Reversed-Phase Liquid Chromatography In-Line with Negative Ionization Electrospray Mass Spectrometry for the Characterization of the Disulfide-Linkages of an Immunoglobulin Gamma Antibody

Journal of the American Society for Mass Spectrometry

Volumn 17, Issue 11, 2006, Pages 1590-1598

  Chelius, Dirk ^a   Huff Wimer, Mary E ^a   Bondarenko, Pavel V ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBODIES; CHEMICAL BONDS; DIMERS; ENZYME KINETICS; IONIZATION; MASS SPECTROMETRY; MOLECULAR WEIGHT;

DISULFIDE BONDS; DISULFIDE LINKAGES; NEGATIVE IONIZATION ELECTROSPRAY MASS SPECTROMETRY; REVERSED PHASE LIQUID CHROMATOGRAPHY;

LIQUID CHROMATOGRAPHY;

AMINO ACID; ANTIBODY; CYSTEINE; DISULFIDE; IMMUNOGLOBULIN G ANTIBODY; PEPTIDE;

AMINO TERMINAL SEQUENCE; ANALYTIC METHOD; ARTICLE; COVALENT BOND; DISULFIDE BOND; ELECTROSPRAY MASS SPECTROMETRY; ENZYMATIC DEGRADATION; HEAVY CHAIN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION TRAP MASS SPECTROMETRY; LIGHT CHAIN; MASS SPECTROMETRY; PEPTIDE ANALYSIS; PROTEIN ANALYSIS; REVERSED PHASE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; TIME OF FLIGHT MASS SPECTROMETRY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISULFIDES; HUMANS; IMMUNOGLOBULIN GAMMA-CHAINS; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 33750313493     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2006.07.008     Document Type: Article

References (17)

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