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Volumn 46, Issue 2, 2005, Pages 297-306

Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL

Author keywords

Apolipoprotein C I; Fatty acids; Lipid metabolism; Lipoprotein lipase; Triglycerides; Very low density lipoprotein

Indexed keywords

APOLIPOPROTEIN C1; LIPOPROTEIN RECEPTOR; TRIACYLGLYCEROL; TRITIUM; VERY LOW DENSITY LIPOPROTEIN;

EID: 13944253941     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: 10.1194/jlr.M400301-JLR200     Document Type: Article
Times cited : (117)

References (59)
  • 1
    • 0022339844 scopus 로고
    • Localization of genes encoding apolipoproteins CI, CII, and E to the p13-cen region of human chromosome 19
    • Scott, J., T. J. Knott, D. J. Shaw, and J. D. Brook. 1985. Localization of genes encoding apolipoproteins CI, CII, and E to the p13-cen region of human chromosome 19. Hum. Genet. 71: 144-146.
    • (1985) Hum. Genet. , vol.71 , pp. 144-146
    • Scott, J.1    Knott, T.J.2    Shaw, D.J.3    Brook, J.D.4
  • 2
    • 0023914276 scopus 로고
    • Two copies of the human apolipoprotein C-I gene are linked closely to the apolipoprotein E gene
    • Lauer, S. J., D. Walker, N. A. Elshourbagy, C. A. Reardon, B. Levy-Wilson, and J. M. Taylor. 1988. Two copies of the human apolipoprotein C-I gene are linked closely to the apolipoprotein E gene. J. Biol. Chem. 263: 7277-7286.
    • (1988) J. Biol. Chem. , vol.263 , pp. 7277-7286
    • Lauer, S.J.1    Walker, D.2    Elshourbagy, N.A.3    Reardon, C.A.4    Levy-Wilson, B.5    Taylor, J.M.6
  • 3
    • 0037968932 scopus 로고    scopus 로고
    • Plasma concentration and lipoprotein distribution of ApoC-I is dependent on ApoE genotype rather than the Hpa I ApoC-I promoter polymorphism
    • Cohn, J. S., M. Tremblay, L. Boulet, H. Jacques, J. Davignon, M. Roy, and L. Bernier. 2003. Plasma concentration and lipoprotein distribution of ApoC-I is dependent on ApoE genotype rather than the Hpa I ApoC-I promoter polymorphism. Atherosclerosis. 169: 63-70.
    • (2003) Atherosclerosis , vol.169 , pp. 63-70
    • Cohn, J.S.1    Tremblay, M.2    Boulet, L.3    Jacques, H.4    Davignon, J.5    Roy, M.6    Bernier, L.7
  • 4
    • 0016409177 scopus 로고
    • The complete amino acid sequence of C-I (apoLp-Ser), an apolipoprotein from human very low density lipoproteins
    • Shulman, R. S., P. N. Herbert, K. Wehrly, and D. S. Fredrickson. 1975. The complete amino acid sequence of C-I (apoLp-Ser), an apolipoprotein from human very low density lipoproteins. J. Biol. Chem. 250: 182-190.
    • (1975) J. Biol. Chem. , vol.250 , pp. 182-190
    • Shulman, R.S.1    Herbert, P.N.2    Wehrly, K.3    Fredrickson, D.S.4
  • 5
    • 0032941603 scopus 로고    scopus 로고
    • A common Hpa I RFLP of apolipoprotein C-I increases gene transcription and exhibits an ethnically distinct pattern of linkage disequilibrium with the alleles of apolipoprotein E
    • Xu, Y., L. Berglund, R. Ramakrishnan, R. Mayeux, C. Ngai, S. Holleran, B. Tycko, T. Leff, and N. S. Shachter. 1999. A common Hpa I RFLP of apolipoprotein C-I increases gene transcription and exhibits an ethnically distinct pattern of linkage disequilibrium with the alleles of apolipoprotein E. J. Lipid Res. 40: 50-58.
