Etiology and risk of lactescent plasma and severe hypertriglyceridemia

Journal of Clinical Lipidology

Volumn 5, Issue 1, 2011, Pages 37-44

  Tremblay, Karine ^a   Méthot, Julie ^a   Brisson, Diane ^a   Gaudet, Daniel ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Cardiometabolic risk; Chylomicronemia; Pancreatitis; Plasma lactescence; Severe hypertriglyceridemia

Indexed keywords

ANTILIPEMIC AGENT; APOLIPOPROTEIN A5; APOLIPOPROTEIN B; APOLIPOPROTEIN C2; APOLIPOPROTEIN E; CHYLOMICRON; FENOFIBRATE; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; GLYCEROL KINASE; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; HIGH DENSITY LIPOPROTEIN; INTERMEDIATE DENSITY LIPOPROTEIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN; NICOTINIC ACID; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ADULT; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DISEASE ASSOCIATION; DRUG RESPONSE; FAMILIAL HYPERLIPEMIA; FEMALE; GLUCOSE INTOLERANCE; HIGH RISK PATIENT; HUMAN; HUMAN TISSUE; HYPERLIPOPROTEINEMIA TYPE 1; HYPERLIPOPROTEINEMIA TYPE 3; HYPERTENSION; HYPERTRIGLYCERIDEMIA; MAJOR CLINICAL STUDY; MALE; METABOLISM; MULTIPLE REGRESSION; OBESITY; PANCREATITIS; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PHENOTYPE; PLASMA CHARACTERISTICS; PLASMA LACTESCENCE; PRIORITY JOURNAL; RISK ASSESSMENT; SUPERNATANT; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; CARDIOVASCULAR DISEASES; DIABETES COMPLICATIONS; FEMALE; GENOTYPE; GLUCOSE INTOLERANCE; HUMANS; HYPERTRIGLYCERIDEMIA; HYPOGLYCEMIC AGENTS; LIPIDS; MALE; MIDDLE AGED; OBESITY; PANCREATITIS; RISK; RISK FACTORS;

LYCOPERSICON ESCULENTUM;

EID: 79151472006     PISSN: 19332874     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacl.2010.11.004     Document Type: Article

References (24)

1. J.D. Brunzell Clinical practice. Hypertriglyceridemia N Engl J Med 357 2007 1009 1017
2. R.A. Hegele, M.R. Ban, and N. Hsueh A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia Hum Mol Genet 18 2009 4189 4194
3. R.A. Hegele, and R.L. Pollex Hypertriglyceridemia: phenomics and genomics Mol Cell Biochem 326 2009 35 43
4. G. Yuan, K.Z. Al-Shali, and R.A. Hegele Hypertriglyceridemia: its etiology, effects and treatment CMAJ 176 2007 1113 1120
5. G. Ferns, V. Keti, and B. Griffin Investigation and management of hypertriglyceridaemia J Clin Pathol 61 2008 1174 1183
6. W. Tsuang, U. Navaneethan, L. Ruiz, J.B. Palascak, and A. Gelrud Hypertriglyceridemic pancreatitis: presentation and management Am J Gastroenterol 104 2009 984 991
7. M.J. Albrink, E.B. Man, and J.P. Peters The relation of neutral fat to lactescence of serum J Clin Invest 34 1955 147 157
8. W.F. Van Eck, J.P. Peters, and E.B. Man Significance of lactescence in blood serum Metabolism 1 1952 383 395
9. D. Gaudet, J. de Wal, and K. Tremblay Review of the clinical development of alipogene tiparvovec gene therapy for lipoprotein lipase deficiency Atheroscler Suppl 11 2010 55 60
10. D. Brisson, M. Tremblay, J. Methot, K. Tremblay, and D. Gaudet Comparison of the efficacy of fibrates on hypertriglyceridemic phenotypes with different genetic and clinical characteristics Pharmacogenet Genom 20 2010 742 747
11. D.S. Fredrickson, R.I. Levy, and R.S. Lees Fat transport in lipoproteins - an integrated approach to mechanisms and disorders N Engl J Med 276 1967 94 103 contd
12. J.D. Brunzell, W.R. Hazzard, D. Porte Jr., and E.L. Bierman Evidence for a common, saturable, triglyceride removal mechanism for chylomicrons and very low density lipoproteins in man J Clin Invest 52 1973 1578 1585
13. J. St-Pierre, M.C. Vohl, D. Brisson, P. Perron, J.P. Després, T.J. Hudson, and D. Gaudet A sequence variation in the mitochondrial glycerol-3-phosphate dehydrogenase gene is associated with increased plasma glycerol and free fatty acid concentrations among French Canadians Mol Genet Metab 72 2001 209 217
14. D. Gaudet, M.C. Vohl, and P. Julien Relative contribution of low-density lipoprotein receptor and lipoprotein lipase gene mutations to angiographically assessed coronary artery disease among French Canadians Am J Cardiol 82 1998 299 305
15. D. Bhatnagar Erroneous laboratory values due to severe hypertriglyceridemia D.J. Bettridge, D.R. Illngworth, J. Shepherd, Lipoproteins in Health and Disease 1999 Oxford University Press, Arnold Publishers Oxford 745
16. D. Dix, P. Cohen, S. Kingsley, M.J. Lea, J. Senkbeil, and K. Sexton Interference by lactescence in glycohemoglobin analysis Clin Chem 25 1979 494 495
17. R. Franssen, S.G. Young, and F. Peelman Chylomicronemia with low postheparin lipoprotein lipase levels in the setting of GPIHBP1 defects Circ Cardiovasc Genet 3 2010 169 178
18. M. Moret, V. Pruneta-Deloche, A. Sassolas, C. Marcais, and P. Moulin Prevalence and function of anti-lipoprotein lipase auto-antibodies in type V hyperchylomicronemia Atherosclerosis 208 2010 324 327
19. V. Pruneta-Deloche, C. Marcais, and L. Perrot Combination of circulating antilipoprotein lipase (Anti-LPL) antibody and heterozygous S172 fsX179 mutation of LPL gene leading to chronic hyperchylomicronemia J Clin Endocrinol Metab 90 2005 3995 3998
20. J. Brunzell, and S. Deeb Familial lipoprotein lipase deficiency, apo CII deficiency and hepatic lipase deficiency C.R. Scriver, A.L. Beaudet, W.S. Sly, D. Valle, The Metabolic and Molecular Bases of Inherited Disease 8 ed 2001 McGraw-Hill New York 2789 2816
21. C. Marais, B. Verges, and S. Charrire Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment J Clin Invest 115 2005 2862 2869
22. T. Demant, A. Gaw, and G.F. Watts Metabolism of apoB-100-containing lipoproteins in familial hyperchylomicronemia J Lipid Res 34 1993 147 156
23. G.M. Berger, J.H. Van der Westhuyzen, J. Huskisson, F. Bonnici, and H.E. Henderson Chylomicron and very-low-density lipoprotein levels in type I hyperlipoproteinaemia. The role of the liver in determining biochemical phenotype S Afr Med J 61 1982 266 272
24. D. Gaudet, S. Arsenault, and L. Perusse Glycerol as a correlate of impaired glucose tolerance: dissection of a complex system by use of a simple genetic trait Am J Hum Genet 66 2000 1558 1568