-
1
-
-
1542344471
-
Fatty acid regulation of gene transcription
-
Jump, D. B. (2004) Fatty acid regulation of gene transcription. Crit. Rev. Clin. Lab. Sci. 41: 41-78.
-
(2004)
Crit. Rev. Clin. Lab. Sci.
, vol.41
, pp. 41-78
-
-
Jump, D.B.1
-
2
-
-
4444242510
-
Control of gene expression by fatty acids
-
Pegorier, J. P., Le May, C. & Girard, J. (2004) Control of gene expression by fatty acids. J. Nutr. 134: 2444S-2449S.
-
(2004)
J. Nutr.
, vol.134
-
-
Pegorier, J.P.1
Le May, C.2
Girard, J.3
-
3
-
-
0033105510
-
Molecular recognition of fatty acids by PPAR
-
Xu, H. E., Lambert, M. H., Montana, V. G., Parks, D. J., Blanchard, S. G., Brown, P. J., Sternbach, D. D., Lehmann, J. M., Wisely, G. B., et al. (1999) Molecular recognition of fatty acids by PPAR. Mol. Cell. 3: 397-403.
-
(1999)
Mol. Cell.
, vol.3
, pp. 397-403
-
-
Xu, H.E.1
Lambert, M.H.2
Montana, V.G.3
Parks, D.J.4
Blanchard, S.G.5
Brown, P.J.6
Sternbach, D.D.7
Lehmann, J.M.8
Wisely, G.B.9
-
4
-
-
0036710140
-
HNF-4γ is a transcription factor that constitutively binds fatty acids
-
Wisely, G. B., Miller, A. B., Davis, R. G., Thornquest, A. D., Jr., Johnson, R., Spitzer, T., Sefler, A., Shearer, B., Moore, J. T., et al. (2002) HNF-4γ is a transcription factor that constitutively binds fatty acids. Structure 10: 1225-1234.
-
(2002)
Structure
, vol.10
, pp. 1225-1234
-
-
Wisely, G.B.1
Miller, A.B.2
Davis, R.G.3
Thornquest Jr., A.D.4
Johnson, R.5
Spitzer, T.6
Sefler, A.7
Shearer, B.8
Moore, J.T.9
-
5
-
-
0037063997
-
Crystal structure of the HNF-4α ligand binding domain in complex with endogenous fatty acid ligand
-
Dhe-Paganon, S., Duda, K., Iwamoto, M., Chi, Y. I. & Shoelson, S. E. (2002) Crystal structure of the HNF-4α ligand binding domain in complex with endogenous fatty acid ligand. J. Biol. Chem. 277: 37973-37976.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 37973-37976
-
-
Dhe-Paganon, S.1
Duda, K.2
Iwamoto, M.3
Chi, Y.I.4
Shoelson, S.E.5
-
6
-
-
0034672081
-
Docosahexaenoic acid, a ligand for RXR in mouse brain
-
Washington, DC
-
de Urquiza, M. A., Liu, S., Sjoberg, M., Zetterstrom, R.H., Griffiths, W., Sjovall, J. & Perlmann, T. (2000) Docosahexaenoic acid, a ligand for RXR in mouse brain. Science (Washington, DC) 290: 2140-2144.
-
(2000)
Science
, vol.290
, pp. 2140-2144
-
-
De Urquiza, M.A.1
Liu, S.2
Sjoberg, M.3
Zetterstrom, R.H.4
Griffiths, W.5
Sjovall, J.6
Perlmann, T.7
-
7
-
-
0035932990
-
Unsaturated fatty acids inhibit transcription of the SREBP-1c gene by antagonizing ligand-dependent activation of the LXR
-
U.S.A.
-
Ou, J., Tu, H., Shan, B., Luk, A., DeBose-Boyd, R. A., Bashmakov, Y., Goldstein, J. L. & Brown, M. S. (2001) Unsaturated fatty acids inhibit transcription of the SREBP-1c gene by antagonizing ligand-dependent activation of the LXR. Proc. Natl. Acad. Sci. U.S.A. 98: 6027-6032.
-
(2001)
Proc. Natl. Acad. Sci.
, vol.98
, pp. 6027-6032
-
-
Ou, J.1
Tu, H.2
Shan, B.3
Luk, A.4
DeBose-Boyd, R.A.5
Bashmakov, Y.6
Goldstein, J.L.7
Brown, M.S.8
-
8
-
-
3042856569
-
A glance at G-protein-coupled receptors for lipid mediators: A growing receptor family with remarkably diverse ligands
-
Kostenis, E. (2004) A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands. Pharmacol. Ther. 102: 243-257.