    • (1999) J. Lipid Res. , vol.40 , pp. 50-58
    • Xu, Y.1    Berglund, L.2    Ramakrishnan, R.3    Mayeux, R.4    Ngai, C.5    Holleran, S.6    Tycko, B.7    Leff, T.8    Shachter, N.S.9
  • 6
    • 12444269979 scopus 로고    scopus 로고
    • Apolipoprotein E and apolipoprotein CI polymorphisms in the Czech population: Almost complete linkage disequilibrium of the less frequent alleles of both polymorphisms
    • Hubacek, J. A., J. Pitha, V. Adamkova, Z. Skodova, V. Lanska, and R. Poledne. 2003. Apolipoprotein E and apolipoprotein CI polymorphisms in the Czech population: almost complete linkage disequilibrium of the less frequent alleles of both polymorphisms. Physiol. Res. 52: 195-200.
    • (2003) Physiol. Res. , vol.52 , pp. 195-200
    • Hubacek, J.A.1    Pitha, J.2    Adamkova, V.3    Skodova, Z.4    Lanska, V.5    Poledne, R.6
  • 7
    • 0031015859 scopus 로고    scopus 로고
    • Reduced very-low-density lipoprotein fractional catabolic rate in apolipoprotein Cl-deficient mice
    • Jong, M. C., J. H. van Ree, V. E. Dahlmans, R. R. Frants, M. H. Hofker, and L. M. Havekes. 1997. Reduced very-low-density lipoprotein fractional catabolic rate in apolipoprotein Cl-deficient mice. Biochem. J. 321: 445-450.
    • (1997) Biochem. J. , vol.321 , pp. 445-450
    • Jong, M.C.1    Van Ree, J.H.2    Dahlmans, V.E.3    Frants, R.R.4    Hofker, M.H.5    Havekes, L.M.6
  • 9
    • 0029851509 scopus 로고    scopus 로고
    • In the absence of the low density lipoprotein receptor, human apolipoprotein Cl overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway
    • Jong, M. C., V. E. Dahlmans, P. J. van Gorp, K. W. van Dijk, M. L. Breuer, M. H. Hofker, and L. M. Havekes. 1996. In the absence of the low density lipoprotein receptor, human apolipoprotein Cl overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway. J. Clin. Invest. 98: 2259-2267.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2259-2267
    • Jong, M.C.1    Dahlmans, V.E.2    Van Gorp, P.J.3    Van Dijk, K.W.4    Breuer, M.L.5    Hofker, M.H.6    Havekes, L.M.7
  • 12
    • 0016814761 scopus 로고
    • Effect of the human plasma apolipoproteins and phosphatidylcholine acyl donor on the activity of lecithin:cholesterol acyltransferase
    • Soutar, A. K., C. W. Garner, H. N. Baker, J. T. Sparrow, R. L. Jackson, A. M. Gotto, and L. C. Smith. 1975. Effect of the human plasma apolipoproteins and phosphatidylcholine acyl donor on the activity of lecithin:cholesterol acyltransferase. Biochemistry. 14: 3057-3064.
    • (1975) Biochemistry , vol.14 , pp. 3057-3064
    • Soutar, A.K.1    Garner, C.W.2    Baker, H.N.3    Sparrow, J.T.4    Jackson, R.L.5    Gotto, A.M.6    Smith, L.C.7
  • 13
    • 0015934581 scopus 로고
    • Cofactor activity of protein components of human very low density lipoproteins in the hydrolysis of triglycerides by lipoprotein lipase from different sources
    • Havel, R. J., C. J. Fielding, T. Olivecrona, V. G. Shore, P. E. Fielding, and T. Egelrud. 1973. Cofactor activity of protein components of human very low density lipoproteins in the hydrolysis of triglycerides by lipoprotein lipase from different sources. Biochemistry. 12: 1828-1833.
    • (1973) Biochemistry , vol.12 , pp. 1828-1833
    • Havel, R.J.1    Fielding, C.J.2    Olivecrona, T.3    Shore, V.G.4    Fielding, P.E.5    Egelrud, T.6
  • 14
    • 0017072997 scopus 로고
    • Effect of serum and C-apoproteins from very low density lipoproteins on human postheparin plasma hepatic lipase
    • Kinnunen, P. K., and C. Ehnolm. 1976. Effect of serum and C-apoproteins from very low density lipoproteins on human postheparin plasma hepatic lipase. FEBS Lett. 65: 354-357.
    • (1976) FEBS Lett. , vol.65 , pp. 354-357
    • Kinnunen, P.K.1    Ehnolm, C.2
  • 15
    • 1842855016 scopus 로고    scopus 로고
    • Overexpression of apoC-1 in apoE-null mice: Severe hypertriglyceridemia due to inhibition of hepatic lipase
    • Conde-Knape, K., A. Bensadoun, J. H. Sobel, J. S. Cohn, and N. S. Shachter. 2002. Overexpression of apoC-1 in apoE-null mice: severe hypertriglyceridemia due to inhibition of hepatic lipase. J. Lipid Res. 43: 2136-2145.
