterioscler Thromb Vasc Biol 2014; 34:1069-77.
-
(2014)
Arterioscler Thromb Vasc Biol
, vol.34
, pp. 1069-1077
-
-
Hoogeveen, R.C.1
Gaubatz, J.W.2
Sun, W.3
-
86
-
-
61849110301
-
Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipid and apolipoproteins in predicting incident cardiovascular disease in women
-
Mora S, Otvos JD, Rifai N, et al. Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipid and apolipoproteins in predicting incident cardiovascular disease in women. Circulation 2009;119:931-9.
-
(2009)
Circulation
, vol.119
, pp. 931-939
-
-
Mora, S.1
Otvos, J.D.2
Rifai, N.3
-
87
-
-
77958485863
-
Underappreciated opportunities for low-density lipoprotein management in patients with cardiometabolic residual risk
-
Rosenson RS, Davidson MH, Pourfarzib R. Underappreciated opportunities for low-density lipoprotein management in patients with cardiometabolic residual risk. Atherosclerosis 2010;213:1-7.
-
(2010)
Atherosclerosis
, vol.213
, pp. 1-7
-
-
Rosenson, R.S.1
Davidson, M.H.2
Pourfarzib, R.3
-
88
-
-
41549118416
-
Lipoprotein management in patients with cardiometabolic risk: Consensus conference report from the American Diabetes Association and the American College of Cardiology Foundation
-
Brunzell JD, Davidson M, Furberg CD, et al. Lipoprotein management in patients with cardiometabolic risk: consensus conference report from the American Diabetes Association and the American College of Cardiology Foundation. J Am Coll Cardiol 2008;51:1512-24.
-
(2008)
J Am Coll Cardiol
, vol.51
, pp. 1512-1524
-
-
Brunzell, J.D.1
Davidson, M.2
Furberg, C.D.3
-
89
-
-
62149099979
-
Apolipoprotein B and cardiovascular disease risk: Position statement from the AACC Lipoproteins and Vascular Diseases Division Working Group on Best Practices
-
Contois JH, McConnell JP, Sethi AA, et al. Apolipoprotein B and cardiovascular disease risk: position statement from the AACC Lipoproteins and Vascular Diseases Division Working Group on Best Practices. Clin Chem 2009;55:407-19.
-
(2009)
Clin Chem
, vol.55
, pp. 407-419
-
-
Contois, J.H.1
McConnell, J.P.2
Sethi, A.A.3
-
90
-
-
80053914425
-
Clinical utility of inflammatorymarkers and advanced lipoprotein testing: Advice from an expert panel of lipid specialists
-
DavidsonMH, Ballantyne CM, Jacobson TA, et al. Clinical utility of inflammatorymarkers and advanced lipoprotein testing: advice from an expert panel of lipid specialists. J Clin Lipidol 2011;5:338-67.
-
(2011)
J Clin Lipidol
, vol.5
, pp. 338-367
-
-
Davidson, M.H.1
Ballantyne, C.M.2
Jacobson, T.A.3
-
91
-
-
84890566037
-
American Association of Clinical Endocrinologists' comprehensive diabetes management algorithm 2013 consensus statement-executive summary
-
Garber AJ, Abrahamson MJ, Barzilay JI, et al. American Association of Clinical Endocrinologists' comprehensive diabetes management algorithm 2013 consensus statement-executive summary. Endocr Pract 2013;19:536-57.
-
(2013)
Endocr Pract
, vol.19
, pp. 536-557
-
-
Garber, A.J.1
Abrahamson, M.J.2
Barzilay, J.I.3
-
92
-
-
79960205374
-
ESC/ EAS guidelines for the management of dyslipidaemias: The Task Force for the Management of Dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)
-
Catapano AL, Reiner Z, De Backer G, et al. ESC/ EAS guidelines for the management of dyslipidaemias: The Task Force for the Management of Dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Atherosclerosis 2011;217:3-46.
-
(2011)
Atherosclerosis
, vol.217
, pp. 3-46
-
-
Catapano, A.L.1
Reiner, Z.2
De Backer, G.3
-
93
-
-
84893935789
-
An International Atherosclerosis Society position paper: Global recommendations for the management of dyslipidemia-full report
-
Expert Dyslipidemia Panel of the International Atherosclerosis Society Panel Members
-
Expert Dyslipidemia Panel of the International Atherosclerosis Society Panel Members. An International Atherosclerosis Society position paper: global recommendations for the management of dyslipidemia- full report. J Clin Lipidol 2014;8:29-60.