-
(2004)
Pharmacol. Ther.
, vol.102
, pp. 243-257
-
-
Kostenis, E.1
-
9
-
-
20444484799
-
Comparative biochemical studies of the murine FATP expressed in yeast
-
DiRusso, C. C., Li, H., Darwis, D., Watkins, P. A., Berger, J. & Black, P. N. (2005) Comparative biochemical studies of the murine FATP expressed in yeast. J. Biol. Chem. 280: 16829-16837.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 16829-16837
-
-
DiRusso, C.C.1
Li, H.2
Darwis, D.3
Watkins, P.A.4
Berger, J.5
Black, P.N.6
-
10
-
-
0036321931
-
Do long-chain acyl-CoA synthetases regulate fatty acid entry into synthetic versus degradative pathways?
-
Coleman, R. A., Lewin, T. M., Van Horn, C. G. & Gonzalez-Baró, M. R. (2002) Do long-chain acyl-CoA synthetases regulate fatty acid entry into synthetic versus degradative pathways? J. Nutr. 132: 2123-2126.
-
(2002)
J. Nutr.
, vol.132
, pp. 2123-2126
-
-
Coleman, R.A.1
Lewin, T.M.2
Van Horn, C.G.3
Gonzalez-Baró, M.R.4
-
11
-
-
0043253165
-
The mammalian fatty acid-binding protein multigene family: Molecular and genetic insights into function
-
Hertzel, A. V. & Bernlohr, D. A. (2000) The mammalian fatty acid-binding protein multigene family: molecular and genetic insights into function. Trends Endocrinol. Metab. 11: 175-180.
-
(2000)
Trends Endocrinol. Metab.
, vol.11
, pp. 175-180
-
-
Hertzel, A.V.1
Bernlohr, D.A.2
-
12
-
-
0035956863
-
Fatty acids and hypolipidemic drugs regulate PPARα- and γ-mediated gene transcription via liver fatty acid binding protein: A signaling path to the nucleus
-
U.S.A.
-
Wolfrum, C., Borrmann, C. M., Borchers, T. & Spener, F. (2001) Fatty acids and hypolipidemic drugs regulate PPARα- and γ-mediated gene transcription via liver fatty acid binding protein: a signaling path to the nucleus. Proc. Natl. Acad. Sci. U.S.A. 98: 2323-2328.
-
(2001)
Proc. Natl. Acad. Sci.
, vol.98
, pp. 2323-2328
-
-
Wolfrum, C.1
Borrmann, C.M.2
Borchers, T.3
Spener, F.4
-
13
-
-
0028322154
-
Hepatic phosphatidylcholines: Evidence for synthesis in the rat by extensive reutilization of endogenous acylglycerides
-
Patton, G. M., Fasulo, J. M. & Robins, S. J. (1994) Hepatic phosphatidylcholines: evidence for synthesis in the rat by extensive reutilization of endogenous acylglycerides. J. Lipid Res. 35: 1211-1221.
-
(1994)
J. Lipid Res.
, vol.35
, pp. 1211-1221
-
-
Patton, G.M.1
Fasulo, J.M.2
Robins, S.J.3
-
14
-
-
0036138306
-
The role Acyl-CoA thioesterases play in mediating intracellular lipid metabolism
-
Hunt, M. C. & Alexson, S. E. (2002) The role Acyl-CoA thioesterases play in mediating intracellular lipid metabolism. Prog. Lipid Res. 41: 99-130.
-
(2002)
Prog. Lipid Res.
, vol.41
, pp. 99-130
-
-
Hunt, M.C.1
Alexson, S.E.2
-
15
-
-
0030783119
-
Polyunsaturated fatty acid suppression of hepatic fatty acid synthase and S14 gene expression does not require PPARα
-
Ren, B., Thelen, A. P., Peters, J. M., Gonzalez, F. J. & Jump, D. B. (1997) Polyunsaturated fatty acid suppression of hepatic fatty acid synthase and S14 gene expression does not require PPARα. J. Biol. Chem. 272: 26827-26832.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26827-26832
-
-
Ren, B.1
Thelen, A.P.2
Peters, J.M.3
Gonzalez, F.J.4
Jump, D.B.5
-
16
-
-
0034023449
-
Evidence against the PPARα as the mediator for PUFA suppression of hepatic L-pyruvate kinase gene transcription
-
Pan, D. A., Mater, M. K., Thelen, A. P., Peters, J. M., Gonzalez, F. J. & Jump, D. B. (2000) Evidence against the PPARα as the mediator for PUFA suppression of hepatic L-pyruvate kinase gene transcription. J. Lipid Res. 41: 742-751.