    • (2002) J. Lipid Res. , vol.43 , pp. 2136-2145
    • Conde-Knape, K.1    Bensadoun, A.2    Sobel, J.H.3    Cohn, J.S.4    Shachter, N.S.5
  • 16
    • 0030922572 scopus 로고    scopus 로고
    • Hepatic lipase deficiency increases plasma cholesterol but reduces susceptibility to atherosclerosis in apolipoprotein E-deficient mice
    • Mezdour, H., R. Jones, C. Dengremont, G. Castro, and N. Maeda. 1997. Hepatic lipase deficiency increases plasma cholesterol but reduces susceptibility to atherosclerosis in apolipoprotein E-deficient mice. J. Biol. Chem. 272: 13570-13575.
    • (1997) J. Biol. Chem. , vol.272 , pp. 13570-13575
    • Mezdour, H.1    Jones, R.2    Dengremont, C.3    Castro, G.4    Maeda, N.5
  • 19
    • 0029120041 scopus 로고
    • Expression of human lecithin-cholesterol acyltransferase in transgenic mice. Effect of human apolipoprotein AI and human apolipoprotein AII on plasma lipoprotein cholesterol metabolism
    • Francone, O. L., E. L. Gong, D. S. Ng, C. J. Fielding, and E. M. Rubin. 1995. Expression of human lecithin-cholesterol acyltransferase in transgenic mice. Effect of human apolipoprotein AI and human apolipoprotein AII on plasma lipoprotein cholesterol metabolism. J. Clin. Invest. 96: 1440-1448.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1440-1448
    • Francone, O.L.1    Gong, E.L.2    Ng, D.S.3    Fielding, C.J.4    Rubin, E.M.5
  • 20
    • 0021798836 scopus 로고
    • Inhibitory effects of C apolipoproteins from rats and humans on the uptake of triglycericle-rich lipoproteins and their remnants by the perfused rat liver
    • Windler, E., and R. J. Havel. 1985. Inhibitory effects of C apolipoproteins from rats and humans on the uptake of triglycericle-rich lipoproteins and their remnants by the perfused rat liver. J. Lipid Res. 26: 556-565.
    • (1985) J. Lipid Res. , vol.26 , pp. 556-565
    • Windler, E.1    Havel, R.J.2
  • 21
    • 0020395231 scopus 로고
    • The effect of human C apolipoproteins on the in vitro hepatic metabolism of triglyceride emulsions in the rat
    • Quarfordt, S. H., G. Michalopoulos, and B. Schirmer. 1982. The effect of human C apolipoproteins on the in vitro hepatic metabolism of triglyceride emulsions in the rat. J Biol. Chem. 257: 14642-14647.
    • (1982) J Biol. Chem. , vol.257 , pp. 14642-14647
    • Quarfordt, S.H.1    Michalopoulos, G.2    Schirmer, B.3
  • 22
    • 0025950963 scopus 로고
    • Mechanisms of inhibition by apolipoprotein C of apolipoprotein E-dependent cellular metabolism of human triglyceride-rich lipoproteins through the low density lipoprotein receptor pathway
    • Sehayek, E., and S. Eisenberg. 1991. Mechanisms of inhibition by apolipoprotein C of apolipoprotein E-dependent cellular metabolism of human triglyceride-rich lipoproteins through the low density lipoprotein receptor pathway. J. Biol. Chem. 266: 18259-18267.
    • (1991) J. Biol. Chem. , vol.266 , pp. 18259-18267
    • Sehayek, E.1    Eisenberg, S.2
  • 23
    • 0025611153 scopus 로고
    • Apolipoprotein C-I modulates the interaction of apolipoprotein E with beta-migrating very low density lipoproteins (beta-VLDL) and inhibits binding of beta-VLDL to low density lipoprotein receptor-related protein
    • Weisgraber, K. H., R. W. Mahley, R. C. Kowal, J. Herz, J. L. Goldstein, and M. S. Brown. 1990. Apolipoprotein C-I modulates the interaction of apolipoprotein E with beta-migrating very low density lipoproteins (beta-VLDL) and inhibits binding of beta-VLDL to low density lipoprotein receptor-related protein. J. Biol. Chem. 265: 22453-22459.
