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Volumn 34, Issue 24, 2013, Pages

Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction

Author keywords

Genetics; Lipoproteins; Myocardial infarction; Remnant cholesterol; Triglycerides

Indexed keywords

APOLIPOPROTEIN A5; CHOLESTEROL; TRIACYLGLYCEROL;

EID: 84876175810     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehs431     Document Type: Article
Times cited : (364)

References (59)
  • 1
    • 34447511196 scopus 로고    scopus 로고
    • Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
    • Nordestgaard BG, Benn M, Schnohr P, Tybjaerg-Hansen A. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 2007;298:299-308.
    • (2007) JAMA , vol.298 , pp. 299-308
    • Nordestgaard, B.G.1    Benn, M.2    Schnohr, P.3    Tybjaerg-Hansen, A.4
  • 3
    • 79959356255 scopus 로고    scopus 로고
    • Nonfasting cholesterol and triglycerides and association with risk of myocardial infarction and total mortality: The Copenhagen City Heart Study with 31 years of follow-up
    • Langsted A, Freiberg JJ, Tybjaerg-Hansen A, Schnohr P, Jensen GB, Nordestgaard BG. Nonfasting cholesterol and triglycerides and association with risk of myocardial infarction and total mortality: the Copenhagen City Heart Study with 31 years of follow-up. J Intern Med 2011;270:65-75.
    • (2011) J Intern Med , vol.270 , pp. 65-75
    • Langsted, A.1    Freiberg, J.J.2    Tybjaerg-Hansen, A.3    Schnohr, P.4    Jensen, G.B.5    Nordestgaard, B.G.6
  • 6
    • 34447520136 scopus 로고    scopus 로고
    • Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women
    • Bansal S, Buring JE, Rifai N, Mora S, Sacks FM, Ridker PM. Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA 2007; 298:309-316.
    • (2007) JAMA , vol.298 , pp. 309-316
    • Bansal, S.1    Buring, J.E.2    Rifai, N.3    Mora, S.4    Sacks, F.M.5    Ridker, P.M.6
  • 8
    • 0018649439 scopus 로고
    • Atherogenesis: A postprandial phenomenon
    • Zilversmit DB. Atherogenesis: a postprandial phenomenon. Circulation 1979;60: 473-485.
    • (1979) Circulation , vol.60 , pp. 473-485
    • Zilversmit, D.B.1
  • 10
    • 0028903142 scopus 로고
    • Selective retention of VLDL IDL and LDL in the arterial intima of genetically hyperlipidemic rabbits in vivo. Molecular size as a determinant of fractional loss from the intima-inner media
    • Nordestgaard BG, Wootton R, Lewis B. Selective retention of VLDL, IDL, and LDL in the arterial intima of genetically hyperlipidemic rabbits in vivo. Molecular size as a determinant of fractional loss from the intima-inner media. Arterioscler Thromb Vasc Biol 1995;15:534-542.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 534-542
    • Nordestgaard, B.G.1    Wootton, R.2    Lewis, B.3
  • 11
    • 3142581525 scopus 로고    scopus 로고
    • ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis
    • Schaap FG, Rensen PC, Voshol PJ, Vrins C, van der Vliet HN, Chamuleau RA, Havekes LM, Groen AK, van Dijk KW. ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis. J Biol Chem 2004; 279:27941-27947.
    • (2004) J Biol Chem , vol.279 , pp. 27941-27947
    • Schaap, F.G.1    Rensen, P.C.2    Voshol, P.J.3    Vrins, C.4    Van Der Vliet, H.N.5    Chamuleau, R.A.6    Havekes, L.M.7    Groen, A.K.8    Van Dijk, K.W.9
  • 12
    • 20144375048 scopus 로고    scopus 로고
    • Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase
    • Merkel M, Loeffler B, Kluger M, Fabig N, Geppert G, Pennacchio LA, Laatsch A, Heeren J. Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase. J Biol Chem 2005;280:21553-21560.