-
(2014)
J Clin Lipidol
, vol.8
, pp. 29-60
-
-
-
94
-
-
84892891105
-
An International Atherosclerosis Society position paper: Global recommendations for the management of dyslipidemia: Executive summary
-
Expert Panel on Dyslipidemia
-
Expert Panel on Dyslipidemia. An International Atherosclerosis Society position paper: global recommendations for the management of dyslipidemia: executive summary. Atherosclerosis 2014;232:410-3.
-
(2014)
Atherosclerosis
, vol.232
, pp. 410-413
-
-
-
95
-
-
33645096052
-
Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: Report of the thirty-person/ten-country panel
-
Barter PJ, Ballantyne CM, Carmena R, et al. Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/ten-country panel. J Intern Med 2006;259:247-58.
-
(2006)
J Intern Med
, vol.259
, pp. 247-258
-
-
Barter, P.J.1
Ballantyne, C.M.2
Carmena, R.3
-
96
-
-
53749096800
-
Variation in ANGPTL4 and risk of coronary heart disease: The Atherosclerosis Risk in Communities Study
-
Folsom AR, Peacock JM, Demerath E, Boerwinkle E. Variation in ANGPTL4 and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study. Metabolism 2008;57:1591-6.
-
(2008)
Metabolism
, vol.57
, pp. 1591-1596
-
-
Folsom, A.R.1
Peacock, J.M.2
Demerath, E.3
Boerwinkle, E.4
-
97
-
-
61749090233
-
Rare lossof- function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans
-
Romeo S, Yin W, Kozlitina J, et al. Rare lossof- function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. J Clin Invest 2009;119:70-9.
-
(2009)
J Clin Invest
, vol.119
, pp. 70-79
-
-
Romeo, S.1
Yin, W.2
Kozlitina, J.3
-
98
-
-
78649755576
-
Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia
-
Musunuru K, Pirruccello JP, Do R, et al. Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia. N Engl J Med 2010;363: 2220-7.
-
(2010)
N Engl J Med
, vol.363
, pp. 2220-2227
-
-
Musunuru, K.1
Pirruccello, J.P.2
Do, R.3
-
99
-
-
58149262866
-
A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection
-
Pollin TI, Damcott CM, Shen H, et al. A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection. Science 2008;322:1702-5.
-
(2008)
Science
, vol.322
, pp. 1702-1705
-
-
Pollin, T.I.1
Damcott, C.M.2
Shen, H.3
-
100
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
for the Diabetes Genetics Initiative of Broad Institute of Harvard and MIT Lund University and Novartis Institutes of BioMedical Research
-
Saxena R, Voight BF, Lyssenko V, et al., for the Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007;316: 1331-6.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
-
101
-
-
84893756641
-
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks
-
Peloso GM, Auer PL, Bis JC, et al. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am J Hum Genet 2014;94:223-32.
-
(2014)
Am J Hum Genet
, vol.94
, pp. 223-232
-
-
Peloso, G.M.1
Auer, P.L.2
Bis, J.C.3
-
102
-
-
38649125868
-
Newly identified loci that influence lipid concentrations and risk of coronary artery disease
-
Willer CJ, Sanna S, Jackson AU, et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 2008;40:161-9.
-
(2008)
Nat Genet
, vol.40
, pp. 161-169
-
-
Willer, C.J.1
Sanna, S.2
Jackson, A.U.3
-
103
-
-
38649132270
-
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
-
Kathiresan S, Melander O, Guiducci C, et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet 2008;40:189-97.
-
(2008)
Nat Genet
, vol.40
, pp. 189-197
-
-
Kathiresan, S.1
Melander, O.2
Guiducci, C.3
-
104
-
-
58149163149
-
Common variants at 30 loci contribute to polygenic dyslipidemia
-
Kathiresan S, Willer CJ, Peloso GM, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2009;41:56-65.
-
(2009)
Nat Genet
, vol.41
, pp. 56-65
-
-
Kathiresan, S.1
Willer, C.J.2
Peloso, G.M.3
-
105
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich TM, Musunuru K, Smith AV, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010;466:707-13.