    • (1990) J. Biol. Chem. , vol.265 , pp. 22453-22459
    • Weisgraber, K.H.1    Mahley, R.W.2    Kowal, R.C.3    Herz, J.4    Goldstein, J.L.5    Brown, M.S.6
  • 24
    • 0033104838 scopus 로고    scopus 로고
    • Reversal of hyperlipidaemia in apolipoprotein Cl transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor
    • Jong, M. C., K. W. van Dijk, V. E. Dahlmans, H. van der Boom, K. Kobayashi, K. Oka, G. Siest, L. Chan, M. H. Hofker, and L. M. Havekes. 1999. Reversal of hyperlipidaemia in apolipoprotein Cl transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor. Biochem. J. 338: 281-287.
    • (1999) Biochem. J. , vol.338 , pp. 281-287
    • Jong, M.C.1    Van Dijk, K.W.2    Dahlmans, V.E.3    Van Der Boom, H.4    Kobayashi, K.5    Oka, K.6    Siest, G.7    Chan, L.8    Hofker, M.H.9    Havekes, L.M.10
  • 25
    • 0026725757 scopus 로고
    • Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
    • Plump, A. S., J. D. Smith, T. Hayek, K. Aalto-Setala, A. Walsh, J. G. Verstuyft, E. M. Rubin, and J. L. Breslow. 1992. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell. 71: 343-353.
    • (1992) Cell , vol.71 , pp. 343-353
    • Plump, A.S.1    Smith, J.D.2    Hayek, T.3    Aalto-Setala, K.4    Walsh, A.5    Verstuyft, J.G.6    Rubin, E.M.7    Breslow, J.L.8
  • 27
    • 0027319705 scopus 로고
    • Analysis of techniques to obtain plasma for measurement of levels of free fatty acids
    • Zambon, A., S. I. Hashimoto, and J. D. Brunzell. 1993. Analysis of techniques to obtain plasma for measurement of levels of free fatty acids. J. Lipid Res. 34: 1021-1028.
    • (1993) J. Lipid Res. , vol.34 , pp. 1021-1028
    • Zambon, A.1    Hashimoto, S.I.2    Brunzell, J.D.3
  • 29
    • 0017066469 scopus 로고
    • The inhibition in vivo of lipoprotein lipase (clearing-factor lipase) activity by Triton WR-1339
    • Borensztajn, J., M. S. Rone, and T. J. Kotlar. 1976. The inhibition in vivo of lipoprotein lipase (clearing-factor lipase) activity by Triton WR-1339. Biochem. J. 156: 539-543.
    • (1976) Biochem. J. , vol.156 , pp. 539-543
    • Borensztajn, J.1    Rone, M.S.2    Kotlar, T.J.3
  • 30
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh, E. G., and W. J. Dyer. 1959. A rapid method of total lipid extraction and purification. Can. J. Med. Sci. 37: 911-917.
    • (1959) Can. J. Med. Sci. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 31
    • 0033965336 scopus 로고    scopus 로고
    • Postprandial chylomicron formation and fat absorption in multidrug resistance gene 2 P-glycoprotein-deficient mice
    • Voshol, P. J., D. M. Minich, R. Havinga, R. P. Elferink, H. J. Verkade, A. K. Groen, and F. Kuipers. 2000. Postprandial chylomicron formation and fat absorption in multidrug resistance gene 2 P-glycoprotein-deficient mice. Gastroenterology. 118: 173-182.
    • (2000) Gastroenterology , vol.118 , pp. 173-182
    • Voshol, P.J.1    Minich, D.M.2    Havinga, R.3    Elferink, R.P.4    Verkade, H.J.5    Groen, A.K.6    Kuipers, F.7
  • 33
    • 0031010389 scopus 로고    scopus 로고
    • Particle size determines the specificity of apolipoprotein E-containing triglyceride-rich emulsions for the LDL receptor versus hepatic remnant receptor in vivo
    • Rensen, P. C., N, Herijgers, M. H. Netscher, S. C. Meskers, M. van Eck, and T. J. van Berkel. 1997. Particle size determines the specificity of apolipoprotein E-containing triglyceride-rich emulsions for the LDL receptor versus hepatic remnant receptor in vivo. J. Lipid Res. 38: 1070-1084.