    • (2005) J Biol Chem , vol.280 , pp. 21553-21560
    • Merkel, M.1    Loeffler, B.2    Kluger, M.3    Fabig, N.4    Geppert, G.5    Pennacchio, L.A.6    Laatsch, A.7    Heeren, J.8
  • 13
  • 15
    • 17144407867 scopus 로고    scopus 로고
    • Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study
    • Lai CQ, Demissie S, Cupples LA, Zhu Y, Adiconis X, Parnell LD, Corella D, Ordovas JM. Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study. J Lipid Res 2004;45: 2096-2105.
    • (2004) J Lipid Res , vol.45 , pp. 2096-2105
    • Lai, C.Q.1    Demissie, S.2    Cupples, L.A.3    Zhu, Y.4    Adiconis, X.5    Parnell, L.D.6    Corella, D.7    Ordovas, J.M.8
  • 16
    • 0345832332 scopus 로고    scopus 로고
    • The APOA5 locus is a strong determinant of plasma triglyceride concentrations across ethnic groups in Singapore
    • Lai CQ, Tai ES, Tan CE, Cutter J, Chew SK, Zhu YP, Adiconis X, Ordovas JM. The APOA5 locus is a strong determinant of plasma triglyceride concentrations across ethnic groups in Singapore. J Lipid Res 2003;44:2365-2373.
    • (2003) J Lipid Res , vol.44 , pp. 2365-2373
    • Lai, C.Q.1    Tai, E.S.2    Tan, C.E.3    Cutter, J.4    Chew, S.K.5    Zhu, Y.P.6    Adiconis, X.7    Ordovas, J.M.8
  • 18
    • 40349113281 scopus 로고    scopus 로고
    • Hypertriglyceridaemia and low plasma HDL in a patient with apolipoprotein A-V deficiency due to a novel mutation in the APOA5 gene
    • Priore OC, Carubbi F, Schaap FG, Bertolini S, Calandra S. Hypertriglyceridaemia and low plasma HDL in a patient with apolipoprotein A-V deficiency due to a novel mutation in the APOA5 gene. J Intern Med 2008;263:450-458.
    • (2008) J Intern Med , vol.263 , pp. 450-458
    • Priore, O.C.1    Carubbi, F.2    Schaap, F.G.3    Bertolini, S.4    Calandra, S.5
  • 21
    • 40849083720 scopus 로고    scopus 로고
    • Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
    • Lawlor DA, Harbord RM, Sterne JA, Timpson N, Davey SG. Mendelian randomization: using genes as instruments for making causal inferences in epidemiology. Stat Med 2008;27:1133-1163.
    • (2008) Stat Med , vol.27 , pp. 1133-1163
    • Lawlor, D.A.1    Harbord, R.M.2    Sterne, J.A.3    Timpson, N.4    Davey, S.G.5
  • 22
    • 79953748675 scopus 로고    scopus 로고
    • Genetic determinants of LDL, lipoprotein( a), triglyceride-rich lipoproteins and HDL: Concordance and discordance with cardiovascular disease risk
    • Nordestgaard BG, Tybjaerg-Hansen A. Genetic determinants of LDL, lipoprotein( a), triglyceride-rich lipoproteins and HDL: concordance and discordance with cardiovascular disease risk. Curr Opin Lipidol 2011;22:113-122.
    • (2011) Curr Opin Lipidol , vol.22 , pp. 113-122
    • Nordestgaard, B.G.1    Tybjaerg-Hansen, A.2
  • 23
    • 0033822124 scopus 로고    scopus 로고
    • Myocardial infarction redefined - A consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction
    • The Joint European Society of Cardiology/American College of Cardiology Committee
    • The Joint European Society of Cardiology/American College of Cardiology Committee. Myocardial infarction redefined-a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. Eur Heart J 2000;21:1502-1513.
    • (2000) Eur Heart J , vol.21 , pp. 1502-1513
  • 24
    • 35448971466 scopus 로고    scopus 로고
    • Universal definition of myocardial infarction
    • Thygesen K, Alpert JS, White HD. Universal definition of myocardial infarction. Eur Heart J 2007;28:2525-2538.