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
Musunuru, K.2
Smith, A.V.3
-
106
-
-
84887099827
-
Discovery and refinement of loci associated with lipid levels
-
for the Global Lipids Genetics Consortium
-
Willer CJ, Schmidt EM, Sengupta S, et al., for the Global Lipids Genetics Consortium. Discovery and refinement of loci associated with lipid levels. Nat Genet 2013;45:1274-83.
-
(2013)
Nat Genet
, vol.45
, pp. 1274-1283
-
-
Willer, C.J.1
Schmidt, E.M.2
Sengupta, S.3
-
108
-
-
77955070766
-
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia
-
Johansen CT, Wang J, Lanktree MB, et al. Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. Nat Genet 2010;42:684-7.
-
(2010)
Nat Genet
, vol.42
, pp. 684-687
-
-
Johansen, C.T.1
Wang, J.2
Lanktree, M.B.3
-
109
-
-
84887058576
-
Common variants associated with plasma triglycerides and risk for coronary artery disease
-
Do R, Willer CJ, Schmidt EM, et al. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013; 45:1345-52.
-
(2013)
Nat Genet
, vol.45
, pp. 1345-1352
-
-
Do, R.1
Willer, C.J.2
Schmidt, E.M.3
-
110
-
-
84903727023
-
Loss-of-function mutations in APOC3, triglycerides, and coronary disease
-
The TG and HDL Working Group of the Exome Sequencing Project, National Heart, Lung, and Blood Institute
-
The TG and HDL Working Group of the Exome Sequencing Project, National Heart, Lung, and Blood Institute. Loss-of-function mutations in APOC3, triglycerides, and coronary disease. N Engl J Med 2014;371:22-3.
-
(2014)
N Engl J Med
, vol.371
, pp. 22-23
-
-
-
111
-
-
84903743893
-
Loss-of-function mutations in APOC3 and risk of ischemic vascular disease
-
Jørgensen AB, Frikke-Schmidt R, Nordestgaard BG, et al. Loss-of-function mutations in APOC3 and risk of ischemic vascular disease. N Engl J Med 2014;371:32-41.
-
(2014)
N Engl J Med
, vol.371
, pp. 32-41
-
-
Jørgensen, A.B.1
Frikke-Schmidt, R.2
Nordestgaard, B.G.3
-
112
-
-
0032567978
-
Comparison of statins in hypertriglyceridemia
-
Stein EA, Lane M, Laskarzewski P. Comparison of statins in hypertriglyceridemia. Am J Cardiol 1998;81:66B-9B.
-
(1998)
Am J Cardiol
, vol.81
, pp. 66B-69B
-
-
Stein, E.A.1
Lane, M.2
Laskarzewski, P.3
-
113
-
-
79151472006
-
Etiology and risk of lactescent plasma and severe hypertriglyceridemia
-
Tremblay K, Méthot J, Brisson D, et al. Etiology and risk of lactescent plasma and severe hypertriglyceridemia. J Clin Lipidol 2011;5:37-44.
-
(2011)
J Clin Lipidol
, vol.5
, pp. 37-44
-
-
Tremblay, K.1
Méthot, J.2
Brisson, D.3
-
114
-
-
2442711384
-
Peroxisome proliferator-activated receptors and atherogenesis: Regulators of gene expression in vascular cells
-
Marx N, Duez H, Fruchart JC, et al. Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells. Circ Res 2004;94:1168-78.
-
(2004)
Circ Res
, vol.94
, pp. 1168-1178
-
-
Marx, N.1
Duez, H.2
Fruchart, J.C.3
-
115
-
-
54049125406
-
Atheroprotective effect of human apolipoprotein A5 in a mouse model of mixed dyslipidemia
-
Mansouri RM, Baugé E, Gervois P, et al. Atheroprotective effect of human apolipoprotein A5 in a mouse model of mixed dyslipidemia. Circ Res 2008;103:450-3.
-
(2008)
Circ Res
, vol.103
, pp. 450-453
-
-
Mansouri, R.M.1
Baugé, E.2
Gervois, P.3
-
116
-
-
84903147667
-
Peroxisome proliferator-activated receptor a activation induces hepatic steatosis, suggesting an adverse effect
-
Yan F, Wang Q, Xu C, et al. Peroxisome proliferator-activated receptor a activation induces hepatic steatosis, suggesting an adverse effect. PLoS One 2014;9:e99245.
