메뉴 건너뛰기




Volumn 18, Issue 9, 2014, Pages 773-786

Compositional dynamics of the human intestinal microbiota with aging: Implications for health

Author keywords

aging; Gastrointestinal tract; host health; microbiota

Indexed keywords

PREBIOTIC AGENT; PROBIOTIC AGENT; SYNBIOTIC AGENT; ANTIINFECTIVE AGENT;

EID: 84925284836     PISSN: 12797707     EISSN: 17604788     Source Type: Journal    
DOI: 10.1007/s12603-014-0549-6     Document Type: Article
Times cited : (74)

References (225)
  • 1
    • 0017341656 scopus 로고
    • Microbial ecology of the gastrointestinal tract
    • COI: 1:STN:280:DyaE1c%2FhvVGksw%3D%3D
    • Savage DC. Microbial ecology of the gastrointestinal tract. Ann Rev Microbiol 1977; 31: 107–133.
    • (1977) Ann Rev Microbiol , vol.31 , pp. 107-133
    • Savage, D.C.1
  • 2
    • 20544444045 scopus 로고    scopus 로고
    • Diversity of the human intestinal microbial flora
    • PID: 15831718
    • Eckburg PB, Bik EM, Bernstein CN et al. Diversity of the human intestinal microbial flora. Science 2005; 308: 1635–1638.
    • (2005) Science , vol.308 , pp. 1635-1638
    • Eckburg, P.B.1    Bik, E.M.2    Bernstein, C.N.3
  • 3
    • 33747177087 scopus 로고    scopus 로고
    • Assembly of the human intestinal microbiota
    • PID: 16820245
    • Dethlefsen L, Eckburg PB, Bik EM et al. Assembly of the human intestinal microbiota. Trends Ecol Evol 2006; 21: 517–523.
    • (2006) Trends Ecol Evol , vol.21 , pp. 517-523
    • Dethlefsen, L.1    Eckburg, P.B.2    Bik, E.M.3
  • 4
    • 33645471793 scopus 로고    scopus 로고
    • A microbial world within us
    • COI: 1:CAS:528:DC%2BD28Xjslaktbc%3D, PID: 16553872
    • Zoetendal EG, Vaughan EE, De Vos WM. A microbial world within us. Mol Microbiol 2006; 59: 1639–1650.
    • (2006) Mol Microbiol , vol.59 , pp. 1639-1650
    • Zoetendal, E.G.1    Vaughan, E.E.2    De Vos, W.M.3
  • 5
    • 34547683600 scopus 로고    scopus 로고
    • Diversity of the human gastrointestinal tract microbiota revisited
    • PID: 17686012
    • Rajilić-Stojanović M, Smidt H, De Vos WM. Diversity of the human gastrointestinal tract microbiota revisited. Environ Microbiol 2007; 9: 2125–2136.
    • (2007) Environ Microbiol , vol.9 , pp. 2125-2136
    • Rajilić-Stojanović, M.1    Smidt, H.2    De Vos, W.M.3
  • 6
    • 34447516925 scopus 로고    scopus 로고
    • Evolution of Symbiotic Bacteria in the Distal Human Intestine
    • Xu J, Mahowald MA, Ley RE et al. Evolution of Symbiotic Bacteria in the Distal Human Intestine. PLoS Biol 2007; 5: el56.
    • (2007) PLoS Biol , vol.5
    • Xu, J.1    Mahowald, M.A.2    Ley, R.E.3
  • 7
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • COI: 1:CAS:528:DC%2BC3cXislahsLc%3D, PID: 20203603
    • Qin J, Li R, Raes J et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 2010; 464: 59–65.
    • (2010) Nature , vol.464 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3
  • 8
    • 0037425743 scopus 로고    scopus 로고
    • Gut flora in health and disease
    • PID: 12583961
    • Guarner F, Malagelada J-R. Gut flora in health and disease. Lancet 2003; 361: 512–519.
    • (2003) Lancet , vol.361 , pp. 512-519
    • Guarner, F.1    Malagelada, J.-R.2
  • 9
    • 15544369658 scopus 로고    scopus 로고
    • Host-bacterial mutualism in the human intestine
    • PID: 15790844
    • Bäckhed F, Ley RE, Sonnenburg JL et al. Host-bacterial mutualism in the human intestine. Science 2005; 307: 1915–1920.
    • (2005) Science , vol.307 , pp. 1915-1920
    • Bäckhed, F.1    Ley, R.E.2    Sonnenburg, J.L.3
  • 10
    • 17044370477 scopus 로고    scopus 로고
    • Fermented functional foods based on probiotics and their biogenic metabolites
    • COI: 1:CAS:528:DC%2BD2MXjtlals78%3D, PID: 15831387
    • Stanton C, Ross RP, Fitzgerald GF et al. Fermented functional foods based on probiotics and their biogenic metabolites. Curr Opin Biotechnol 2005; 16: 198–203.
    • (2005) Curr Opin Biotechnol , vol.16 , pp. 198-203
    • Stanton, C.1    Ross, R.P.2    Fitzgerald, G.F.3
  • 11
    • 59949088614 scopus 로고    scopus 로고
    • Effect of molecules secreted by Lactobacillus acidophilus strain La-5 on Escherichia coli 0157: H7 colonization
    • PID: 19088323
    • Medellin-Peña MJ, Griffiths MW. Effect of molecules secreted by Lactobacillus acidophilus strain La-5 on Escherichia coli 0157: H7 colonization. Appl Environ Microbiol 2009; 75: 1165–1172.
    • (2009) Appl Environ Microbiol , vol.75 , pp. 1165-1172
    • Medellin-Peña, M.J.1    Griffiths, M.W.2
  • 12
    • 0030041078 scopus 로고    scopus 로고
    • Econutrition and health maintenance—a new concept to prevent GI inflammation, ulceration and sepsis
    • COI: 1:STN:280:DC%2BD28vitVyktg%3D%3D, PID: 16843987
    • Bengmark S. Econutrition and health maintenance—a new concept to prevent GI inflammation, ulceration and sepsis. Clin Nutr 1996; 15: 1–10.
    • (1996) Clin Nutr , vol.15 , pp. 1-10
    • Bengmark, S.1
  • 13
    • 84975175057 scopus 로고    scopus 로고
    • Microbial induction of immunity, inflammation, and cancer
    • Greer JB, O’Keefe SJ. Microbial induction of immunity, inflammation, and cancer. Front Physiol 2010; 1: 168.
    • (2010) Front Physiol , vol.1 , pp. 168
    • Greer, J.B.1    O’Keefe, S.J.2
  • 14
    • 0031684010 scopus 로고    scopus 로고
    • Temperature gradient gel electrophoresis analysis of 16S rRNA from human fecal samples reveals stable and host-specific communities of active bacteria
    • COI: 1:CAS:528:DyaK1cXms1entLY%3D, PID: 9758810
    • Zoetendal EG, Akkermans ADL, De Vos WM. Temperature gradient gel electrophoresis analysis of 16S rRNA from human fecal samples reveals stable and host-specific communities of active bacteria. Appl Environ Microbiol 1998; 64: 3854–3859.
    • (1998) Appl Environ Microbiol , vol.64 , pp. 3854-3859
    • Zoetendal, E.G.1    Akkermans, A.D.L.2    De Vos, W.M.3
  • 15
    • 34547129847 scopus 로고    scopus 로고
    • Development of the human infant intestinal microbiota
    • Palmer C, Bik EM, DiGiulio DB et al. Development of the human infant intestinal microbiota. PLoS Biol 2007; 5: el77.
    • (2007) PLoS Biol , vol.5
    • Palmer, C.1    Bik, E.M.2    DiGiulio, D.B.3
  • 16
    • 33947186284 scopus 로고    scopus 로고
    • Metabolic diversity of the intestinal microbiota: implications for health and disease
    • COI: 1:CAS:528:DC%2BD2sXisVygsbk%3D, PID: 17311972
    • Blaut M, Clavel T. Metabolic diversity of the intestinal microbiota: implications for health and disease. J Nutr 2007; 137: 751S–755S.
    • (2007) J Nutr , vol.137 , pp. 751S-755S
    • Blaut, M.1    Clavel, T.2
  • 17
    • 33748415364 scopus 로고    scopus 로고
    • Factors influencing the composition of the intestinal microbiota in early infancy
    • PID: 16882802
    • Penders J, Thijs C, Vink C et al. Factors influencing the composition of the intestinal microbiota in early infancy. Pediatrics 2006; 118: 511–521.
    • (2006) Pediatrics , vol.118 , pp. 511-521
    • Penders, J.1    Thijs, C.2    Vink, C.3
  • 18
    • 77955386857 scopus 로고    scopus 로고
    • Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns
    • PID: 20566857
    • Dominguez-Bello MG, Costello EK, Contreras M et al. Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Proc Natl Acad Sci U S A 2010; 107: 11971–11975.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 11971-11975
    • Dominguez-Bello, M.G.1    Costello, E.K.2    Contreras, M.3
  • 19
    • 0032974177 scopus 로고    scopus 로고
    • Fecal microflora in healthy infants born by different methods of delivery: permanent changes in intestinal flora after cesarean delivery
    • Grölund M-M, Lehtonen O-P, Eerola E et al. Fecal microflora in healthy infants born by different methods of delivery: permanent changes in intestinal flora after cesarean delivery. J Ped Gastroenterol Nutr 1999; 28: 19–25.
    • (1999) J Ped Gastroenterol Nutr , vol.28 , pp. 19-25
    • Grölund, M.-M.1    Lehtonen, O.-P.2    Eerola, E.3
  • 20
    • 0036135946 scopus 로고    scopus 로고
    • Molecular monitoring of succession of bacterial communities in human neonates
    • COI: 1:CAS:528:DC%2BD38Xjt1Wntw%3D%3D, PID: 11772630
    • Favier CF, Vaughan EE, De Vos WM et al. Molecular monitoring of succession of bacterial communities in human neonates. Appl Environ Microbiol 2002; 68: 219–226.
    • (2002) Appl Environ Microbiol , vol.68 , pp. 219-226
    • Favier, C.F.1    Vaughan, E.E.2    De Vos, W.M.3
  • 21
    • 77957075815 scopus 로고    scopus 로고
    • Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
    • PID: 20679230
    • De Filippo C, Cavalieri D, Di Paola M et al. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci U S A 2010; 107: 14691–14696.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 14691-14696
    • De Filippo, C.1    Cavalieri, D.2    Di Paola, M.3
  • 23
    • 33645865842 scopus 로고    scopus 로고
    • Identification of dominant bacteria in feces and colonic mucosa from healthy Spanish adults by culturing and by 16S rDNA sequence analysis
    • PID: 16614998
    • Delgado S, Suárez A, Mayo B. Identification of dominant bacteria in feces and colonic mucosa from healthy Spanish adults by culturing and by 16S rDNA sequence analysis. Dig Dis Sci 2006; 51: 744–751.
    • (2006) Dig Dis Sci , vol.51 , pp. 744-751
    • Delgado, S.1    Suárez, A.2    Mayo, B.3
  • 24
    • 46249085739 scopus 로고    scopus 로고
    • Evolution of mammals and their gut microbes
    • COI: 1:CAS:528:DC%2BD1cXnt1Oju7o%3D, PID: 18497261
    • Ley RE, Hamady M, Lozupone C et al. Evolution of mammals and their gut microbes. Science 2008; 320: 1647–1651.
    • (2008) Science , vol.320 , pp. 1647-1651
    • Ley, R.E.1    Hamady, M.2    Lozupone, C.3
  • 25
    • 77949393654 scopus 로고    scopus 로고
    • Gut microbiota in human adults with type 2 diabetes differs from non-diabetic adults
    • PID: 20140211
    • Larsen N, Vogensen FK, van den Berg FWJ et al. Gut microbiota in human adults with type 2 diabetes differs from non-diabetic adults. PLoS One 2010; 5: e9085.
    • (2010) PLoS One , vol.5
    • Larsen, N.1    Vogensen, F.K.2    van den Berg, F.W.J.3
  • 26
    • 56849106496 scopus 로고    scopus 로고
    • The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing
    • PID: 19018661
    • Dethlefsen L, Huse S, Sogin ML et al. The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. PLoS Biol 2008; 6: e280.