-
(2000)
J. Lipid Res.
, vol.41
, pp. 742-751
-
-
Pan, D.A.1
Mater, M.K.2
Thelen, A.P.3
Peters, J.M.4
Gonzalez, F.J.5
Jump, D.B.6
-
17
-
-
0142103471
-
The role of LXR-α in the fatty acid regulation of hepatic gene expression
-
Pawar, A., Botolin, D., Mangelsdorf, D. J. & Jump, D. B. (2003) The role of LXR-α in the fatty acid regulation of hepatic gene expression. J. Biol. Chem. 278: 40736-40743.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 40736-40743
-
-
Pawar, A.1
Botolin, D.2
Mangelsdorf, D.J.3
Jump, D.B.4
-
18
-
-
21744446895
-
Tissue-specific, nutritional and developmental regulation of rat fatty acid elongases
-
Wang, Y., Botolin, D., Christian, B., Busik, C., Xu, J. & Jump, D. B. (2005) Tissue-specific, nutritional and developmental regulation of rat fatty acid elongases. J. Lipid Res. 46: 706-715.
-
(2005)
J. Lipid Res.
, vol.46
, pp. 706-715
-
-
Wang, Y.1
Botolin, D.2
Christian, B.3
Busik, C.4
Xu, J.5
Jump, D.B.6
-
19
-
-
0141592581
-
Unsaturated fatty acid regulation of PPARα activity in primary rat hepatocytes
-
Pawar, A. & Jump, D. B. (2003) Unsaturated fatty acid regulation of PPARα activity in primary rat hepatocytes. J. Biol. Chem. 278: 35931-35939.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 35931-35939
-
-
Pawar, A.1
Jump, D.B.2
-
20
-
-
0037131234
-
Fatty acid regulation of LXR and PPARα in HEK293 cells
-
Pawar, A., Xu, J., Jerks, E., Mangelsdorf, D. J. & Jump, D. B. (2002) Fatty acid regulation of LXR and PPARα in HEK293 cells. J. Biol. Chem. 277: 39243-39250.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39243-39250
-
-
Pawar, A.1
Xu, J.2
Jerks, E.3
Mangelsdorf, D.J.4
Jump, D.B.5
-
21
-
-
0034686664
-
Metabolism of highly unsaturated n-3 and n-6 fatty acids
-
Sprecher, H. (2000) Metabolism of highly unsaturated n-3 and n-6 fatty acids. Biochim. Biophys. Acta 1486: 219-231.
-
(2000)
Biochim. Biophys. Acta
, vol.1486
, pp. 219-231
-
-
Sprecher, H.1
-
22
-
-
0036164038
-
Dual regulation of mouse Δ5- and Δ6-desaturase gene expression by SREBP-1 and PPARα
-
Matsuzaka, T., Shimano, H., Yahagi, N., Amemiya-Kudo, M., Yoshikawa, T., Hasty, A. H., Tamura, Y., Osuga, J., Okazaki, H. et al. (2002) Dual regulation of mouse Δ5- and Δ6-desaturase gene expression by SREBP-1 and PPARα. J. Lipid Res. 43: 107-114.
-
(2002)
J. Lipid Res.
, vol.43
, pp. 107-114
-
-
Matsuzaka, T.1
Shimano, H.2
Yahagi, N.3
Amemiya-Kudo, M.4
Yoshikawa, T.5
Hasty, A.H.6
Tamura, Y.7
Osuga, J.8
Okazaki, H.9
-
24
-
-
1242314753
-
LXR-mediated increase in ATP-binding cassette transporter A1 expression is attenuated by fatty acids in CaCo-2 cells: Effect on cholesterol efflux to high-density lipoprotein
-
Murthy, S., Born, E., Mathur, S. N. & Field, F. J. (2004) LXR-mediated increase in ATP-binding cassette transporter A1 expression is attenuated by fatty acids in CaCo-2 cells: effect on cholesterol efflux to high-density lipoprotein. Biochem. J. 377: 545-552.