-
(2014)
PLoS One
, vol.9
, pp. e99245
-
-
Yan, F.1
Wang, Q.2
Xu, C.3
-
117
-
-
84896034306
-
PPAR agonists reduce steatosis in oleic acid-overloaded HepaRG cells
-
Rogue A, Anthérieu S, Vluggens A, et al. PPAR agonists reduce steatosis in oleic acid-overloaded HepaRG cells. Toxicol Appl Pharmacol 2014;276: 73-81.
-
(2014)
Toxicol Appl Pharmacol
, vol.276
, pp. 73-81
-
-
Rogue, A.1
Anthérieu, S.2
Vluggens, A.3
-
118
-
-
84894213660
-
Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of nonalcoholic fatty liver disease
-
Ganji SH, Kukes GD, Lambrecht N, et al. Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of nonalcoholic fatty liver disease. Am J Physiol Gastrointest Liver Physiol 2014;306:G320-7.
-
(2014)
Am J Physiol Gastrointest Liver Physiol
, vol.306
, pp. G320-G327
-
-
Ganji, S.H.1
Kukes, G.D.2
Lambrecht, N.3
-
119
-
-
84904252744
-
Effects of extended-release niacin with laropiprant in high-risk patients
-
HPS 2-THRIVE Collaborative Group
-
HPS 2-THRIVE Collaborative Group, Landray MJ, Haynes R, Hopewell JC, et al. Effects of extended-release niacin with laropiprant in high-risk patients. N Engl J Med 2014;371:203-12.
-
(2014)
N Engl J Med
, vol.371
, pp. 203-212
-
-
Landray, M.J.1
Haynes, R.2
Hopewell, J.C.3
-
120
-
-
84904265666
-
Safety profile of extended-release niacin in the AIM-HIGH trial
-
for the AIM-HIGH Investigators
-
Anderson TJ, Boden WE, Desvigne-Nickens P, et al., for the AIM-HIGH Investigators. Safety profile of extended-release niacin in the AIM-HIGH trial. N Engl J Med 2014;371:288-90.
-
(2014)
N Engl J Med
, vol.371
, pp. 288-290
-
-
Anderson, T.J.1
Boden, W.E.2
Desvigne-Nickens, P.3
-
121
-
-
0015211669
-
Plasma lipid and lipoprotein pattern in in Greenlandic Westcoast Eskimos
-
Bang HO, Dyerberg J, Nielsen A. Plasma lipid and lipoprotein pattern in in Greenlandic Westcoast Eskimos. Lancet 1971;297:1143-5.
-
(1971)
Lancet
, vol.297
, pp. 1143-1145
-
-
Bang, H.O.1
Dyerberg, J.2
Nielsen, A.3
-
122
-
-
84888286731
-
Omega-3 fatty acids: New insights into the pharmacology and biology of docosahexaenoic acid, docosapentaenoic acid, and eicosapentaenoic acid
-
Davidson MH. Omega-3 fatty acids: new insights into the pharmacology and biology of docosahexaenoic acid, docosapentaenoic acid, and eicosapentaenoic acid. Curr Opin Lipidol 2013;24: 467-74.
-
(2013)
Curr Opin Lipidol
, vol.24
, pp. 467-474
-
-
Davidson, M.H.1
-
123
-
-
84901293971
-
Niacin in pharmacological doses alters microRNA expression in skeletal muscle of obese Zucker rats
-
Couturier A, Keller J, Most E, et al. Niacin in pharmacological doses alters microRNA expression in skeletal muscle of obese Zucker rats. PLoS One 2014;9:e98313.
-
(2014)
PLoS One
, vol.9
, pp. e98313
-
-
Couturier, A.1
Keller, J.2
Most, E.3
-
124
-
-
84877069888
-
Nicotinic acid receptor GPR109A is down-regulated in human macrophage-derived foam cells
-
Chai JT, Digby JE, Ruparelia N, et al. Nicotinic acid receptor GPR109A is down-regulated in human macrophage-derived foam cells. PLoS One 2013;8:e62934.
-
(2013)
PLoS One
, vol.8
, pp. e62934
-
-
Chai, J.T.1
Digby, J.E.2
Ruparelia, N.3
-
126
-
-
84907669754
-
Polymorphisms in genes involved in the triglyceride synthesis pathway and marine omega-3 polyunsaturated fatty acid supplementation modulate plasma triglyceride levels
-
Ouellette C, Cormier H, Rudkowska I, et al. Polymorphisms in genes involved in the triglyceride synthesis pathway and marine omega-3 polyunsaturated fatty acid supplementation modulate plasma triglyceride levels. J Nutrigenet Nutrigenomics 2013;6:268-80.