    • (2008) PLoS Biol , vol.6
    • Dethlefsen, L.1    Huse, S.2    Sogin, M.L.3
  • 27
    • 0017253248 scopus 로고
    • Human fecal flora: variation in bacterial composition within individuals and a possible effect of emotional stress
    • COI: 1:STN:280:DyaE283jtVantw%3D%3D, PID: 938032
    • Holdeman LV, Good IJ, Moore WE. Human fecal flora: variation in bacterial composition within individuals and a possible effect of emotional stress. Appl Environ Microbiol 1976; 31: 359–375.
    • (1976) Appl Environ Microbiol , vol.31 , pp. 359-375
    • Holdeman, L.V.1    Good, I.J.2    Moore, W.E.3
  • 28
    • 30944438671 scopus 로고    scopus 로고
    • Malnutrition and ageing
    • COI: 1:STN:280:DC%2BD28%2FhtFSltw%3D%3D, PID: 16397072
    • Hickson M. Malnutrition and ageing. Postgrad Med J 2006; 82: 2–8.
    • (2006) Postgrad Med J , vol.82 , pp. 2-8
    • Hickson, M.1
  • 29
    • 0029935217 scopus 로고    scopus 로고
    • Age related changes in gut physiology and nutritional status
    • COI: 1:STN:280:DyaK283ks12hsw%3D%3D, PID: 8675079
    • Lovat LB. Age related changes in gut physiology and nutritional status. Gut 1996; 38: 306–309.
    • (1996) Gut , vol.38 , pp. 306-309
    • Lovat, L.B.1
  • 30
    • 0035079331 scopus 로고    scopus 로고
    • Differences in the distribution of bifidobacterial and enterobacterial species in human faecal microflora of three different (children, adults, elderly) age groups
    • Gavini F, Cayuela C, Antoine J-M et al. Differences in the distribution of bifidobacterial and enterobacterial species in human faecal microflora of three different (children, adults, elderly) age groups. Microb Ecol Health Dis 2001; 13: 40–45.
    • (2001) Microb Ecol Health Dis , vol.13 , pp. 40-45
    • Gavini, F.1    Cayuela, C.2    Antoine, J.-M.3
  • 31
    • 79952757721 scopus 로고    scopus 로고
    • Composition, variability, and temporal stability of the intestinal microbiota of the elderly
    • COI: 1:CAS:528:DC%2BC3MXjvVCkurg%3D, PID: 20571116
    • Claesson MJ, Cusack S, O’Sullivan O et al. Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proc Natl Acad Sci U S A 2011; 108:4586–4591.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4586-4591
    • Claesson, M.J.1    Cusack, S.2    O’Sullivan, O.3
  • 32
    • 34247384151 scopus 로고    scopus 로고
    • Intestinal bacteria and ageing
    • COI: 1:CAS:528:DC%2BD2sXmslKgtbc%3D, PID: 17448153
    • Woodmansey EJ. Intestinal bacteria and ageing. J Appl Microbiol 2007; 102: 1178–1186.
    • (2007) J Appl Microbiol , vol.102 , pp. 1178-1186
    • Woodmansey, E.J.1
  • 33
    • 0036241355 scopus 로고    scopus 로고
    • Changes in predominant bacterial populations in human faeces with age and with Clostridium difficile infection
    • COI: 1:STN:280:DC%2BD383lt1Khug%3D%3D, PID: 11990498
    • Hopkins MJ, Macfarlane GT. Changes in predominant bacterial populations in human faeces with age and with Clostridium difficile infection. J Med Microbiol 2002;51:448–454.
    • (2002) J Med Microbiol , vol.51 , pp. 448-454
    • Hopkins, M.J.1    Macfarlane, G.T.2
  • 34
    • 84874593878 scopus 로고    scopus 로고
    • Metabolic Signatures of Extreme Longevity in Northern Italian Centenarians Reveal a Complex Remodeling of Lipids, Amino Acids, and Gut Microbiota Metabolism
    • COI: 1:CAS:528:DC%2BC3sXktlSqsLk%3D, PID: 23483888
    • Collino S, Montoliu I, Martin F-PJ et al. Metabolic Signatures of Extreme Longevity in Northern Italian Centenarians Reveal a Complex Remodeling of Lipids, Amino Acids, and Gut Microbiota Metabolism. PLoS One 2013; 8: e56564.
    • (2013) PLoS One , vol.8
    • Collino, S.1    Montoliu, I.2    Martin, F.-P.3
  • 35
    • 2942592005 scopus 로고    scopus 로고
    • Characterization of bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by using realtime PCR and effects of antibiotic treatment on the fecal microbiota
    • COI: 1:CAS:528:DC%2BD2cXltFCitbg%3D, PID: 15184159
    • Bartosch S, Fite A, Macfarlane GT et al. Characterization of bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by using realtime PCR and effects of antibiotic treatment on the fecal microbiota. Appl Environ Microbiol 2004; 70: 3575–3581.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 3575-3581
    • Bartosch, S.1    Fite, A.2    Macfarlane, G.T.3
  • 36
    • 77955602581 scopus 로고    scopus 로고
    • Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians
    • Biagi E, Nylund L, Candela M et al. Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians. PLoS One 2010; 5: el0667.
    • (2010) PLoS One , vol.5 , pp. el0667
    • Biagi, E.1    Nylund, L.2    Candela, M.3
  • 37
    • 84864722033 scopus 로고    scopus 로고
    • Gut microbiota composition correlates with diet and health in the elderly
    • COI: 1:CAS:528:DC%2BC38XhtFKiur%2FP, PID: 22797518
    • Claesson MJ, Jeffery IB, Conde S et al. Gut microbiota composition correlates with diet and health in the elderly. Nature 2012; 488: 178–184.
    • (2012) Nature , vol.488 , pp. 178-184
    • Claesson, M.J.1    Jeffery, I.B.2    Conde, S.3
  • 38
    • 77949285392 scopus 로고    scopus 로고
    • Human intestinal microbiota and healthy ageing
    • PID: 19874918
    • Tiihonen K, Ouwehand AC, Rautonen N. Human intestinal microbiota and healthy ageing. Ageing Res Rev 2010; 9: 107–116.
    • (2010) Ageing Res Rev , vol.9 , pp. 107-116
    • Tiihonen, K.1    Ouwehand, A.C.2    Rautonen, N.3
  • 39
    • 0035124967 scopus 로고    scopus 로고
    • Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles
    • COI: 1:STN:280:DC%2BD3M7is1Wgtg%3D%3D, PID: 11156640
    • Hopkins MJ, Sharp R, Macfarlane GT. Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles. Gut 2001; 48: 198–205.
    • (2001) Gut , vol.48 , pp. 198-205
    • Hopkins, M.J.1    Sharp, R.2    Macfarlane, G.T.3
  • 40
    • 67651151152 scopus 로고    scopus 로고
    • The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age
    • COI: 1:CAS:528:DC%2BD1MXnsFSrtr4%3D, PID: 19508720
    • Mariat D, Firmesse O, Levenez F et al. The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age. BMC Microbiol 2009; 9: 123.
    • (2009) BMC Microbiol , vol.9 , pp. 123
    • Mariat, D.1    Firmesse, O.2    Levenez, F.3
  • 41
    • 53149150212 scopus 로고    scopus 로고
    • The effect of ageing with and without non-steroidal anti-inflammatory drugs on gastrointestinal microbiology and immunology
    • COI: 1:CAS:528:DC%2BD1cXot1aqsbw%3D, PID: 18279548
    • Tiihonen K, Tynkkynen S, Ouwehand A et al. The effect of ageing with and without non-steroidal anti-inflammatory drugs on gastrointestinal microbiology and immunology. Br J Nutr 2008; 100: 130–137.
    • (2008) Br J Nutr , vol.100 , pp. 130-137
    • Tiihonen, K.1    Tynkkynen, S.2    Ouwehand, A.3
  • 42
    • 84857434378 scopus 로고    scopus 로고
    • Clostridium difficile carriage in elderly subjects and associated changes in the intestinal microbiota
    • COI: 1:CAS:528:DC%2BC38Xls1eqtLY%3D, PID: 22162545
    • Rea MC, O’Sullivan O, Shanahan F et al. Clostridium difficile carriage in elderly subjects and associated changes in the intestinal microbiota. J Clin Microbiol 2012; 50: 867–875.
    • (2012) J Clin Microbiol , vol.50 , pp. 867-875
    • Rea, M.C.1    O’Sullivan, O.2    Shanahan, F.3
  • 43
    • 0034761174 scopus 로고    scopus 로고
    • Differences in composition and mucosal adhesion of bifidobacteria isolated from healthy adults and healthy seniors
    • COI: 1:CAS:528:DC%2BD3MXosVGrsrg%3D, PID: 11688800
    • He F, Ouwehand AC, Isolauri E et al. Differences in composition and mucosal adhesion of bifidobacteria isolated from healthy adults and healthy seniors. Curr Microbiol 2001; 43: 351–354.
    • (2001) Curr Microbiol , vol.43 , pp. 351-354
    • He, F.1    Ouwehand, A.C.2    Isolauri, E.3
  • 44
    • 75549083189 scopus 로고    scopus 로고
    • The effect of age and non-steroidal anti-inflammatory drugs on human intestinal microbiota composition
    • PID: 19703328
    • Mäkivuokko H, Tiihonen K, Tynkkynen S et al. The effect of age and non-steroidal anti-inflammatory drugs on human intestinal microbiota composition. Br J Nutr 2010; 103: 227–234.
    • (2010) Br J Nutr , vol.103 , pp. 227-234
    • Mäkivuokko, H.1    Tiihonen, K.2    Tynkkynen, S.3
  • 45
    • 33144460422 scopus 로고    scopus 로고
    • Differences in fecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study
    • COI: 1:CAS:528:DC%2BD28Xhs1Ghs7Y%3D, PID: 16461645
    • Mueller S, Saunier K, Hanisch C et al. Differences in fecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study. Appl Environ Microbiol 2006; 72: 1027–1033.
    • (2006) Appl Environ Microbiol , vol.72 , pp. 1027-1033
    • Mueller, S.1    Saunier, K.2    Hanisch, C.3
  • 46
    • 0042471955 scopus 로고    scopus 로고
    • Molecular analysis of fecal microbiota in elderly individuals using 16S rDNA library and T-RFLP
    • COI: 1:CAS:528:DC%2BD3sXnslKhs78%3D, PID: 14524616
    • Hayashi H, Sakamoto M, Kitahara M et al. Molecular analysis of fecal microbiota in elderly individuals using 16S rDNA library and T-RFLP. Microbiol Immunol 2003; 47:557–570.
    • (2003) Microbiol Immunol , vol.47 , pp. 557-570
    • Hayashi, H.1    Sakamoto, M.2    Kitahara, M.3
  • 47
    • 66049127999 scopus 로고    scopus 로고
    • Combined PCR-DGGE fingerprinting and quantitative-PCR indicates shifts in fecal population sizes and diversity of Bacteroides, bifidobacteria and Clostridium cluster IV in institutionalized elderly
    • COI: 1:CAS:528:DC%2BD1MXms1yqu78%3D, PID: 19376217
    • Zwielehner J, Liszt K, Handschur M et al. Combined PCR-DGGE fingerprinting and quantitative-PCR indicates shifts in fecal population sizes and diversity of Bacteroides, bifidobacteria and Clostridium cluster IV in institutionalized elderly. Exp Gerontol 2009; 44: 440–446.
    • (2009) Exp Gerontol , vol.44 , pp. 440-446
    • Zwielehner, J.1    Liszt, K.2    Handschur, M.3
  • 48
    • 0024510314 scopus 로고
    • Comparison of fecal microflora of elderly persons in rural and urban areas of Japan
    • COI: 1:STN:280:DyaL1MzjsVegtA%3D%3D, PID: 2547333
    • Benno Y, Endo K, Mizutani T et al. Comparison of fecal microflora of elderly persons in rural and urban areas of Japan. Appl Environ Microbiol 1989; 55: 1100–1105.
    • (1989) Appl Environ Microbiol , vol.55 , pp. 1100-1105
    • Benno, Y.1    Endo, K.2    Mizutani, T.3
  • 49
    • 30944466824 scopus 로고    scopus 로고
    • Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach
    • COI: 1:CAS:528:DC%2BD28XhsFaqsL8%3D, PID: 16188921
    • Manichanh C, Rigottier-Gois L, Bonnaud E et al. Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach. Gut 2006; 55: 205–211.