-
(2004)
Biochem. J.
, vol.377
, pp. 545-552
-
-
Murthy, S.1
Born, E.2
Mathur, S.N.3
Field, F.J.4
-
25
-
-
2142756699
-
LXR-mediated activation of macrophage stearoyl-CoA desaturase generates unsaturated fatty acids that destabilize ABCA1
-
Wang, Y., Kurdi-Haidar, B. & Oram, J. F. (2004) LXR-mediated activation of macrophage stearoyl-CoA desaturase generates unsaturated fatty acids that destabilize ABCA1. J. Lipid Res. 45: 972-980.
-
(2004)
J. Lipid Res.
, vol.45
, pp. 972-980
-
-
Wang, Y.1
Kurdi-Haidar, B.2
Oram, J.F.3
-
26
-
-
0037458568
-
Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure
-
Sun, Y., Hao, M., Luo, Y., Liang, C. P., Silver, D. L., Cheng, C., Maxfield, F. R. & Tall, A. R. (2003) Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure. J. Biol. Chem. 278: 5813-5820.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5813-5820
-
-
Sun, Y.1
Hao, M.2
Luo, Y.3
Liang, C.P.4
Silver, D.L.5
Cheng, C.6
Maxfield, F.R.7
Tall, A.R.8
-
27
-
-
0036291460
-
Regulation of the rat SREBP-1c promoter in primary rat hepatocytes
-
Deng, X., Cagen, L. M., Wilcox, H. G., Park, E. A., Raghow, R. & Elam, M. B. (2002) Regulation of the rat SREBP-1c promoter in primary rat hepatocytes. Biochem. Biophys. Res. Commun. 290: 256-262.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.290
, pp. 256-262
-
-
Deng, X.1
Cagen, L.M.2
Wilcox, H.G.3
Park, E.A.4
Raghow, R.5
Elam, M.B.6
-
28
-
-
21644454402
-
Thioesterase activity and acyl-CoA/fatty acid cross talk of HNF-4α
-
Hertz, R., Kalderon, B., Byk, T., Berman, I., Za'tara, G., Mayer, R. & Bar-Tana, J. (2005) Thioesterase activity and acyl-CoA/fatty acid cross talk of HNF-4α. J. Biol. Chem.
-
(2005)
J. Biol. Chem.
-
-
Hertz, R.1
Kalderon, B.2
Byk, T.3
Berman, I.4
Za'tara, G.5
Mayer, R.6
Bar-Tana, J.7
-
29
-
-
0032475841
-
PUFA decrease expression of promoters with sterol regulatory elements by decreasing levels of mature SREBP
-
Worgall, T. S., Sturley, S. L., Seo, T., Osborne, T. F. & Deckelbaum, R. J. (1998) PUFA decrease expression of promoters with sterol regulatory elements by decreasing levels of mature SREBP. J. Biol. Chem. 273: 25537-25540.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25537-25540
-
-
Worgall, T.S.1
Sturley, S.L.2
Seo, T.3
Osborne, T.F.4
Deckelbaum, R.J.5
-
30
-
-
0142027805
-
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
-
U.S.A.
-
Horton, J. D., Shah, N. A., Warrington, J. A., Anderson, N. N., Park, S. W., Brown, M. S. & Goldstein, J. L. (2003) Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes. Proc. Natl. Acad. Sci. U.S.A. 100: 12027-12032.
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 12027-12032
-
-
Horton, J.D.1
Shah, N.A.2
Warrington, J.A.3
Anderson, N.N.4
Park, S.W.5
Brown, M.S.6
Goldstein, J.L.7
-
31
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton, J. D., Goldstein, J. L. & Brown, M. S. (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Investig. 109: 1125-1131.
-
(2002)
J. Clin. Investig.
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
32
-
-
23844530704
-
Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCGFBW7
-
Sundqvist, A., Bengoechea-Alonso, M. T., Ye, X., Lukiyanchuk, Jin, J., Harper, J. W. & Ericsson, J. (2005) Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCGFBW7. Cell Metab. 1: 379-391.
-
(2005)
Cell Metab.