    • (1997) J. Lipid Res. , vol.38 , pp. 1070-1084
    • Rensen, P.C.1    Herijgers, N.2    Netscher, M.H.3    Meskers, S.C.4    Van Eck, M.5    Van Berkel, T.J.6
  • 34
    • 0034749662 scopus 로고    scopus 로고
    • Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice
    • Jong, M. C., P. C. Rensen, V. E. Dahlmans, H. van der Boom, T. J. van Berkel, and L. M. Havekes. 2001. Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice. J. Lipid Res. 42: 1578-1585.
    • (2001) J. Lipid Res. , vol.42 , pp. 1578-1585
    • Jong, M.C.1    Rensen, P.C.2    Dahlmans, V.E.3    Van Der Boom, H.4    Van Berkel, T.J.5    Havekes, L.M.6
  • 35
    • 0025357576 scopus 로고
    • Rapid and simple isolation procedure for lipoprotein lipase from human milk
    • Zechner, R. 1990. Rapid and simple isolation procedure for lipoprotein lipase from human milk. Biochim. Biophys. Acta. 1044: 20-25.
    • (1990) Biochim. Biophys. Acta , vol.1044 , pp. 20-25
    • Zechner, R.1
  • 36
    • 15844414655 scopus 로고    scopus 로고
    • Apolipoprotein E effectively inhibits lipoprotein lipase-mediated lipolysis of chylomicion-like triglyceride-rich lipid emulsions in vitro and in vivo
    • Rensen, P. C., and T. J. van Berkel. 1996. Apolipoprotein E effectively inhibits lipoprotein lipase-mediated lipolysis of chylomicion-like triglyceride-rich lipid emulsions in vitro and in vivo. J. Biol. Chem. 271:14791-14799.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14791-14799
    • Rensen, P.C.1    Van Berkel, T.J.2
  • 37
    • 3142581525 scopus 로고    scopus 로고
    • ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis
    • Schaap, F. G., P. C. Rensen, P. J. Voshol, C. Vrins, H. N. van der Vliet, R. A. Chamuleau, L. M. Havekes, A. K. Groen, and K. W. van Dijk. 2004. ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein- triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis. J Biol. Chem. 279: 27941-27947.
    • (2004) J Biol. Chem. , vol.279 , pp. 27941-27947
    • Schaap, F.G.1    Rensen, P.C.2    Voshol, P.J.3    Vrins, C.4    Van Der Vliet, H.N.5    Chamuleau, R.A.6    Havekes, L.M.7    Groen, A.K.8    Van Dijk, K.W.9
  • 39
    • 0021954138 scopus 로고
    • Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III
    • Wang, C. S., W. J. McConathy, H. U. Kloer, and P. Alaupovic. 1985. Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III. J. Clin. Invest. 75: 384-390.
    • (1985) J. Clin. Invest. , vol.75 , pp. 384-390
    • Wang, C.S.1    McConathy, W.J.2    Kloer, H.U.3    Alaupovic, P.4
  • 40
    • 0026748770 scopus 로고
    • Inhibition of lipoprotein lipase activity by synthetic peptides of apolipoprotein C-III
    • McConathy, W. J., J. C. Gesquiere, H. Bass, A. Tartar, J. C. Fruchart, and C. S. Wang. 1992. Inhibition of lipoprotein lipase activity by synthetic peptides of apolipoprotein C-III. J. Lipid Res. 33: 995-1003.
    • (1992) J. Lipid Res. , vol.33 , pp. 995-1003
    • McConathy, W.J.1    Gesquiere, J.C.2    Bass, H.3    Tartar, A.4    Fruchart, J.C.5    Wang, C.S.6
  • 41
    • 0025990629 scopus 로고
    • Recognition of chylomicron remnants and beta-migrating very-low-density lipoproteins by the remnant receptor of parenchymal liver cells is distinct from the liver alpha 2-macroglobulin-recognition site
    • van Dijk, M. C., G. J. Ziere, W. Boers, C. Linthorst, M. K. Bijsterbosch, and T. J. van Berkel. 1991. Recognition of chylomicron remnants and beta-migrating very-low-density lipoproteins by the remnant receptor of parenchymal liver cells is distinct from the liver alpha 2-macroglobulin- recognition site. Biochem. J. 279: 863-870.