    • (2006) Gut , vol.55 , pp. 205-211
    • Manichanh, C.1    Rigottier-Gois, L.2    Bonnaud, E.3
  • 50
    • 70349488325 scopus 로고    scopus 로고
    • Low counts of Faecalibacterium prausnitzii in colitis microbiota
    • COI: 1:STN:280:DC%2BD1MvpsFaisQ%3D%3D, PID: 19235886
    • Sokol H, Seksik P, Furet JP et al. Low counts of Faecalibacterium prausnitzii in colitis microbiota. Inflamm Bowel Dis 2009; 15: 1183–1189.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 1183-1189
    • Sokol, H.1    Seksik, P.2    Furet, J.P.3
  • 51
    • 77955647582 scopus 로고    scopus 로고
    • Gut microbiota in health and disease
    • COI: 1:CAS:528:DC%2BC3cXhtVyku7rM, PID: 20664075
    • Sekirov I, Russell SL, Antunes LCM et al. Gut microbiota in health and disease. Physiol Rev 2010; 90: 859–904.
    • (2010) Physiol Rev , vol.90 , pp. 859-904
    • Sekirov, I.1    Russell, S.L.2    Antunes, L.C.M.3
  • 52
    • 33644928317 scopus 로고    scopus 로고
    • The probiotic bacterium Lactobacillus casei induces activation of the gut mucosal immune system through innate immunity
    • COI: 1:CAS:528:DC%2BD28Xhs1Gmsbg%3D, PID: 16467329
    • Galdeano CM, Perdigon G. The probiotic bacterium Lactobacillus casei induces activation of the gut mucosal immune system through innate immunity. Clin Vaccine Immunol 2006; 13: 219–226.
    • (2006) Clin Vaccine Immunol , vol.13 , pp. 219-226
    • Galdeano, C.M.1    Perdigon, G.2
  • 53
    • 47349131536 scopus 로고    scopus 로고
    • Interaction of probiotic Lactobacillus and Bifidobacterium strains with human intestinal epithelial cells: Adhesion properties, competition against enteropathogens and modulation of IL-8 production
    • COI: 1:CAS:528:DC%2BD1cXptVKrt7g%3D
    • Candela M, Perna F, Carnevali P et al. Interaction of probiotic Lactobacillus and Bifidobacterium strains with human intestinal epithelial cells: Adhesion properties, competition against enteropathogens and modulation of IL-8 production. Intl J Food Microbiol 2008; 125: 286–292.
    • (2008) Intl J Food Microbiol , vol.125 , pp. 286-292
    • Candela, M.1    Perna, F.2    Carnevali, P.3
  • 54
    • 78650408264 scopus 로고    scopus 로고
    • Diet, gut microbiota and immune responses
    • Maslowski KM, Mackay CR. Diet, gut microbiota and immune responses. Nature Immunol 2010; 12: 5–9.
    • (2010) Nature Immunol , vol.12 , pp. 5-9
    • Maslowski, K.M.1    Mackay, C.R.2
  • 55
    • 79251584066 scopus 로고    scopus 로고
    • Bifidobacteria can protect from enteropathogenic infection through production of acetate
    • COI: 1:CAS:528:DC%2BC3MXhtFShtLs%3D, PID: 21270894
    • Fukuda S, Toh H, Hase K et al. Bifidobacteria can protect from enteropathogenic infection through production of acetate. Nature 2011; 469: 543–547.
    • (2011) Nature , vol.469 , pp. 543-547
    • Fukuda, S.1    Toh, H.2    Hase, K.3
  • 56
    • 70350566110 scopus 로고    scopus 로고
    • The putative role of the intestinal microbiota in the irritable bowel syndrome
    • COI: 1:STN:280:DC%2BD1MjksVaksQ%3D%3D, PID: 19740713
    • Collins SM, Denou E, Verdu EF et al. The putative role of the intestinal microbiota in the irritable bowel syndrome. Dig Liver Dis 2009; 41: 850–853.
    • (2009) Dig Liver Dis , vol.41 , pp. 850-853
    • Collins, S.M.1    Denou, E.2    Verdu, E.F.3
  • 57
    • 77956825557 scopus 로고    scopus 로고
    • Contribution of gut bacteria to liver pathobiology
    • Son G, Kremer M, Hines IN. Contribution of gut bacteria to liver pathobiology. Gastroenterol Res Pract 2010; 2010: Article ID: 453563.
    • (2010) Gastroenterol Res Pract
    • Son, G.1    Kremer, M.2    Hines, I.N.3
  • 58
    • 35348857386 scopus 로고    scopus 로고
    • Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
    • COI: 1:CAS:528:DC%2BD2sXpvVGjsbg%3D, PID: 17699621
    • Frank DN, St Amand AL, Feldman RA et al. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A 2007; 104: 13780–13785.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 13780-13785
    • Frank, D.N.1    St Amand, A.L.2    Feldman, R.A.3
  • 59
    • 0942301264 scopus 로고    scopus 로고
    • Microbial degradation products influence colon cancer risk: the butyrate controversy
    • COI: 1:CAS:528:DC%2BD2cXhtFKlsbk%3D, PID: 14747692
    • Lupton JR. Microbial degradation products influence colon cancer risk: the butyrate controversy. J Nutr 2004; 134: 479–482.
    • (2004) J Nutr , vol.134 , pp. 479-482
    • Lupton, J.R.1
  • 60
    • 67650299380 scopus 로고    scopus 로고
    • Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility
    • PID: 19551144
    • Uronis JM, Mühlbauer M, Herfarth HH et al. Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility. PLoS One 2009; 4: e6026.
    • (2009) PLoS One , vol.4
    • Uronis, J.M.1    Mühlbauer, M.2    Herfarth, H.H.3
  • 61
    • 79959201412 scopus 로고    scopus 로고
    • Human nutrition, the gut microbiome and the immune system
    • COI: 1:CAS:528:DC%2BC3MXnsFOqsb4%3D, PID: 21677749
    • Kau AL, Ahem PP, Griffin NW et al. Human nutrition, the gut microbiome and the immune system. Nature 2011; 474: 327–336.
    • (2011) Nature , vol.474 , pp. 327-336
    • Kau, A.L.1    Ahem, P.P.2    Griffin, N.W.3
  • 62
    • 84873875156 scopus 로고    scopus 로고
    • Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor
    • COI: 1:CAS:528:DC%2BC3sXhsFGrsL8%3D, PID: 23363771
    • Smith MI, Yatsunenko T, Manary MJ et al. Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor. Science 2013; 339: 548–554.
    • (2013) Science , vol.339 , pp. 548-554
    • Smith, M.I.1    Yatsunenko, T.2    Manary, M.J.3
  • 63
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • COI: 1:CAS:528:DC%2BD28XhtlemtLvM, PID: 17183309
    • Ley RE, Turnbaugh PJ, Klein S et al. Microbial ecology: human gut microbes associated with obesity. Nature 2006; 444: 1022–1023.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3
  • 64
    • 58749112734 scopus 로고    scopus 로고
    • A core gut microbiome in obese and lean twins
    • PID: 19043404
    • Turnbaugh PJ, Hamady M, Yatsunenko T et al. A core gut microbiome in obese and lean twins. Nature 2008; 457: 480–484.
    • (2008) Nature , vol.457 , pp. 480-484
    • Turnbaugh, P.J.1    Hamady, M.2    Yatsunenko, T.3
  • 65
    • 0032829725 scopus 로고    scopus 로고
    • Functional bowel disorders and functional abdominal pain
    • PID: 10457044
    • Thompson WG, Longstreth GF, Drossman DA et al. Functional bowel disorders and functional abdominal pain. Gut 1999; 45:II43–II47.
    • (1999) Gut , vol.45 , pp. II43-II47
    • Thompson, W.G.1    Longstreth, G.F.2    Drossman, D.A.3
  • 66
    • 69749085909 scopus 로고    scopus 로고
    • Irritable bowel syndrome in the elderly: An overlooked problem?
    • COI: 1:STN:280:DC%2BD1Mnhs1Oqsw%3D%3D, PID: 19411198
    • Agrawal A, Khan M, Whorwell P. Irritable bowel syndrome in the elderly: An overlooked problem? Dig Liver Dis 2009; 41: 721–724.
    • (2009) Dig Liver Dis , vol.41 , pp. 721-724
    • Agrawal, A.1    Khan, M.2    Whorwell, P.3
  • 67
    • 0023150160 scopus 로고
    • Instability in the faecal flora of a patient suffering from food-related irritable bowel syndrome
    • COI: 1:STN:280:DyaL2s7ktFWitQ%3D%3D, PID: 3820268
    • Bradley HK, Wyatt GM, Bayliss CE et al. Instability in the faecal flora of a patient suffering from food-related irritable bowel syndrome. J Med Microbiol 1987; 23: 29–32.
    • (1987) J Med Microbiol , vol.23 , pp. 29-32
    • Bradley, H.K.1    Wyatt, G.M.2    Bayliss, C.E.3
  • 68
    • 0036083346 scopus 로고    scopus 로고
    • Activation of the mucosal immune system in irritable bowel syndrome
    • Chadwick VS, Chen W, Shu D et al. Activation of the mucosal immune system in irritable bowel syndrome. Gastroenterol 2002; 122: 1778–1783.
    • (2002) Gastroenterol , vol.122 , pp. 1778-1783
    • Chadwick, V.S.1    Chen, W.2    Shu, D.3
  • 69
    • 0036709729 scopus 로고    scopus 로고
    • A review of the role of the gut microflora in irritable bowel syndrome and the effects of probiotics
    • COI: 1:CAS:528:DC%2BD38Xot1yrsLg%3D, PID: 12215182
    • Madden JAJ, Hunter JO. A review of the role of the gut microflora in irritable bowel syndrome and the effects of probiotics. Br J Nutr 2002; 88: s67–s72.
    • (2002) Br J Nutr , vol.88 , pp. s67-s72
    • Madden, J.A.J.1    Hunter, J.O.2
  • 70
    • 12844273701 scopus 로고    scopus 로고
    • Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome—a longitudinal study in IBS and control subjects
    • Mättö J, Maunuksela L, Kajander K et al. Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome—a longitudinal study in IBS and control subjects. FEMS Immunol Med Microbiol 2006; 43: 213–222.
    • (2006) FEMS Immunol Med Microbiol , vol.43 , pp. 213-222
    • Mättö, J.1    Maunuksela, L.2    Kajander, K.3
  • 71
    • 84861578319 scopus 로고    scopus 로고
    • An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota
    • PID: 22180058
    • Jeffery IB, O’Toole PW, Öhman L et al. An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota. Gut 2012; 61: 997–1006.
    • (2012) Gut , vol.61 , pp. 997-1006
    • Jeffery, I.B.1    O’Toole, P.W.2    Öhman, L.3
  • 72
    • 44449127071 scopus 로고    scopus 로고
    • Inflammatory bowel disease of the elderly: a wake-up call
    • Katz S, Feldstein R. Inflammatory bowel disease of the elderly: a wake-up call. Gastroenterol Hepatol 2008; 4: 337–347.
    • (2008) Gastroenterol Hepatol , vol.4 , pp. 337-347
    • Katz, S.1    Feldstein, R.2
  • 73
    • 67649678843 scopus 로고    scopus 로고
    • Inflammatory bowel disease in the elderly is associated with worse outcomes: a national study of hospitalizations
    • PID: 18668678
    • Ananthakrishnan AN, McGinley EL, Binion DG. Inflammatory bowel disease in the elderly is associated with worse outcomes: a national study of hospitalizations. Inflamm Bowel Dis 2009; 15: 182–189.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 182-189
    • Ananthakrishnan, A.N.1    McGinley, E.L.2    Binion, D.G.3
  • 75
    • 46749119859 scopus 로고    scopus 로고
    • Molecular analysis of the gut microbiota of identical twins with Crohn’s disease
    • COI: 1:CAS:528:DC%2BD1cXpsFyjtrg%3D, PID: 18401439
    • Dicksved J, Halfvarson J, Rosenquist M et al. Molecular analysis of the gut microbiota of identical twins with Crohn’s disease. ISME J 2008; 2: 716–727.