-
(2013)
J Nutrigenet Nutrigenomics
, vol.6
, pp. 268-280
-
-
Ouellette, C.1
Cormier, H.2
Rudkowska, I.3
-
127
-
-
84893916503
-
Omega-3 free fatty acids for the treatment of severe hypertriglyceridemia: The EpanoVa for Lowering Very high triglyceridEs (EVOLVE) trial
-
Kastelein JJ, Maki KC, Susekov A, et al. Omega-3 free fatty acids for the treatment of severe hypertriglyceridemia: the EpanoVa fOr Lowering Very high triglyceridEs (EVOLVE) trial. J Clin Lipidol 2014;8:94-106.
-
(2014)
J Clin Lipidol
, vol.8
, pp. 94-106
-
-
Kastelein, J.J.1
Maki, K.C.2
Susekov, A.3
-
128
-
-
84898890570
-
Docosahexaenoic acid modulates the enterocyte Caco-2 cell expression of microRNAs involved in lipid metabolism
-
Gil-Zamorano J, Martin R, Daimiel L, et al. Docosahexaenoic acid modulates the enterocyte Caco-2 cell expression of microRNAs involved in lipid metabolism. J Nutr 2014;144:575-85.
-
(2014)
J Nutr
, vol.144
, pp. 575-585
-
-
Gil-Zamorano, J.1
Martin, R.2
Daimiel, L.3
-
129
-
-
33744736614
-
Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids
-
Schaeffer L, Gohlke H, Muller M, et al. Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids. Hum Mol Genet 2006;15:1745-56.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1745-1756
-
-
Schaeffer, L.1
Gohlke, H.2
Muller, M.3
-
130
-
-
59249102911
-
Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: The Jackson Heart Study
-
Deo RC, Reich D, Tandon A, et al. Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study. PLoS Genet 2009;5:e1000342.
-
(2009)
PLoS Genet
, vol.5
, pp. e1000342
-
-
Deo, R.C.1
Reich, D.2
Tandon, A.3
-
131
-
-
53849097341
-
FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease
-
Martinelli N, Girelli D, Malerba G, et al. FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease. Am J Clin Nutr 2008;88:941-9.
-
(2008)
Am J Clin Nutr
, vol.88
, pp. 941-949
-
-
Martinelli, N.1
Girelli, D.2
Malerba, G.3
-
132
-
-
79960947310
-
Genetic loci associated with plasma phospholipid n-3 fatty acids: A meta-analysis of genome-wide association studies from the CHARGE Consortium
-
Lemaitre RN, Tanaka T, Tang W, et al. Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. PLoS Genet 2011;7:e1002193.
-
(2011)
PLoS Genet
, vol.7
, pp. e1002193
-
-
Lemaitre, R.N.1
Tanaka, T.2
Tang, W.3
-
133
-
-
33747128489
-
Mechanisms for the hypotriglyceridemic effect of marine omega-3 fatty acids
-
Davidson MH. Mechanisms for the hypotriglyceridemic effect of marine omega-3 fatty acids. Am J Cardiol 2006;98:27i-33i.
-
(2006)
Am J Cardiol
, vol.98
, pp. 27i-33i
-
-
Davidson, M.H.1
-
134
-
-
67549138178
-
Apolipoprotein CIII links dyslipidemia with atherosclerosis
-
Kawakami A, Yoshida M. Apolipoprotein CIII links dyslipidemia with atherosclerosis. J Atheroscler Thromb 2009;16:6-11.
-
(2009)
J Atheroscler Thromb
, vol.16
, pp. 6-11
-
-
Kawakami, A.1
Yoshida, M.2
-
135
-
-
31544455792
-
Fatty acid regulation of hepatic gene transcription
-
Jump DB, Botolin D, Wang Y, et al. Fatty acid regulation of hepatic gene transcription. J Nutr 2005;135:2503-6.
