Triglyceride-rich lipoprotein lipolysis increases aggregation of endothelial cell membrane microdomains and produces reactive oxygen species

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 295, Issue 1, 2008, Pages

  Wang, Limin ^a   Sapuri Butti, Annapoorna R ^b   Aung, Hnin Hnin ^a   Parikh, Atul N ^b   Rutledge, John C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Endothelial dysfunction; Free fatty acids; Oxidative stress

Indexed keywords

BIOLOGICAL MARKER; CAVEOLIN 1; CHOLERA TOXIN B SUBUNIT; FLUORESCEIN ISOTHIOCYANATE; LIPOPROTEIN; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRIACYLGLYCEROL; CAV1 PROTEIN, HUMAN; CHOLERA TOXIN; CYTOCHROME P450; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENZYME INHIBITOR; FLUORESCENT DYE; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; NOS3 PROTEIN, HUMAN;

AORTA INTIMA; ARTICLE; CELL AGGREGATION; CELL FUNCTION; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; INCUBATION TIME; LIPID RAFT; LIPOLYSIS; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HYPERTRIGLYCERIDEMIA; METABOLISM; PATHOLOGY; PROTEIN TRANSPORT;

CAVEOLIN 1; CELLS, CULTURED; CHOLERA TOXIN; CYTOCHROME P-450 ENZYME SYSTEM; ENDOTHELIAL CELLS; ENZYME INHIBITORS; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HUMANS; HYPERTRIGLYCERIDEMIA; LDL-RECEPTOR RELATED PROTEIN 1; LIPOLYSIS; LIPOPROTEIN LIPASE; LIPOPROTEINS; MEMBRANE MICRODOMAINS; MICROSCOPY, CONFOCAL; NADPH OXIDASE; NITRIC OXIDE SYNTHASE TYPE III; PROTEIN TRANSPORT; REACTIVE OXYGEN SPECIES; TRIGLYCERIDES;

EID: 49849085120     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01366.2007     Document Type: Article

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