    • (2008) ISME J , vol.2 , pp. 716-727
    • Dicksved, J.1    Halfvarson, J.2    Rosenquist, M.3
  • 76
    • 2942654600 scopus 로고    scopus 로고
    • Chemotaxonomic analysis of bacterial populations colonizing the rectal mucosa in patients with ulcerative colitis
    • PID: 15227614
    • Macfarlane S, Furrie E, Cummings JH et al. Chemotaxonomic analysis of bacterial populations colonizing the rectal mucosa in patients with ulcerative colitis. Clin Infect Dis 2004; 38: 1690–1699.
    • (2004) Clin Infect Dis , vol.38 , pp. 1690-1699
    • Macfarlane, S.1    Furrie, E.2    Cummings, J.H.3
  • 77
    • 4043089351 scopus 로고    scopus 로고
    • Enteric infection in relapse of inflammatory bowel disease: importance of microbiological examination of stool
    • PID: 15256979
    • Mylonaki M, Langmead L, Pantes A et al. Enteric infection in relapse of inflammatory bowel disease: importance of microbiological examination of stool. Eur J Gastroenterol Hepatol 2004; 16: 775–778.
    • (2004) Eur J Gastroenterol Hepatol , vol.16 , pp. 775-778
    • Mylonaki, M.1    Langmead, L.2    Pantes, A.3
  • 78
    • 55449090398 scopus 로고    scopus 로고
    • Antibiotic-associated diarrhea: epidemiology, trends and treatment
    • PID: 18811240
    • McFarland LV. Antibiotic-associated diarrhea: epidemiology, trends and treatment. Future Microbiol 2008; 3: 563–578.
    • (2008) Future Microbiol , vol.3 , pp. 563-578
    • McFarland, L.V.1
  • 79
    • 0034057346 scopus 로고    scopus 로고
    • Clostridium difficile-associated diarrhea-The new scourge of the health care facility
    • COI: 1:STN:280:DC%2BD2sjms1Wktg%3D%3D, PID: 18159261
    • Conly JM. Clostridium difficile-associated diarrhea-The new scourge of the health care facility. Can J Infect Dis 2000; 11: 25–27.
    • (2000) Can J Infect Dis , vol.11 , pp. 25-27
    • Conly, J.M.1
  • 80
    • 0034220008 scopus 로고    scopus 로고
    • The rise of Clostridium difficile: the effect of length of stay, patient age and antibiotic use
    • COI: 1:STN:280:DC%2BD3czpslWhsg%3D%3D, PID: 10896804
    • Shek FW, Stacey BS, Rendell J et al. The rise of Clostridium difficile: the effect of length of stay, patient age and antibiotic use. J Hosp Infect 2000; 45: 235–237.
    • (2000) J Hosp Infect , vol.45 , pp. 235-237
    • Shek, F.W.1    Stacey, B.S.2    Rendell, J.3
  • 81
    • 51849124742 scopus 로고    scopus 로고
    • Rising economic impact of Clostridium difficile-associated disease in adult hospitalized patient population
    • COI: 1:CAS:528:DC%2BD1cXovVSms70%3D, PID: 18643746
    • Song X, Bartlett JG, Speck K et al. Rising economic impact of Clostridium difficile-associated disease in adult hospitalized patient population. Infect Control Hosp Epidemiol 2008; 29: 823–828.
    • (2008) Infect Control Hosp Epidemiol , vol.29 , pp. 823-828
    • Song, X.1    Bartlett, J.G.2    Speck, K.3
  • 82
    • 70649107673 scopus 로고    scopus 로고
    • European Society of Clinical Microbiology and Infectious Diseases (ESCMID): treatment guidance document for Clostridium difficile infection (CDI)
    • COI: 1:STN:280:DC%2BD1Mjns1Gntw%3D%3D, PID: 19929973
    • Bauer MP, Kuijper EJ, Van Dissel JT. European Society of Clinical Microbiology and Infectious Diseases (ESCMID): treatment guidance document for Clostridium difficile infection (CDI). Clin Microbiol Infect 2009; 15: 1067–1079.
    • (2009) Clin Microbiol Infect , vol.15 , pp. 1067-1079
    • Bauer, M.P.1    Kuijper, E.J.2    Van Dissel, J.T.3
  • 83
    • 78049332872 scopus 로고    scopus 로고
    • Colorectal cancer epidemiology: incidence, mortality, survival, and risk factors
    • PID: 21037809
    • Haggar FA, Boushey RP. Colorectal cancer epidemiology: incidence, mortality, survival, and risk factors. Clin Colon Rectal Surg 2009; 22: 191–197.
    • (2009) Clin Colon Rectal Surg , vol.22 , pp. 191-197
    • Haggar, F.A.1    Boushey, R.P.2
  • 84
    • 80051618932 scopus 로고    scopus 로고
    • Impact of age on outcome after colorectal cancer surgery in the elderly-a developing country perspective
    • Khan MR, Bari H, Zafar SN et al. Impact of age on outcome after colorectal cancer surgery in the elderly-a developing country perspective. BMC Surgery 2011; 11: 11–17.
    • (2011) BMC Surgery , vol.11 , pp. 11-17
    • Khan, M.R.1    Bari, H.2    Zafar, S.N.3
  • 85
    • 77951081783 scopus 로고    scopus 로고
    • Management of colorectal cancer in the elderly
    • Mongan J, Kalady MF, Peppone L et al. Management of colorectal cancer in the elderly. Clin Geriatr 2010; 18: 30–40.
    • (2010) Clin Geriatr , vol.18 , pp. 30-40
    • Mongan, J.1    Kalady, M.F.2    Peppone, L.3
  • 86
    • 1442310994 scopus 로고    scopus 로고
    • Management of Colorectal Cancer in Elderly Patients
    • PID: 14960128
    • Matasar MJ, Sundararajan V, Grann VR et al. Management of Colorectal Cancer in Elderly Patients. Drugs Aging 2004; 21: 113–133.
    • (2004) Drugs Aging , vol.21 , pp. 113-133
    • Matasar, M.J.1    Sundararajan, V.2    Grann, V.R.3
  • 87
    • 0029084396 scopus 로고
    • Intestinal floras of populations that have a high risk of colon cancer
    • COI: 1:CAS:528:DyaK2MXnvVyis7s%3D, PID: 7574628
    • Moore WE, Moore LH. Intestinal floras of populations that have a high risk of colon cancer. Appl Environ Microbiol 1995; 61: 3202–3207.
    • (1995) Appl Environ Microbiol , vol.61 , pp. 3202-3207
    • Moore, W.E.1    Moore, L.H.2
  • 88
    • 0025166175 scopus 로고
    • The fecapentaenes, potent mutagens from human feces
    • COI: 1:CAS:528:DyaK3cXlt1Oksb4%3D, PID: 2133089
    • Kingston DGI, Van Tassell RL, Wilkins TD. The fecapentaenes, potent mutagens from human feces. Chem Res Toxicol 1990; 3: 391–400.
    • (1990) Chem Res Toxicol , vol.3 , pp. 391-400
    • Kingston, D.G.I.1    Van Tassell, R.L.2    Wilkins, T.D.3
  • 89
    • 38549107462 scopus 로고    scopus 로고
    • Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis
    • COI: 1:CAS:528:DC%2BD1cXjtVygsLk%3D, PID: 18237311
    • Scanlan PD, Shanahan F, Clune Y et al. Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis. Environ Microbiol 2008; 10: 789–798.
    • (2008) Environ Microbiol , vol.10 , pp. 789-798
    • Scanlan, P.D.1    Shanahan, F.2    Clune, Y.3
  • 90
    • 79551571717 scopus 로고    scopus 로고
    • Microbial dysbiosis in colorectal cancer (CRC) patients
    • Sobhani I, Tap J, Roudot-Thoraval F et al. Microbial dysbiosis in colorectal cancer (CRC) patients. PLoS One 2011; 6: el6393.
    • (2011) PLoS One , vol.6 , pp. el6393
    • Sobhani, I.1    Tap, J.2    Roudot-Thoraval, F.3
  • 91
    • 32144458061 scopus 로고    scopus 로고
    • Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO. The Obesity Society
    • COI: 1:CAS:528:DC%2BD2MXht1ektLnM, PID: 16280421
    • Villareal DT, Apovian CM, Kushner RF et al. Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO. The Obesity Society. Am J Clin Nutr 2005; 82: 923–934.
    • (2005) Am J Clin Nutr , vol.82 , pp. 923-934
    • Villareal, D.T.1    Apovian, C.M.2    Kushner, R.F.3
  • 92
    • 75549083155 scopus 로고    scopus 로고
    • Obesity in Elderly Subjects In sheep’s clothing perhaps, but still a wolf!
    • PID: 19875588
    • Osher E, Stern N. Obesity in Elderly Subjects In sheep’s clothing perhaps, but still a wolf! Diabetes care 2009; 32: S398–S402.
    • (2009) Diabetes care , vol.32 , pp. S398-S402
    • Osher, E.1    Stern, N.2
  • 94
    • 73949137604 scopus 로고    scopus 로고
    • Microbiota and SCFA in lean and overweight healthy subjects
    • PID: 19498350
    • Schwiertz A, Taras D, Schäfer K et al. Microbiota and SCFA in lean and overweight healthy subjects. Obesity 2010; 18: 190–195.
    • (2010) Obesity , vol.18 , pp. 190-195
    • Schwiertz, A.1    Taras, D.2    Schäfer, K.3
  • 95
    • 56549122798 scopus 로고    scopus 로고
    • Human colonic microbiota associated with diet, obesity and weight loss
    • COI: 1:STN:280:DC%2BD1cjktFGjuw%3D%3D
    • Duncan S, Lobley G, Holtrop G et al. Human colonic microbiota associated with diet, obesity and weight loss. Int J Obes 2008; 32: 1720–1724.
    • (2008) Int J Obes , vol.32 , pp. 1720-1724
    • Duncan, S.1    Lobley, G.2    Holtrop, G.3
  • 96
    • 79959467647 scopus 로고    scopus 로고
    • Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans
    • COI: 1:CAS:528:DC%2BC3MXot1Khtrc%3D, PID: 21543530
    • Jumpertz R, Le DS, Turnbaugh PJ et al. Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans. Am J Clin Nutr 2011; 94: 58–65.
    • (2011) Am J Clin Nutr , vol.94 , pp. 58-65
    • Jumpertz, R.1    Le, D.S.2    Turnbaugh, P.J.3
  • 97
    • 22844454981 scopus 로고    scopus 로고
    • Eating your way to a successful old age, with special reference to older women
    • COI: 1:STN:280:DC%2BC2czis1Sktg%3D%3D, PID: 24394166
    • Horwath C, Kouris-Blazos A, Savige GS et al. Eating your way to a successful old age, with special reference to older women. Asia Pac J Clin Nutr 1999; 8: 216–225.
    • (1999) Asia Pac J Clin Nutr , vol.8 , pp. 216-225
    • Horwath, C.1    Kouris-Blazos, A.2    Savige, G.S.3
  • 98
    • 33748512579 scopus 로고    scopus 로고
    • Diabetes in the elderly
    • PID: 16962849
    • Meneilly GS. Diabetes in the elderly. Med Clin North Am 2006; 90: 909–923.
    • (2006) Med Clin North Am , vol.90 , pp. 909-923
    • Meneilly, G.S.1
  • 99
    • 0035160241 scopus 로고    scopus 로고
    • Diabetes in elderly adults
    • Meneilly GS, Tessier D. Diabetes in elderly adults. J Gerontol 2001; 56A: M5–M13.
    • (2001) J Gerontol , vol.56A , pp. M5-M13
    • Meneilly, G.S.1    Tessier, D.2
  • 100
    • 84870989233 scopus 로고    scopus 로고
    • Diabetes in older adults: a consensus report
    • COI: 1:STN:280:DC%2BC3s%2FovVygsA%3D%3D, PID: 23106132
    • Sue Kirkman M, Briscoe VJ, Clark N et al. Diabetes in older adults: a consensus report. J Am Geriatr Soc 2012; 60: 2342–2356.