    • (1991) Biochem. J. , vol.279 , pp. 863-870
    • Van Dijk, M.C.1    Ziere, G.J.2    Boers, W.3    Linthorst, C.4    Bijsterbosch, M.K.5    Van Berkel, T.J.6
  • 42
    • 0034534981 scopus 로고    scopus 로고
    • Human apolipoprotein C-I accounts for the ability of plasma high density lipoproteins to inhibit the cholesteryl ester transfer protein activity
    • Gautier, T., D. Masson, J. P. de Barros, A. Athias, P. Gambert, D. Aunis, M. H. Metz-Boutigue, and L. Lagrost. 2000. Human apolipoprotein C-I accounts for the ability of plasma high density lipoproteins to inhibit the cholesteryl ester transfer protein activity. J. Biol. Chem. 275: 37504-37509.
    • (2000) J. Biol. Chem. , vol.275 , pp. 37504-37509
    • Gautier, T.1    Masson, D.2    De Barros, J.P.3    Athias, A.4    Gambert, P.5    Aunis, D.6    Metz-Boutigue, M.H.7    Lagrost, L.8
  • 44
    • 0025101682 scopus 로고
    • Genetic heterogeneity of lipoproteins in inbred strains of mice: Analysis by gel-permeation chromatography
    • Jiao, S., T. G. Cole, R. T. Kitchens, B. Pfleger, and G. Schonfeld. 1990. Genetic heterogeneity of lipoproteins in inbred strains of mice: analysis by gel-permeation chromatography. Metabolism. 39: 155-160.
    • (1990) Metabolism , vol.39 , pp. 155-160
    • Jiao, S.1    Cole, T.G.2    Kitchens, R.T.3    Pfleger, B.4    Schonfeld, G.5
  • 46
    • 0025302165 scopus 로고
    • Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein
    • Kowal, R. C., J. Herz, K. H. Weisgraber, R. W. Mahley, M. S. Brown, and J. L. Goldstein. 1990. Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein. J. Biol. Chem. 265: 10771-10779.
    • (1990) J. Biol. Chem. , vol.265 , pp. 10771-10779
    • Kowal, R.C.1    Herz, J.2    Weisgraber, K.H.3    Mahley, R.W.4    Brown, M.S.5    Goldstein, J.L.6
  • 47
    • 0028144804 scopus 로고
    • Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins
    • Fan, J., J. Wang, A. Bensadoun, S. J. Lauer, Q. Dang, R. W. Mahley, and J. M. Taylor. 1994. Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins. Proc. Natl. Acad. Sci. USA. 91: 8724-8728.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8724-8728
    • Fan, J.1    Wang, J.2    Bensadoun, A.3    Lauer, S.J.4    Dang, Q.5    Mahley, R.W.6    Taylor, J.M.7
  • 49
    • 0028988781 scopus 로고
    • Lipases and lecithin:cholesterol acyltransferase in the control of lipoprotein metabolism
    • Applebaum-Bowden, D. 1995. Lipases and lecithin:cholesterol acyltransferase in the control of lipoprotein metabolism. Curr. Opin. Lipidol. 6: 130-135.
    • (1995) Curr. Opin. Lipidol. , vol.6 , pp. 130-135
    • Applebaum-Bowden, D.1
  • 50
    • 0015530365 scopus 로고
    • Inhibition of lipoprotein lipase by an apoprotein of human very low density lipoprotein
    • Brown, W. V., and M. L. Baginsky. 1972. Inhibition of lipoprotein lipase by an apoprotein of human very low density lipoprotein. Biochem. Biophys. Res. Commun. 46: 375-382.
    • (1972) Biochem. Biophys. Res. Commun. , vol.46 , pp. 375-382
    • Brown, W.V.1    Baginsky, M.L.2
  • 51
    • 0025030698 scopus 로고
    • Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice
    • Ito, Y., N. Azrolan, A. O'Connell, A. Walsh, and J. L. Breslow. 1990. Hypertriglyceridemia as a result of human apo CIII gene expression in transgenic mice. Science. 249: 790-793.
    • (1990) Science , vol.249 , pp. 790-793
    • Ito, Y.1    Azrolan, N.2    O'Connell, A.3    Walsh, A.4    Breslow, J.L.5
  • 52
    • 0029791717 scopus 로고    scopus 로고
    • Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apoC-III transgenic mice
    • Aalto-Setälä, K., P. H. Weinstock, C. L. Bisgaier, L. Wu, J. D. Smith, and J. L. Breslow. 1996. Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apoC-III transgenic mice. J. Lipid Res. 37: 1802-1811.