-
(2005)
J Nutr
, vol.135
, pp. 2503-2506
-
-
Jump, D.B.1
Botolin, D.2
Wang, Y.3
-
136
-
-
51449106076
-
ChREBP: A glucoseactivated transcription factor involved in the development of metabolic syndrome
-
Iizuka K, Horikawa Y. ChREBP: a glucoseactivated transcription factor involved in the development of metabolic syndrome. Endocr J 2008;55:617-24.
-
(2008)
Endocr J
, vol.55
, pp. 617-624
-
-
Iizuka, K.1
Horikawa, Y.2
-
137
-
-
84869081008
-
Docosahexaenoic acid suppresses the expression of FoxO and its target genes
-
Chen YJ, Chen CC, Li TK, et al. Docosahexaenoic acid suppresses the expression of FoxO and its target genes. J Nutr Biochem 2012;23:1609-16.
-
(2012)
J Nutr Biochem
, vol.23
, pp. 1609-1616
-
-
Chen, Y.J.1
Chen, C.C.2
Li, T.K.3
-
138
-
-
70349742488
-
Effects of prescription omega-3-acid ethyl esters on lipoprotein particle concentrations, apolipoproteins AI and CIII, and lipoproteinassociated phospholipase A2 mass in statintreated subjects with hypertriglyceridemia
-
Davidson MH, Maki KC, Bays H, et al. Effects of prescription omega-3-acid ethyl esters on lipoprotein particle concentrations, apolipoproteins AI and CIII, and lipoproteinassociated phospholipase A2 mass in statintreated subjects with hypertriglyceridemia. J Clin Lipidol 2009;3:332-40.
-
(2009)
J Clin Lipidol
, vol.3
, pp. 332-340
-
-
Davidson, M.H.1
Maki, K.C.2
Bays, H.3
-
140
-
-
85030396341
-
-
Catabasis Pharmaceuticals Inc., May 1, Accessed September 22, 2014
-
Catabasis Pharmaceuticals, Inc. Catabasis describes modulation of SREBP as mechanism for CAT-2003. May 1, 2014. Available at: http://www. catabasis.com/pdfs/CatabasisATVB2014DataFINAL050114.pdf. Accessed September 22, 2014.
-
(2014)
Catabasis Describes Modulation of SREBP As Mechanism for CAT-2003
-
-
-
141
-
-
84966424401
-
An antisense inhibitor of apolipoprotein C-III substantially decreases fasting apolipoprotein C-III and triglyceride levels in LPL deficiency
-
Gaudet D, Alexander VJ, Brisson D, et al. An antisense inhibitor of apolipoprotein C-III substantially decreases fasting apolipoprotein C-III and triglyceride levels in LPL deficiency. J Clinical Lipidol 2014;8:353-4.
-
(2014)
J Clinical Lipidol
, vol.8
, pp. 353-354
-
-
Gaudet, D.1
Alexander, V.J.2
Brisson, D.3
-
142
-
-
84878637167
-
Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans
-
Graham MJ, Lee RG, Bell TA 3rd, et al. Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans. Circ Res 2013; 112:1479-90.
-
(2013)
Circ Res
, vol.112
, pp. 1479-1490
-
-
Graham, M.J.1
Lee, R.G.2
Bell, T.A.3
-
143
-
-
84878656191
-
Apolipoprotein C-III: Going back to the future for a lipid drug target
-
Huff MW, Hegele RA. Apolipoprotein C-III: going back to the future for a lipid drug target. Circ Res 2013;112:1405-8.
-
(2013)
Circ Res
, vol.112
, pp. 1405-1408
-
-
Huff, M.W.1
Hegele, R.A.2
-
144
-
-
84897584807
-
Severe hypertriglyceridemia with pancreatitis: Thirteen years' treatment with lomitapide
-
Sacks FM, Stanesa M, Hegele RA. Severe hypertriglyceridemia with pancreatitis: thirteen years' treatment with lomitapide. JAMA Intern Med 2014;174:443-7.
-
(2014)
JAMA Intern Med
, vol.174
, pp. 443-447
-
-
Sacks, F.M.1
Stanesa, M.2
Hegele, R.A.3
-
145
-
-
84867372806
-
Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying
-
Ables GP, Yang KJ, Vogel S, et al. Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying. J Lipid Res 2012;53:2364-79.