    • (2012) J Am Geriatr Soc , vol.60 , pp. 2342-2356
    • Sue Kirkman, M.1    Briscoe, V.J.2    Clark, N.3
  • 101
    • 84867074831 scopus 로고    scopus 로고
    • A metagenome-wide association study of gut microbiota in type 2 diabetes
    • COI: 1:CAS:528:DC%2BC38XhsVaqt7fJ, PID: 23023125
    • Qin J, Li Y, Cai Z et al. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 2012; 490: 55–60.
    • (2012) Nature , vol.490 , pp. 55-60
    • Qin, J.1    Li, Y.2    Cai, Z.3
  • 102
    • 33645734597 scopus 로고    scopus 로고
    • Gut flora and bacterial translocation in chronic liver disease
    • PID: 16570339
    • Almeida J, Galhenage S, Yu J et al. Gut flora and bacterial translocation in chronic liver disease. World J Gastroenterol 2006; 12: 1493–1502.
    • (2006) World J Gastroenterol , vol.12 , pp. 1493-1502
    • Almeida, J.1    Galhenage, S.2    Yu, J.3
  • 103
    • 0036642444 scopus 로고    scopus 로고
    • Nosocomial spontaneous bacterial peritonitis and bacteremia in cirrhotic patients: impact of isolate type on prognosis and characteristics of infection
    • PID: 12060868
    • Campillo B, Richardet J-P, Kheo T et al. Nosocomial spontaneous bacterial peritonitis and bacteremia in cirrhotic patients: impact of isolate type on prognosis and characteristics of infection. Clin Infect Dis 2002; 35: 1–10.
    • (2002) Clin Infect Dis , vol.35 , pp. 1-10
    • Campillo, B.1    Richardet, J.-P.2    Kheo, T.3
  • 104
    • 73749087464 scopus 로고    scopus 로고
    • Effects of a gluten-free diet on gut microbiota and immune function in healthy adult human subjects
    • PID: 19445821
    • De Palma G, Nadal I, Collado MC et al. Effects of a gluten-free diet on gut microbiota and immune function in healthy adult human subjects. Br J Nutr 2009; 102: 1154–1160.
    • (2009) Br J Nutr , vol.102 , pp. 1154-1160
    • De Palma, G.1    Nadal, I.2    Collado, M.C.3
  • 105
    • 77954832695 scopus 로고    scopus 로고
    • Effects of a gluten-free diet on gut microbiota and immune function in healthy adult humans
    • PID: 21327021
    • Sanz Y. Effects of a gluten-free diet on gut microbiota and immune function in healthy adult humans. Gut Microbes 2010; 1: 135–137.
    • (2010) Gut Microbes , vol.1 , pp. 135-137
    • Sanz, Y.1
  • 106
    • 49049094399 scopus 로고    scopus 로고
    • Fecal microbiota in early rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BD1cXhtV2lsr7I, PID: 18528968
    • Vaahtovuo J, Munukka E, KorkeamÄKi M et al. Fecal microbiota in early rheumatoid arthritis. J Rheumatol 2008; 35: 1500–1505.
    • (2008) J Rheumatol , vol.35 , pp. 1500-1505
    • Vaahtovuo, J.1    Munukka, E.2    KorkeamÄKi, M.3
  • 107
    • 84885389457 scopus 로고    scopus 로고
    • Ageing and gut microbes: perspectives for health maintenance and longevity
    • Biagi E, Candela M, Turroni S et al. Ageing and gut microbes: perspectives for health maintenance and longevity. Pharmacol Res 2012.
    • (2012) Pharmacol Res
    • Biagi, E.1    Candela, M.2    Turroni, S.3
  • 108
    • 34547134453 scopus 로고    scopus 로고
    • Frailty in older men: prevalence, progression, and relationship with mortality
    • PID: 17661960
    • Cawthon PM, Marshall LM, Michael Y et al. Frailty in older men: prevalence, progression, and relationship with mortality. Journal of the American Geriatrics Society 2007; 55: 1216–1223.
    • (2007) Journal of the American Geriatrics Society , vol.55 , pp. 1216-1223
    • Cawthon, P.M.1    Marshall, L.M.2    Michael, Y.3
  • 109
    • 34547134453 scopus 로고    scopus 로고
    • Frailty in older men: prevalence, progression, and relationship with mortality
    • PID: 17661960
    • Cawthon PM, Marshall LM, Michael Y et al. Frailty in older men: prevalence, progression, and relationship with mortality. J Am Geriatr Soc 2007; 55: 1216–1223.
    • (2007) J Am Geriatr Soc , vol.55 , pp. 1216-1223
    • Cawthon, P.M.1    Marshall, L.M.2    Michael, Y.3
  • 110
    • 33644860220 scopus 로고    scopus 로고
    • Frailty in older adults: insights and interventions
    • PID: 16392724
    • Espinoza S, Walston JD. Frailty in older adults: insights and interventions. Cleve Clin J Med 2005; 72: 1105–1112.
    • (2005) Cleve Clin J Med , vol.72 , pp. 1105-1112
    • Espinoza, S.1    Walston, J.D.2
  • 111
    • 68949166843 scopus 로고    scopus 로고
    • Factors associated with changing cognitive function in older adults: implications for nursing rehabilitation
    • PID: 18517147
    • Myers JS. Factors associated with changing cognitive function in older adults: implications for nursing rehabilitation. Rehabil Nurs 2008; 33: 117–123; discussion 132.
    • (2008) Rehabil Nurs , vol.33 , pp. 117-123
    • Myers, J.S.1
  • 112
    • 68949166843 scopus 로고    scopus 로고
    • Factors associated with changing cognitive function in older adults: Implications for nursing rehabilitation
    • Myers JS. Factors associated with changing cognitive function in older adults: Implications for nursing rehabilitation. Rehabil Nursing 2008; 33: 117–123.
    • (2008) Rehabil Nursing , vol.33 , pp. 117-123
    • Myers, J.S.1
  • 113
    • 33846614149 scopus 로고    scopus 로고
    • Women who maintain optimal cognitive function into old age
    • PID: 17302664
    • Barnes DE, Cauley JA, Lui LY et al. Women who maintain optimal cognitive function into old age. J Am Geriatr Soc 2007; 55: 259–264.
    • (2007) J Am Geriatr Soc , vol.55 , pp. 259-264
    • Barnes, D.E.1    Cauley, J.A.2    Lui, L.Y.3
  • 114
    • 84892844794 scopus 로고    scopus 로고
    • Nutritional supplementation during resistance training improved skeletal muscle mass in community-dwelling frail older adults
    • Yamada M, Arai H, Yoshimura K et al. Nutritional supplementation during resistance training improved skeletal muscle mass in community-dwelling frail older adults. J Frailty Aging 2012; 1: 64–70.
    • (2012) J Frailty Aging , vol.1 , pp. 64-70
    • Yamada, M.1    Arai, H.2    Yoshimura, K.3
  • 115
    • 39649085837 scopus 로고    scopus 로고
    • Inflammaging as a major characteristic of old people: can it be prevented or cured?
    • PID: 18240544
    • Franceschi C. Inflammaging as a major characteristic of old people: can it be prevented or cured? Nutr Rev 2007; 65: S173–S176.
    • (2007) Nutr Rev , vol.65 , pp. S173-S176
    • Franceschi, C.1
  • 116
    • 58149358477 scopus 로고    scopus 로고
    • Immune receptor signaling, aging and autoimmunity
    • COI: 1:CAS:528:DC%2BC3cXhtlemtrbJ, PID: 19065799
    • Larbi A, Fülöp T, Pawelec G. Immune receptor signaling, aging and autoimmunity. Adv Exp Med Biol 2008; 640: 312–324.
    • (2008) Adv Exp Med Biol , vol.640 , pp. 312-324
    • Larbi, A.1    Fülöp, T.2    Pawelec, G.3
  • 117
    • 15244348518 scopus 로고    scopus 로고
    • The origins of age-related proinflammatory state
    • COI: 1:CAS:528:DC%2BD2MXisFSktro%3D, PID: 15572589
    • Ferrucci L, Corsi A, Lauretani F et al. The origins of age-related proinflammatory state. Blood 2005; 105: 2294–2299.
    • (2005) Blood , vol.105 , pp. 2294-2299
    • Ferrucci, L.1    Corsi, A.2    Lauretani, F.3
  • 118
    • 0033134682 scopus 로고    scopus 로고
    • Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly
    • COI: 1:STN:280:DyaK1M3ms1OmsA%3D%3D, PID: 10335721
    • Harris TB, Ferrucci L, Tracy RP et al. Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am J Med 1999; 106: 506–512.
    • (1999) Am J Med , vol.106 , pp. 506-512
    • Harris, T.B.1    Ferrucci, L.2    Tracy, R.P.3
  • 119
    • 0037374849 scopus 로고    scopus 로고
    • Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10-1082 promoter SNP and its interaction with TNF-α-308 promoter SNP
    • COI: 1:CAS:528:DC%2BD3sXjslegu78%3D, PID: 12676903
    • Lio D, Scola L, Crivello A et al. Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10-1082 promoter SNP and its interaction with TNF-α-308 promoter SNP. J Med Genet 2003; 40: 296–299.
    • (2003) J Med Genet , vol.40 , pp. 296-299
    • Lio, D.1    Scola, L.2    Crivello, A.3
  • 120
    • 4444300916 scopus 로고    scopus 로고
    • Immunity and aging: the enemy within?
    • COI: 1:CAS:528:DC%2BD2cXms1eitLo%3D, PID: 15268753
    • DeVeale B, Brummel T, Seroude L. Immunity and aging: the enemy within? Aging Cell 2004; 3: 195–208.
    • (2004) Aging Cell , vol.3 , pp. 195-208
    • DeVeale, B.1    Brummel, T.2    Seroude, L.3
  • 121
    • 33846656968 scopus 로고    scopus 로고
    • Immunosenescence of ageing
    • COI: 1:CAS:528:DC%2BD2sXisFyksbc%3D, PID: 17200946
    • Gruver AL, Hudson LL, Sempowski GD. Immunosenescence of ageing. J Pathol 2007; 211: 144–156.
    • (2007) J Pathol , vol.211 , pp. 144-156
    • Gruver, A.L.1    Hudson, L.L.2    Sempowski, G.D.3
  • 122
    • 57149086454 scopus 로고    scopus 로고
    • Immunosenescence and immunogenetics of human longevity
    • COI: 1:CAS:528:DC%2BD1cXhsVeqsr3I, PID: 19047800
    • Ostan R, Bucci L, Capri M et al. Immunosenescence and immunogenetics of human longevity. Neuroimmunomodulation 2008; 15: 224–240.
    • (2008) Neuroimmunomodulation , vol.15 , pp. 224-240
    • Ostan, R.1    Bucci, L.2    Capri, M.3
  • 124
    • 78650843522 scopus 로고    scopus 로고
    • To be or not to be a pathogen: that is the mucosally relevant question
    • PID: 21150896
    • Sansonetti PJ. To be or not to be a pathogen: that is the mucosally relevant question. Mucosal Immunol 2010; 4: 8–14.
    • (2010) Mucosal Immunol , vol.4 , pp. 8-14
    • Sansonetti, P.J.1
  • 125
    • 67649400909 scopus 로고    scopus 로고
    • Mucosal immunosenescence: new developments and vaccines to control infectious diseases
    • COI: 1:CAS:528:DC%2BD1MXotF2gtrY%3D, PID: 19540811
    • Fujihashi K, Kiyono H. Mucosal immunosenescence: new developments and vaccines to control infectious diseases. Trends Immunol 2009; 30: 334–343.
    • (2009) Trends Immunol , vol.30 , pp. 334-343
    • Fujihashi, K.1    Kiyono, H.2
  • 126
    • 0032770726 scopus 로고    scopus 로고
    • Geriatric cachexia: the role of cytokines
    • COI: 1:CAS:528:DyaK1MXkvFCrs7o%3D, PID: 10426694
    • Yeh S-S, Schuster MW. Geriatric cachexia: the role of cytokines. Am J Clin Nutr 1999; 70: 183–197.
    • (1999) Am J Clin Nutr , vol.70 , pp. 183-197
    • Yeh, S.-S.1    Schuster, M.W.2
  • 127
    • 84880976146 scopus 로고    scopus 로고
    • The interaction between gut microbiota and age-related changes in immune function and inflammation
    • PID: 23915308
    • Magrone T, Jirillo E. The interaction between gut microbiota and age-related changes in immune function and inflammation. Immun Ageing 2013; 10: 31.