    • (1996) J. Lipid Res. , vol.37 , pp. 1802-1811
    • Aalto-Setälä, K.1    Weinstock, P.H.2    Bisgaier, C.L.3    Wu, L.4    Smith, J.D.5    Breslow, J.L.6
  • 53
    • 0027296725 scopus 로고
    • Overexpression of human lipoprotein lipase in transgenic mice. Resistance to diet-induced hypertriglyceridemia and hypercholesterolemia
    • Shimada, M., H. Shimano, T. Gotoda, K. Yamamoto, M. Kawamura, T. Inaba, Y. Yazaki, and N. Yamada. 1993. Overexpression of human lipoprotein lipase in transgenic mice. Resistance to diet-induced hypertriglyceridemia and hypercholesterolemia. J. Biol. Chem. 268: 17924-17929.
    • (1993) J. Biol. Chem. , vol.268 , pp. 17924-17929
    • Shimada, M.1    Shimano, H.2    Gotoda, T.3    Yamamoto, K.4    Kawamura, M.5    Inaba, T.6    Yazaki, Y.7    Yamada, N.8
  • 55
    • 0029079312 scopus 로고
    • COOH-terminal disruption of lipoprotein lipase in mice is lethal in homozygotes, but heterozygotes have elevated triglycerides and impaired enzyme activity
    • Coleman, T., R. L. Seip, J. M. Gimble, D. Lee, N. Maeda, and C. F. Semenkovich. 1995. COOH-terminal disruption of lipoprotein lipase in mice is lethal in homozygotes, but heterozygotes have elevated triglycerides and impaired enzyme activity. J. Biol. Chem. 270: 12518-12525.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12518-12525
    • Coleman, T.1    Seip, R.L.2    Gimble, J.M.3    Lee, D.4    Maeda, N.5    Semenkovich, C.F.6
  • 56
    • 0035650636 scopus 로고    scopus 로고
    • Protection from obesity and insulin resistance in mice overexpressing human apolipoprotein Cl
    • Jong, M. C., P. J. Voshol, M. Muurling, V. E. Dahlmans, J. A. Romijn, H. Pijl, and L. M. Havekes. 2001. Protection from obesity and insulin resistance in mice overexpressing human apolipoprotein Cl. Diabetes. 50: 2779-2785.
    • (2001) Diabetes , vol.50 , pp. 2779-2785
    • Jong, M.C.1    Voshol, P.J.2    Muurling, M.3    Dahlmans, V.E.4    Romijn, J.A.5    Pijl, H.6    Havekes, L.M.7
  • 58
    • 0037155899 scopus 로고    scopus 로고
    • Very low density lipoprotein (VLDL) receptor-deficient mice have reduced lipoprotein lipase activity. Possible causes of hypertriglyceridemia and reduced body mass with VLDL receptor deficiency
    • Yagyu, H., E. P. Lutz, Y. Kako, S. Marks, Y. Hu, S. Y. Choi, A. Bensadoun, and I. J. Goldberg. 2002. Very low density lipoprotein (VLDL) receptor-deficient mice have reduced lipoprotein lipase activity. Possible causes of hypertriglyceridemia and reduced body mass with VLDL receptor deficiency. J. Biol. Chem. 277: 10037-10043.
    • (2002) J. Biol. Chem. , vol.277 , pp. 10037-10043
    • Yagyu, H.1    Lutz, E.P.2    Kako, Y.3    Marks, S.4    Hu, Y.5    Choi, S.Y.6    Bensadoun, A.7    Goldberg, I.J.8
  • 59
    • 0035937846 scopus 로고    scopus 로고
    • Transcytosis of lipoprotein lipase across cultured endothelial cells requires both heparan sulfate proteoglycans and the very low density lipoprotein receptor
    • Obunike, J. C., E. P. Lutz, Z. Li, L. Paka, T. Katopodis, D. K. Strickland, K. F. Kozarsky, S. Pillarisetti, and I. J. Goldberg. 2001. Transcytosis of lipoprotein lipase across cultured endothelial cells requires both heparan sulfate proteoglycans and the very low density lipoprotein receptor. J. Biol. Chem. 276: 8934-8941.
    • (2001) J. Biol. Chem. , vol.276 , pp. 8934-8941
    • Obunike, J.C.1    Lutz, E.P.2    Li, Z.3    Paka, L.4    Katopodis, T.5    Strickland, D.K.6    Kozarsky, K.F.7    Pillarisetti, S.8    Goldberg, I.J.9


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