Advanced mass spectrometry workflows for analyzing disulfide bonds in biologics

Expert Review of Proteomics

Volumn 12, Issue 2, 2015, Pages 115-123

  Wiesner, Jan ^a   Resemann, Anja ^a   Evans, Catherine ^a   Suckau, Detlev ^a   Jabs, Wolfgang ^a  

^a BRUKER DALTONIK GMBH   (Germany)

Author keywords

antibodies; biologics; biosimilar development; blood factors; disulfide bonds; higher order structure analysis; mass spectrometry

Indexed keywords

BIOLOGICAL PRODUCT; BIOSIMILAR AGENT; PROTEIN DERIVATIVE; DISULFIDE; PROTEIN; RECOMBINANT PROTEIN;

ANALYTIC METHOD; ARTICLE; AUTOMATION; DISULFIDE BOND; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PROTEIN CLEAVAGE; PROTEIN STRUCTURE; WORKFLOW; CHEMISTRY; HUMAN; PROCEDURES;

ANIMALIA;

DISULFIDES; HUMANS; MASS SPECTROMETRY; PROTEINS; RECOMBINANT PROTEINS;

EID: 84925343208     PISSN: 14789450     EISSN: 17448387     Source Type: Journal    
DOI: 10.1586/14789450.2015.1018896     Document Type: Article

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