    • (2007) Eur Heart J , vol.28 , pp. 2525-2538
    • Thygesen, K.1    Alpert, J.S.2    White, H.D.3
  • 27
    • 0036841490 scopus 로고    scopus 로고
    • Effect of gender on phenotypic expression of the S447X mutation in LPL: The Copenhagen City Heart Study
    • Wittrup HH, Nordestgaard BG, Steffensen R, Jensen G, Tybjaerg-Hansen A. Effect of gender on phenotypic expression of the S447X mutation in LPL: the Copenhagen City Heart Study. Atherosclerosis 2002;165:119-126.
    • (2002) Atherosclerosis , vol.165 , pp. 119-126
    • Wittrup, H.H.1    Nordestgaard, B.G.2    Steffensen, R.3    Jensen, G.4    Tybjaerg-Hansen, A.5
  • 28
    • 0033567222 scopus 로고    scopus 로고
    • Underestimation of risk associations due to regression dilution in long-term follow-up of prospective studies
    • Clarke R, Shipley M, Lewington S, Youngman L, Collins R, Marmot M, Peto R. Underestimation of risk associations due to regression dilution in long-term follow-up of prospective studies. Am J Epidemiol 1999;150:341-353.
    • (1999) Am J Epidemiol , vol.150 , pp. 341-353
    • Clarke, R.1    Shipley, M.2    Lewington, S.3    Youngman, L.4    Collins, R.5    Marmot, M.6    Peto, R.7
  • 29
    • 84921702413 scopus 로고    scopus 로고
    • Interaction revisited: The difference between two estimates
    • Altman DG, Bland JM. Interaction revisited: the difference between two estimates. BMJ 2003;326:219.
    • (2003) BMJ , vol.326 , pp. 219
    • Altman, D.G.1    Bland, J.M.2
  • 31
    • 0026499897 scopus 로고
    • Influx in vivo of low density, intermediate density, and very low density lipoproteins into aortic intimas of genetically hyperlipidemic rabbit. Roles of plasma concentrations, extent of aortic lesion, and lipoprotein particle size as determinants
    • Nordestgaard BG, Tybjaerg-Hansen A, Lewis B. Influx in vivo of low density, intermediate density, and very low density lipoproteins into aortic intimas of genetically hyperlipidemic rabbits. Roles of plasma concentrations, extent of aortic lesion, and lipoprotein particle size as determinants. Arterioscler Thromb 1992; 12:6-18.
    • (1992) Arterioscler Thromb , vol.12 , pp. 6-18
    • Nordestgaard, B.G.1    Tybjaerg-Hansen, A.2    Lewis, B.3
  • 34
    • 0019981179 scopus 로고
    • Increased lipoprotein-remnant formation in chronic renal failure
    • Nestel PJ, Fidge NH, Tan MH. Increased lipoprotein-remnant formation in chronic renal failure. N Engl J Med 1982;307:329-333.
    • (1982) N Engl J Med , vol.307 , pp. 329-333
    • Nestel, P.J.1    Fidge, N.H.2    Tan, M.H.3
  • 35
    • 0023088890 scopus 로고
    • Increased cholesterol concentration in intermediate density lipoprotein fraction of normolipidemic non-insulin-dependent diabetics
    • Kasama T, Yoshino G, Iwatani I, Iwai M, Hatanaka H, Kazumi T, Oimomi M, Baba S. Increased cholesterol concentration in intermediate density lipoprotein fraction of normolipidemic non-insulin-dependent diabetics. Atherosclerosis 1987;63: 263-266.
    • (1987) Atherosclerosis , vol.63 , pp. 263-266
    • Kasama, T.1    Yoshino, G.2    Iwatani, I.3    Iwai, M.4    Hatanaka, H.5    Kazumi, T.6    Oimomi, M.7    Baba, S.8
  • 36
    • 0001575898 scopus 로고    scopus 로고
    • Type III hyperlipoproteinemia (dyslipoproteinemia): The role of apolipoprotein e in normal and abnormal lipoprotein metabolism
    • Scriver CR, Beaudet AL, Sly WS, Valle D eds New York McGraw-Hill
    • Mahley RW, Rall SC Jr. Type III hyperlipoproteinemia (dyslipoproteinemia) : the role of apolipoprotein E in normal and abnormal lipoprotein metabolism. In: Scriver CR, Beaudet AL, Sly WS, Valle D (eds), The Metabolic and Molecular Bases of Inherited Disease. 8th ed. New York: McGraw-Hill; 2001, p2835-2862.