    • (2013) Immun Ageing , vol.10 , pp. 31
    • Magrone, T.1    Jirillo, E.2
  • 128
    • 37349103420 scopus 로고    scopus 로고
    • The inflammatory status of old age can be nurtured from the intestinal environment
    • PID: 18090652
    • Guigoz Y, Doré J, Schiffrin EJ. The inflammatory status of old age can be nurtured from the intestinal environment. Curr Opin Clin Nutr Metab Care 2008; 11: 13–20.
    • (2008) Curr Opin Clin Nutr Metab Care , vol.11 , pp. 13-20
    • Guigoz, Y.1    Doré, J.2    Schiffrin, E.J.3
  • 129
    • 43349095250 scopus 로고    scopus 로고
    • Bifidobacterium microbiota and parameters of immune function in elderly subjects
    • COI: 1:CAS:528:DC%2BD1cXntFartbs%3D, PID: 18336547
    • Ouwehand AC, Bergsma N, Parhiala R et al. Bifidobacterium microbiota and parameters of immune function in elderly subjects. FEMS Immunol Med Microbiol 2008; 53: 18–25.
    • (2008) FEMS Immunol Med Microbiol , vol.53 , pp. 18-25
    • Ouwehand, A.C.1    Bergsma, N.2    Parhiala, R.3
  • 130
    • 77950669604 scopus 로고    scopus 로고
    • The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice
    • Turnbaugh PJ, Ridaura VK, Faith JJ et al. The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med 2009;1:6–14.
    • (2009) Sci Transl Med , vol.1 , pp. 6-14
    • Turnbaugh, P.J.1    Ridaura, V.K.2    Faith, J.J.3
  • 132
    • 0028206693 scopus 로고
    • Decreased maturation of T-cell populations in the healthy elderly: Influence of nutritional factors on the appearance of double negative CD4-, CD8-, CD2+ cells
    • PID: 18649854
    • Lesourd BM, Laisney C, Salvatore R et al. Decreased maturation of T-cell populations in the healthy elderly: Influence of nutritional factors on the appearance of double negative CD4-, CD8-, CD2+ cells. Arch Gerontol Geriatr 1994; 19: 139–154.
    • (1994) Arch Gerontol Geriatr , vol.19 , pp. 139-154
    • Lesourd, B.M.1    Laisney, C.2    Salvatore, R.3
  • 133
    • 48249125816 scopus 로고    scopus 로고
    • Causes of vitamin B12 and folate deficiency
    • Allen LH. Causes of vitamin B12 and folate deficiency. Food Nutr Bull 2008; 29: 20–34.
    • (2008) Food Nutr Bull , vol.29 , pp. 20-34
    • Allen, L.H.1
  • 134
    • 0028432222 scopus 로고
    • Fibre intake in elderly individuals with poor masticatory performance
    • COI: 1:STN:280:DyaK2c3ntlSisQ%3D%3D, PID: 8004522
    • Laurin D, Brodeur J-M, Bourdages J et al. Fibre intake in elderly individuals with poor masticatory performance. J Can Dent Assoc 1994; 60: 443–446.
    • (1994) J Can Dent Assoc , vol.60 , pp. 443-446
    • Laurin, D.1    Brodeur, J.-M.2    Bourdages, J.3
  • 135
    • 0036212734 scopus 로고    scopus 로고
    • Swallowing disorders in the elderly
    • Schindler JS, Kelly JH. Swallowing disorders in the elderly. Laryngoscope 2009; 112: 589–602.
    • (2009) Laryngoscope , vol.112 , pp. 589-602
    • Schindler, J.S.1    Kelly, J.H.2
  • 136
    • 0027600136 scopus 로고
    • Constipation in elderly patients: Pathogenesis and management
    • COI: 1:STN:280:DyaK3szhtleisA%3D%3D, PID: 8324297
    • Wald A. Constipation in elderly patients: Pathogenesis and management. Drugs Aging 1993; 3: 220–220.
    • (1993) Drugs Aging , vol.3 , pp. 220
    • Wald, A.1
  • 137
    • 10344243993 scopus 로고    scopus 로고
    • The treatment of chronic constipation in elderly people: an update
    • PID: 15554750
    • Bosshard W, Dreher R, Schnegg J-F et al. The treatment of chronic constipation in elderly people: an update. Drugs Aging 2004; 21: 911–930.
    • (2004) Drugs Aging , vol.21 , pp. 911-930
    • Bosshard, W.1    Dreher, R.2    Schnegg, J.-F.3
  • 138
    • 80053618114 scopus 로고    scopus 로고
    • Linking long-term dietary patterns with gut microbial enterotypes
    • COI: 1:CAS:528:DC%2BC3MXht1Gms77K, PID: 21885731
    • Wu GD, Chen J, Hoffmann C et al. Linking long-term dietary patterns with gut microbial enterotypes. Science 2011; 334: 105–108.
    • (2011) Science , vol.334 , pp. 105-108
    • Wu, G.D.1    Chen, J.2    Hoffmann, C.3
  • 139
    • 23344442120 scopus 로고    scopus 로고
    • Obesity alters gut microbial ecology
    • COI: 1:CAS:528:DC%2BD2MXnvVWju7g%3D
    • Ley RE, Bäckhed F, Turnbaugh P et al. Obesity alters gut microbial ecology. Proc Natl Acad Sci US A 2005; 102: 11070–11075.
    • (2005) Proc Natl Acad Sci US A , vol.102 , pp. 11070-11075
    • Ley, R.E.1    Bäckhed, F.2    Turnbaugh, P.3
  • 140
    • 0032770053 scopus 로고    scopus 로고
    • High-meat diets and cancer risk
    • COI: 1:STN:280:DyaK1MzpsFKmtA%3D%3D, PID: 10466162
    • Bingham SA. High-meat diets and cancer risk. Proc Nutr Soc 1999; 58: 243–248.
    • (1999) Proc Nutr Soc , vol.58 , pp. 243-248
    • Bingham, S.A.1
  • 141
    • 84876040553 scopus 로고    scopus 로고
    • Diet and Functional Foods in Treatment and Maintenance Therapy of Colon Disorders
    • Kumar D, Singh G, Singh M et al. Diet and Functional Foods in Treatment and Maintenance Therapy of Colon Disorders. J Appl Pharma Sci 2012; 2: 177–187.
    • (2012) J Appl Pharma Sci , vol.2 , pp. 177-187
    • Kumar, D.1    Singh, G.2    Singh, M.3
  • 142
    • 3042590934 scopus 로고    scopus 로고
    • The causes of intestinal dysbiosis: a review
    • Myers SP. The causes of intestinal dysbiosis: a review. Altera Med Rev 2004; 9: 180–197.
    • (2004) Altera Med Rev , vol.9 , pp. 180-197
    • Myers, S.P.1
  • 143
    • 0029883793 scopus 로고    scopus 로고
    • Resistant starch lowers fecal concentrations of ammonia and phenols in humans
    • COI: 1:CAS:528:DyaK28XjtVylt7Y%3D, PID: 8615362
    • Birkett A, Muir J, Phillips J et al. Resistant starch lowers fecal concentrations of ammonia and phenols in humans. Am J Clin Nutr 1996; 63: 766–772.
    • (1996) Am J Clin Nutr , vol.63 , pp. 766-772
    • Birkett, A.1    Muir, J.2    Phillips, J.3
  • 144
    • 0018718884 scopus 로고
    • The effect of meat protein and dietary fiber on colonic function and metabolism; II. Bacterial metabolites in feces and urine
    • COI: 1:CAS:528:DyaL3cXltFam, PID: 484528
    • Cummings JH, Hill MJ, Bone ES et al. The effect of meat protein and dietary fiber on colonic function and metabolism; II. Bacterial metabolites in feces and urine. Am J Clin Nutr 1979; 32: 2094–2101.
    • (1979) Am J Clin Nutr , vol.32 , pp. 2094-2101
    • Cummings, J.H.1    Hill, M.J.2    Bone, E.S.3
  • 145
    • 0025873114 scopus 로고
    • Effect of diets low and high in refined sugars on gut transit, bile acid metabolism and bacterial fermentation
    • COI: 1:CAS:528:DyaK3MXlsFOktbo%3D, PID: 2026335
    • Kruis W, Forstmaier G, Scheurlen C et al. Effect of diets low and high in refined sugars on gut transit, bile acid metabolism and bacterial fermentation. Gut 1991; 32: 367–371.
    • (1991) Gut , vol.32 , pp. 367-371
    • Kruis, W.1    Forstmaier, G.2    Scheurlen, C.3
  • 146
    • 34248152283 scopus 로고    scopus 로고
    • Long-term ecological impacts of antibiotic administration on the human intestinal microbiota
    • COI: 1:CAS:528:DC%2BD1cXksFSgu7k%3D, PID: 18043614
    • Jernberg C, Löfmark S, Edlund C et al. Long-term ecological impacts of antibiotic administration on the human intestinal microbiota. ISME J 2007; 1: 56–66.
    • (2007) ISME J , vol.1 , pp. 56-66
    • Jernberg, C.1    Löfmark, S.2    Edlund, C.3
  • 147
    • 0001490691 scopus 로고
    • Ecological effects of antimicrobial agents on the human intestinal microflora
    • Nord CE, Edlund C. Ecological effects of antimicrobial agents on the human intestinal microflora. Microbial Ecol Health Dis 1991; 4: 193–207.
    • (1991) Microbial Ecol Health Dis , vol.4 , pp. 193-207
    • Nord, C.E.1    Edlund, C.2
  • 148
    • 78049494788 scopus 로고    scopus 로고
    • Short-term antibiotic treatment has differing long-term impacts on the human throat and gut microbiome
    • PID: 20352091
    • Jakobsson HE, Jernberg C, Andersson AF et al. Short-term antibiotic treatment has differing long-term impacts on the human throat and gut microbiome. PLoS One 2010;5:e9836.
    • (2010) PLoS One , vol.5
    • Jakobsson, H.E.1    Jernberg, C.2    Andersson, A.F.3
  • 149
    • 78049522796 scopus 로고    scopus 로고
    • Long-term impacts of antibiotic exposure on the human intestinal microbiota
    • COI: 1:CAS:528:DC%2BC3cXhsFCiur3F
    • Jernberg C, Löfmark S, Edlund C et al. Long-term impacts of antibiotic exposure on the human intestinal microbiota. Microbiol 2010; 156: 3216–3223.
    • (2010) Microbiol , vol.156 , pp. 3216-3223
    • Jernberg, C.1    Löfmark, S.2    Edlund, C.3
  • 150
    • 79952756960 scopus 로고    scopus 로고
    • Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation
    • COI: 1:CAS:528:DC%2BC3MXjvVCktbo%3D, PID: 20847294
    • Dethlefsen L, Relman DA. Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation. Proc Natl Acad Sci U S A 2011; 108: 4554–4561.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4554-4561
    • Dethlefsen, L.1    Relman, D.A.2
  • 151
    • 0038730576 scopus 로고    scopus 로고
    • Use of denaturing gradient gel electrophoresis for analysis of the stool microbiota of hospitalized patients
    • COI: 1:CAS:528:DC%2BD3sXktFWnu7g%3D
    • Donskey CJ, Hujer AM, Das SM et al. Use of denaturing gradient gel electrophoresis for analysis of the stool microbiota of hospitalized patients. J Microbiol Meth 2003; 54: 249–256.
    • (2003) J Microbiol Meth , vol.54 , pp. 249-256
    • Donskey, C.J.1    Hujer, A.M.2    Das, S.M.3
  • 152
    • 8144221776 scopus 로고    scopus 로고
    • Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects
    • COI: 1:CAS:528:DC%2BD2cXosl2hs74%3D, PID: 15466557
    • Woodmansey EJ, McMurdo MET, Macfarlane GT et al. Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects. Appl Environ Microbiol 2004; 70: 6113–6122.