-
(2012)
J Lipid Res
, vol.53
, pp. 2364-2379
-
-
Ables, G.P.1
Yang, K.J.2
Vogel, S.3
-
146
-
-
57649233035
-
Acylation of acylglycerols by acyl coenzyme A:diacylglycerol acyltransferase 1 (DGAT1). Functional importance of DGAT1 in the intestinal fat absorption
-
Cheng, D, Iqbal J, Devenny J, et al. Acylation of acylglycerols by acyl coenzyme A:diacylglycerol acyltransferase 1 (DGAT1). Functional importance of DGAT1 in the intestinal fat absorption. J Biol Chem 2008;283:29802-11.
-
(2008)
J Biol Chem
, vol.283
, pp. 29802-29811
-
-
Cheng, D.1
Iqbal, J.2
Devenny, J.3
-
147
-
-
79953297691
-
DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes
-
Harris CA, Haas JT, Streeper RS, et al. DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes. J Lipid Res 2011; 52:657-67.
-
(2011)
J Lipid Res
, vol.52
, pp. 657-667
-
-
Harris, C.A.1
Haas, J.T.2
Streeper, R.S.3
-
148
-
-
84901944641
-
The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes
-
Perry RJ, Samuel VT, Petersen KF, et al. The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes. Nature 2014;510:84-91.
-
(2014)
Nature
, vol.510
, pp. 84-91
-
-
Perry, R.J.1
Samuel, V.T.2
Petersen, K.F.3
-
149
-
-
84926299558
-
-
ClinicalTrials.gov, Updated July 3, Accessed September 22, 2014
-
ClinicalTrials.gov. A Randomized, Doubleblind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia Syndrome. Updated July 3, 2014. Available at: http://clinicaltrials.gov/show/NCT01514461. Accessed September 22, 2014.
-
(2014)
A Randomized, Doubleblind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects with Familial Chylomicronemia Syndrome
-
-
-
150
-
-
84899572193
-
The DGAT1 inhibitor pradigastat decreases chylomicron secretion and prevents postprandial triglyceride elevation in humans (abstr)
-
Meyers CD, Serrano-Wu M, Amer A, et al. The DGAT1 inhibitor pradigastat decreases chylomicron secretion and prevents postprandial triglyceride elevation in humans (abstr). J Clin Lipidol 2013;7:285.
-
(2013)
J Clin Lipidol
, vol.7
, pp. 285
-
-
Meyers, C.D.1
Serrano-Wu, M.2
Amer, A.3
-
151
-
-
84860754546
-
Effect of alipogene tiparvovec (AAV1-LPL(S447X)) on postprandial chylomicron metabolism in lipoprotein lipase-deficient patients
-
Carpentier AC, Frisch F, Labbé SM, et al. Effect of alipogene tiparvovec (AAV1-LPL(S447X)) on postprandial chylomicron metabolism in lipoprotein lipase-deficient patients. J Clin Endocrinol Metab 2012;97:1635-44.
-
(2012)
J Clin Endocrinol Metab
, vol.97
, pp. 1635-1644
-
-
Carpentier, A.C.1
Frisch, F.2
Labbé, S.M.3
-
152
-
-
84875962928
-
Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: An open-label trial
-
Gaudet D, Méthot J, Déry S, et al. Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial. Gene Ther 2013;20:361-9.
-
(2013)
Gene Ther
, vol.20
, pp. 361-369
-
-
Gaudet, D.1
Méthot, J.2
Déry, S.3
-
153
-
-
84896320924
-
Immune responses to intramuscular administration of alipogene tiparvovec (AAV1-LPL(S447X)) in a phase II clinical trial of lipoprotein lipase deficiency gene therapy
-
Ferreira V, Twisk J, Kwikkers K, et al. Immune responses to intramuscular administration of alipogene tiparvovec (AAV1-LPL(S447X)) in a phase II clinical trial of lipoprotein lipase deficiency gene therapy. Hum Gene Ther 2014; 25:180-8.
-
(2014)
Hum Gene Ther
, vol.25
, pp. 180-188
-
-
Ferreira, V.1
Twisk, J.2
Kwikkers, K.3
-
155
-
-
84880289352
-
A largely random AAV integration profile after LPLD gene therapy
-
Kaeppel C, Beattie SG, Fronza R, et al. A largely random AAV integration profile after LPLD gene therapy. Nat Med 2013;19:889-91.
-
(2013)
Nat Med
, vol.19
, pp. 889-891
-
-
Kaeppel, C.1
Beattie, S.G.2
Fronza, R.3
|