    • (2001) The Metabolic and Molecular Bases of Inherited Disease. 8th Ed , pp. 2835-2862
    • Mahley, R.W.1    Rall Jr., S.C.2
  • 37
  • 38
    • 60649103338 scopus 로고    scopus 로고
    • The apolipoprotein A5-1131T . C promoter polymorphism in Koreans: Association with plasma APOA5 and serum triglyceride concentrations LDL particle size and coronary artery disease
    • Jang Y, Paik JK, Hyun YJ, Chae JS, Kim JY, Choi JR, Lee SH, Shin DJ, Ordovas JM, Lee JH. The apolipoprotein A5-1131T . C promoter polymorphism in Koreans: association with plasma APOA5 and serum triglyceride concentrations, LDL particle size and coronary artery disease. Clin Chim Acta 2009;402:83-87.
    • (2009) Clin Chim Acta , vol.402 , pp. 83-87
    • Jang, Y.1    Paik, J.K.2    Hyun, Y.J.3    Chae, J.S.4    Kim, J.Y.5    Choi, J.R.6    Lee, S.H.7    Shin, D.J.8    Ordovas, J.M.9    Lee, J.H.10
  • 41
    • 33947146635 scopus 로고    scopus 로고
    • The-1131 T . C and S19W APOA5 gene polymorphisms are associated with high levels of triglycerides and apolipoprotein C-III, but not with coronary artery disease: An angiographic study
    • Martinelli N, Trabetti E, Bassi A, Girelli D, Friso S, Pizzolo F, Sandri M, Malerba G, Pignatti PF, Corrocher R, Olivieri O. The-1131 T . C and S19W APOA5 gene polymorphisms are associated with high levels of triglycerides and apolipoprotein C-III, but not with coronary artery disease: an angiographic study. Atherosclerosis 2007;191:409-417.
    • (2007) Atherosclerosis , vol.191 , pp. 409-417
    • Martinelli, N.1    Trabetti, E.2    Bassi, A.3    Girelli, D.4    Friso, S.5    Pizzolo, F.6    Sandri, M.7    Malerba, G.8    Pignatti, P.F.9    Corrocher, R.10    Olivieri, O.11
  • 42
    • 4143065861 scopus 로고    scopus 로고
    • APOA5 gene polymorphism modulates levels of triglyceride, HDL cholesterol and FERHDL but is not a risk factor for coronary artery disease
    • Lee KW, Ayyobi AF, Frohlich JJ, Hill JS. APOA5 gene polymorphism modulates levels of triglyceride, HDL cholesterol and FERHDL but is not a risk factor for coronary artery disease. Atherosclerosis 2004;176:165-172.
    • (2004) Atherosclerosis , vol.176 , pp. 165-172
    • Lee, K.W.1    Ayyobi, A.F.2    Frohlich, J.J.3    Hill, J.S.4
  • 43
    • 28444457032 scopus 로고    scopus 로고
    • Impact of APOA5/A4/C3 genetic polymorphisms on lipid variables and cardiovascular disease risk in French men
    • Dallongeville J, Cottel D, Montaye M, Codron V, Amouyel P, Helbecque N. Impact of APOA5/A4/C3 genetic polymorphisms on lipid variables and cardiovascular disease risk in French men. Int J Cardiol 2006;106:152-156.
    • (2006) Int J Cardiol , vol.106 , pp. 152-156
    • Dallongeville, J.1    Cottel, D.2    Montaye, M.3    Codron, V.4    Amouyel, P.5    Helbecque, N.6
  • 44
    • 33645103550 scopus 로고    scopus 로고
    • Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
    • Cohen JC, Boerwinkle E, Mosley TH Jr, Hobbs HH. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med 2006;354: 1264-1272.