    • (2004) Appl Environ Microbiol , vol.70 , pp. 6113-6122
    • Woodmansey, E.J.1    McMurdo, M.E.T.2    Macfarlane, G.T.3
  • 153
    • 77952679997 scopus 로고    scopus 로고
    • Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile
    • COI: 1:CAS:528:DC%2BC3cXmslGrur4%3D, PID: 20435915
    • Rea MC, Sit CS, Clayton E et al. Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile. Proc Natl Acad Sci U S A 2010; 107: 9352–9357.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 9352-9357
    • Rea, M.C.1    Sit, C.S.2    Clayton, E.3
  • 154
    • 79952773376 scopus 로고    scopus 로고
    • Effect of broad-and narrow-spectrum antimicrobials on Clostridium difficile and microbial diversity in a model of the distal colon
    • COI: 1:CAS:528:DC%2BC3MXjvVCrsr0%3D, PID: 20616009
    • Rea MC, Dobson A, O’Sullivan O et al. Effect of broad-and narrow-spectrum antimicrobials on Clostridium difficile and microbial diversity in a model of the distal colon. Proc Natl Acad Sci U S A 2011; 108: 4639–4644.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4639-4644
    • Rea, M.C.1    Dobson, A.2    O’Sullivan, O.3
  • 155
    • 28444471613 scopus 로고    scopus 로고
    • Antibiotic resistance in food lactic acid bacteria—a review
    • COI: 1:CAS:528:DC%2BD2MXht1Orsr3I, PID: 16289406
    • Mathur S, Singh R. Antibiotic resistance in food lactic acid bacteria—a review. Int J Food Microbiol 2005; 105: 281–295.
    • (2005) Int J Food Microbiol , vol.105 , pp. 281-295
    • Mathur, S.1    Singh, R.2
  • 157
    • 0141462552 scopus 로고    scopus 로고
    • Long-term persistence of resistant Enterococcus species after antibiotics to eradicate Helicobacter pylori
    • PID: 13679325
    • Sjölund M, Wreiber K, Andersson DI et al. Long-term persistence of resistant Enterococcus species after antibiotics to eradicate Helicobacter pylori. Ann Intern Med 2003; 139: 483–487.
    • (2003) Ann Intern Med , vol.139 , pp. 483-487
    • Sjölund, M.1    Wreiber, K.2    Andersson, D.I.3
  • 158
    • 1542513850 scopus 로고    scopus 로고
    • Antibiotic-associated diarrhea accompanied by large-scale alterations in the composition of the fecal microbiota
    • PID: 15004076
    • Young VB, Schmidt TM. Antibiotic-associated diarrhea accompanied by large-scale alterations in the composition of the fecal microbiota. J Clin Microbiol 2004; 42: 1203–1206.
    • (2004) J Clin Microbiol , vol.42 , pp. 1203-1206
    • Young, V.B.1    Schmidt, T.M.2
  • 159
    • 0035468838 scopus 로고    scopus 로고
    • Effect of antimicrobial agents on the ecological balance of human microflora
    • COI: 1:CAS:528:DC%2BD38XltVOntbs%3D, PID: 11871461
    • Sullivan Å, Edlund C, Nord CE. Effect of antimicrobial agents on the ecological balance of human microflora. Lancet Infect Dis 2001; 1: 101–114.
    • (2001) Lancet Infect Dis , vol.1 , pp. 101-114
    • Sullivan1    Edlund, C.2    Nord, C.E.3
  • 160
    • 50649112615 scopus 로고    scopus 로고
    • Gastric acid suppression by proton pump inhibitors as a risk factor for Clostridium difficile-associated diarrhea in hospitalized patients
    • PID: 18702653
    • Aseeri M, Schroeder T, Kramer J et al. Gastric acid suppression by proton pump inhibitors as a risk factor for Clostridium difficile-associated diarrhea in hospitalized patients. Am J Gastroenterol 2008; 103: 2308–2313.
    • (2008) Am J Gastroenterol , vol.103 , pp. 2308-2313
    • Aseeri, M.1    Schroeder, T.2    Kramer, J.3
  • 161
    • 0035695398 scopus 로고    scopus 로고
    • Incidence, prevalence, and management of opioid bowel dysfunction
    • COI: 1:STN:280:DC%2BD38%2FksVyhug%3D%3D, PID: 11755892
    • Pappagallo M. Incidence, prevalence, and management of opioid bowel dysfunction. Am J Surg 2001; 182: 11S–18S.
    • (2001) Am J Surg , vol.182 , pp. 11S-18S
    • Pappagallo, M.1
  • 162
    • 34247489795 scopus 로고    scopus 로고
    • Intestinal malabsorption in the elderly
    • PID: 17468550
    • Holt PR. Intestinal malabsorption in the elderly. Dig Dis 2007; 25: 144–150.
    • (2007) Dig Dis , vol.25 , pp. 144-150
    • Holt, P.R.1
  • 163
    • 0027496032 scopus 로고
    • Vestibular ototoxicity. Clinical considerations
    • COI: 1:STN:280:DyaK2c%2FltFahug%3D%3D, PID: 8233485
    • Black FO, Pesznecker SC. Vestibular ototoxicity. Clinical considerations. Otolaryngol Clin North Am 1993; 26: 713–736.
    • (1993) Otolaryngol Clin North Am , vol.26 , pp. 713-736
    • Black, F.O.1    Pesznecker, S.C.2
  • 164
    • 0031545034 scopus 로고    scopus 로고
    • Selecting the right antibiotics for elderly patients
    • Millan J, Gleckman R. Selecting the right antibiotics for elderly patients. J Crit Illness 1997; 12: 590–598.
    • (1997) J Crit Illness , vol.12 , pp. 590-598
    • Millan, J.1    Gleckman, R.2
  • 165
    • 84949953083 scopus 로고    scopus 로고
    • Evaluation of health and nutritional properties of probiotics in food including powder milk with live lactic acid bacteria
    • FAO/WHO. Evaluation of health and nutritional properties of probiotics in food including powder milk with live lactic acid bacteria. Joint FAO/WHO Expert Consultation, Food and Agriculture Organisation of the United Nations. Córdoba. Argentina October 2001: 1–4.
    • (2001) Joint FAO/WHO Expert Consultation, Food and Agriculture Organisation of the United Nations , pp. 1-4
    • FAO/WHO1
  • 166
    • 0032824799 scopus 로고    scopus 로고
    • Probiotics: from myth to reality. Demonstration of functionality in animal models of disease and in human clinical trials
    • COI: 1:STN:280:DC%2BD3c%2FgtVWrtg%3D%3D, PID: 10532384
    • Dunne C, Murphy L, Flynn S et al. Probiotics: from myth to reality. Demonstration of functionality in animal models of disease and in human clinical trials. Antonie Van Leeuwenhoek 1999; 76: 279–292.
    • (1999) Antonie Van Leeuwenhoek , vol.76 , pp. 279-292
    • Dunne, C.1    Murphy, L.2    Flynn, S.3
  • 167
    • 84863487815 scopus 로고    scopus 로고
    • Probiotics in the gastrointestinal diseases of the elderly
    • COI: 1:STN:280:DC%2BC38rks1OntQ%3D%3D, PID: 22499466
    • Malaguarnera G, Leggio F, Vacante M et al. Probiotics in the gastrointestinal diseases of the elderly. J Nutr Health Aging 2012; 16: 402–410.
    • (2012) J Nutr Health Aging , vol.16 , pp. 402-410
    • Malaguarnera, G.1    Leggio, F.2    Vacante, M.3
  • 168
    • 4043081339 scopus 로고    scopus 로고
    • Production of Antimicrobial Substances by Lactic Acid Bacteria II: screening bacteriocin-producing strains with probiotic purposes and characterization of a Lactobacillus bacteriocin
    • PID: 15156045
    • Ocaña VS, Nader-Macías ME. Production of Antimicrobial Substances by Lactic Acid Bacteria II: screening bacteriocin-producing strains with probiotic purposes and characterization of a Lactobacillus bacteriocin. Methods Mol Biol 2004; 268: 347–353.
    • (2004) Methods Mol Biol , vol.268 , pp. 347-353
    • Ocaña, V.S.1    Nader-Macías, M.E.2
  • 169
    • 58149280200 scopus 로고    scopus 로고
    • Characterization of enterocin-and salivaricin-producing lactic acid bacteria from the mammalian gastrointestinal tract
    • PID: 19076236
    • O’Shea EF, Gardiner GE, O’Connor PM et al. Characterization of enterocin-and salivaricin-producing lactic acid bacteria from the mammalian gastrointestinal tract. FEMS Microbiol Lett 2008; 291: 24–34.
    • (2008) FEMS Microbiol Lett , vol.291 , pp. 24-34
    • O’Shea, E.F.1    Gardiner, G.E.2    O’Connor, P.M.3
  • 170
    • 0032805445 scopus 로고    scopus 로고
    • Prebiotics, probiotics and human gut microbiology
    • Fooks LJ, Fuller R, Gibson GR. Prebiotics, probiotics and human gut microbiology. Int Dairy J 1999; 9: 53–61.
    • (1999) Int Dairy J , vol.9 , pp. 53-61
    • Fooks, L.J.1    Fuller, R.2    Gibson, G.R.3
  • 171
    • 12744273405 scopus 로고    scopus 로고
    • Dietary modulation of the human colonic microbiota: updating the concept of prebiotics
    • COI: 1:CAS:528:DC%2BD2MXht1yltr4%3D, PID: 19079930
    • Gibson GR, Probert HM, Van Loo J et al. Dietary modulation of the human colonic microbiota: updating the concept of prebiotics. Nutr Res Rev 2004; 17: 259–275.
    • (2004) Nutr Res Rev , vol.17 , pp. 259-275
    • Gibson, G.R.1    Probert, H.M.2    Van Loo, J.3
  • 172
    • 0035153288 scopus 로고    scopus 로고
    • Prebiotic digestion and fermentation
    • COI: 1:CAS:528:DC%2BD3MXpvF2hsw%3D%3D, PID: 11157351
    • Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001; 73: 415s–420s.
    • (2001) Am J Clin Nutr , vol.73 , pp. 415s-420s
    • Cummings, J.H.1    Macfarlane, G.T.2    Englyst, H.N.3
  • 173
    • 0007097659 scopus 로고
    • Successful treatment of relapsing Clostridium difficile colitis with Lactobacillus GG
    • COI: 1:STN:280:DyaL1c%2Fptlenug%3D%3D, PID: 2892070
    • Gorbach S, Chang T-W, Goldin B. Successful treatment of relapsing Clostridium difficile colitis with Lactobacillus GG. Lancet 1987; 2: 1519.
    • (1987) Lancet , vol.2 , pp. 1519
    • Gorbach, S.1    Chang, T.-W.2    Goldin, B.3
  • 174
    • 33748156955 scopus 로고    scopus 로고
    • Probiotics for the prevention of antibiotic-associated diarrhea and Clostridium difficile diarrhea
    • PID: 16633131
    • Katz JA. Probiotics for the prevention of antibiotic-associated diarrhea and Clostridium difficile diarrhea. J Clin Gastroenterol 2006; 40: 249–255.
    • (2006) J Clin Gastroenterol , vol.40 , pp. 249-255
    • Katz, J.A.1
  • 175
    • 24344476631 scopus 로고    scopus 로고
    • Probiotics as a treatment strategy for gastrointestinal diseases?
    • PID: 16113543
    • Bergonzelli GE, Blum S, Brüssow H et al. Probiotics as a treatment strategy for gastrointestinal diseases? Digestion 2005; 72: 57–68.
    • (2005) Digestion , vol.72 , pp. 57-68
    • Bergonzelli, G.E.1    Blum, S.2    Brüssow, H.3
  • 176
    • 0034013198 scopus 로고    scopus 로고
    • Enhancement of natural immune function by dietary consumption of Bifidobacterium lactis (HN019)
    • COI: 1:STN:280:DC%2BD3c7nvFKjug%3D%3D, PID: 10713750
    • Arunachalam K, Gill HS, Chandra RK. Enhancement of natural immune function by dietary consumption of Bifidobacterium lactis (HN019). Eur J Clin Nutr 2000; 54: 263–267.
    • (2000) Eur J Clin Nutr , vol.54 , pp. 263-267
    • Arunachalam, K.1    Gill, H.S.2    Chandra, R.K.3
  • 177
    • 0034969247 scopus 로고    scopus 로고
    • Dietary probiotic supplementation to enhance cellular immunity in the elderly
    • COI: 1:STN:280:DC%2BD3Mzos1egug%3D%3D, PID: 11440213
    • Gill HS, Cross ML, Rutherfurd KJ et al. Dietary probiotic supplementation to enhance cellular immunity in the elderly. Br J Biomed Sci 2001; 58: 94–96.