, vol.1
, pp. 379-391
-
-
Sundqvist, A.1
Bengoechea-Alonso, M.T.2
Ye, X.3
Lukiyanchuk4
Jin, J.5
Harper, J.W.6
Ericsson, J.7
-
33
-
-
0032815863
-
Nuclear import of SREBP-2, a basic helix-loop-helix-leucine zipper (bHLH-Zip)-containing transcription factor, occurs through the direct interaction of importin-β with HLH-Zip
-
Nagoshi, E., Imamoto, N., Sato, R. & Yoneda, Y. (1999) Nuclear import of SREBP-2, a basic helix-loop-helix-leucine zipper (bHLH-Zip)-containing transcription factor, occurs through the direct interaction of importin-β with HLH-Zip. Mol. Biol. Cell. 10: 2221-2233.
-
(1999)
Mol. Biol. Cell.
, vol.10
, pp. 2221-2233
-
-
Nagoshi, E.1
Imamoto, N.2
Sato, R.3
Yoneda, Y.4
-
34
-
-
4444315581
-
Selective association of SREBP isoforms with target promoters in vivo
-
Bennett, M. K., Toth, J. I. & Osborne, T. F. (2004) Selective association of SREBP isoforms with target promoters in vivo. J. Biol. Chem. 279: 37360-37367.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 37360-37367
-
-
Bennett, M.K.1
Toth, J.I.2
Osborne, T.F.3
-
35
-
-
0035965231
-
Direct demonstration of rapid degradation of nuclear SREBP by the ubiquitin-proteasome pathway
-
Hirano, Y., Yoshida, M., Shimizu, M. & Sato, R. (2001) Direct demonstration of rapid degradation of nuclear SREBP by the ubiquitin-proteasome pathway. J. Biol. Chem. 276: 36431-36437.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 36431-36437
-
-
Hirano, Y.1
Yoshida, M.2
Shimizu, M.3
Sato, R.4
-
36
-
-
10644239801
-
Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs
-
Adams, C. M., Reitz, J., De Brabander, J. K., Feramisco, J. D., Li, L., Brown, M. S. & Goldstein, J. L. (2004) Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs. J. Biol. Chem. 279: 52772-52780.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 52772-52780
-
-
Adams, C.M.1
Reitz, J.2
De Brabander, J.K.3
Feramisco, J.D.4
Li, L.5
Brown, M.S.6
Goldstein, J.L.7
-
37
-
-
0347356334
-
Analysis of the role of protein kinase B (cAKT) in insulin-dependent induction of glucokinase and sterol regulatory element-binding protein 1 (SREBP1) mRNAs in hepatocytes
-
Ribaux, P. G. & Iynedjian, P. B. (2003) Analysis of the role of protein kinase B (cAKT) in insulin-dependent induction of glucokinase and sterol regulatory element-binding protein 1 (SREBP1) mRNAs in hepatocytes. Biochem. J. 376: 697-705.
-
(2003)
Biochem. J.
, vol.376
, pp. 697-705
-
-
Ribaux, P.G.1
Iynedjian, P.B.2
-
38
-
-
0037453007
-
Liver-specific mRNA for Insig-2 down-regulated by insulin: Implications for fatty acid synthesis
-
U.S.A.
-
Yabe, D., Komuro, R., Liang, G., Goldstein, J. L. & Brown, M. S. (2003) Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis. Proc. Natl. Acad. Sci. U.S.A. 100: 3155-3160.
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 3155-3160
-
-
Yabe, D.1
Komuro, R.2
Liang, G.3
Goldstein, J.L.4
Brown, M.S.5
-
39
-
-
0035971159
-
PUFA suppress hepatic SREBP-1 expression by accelerating transcript decay
-
Xu, J., Teran-Garcia, M., Park, J. H., Nakamura, M. T. & Clarke, S. D. (2001) PUFA suppress hepatic SREBP-1 expression by accelerating transcript decay. J. Biol. Chem. 276: 9800-9807.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9800-9807
-
-
Xu, J.1
Teran-Garcia, M.2
Park, J.H.3
Nakamura, M.T.4
Clarke, S.D.5
-
40
-
-
0037470171
-
Selective proteolytic processing of rat hepatic sterol regulatory SREBP-1 and SREBP-2 during postnatal development
-
Botolin, D. & Jump, D. B. (2003) Selective proteolytic processing of rat hepatic sterol regulatory SREBP-1 and SREBP-2 during postnatal development. J. Biol. Chem. 278: 6959-6962.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 6959-6962
-
-
Botolin, D.1
Jump, D.B.2
|