    • (2006) N Engl J Med , vol.354 , pp. 1264-1272
    • Cohen, J.C.1    Boerwinkle, E.2    Mosley Jr., T.H.3    Hobbs, H.H.4
  • 45
    • 77953309816 scopus 로고    scopus 로고
    • PCSK9 R46L, low-density lipoprotein cholesterol levels, and risk of ischemic heart disease: 3 independent studies and meta-analyses
    • Benn M, Nordestgaard BG, Grande P, Schnohr P, Tybjaerg-Hansen A. PCSK9 R46L, low-density lipoprotein cholesterol levels, and risk of ischemic heart disease: 3 independent studies and meta-analyses. J Am Coll Cardiol 2010;55: 2833-2842.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 2833-2842
    • Benn, M.1    Nordestgaard, B.G.2    Grande, P.3    Schnohr, P.4    Tybjaerg-Hansen, A.5
  • 48
    • 44649140474 scopus 로고    scopus 로고
    • Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease
    • Frikke-Schmidt R, Nordestgaard BG, Stene MC, Sethi AA, Remaley AT, Schnohr P, Grande P, Tybjaerg-Hansen A. Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease. JAMA 2008;299:2524-2532.
    • (2008) JAMA , vol.299 , pp. 2524-2532
    • Frikke-Schmidt, R.1    Nordestgaard, B.G.2    Stene, M.C.3    Sethi, A.A.4    Remaley, A.T.5    Schnohr, P.6    Grande, P.7    Tybjaerg-Hansen, A.8
  • 50
    • 78650052979 scopus 로고    scopus 로고
    • Genetically elevated apolipoprotein A-I, high-density lipoprotein cholesterol levels, and risk of ischemic heart disease
    • Haase CL, Tybjaerg-Hansen A, Grande P, Frikke-Schmidt R. Genetically elevated apolipoprotein A-I, high-density lipoprotein cholesterol levels, and risk of ischemic heart disease. J Clin Endocrinol Metab 2010;95:E500-E510.
    • (2010) J Clin Endocrinol Metab , vol.95
    • Haase, C.L.1    Tybjaerg-Hansen, A.2    Grande, P.3    Frikke-Schmidt, R.4
  • 54
    • 84894014785 scopus 로고    scopus 로고
    • www.roche.com/media/media-releases/med-cor-2012-05-07.htm.
  • 57
    • 0028361107 scopus 로고
    • Role of plasma triglyceride in the regulation of plasma low density lipoprotein (LDL) subfractions: Relative contribution of small, dense LDL to coronary heart disease risk
    • Griffin BA, Freeman DJ, Tait GW, Thomson J, Caslake MJ, Packard CJ, Shepherd J. Role of plasma triglyceride in the regulation of plasma low density lipoprotein (LDL) subfractions: relative contribution of small, dense LDL to coronary heart disease risk. Atherosclerosis 1994;106:241-253.
    • (1994) Atherosclerosis , vol.106 , pp. 241-253
    • Griffin, B.A.1    Freeman, D.J.2    Tait, G.W.3    Thomson, J.4    Caslake, M.J.5    Packard, C.J.6    Shepherd, J.7
  • 58
    • 82955168412 scopus 로고    scopus 로고
    • HDL-C: Role as a risk modifier
    • Barter P. HDL-C: role as a risk modifier. Atheroscler Suppl 2011;12:267-270.
    • (2011) Atheroscler Suppl , vol.12 , pp. 267-270
    • Barter, P.1
  • 59
    • 57149133676 scopus 로고    scopus 로고
    • Fasting and nonfasting lipid levels: Influence of normal food intake on lipids, lipoproteins, apolipoproteins, and cardiovascular risk prediction
    • Langsted A, Freiberg JJ, Nordestgaard BG. Fasting and nonfasting lipid levels: influence of normal food intake on lipids, lipoproteins, apolipoproteins, and cardiovascular risk prediction. Circulation 2008;118:2047-2056.
    • (2008) Circulation , vol.118 , pp. 2047-2056
    • Langsted, A.1    Freiberg, J.J.2    Nordestgaard, B.G.3


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