    • (2001) Br J Biomed Sci , vol.58 , pp. 94-96
    • Gill, H.S.1    Cross, M.L.2    Rutherfurd, K.J.3
  • 178
    • 0033843845 scopus 로고    scopus 로고
    • Modulation of humoral immune response through probiotic intake
    • Fang H, Elina T, Heikki A et al. Modulation of humoral immune response through probiotic intake. FEMS Immunol Med Microbiol 2006; 29: 47–52.
    • (2006) FEMS Immunol Med Microbiol , vol.29 , pp. 47-52
    • Fang, H.1    Elina, T.2    Heikki, A.3
  • 179
    • 0036693761 scopus 로고    scopus 로고
    • Probiotics: an overview of beneficial effects
    • COI: 1:CAS:528:DC%2BD38XnvVyitrY%3D, PID: 12369194
    • Ouwehand AC, Salminen S, Isolauri E. Probiotics: an overview of beneficial effects. Antonie Van Leeuwenhoek 2002; 82: 279–289.
    • (2002) Antonie Van Leeuwenhoek , vol.82 , pp. 279-289
    • Ouwehand, A.C.1    Salminen, S.2    Isolauri, E.3
  • 180
    • 72049119604 scopus 로고    scopus 로고
    • The probiotic preparation, VSL# 3 induces remission in patients with mild-to-moderately active ulcerative colitis
    • PID: 19631292
    • Sood A, Midha V, Makharia GK et al. The probiotic preparation, VSL# 3 induces remission in patients with mild-to-moderately active ulcerative colitis. Clin Gastroenterol Hepatol 2009; 7: 1202–1209.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 1202-1209
    • Sood, A.1    Midha, V.2    Makharia, G.K.3
  • 181
    • 0027996351 scopus 로고
    • Regulatory effects of bifidobacteria on the growth of other colonic bacteria
    • COI: 1:STN:280:DyaK2M%2FotFSgtw%3D%3D
    • Gibson GR, Wang X. Regulatory effects of bifidobacteria on the growth of other colonic bacteria. J Appl Microbiol 1994; 77: 412–420.
    • (1994) J Appl Microbiol , vol.77 , pp. 412-420
    • Gibson, G.R.1    Wang, X.2
  • 182
    • 33947239369 scopus 로고    scopus 로고
    • Impact of consumption of different levels of Bifidobacterium lactis HN019 on the intestinal microflora of elderly human subjects
    • COI: 1:STN:280:DC%2BD2s7hvFSrug%3D%3D, PID: 17315077
    • Ahmed M, Prasad J, Gill H et al. Impact of consumption of different levels of Bifidobacterium lactis HN019 on the intestinal microflora of elderly human subjects. J Nutr Health Aging 2007; 11: 26–31.
    • (2007) J Nutr Health Aging , vol.11 , pp. 26-31
    • Ahmed, M.1    Prasad, J.2    Gill, H.3
  • 183
    • 60849116412 scopus 로고    scopus 로고
    • Probiotics modulate the Bifidobacterium microbiota of elderly nursing home residents
    • PID: 19234769
    • Lahtinen SJ, Tammela L, Korpela J et al. Probiotics modulate the Bifidobacterium microbiota of elderly nursing home residents. Age 2009; 31: 59–66.
    • (2009) Age , vol.31 , pp. 59-66
    • Lahtinen, S.J.1    Tammela, L.2    Korpela, J.3
  • 184
    • 0036443902 scopus 로고    scopus 로고
    • Stimulation of the secretion of proinflammatory cytokines by Bifidobacterium strains
    • COI: 1:CAS:528:DC%2BD38XpvVSqtrc%3D, PID: 12516776
    • He F, Morita H, Ouwehand AC et al. Stimulation of the secretion of proinflammatory cytokines by Bifidobacterium strains. Microbiol Immunol 2002; 46: 781–785.
    • (2002) Microbiol Immunol , vol.46 , pp. 781-785
    • He, F.1    Morita, H.2    Ouwehand, A.C.3
  • 185
    • 33645900573 scopus 로고    scopus 로고
    • Towards understanding molecular modes of probiotic action
    • COI: 1:CAS:528:DC%2BD28Xjs1yitLg%3D, PID: 16510275
    • Marco ML, Pavan S, Kleerebezem M. Towards understanding molecular modes of probiotic action. Curr Opin Biotechnol 2006; 17: 204–210.
    • (2006) Curr Opin Biotechnol , vol.17 , pp. 204-210
    • Marco, M.L.1    Pavan, S.2    Kleerebezem, M.3
  • 186
    • 34547202163 scopus 로고    scopus 로고
    • Fermented cereal with specific bifidobacteria normalizes bowel movements in elderly nursing home residents. A randomized, controlled trial
    • COI: 1:STN:280:DC%2BD2svjt1aiuw%3D%3D, PID: 17653486
    • Pitkala KH, Strandberg TE, Finne-Soveri UH et al. Fermented cereal with specific bifidobacteria normalizes bowel movements in elderly nursing home residents. A randomized, controlled trial. J Nutr Health Aging 2007; 11: 305–311.
    • (2007) J Nutr Health Aging , vol.11 , pp. 305-311
    • Pitkala, K.H.1    Strandberg, T.E.2    Finne-Soveri, U.H.3
  • 187
    • 0033710591 scopus 로고    scopus 로고
    • Enhancing immunity by dietary consumption of a probiotic lactic acid bacterium (Bifidobacterium lactis HN019): optimization and definition of cellular immune responses
    • COI: 1:STN:280:DC%2BD3M3jtFOqtw%3D%3D, PID: 11114680
    • Chiang BL, Sheih YH, Wang LH et al. Enhancing immunity by dietary consumption of a probiotic lactic acid bacterium (Bifidobacterium lactis HN019): optimization and definition of cellular immune responses. Eur J Clin Nutr 2000; 54: 849–855.
    • (2000) Eur J Clin Nutr , vol.54 , pp. 849-855
    • Chiang, B.L.1    Sheih, Y.H.2    Wang, L.H.3
  • 188
    • 84872495758 scopus 로고    scopus 로고
    • A probiotics-containing biscuit modulates the intestinal microbiota in the elderly
    • COI: 1:STN:280:DC%2BC3szjvFWnug%3D%3D, PID: 23364497
    • Rampelli S, Candela M, Severgnini M et al. A probiotics-containing biscuit modulates the intestinal microbiota in the elderly. J Nutr Health Aging 2013; 17: 166–172.
    • (2013) J Nutr Health Aging , vol.17 , pp. 166-172
    • Rampelli, S.1    Candela, M.2    Severgnini, M.3
  • 189
    • 0035995860 scopus 로고    scopus 로고
    • Effect of probiotics on constipation, fecal azoreductase activity and fecal mucin content in the elderly
    • COI: 1:CAS:528:DC%2BD38XlvFOitb4%3D, PID: 12169860
    • Ouwehand AC, Lagström H, Suomalainen T et al. Effect of probiotics on constipation, fecal azoreductase activity and fecal mucin content in the elderly. Ann Nutr Metab 2002; 46: 159–162.
    • (2002) Ann Nutr Metab , vol.46 , pp. 159-162
    • Ouwehand, A.C.1    Lagström, H.2    Suomalainen, T.3
  • 190
    • 77951921882 scopus 로고    scopus 로고
    • Efficacy of Lactic Acid Bacteria (LAB) supplement in management of constipation among nursing home residents
    • An HM, Baek EH, Jang S et al. Efficacy of Lactic Acid Bacteria (LAB) supplement in management of constipation among nursing home residents. Nutr J 2010; 9: 1–7.
    • (2010) Nutr J , vol.9 , pp. 1-7
    • An, H.M.1    Baek, E.H.2    Jang, S.3
  • 191
    • 0037279208 scopus 로고    scopus 로고
    • Effect of fermented milk containing the probiotic Lactobacillus casei DN-114001 on winter infections in free-living elderly subjects: a randomised, controlled pilot study
    • COI: 1:STN:280:DC%2BD3s7mt1eqsg%3D%3D, PID: 12679825
    • Turchet P, Laurenzano M, Auboiron S et al. Effect of fermented milk containing the probiotic Lactobacillus casei DN-114001 on winter infections in free-living elderly subjects: a randomised, controlled pilot study. J Nutr Health Aging 2003; 7: 75–77.
    • (2003) J Nutr Health Aging , vol.7 , pp. 75-77
    • Turchet, P.1    Laurenzano, M.2    Auboiron, S.3
  • 192
    • 4243076298 scopus 로고    scopus 로고
    • Probiotics and prebiotics in the elderly
    • COI: 1:STN:280:DC%2BD2czps1KjtA%3D%3D, PID: 15299153
    • Hamilton-Miller JMT. Probiotics and prebiotics in the elderly. Postgrad Med J 2004;80:447–451.
    • (2004) Postgrad Med J , vol.80 , pp. 447-451
    • Hamilton-Miller, J.M.T.1
  • 193
    • 0035102776 scopus 로고    scopus 로고
    • Probiotic supplementation to enhance natural immunity in the elderly: effects of a newly characterized immunostimulatory strain Lactobacillus rhamnosus HN001 (DR20?) on leucocyte phagocytosis
    • COI: 1:CAS:528:DC%2BD3MXitFajsrw%3D
    • Gill HS, Rutherfurd KJ. Probiotic supplementation to enhance natural immunity in the elderly: effects of a newly characterized immunostimulatory strain Lactobacillus rhamnosus HN001 (DR20?) on leucocyte phagocytosis. Nutr Res 2001; 21: 183–189.
    • (2001) Nutr Res , vol.21 , pp. 183-189
    • Gill, H.S.1    Rutherfurd, K.J.2
  • 194
    • 0035179295 scopus 로고    scopus 로고
    • Enhancement of immunity in the elderly by dietary supplementation with the probiotic Bifidobacterium lactis HN019
    • COI: 1:CAS:528:DC%2BD3MXovVSgtbk%3D, PID: 11722966
    • Gill HS, Rutherfurd KJ, Cross ML et al. Enhancement of immunity in the elderly by dietary supplementation with the probiotic Bifidobacterium lactis HN019. Am J Clin Nutr 2001; 74: 833–839.
    • (2001) Am J Clin Nutr , vol.74 , pp. 833-839
    • Gill, H.S.1    Rutherfurd, K.J.2    Cross, M.L.3
  • 195
    • 77951942306 scopus 로고    scopus 로고
    • Probiotics and immunosenescence: cheese as a carrier
    • COI: 1:CAS:528:DC%2BC3cXms1aqsLw%3D, PID: 20236323
    • Ibrahim F, Ruvio S, Granlund L et al. Probiotics and immunosenescence: cheese as a carrier. FEMS Immunol Med Microbiol 2010; 59: 53–59.
    • (2010) FEMS Immunol Med Microbiol , vol.59 , pp. 53-59
    • Ibrahim, F.1    Ruvio, S.2    Granlund, L.3
  • 196
    • 84862338872 scopus 로고    scopus 로고
    • Probiotic cheese containing Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus NCFM® modifies subpopulations of fecal lactobacilli and Clostridium difficile in the elderly
    • PID: 21264685
    • Lahtinen SJ, Forssten S, Aakko J et al. Probiotic cheese containing Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus NCFM® modifies subpopulations of fecal lactobacilli and Clostridium difficile in the elderly. Age 2012; 34: 133–143.
    • (2012) Age , vol.34 , pp. 133-143
    • Lahtinen, S.J.1    Forssten, S.2    Aakko, J.3
  • 197
    • 33947096460 scopus 로고    scopus 로고
    • Effects of a fermented milk drink containing Lactobacillus casei strain Shirota on the human NK-cell activity
    • COI: 1:CAS:528:DC%2BD2sXisVygtr8%3D, PID: 17311976
    • Takeda K, Okumura K. Effects of a fermented milk drink containing Lactobacillus casei strain Shirota on the human NK-cell activity. J Nutr 2007; 137: 791S–793S.
    • (2007) J Nutr , vol.137 , pp. 791S-793S
    • Takeda, K.1    Okumura, K.2
  • 198
    • 14644432361 scopus 로고    scopus 로고
    • Modulation of natural killer cell activity by supplementation of fermented milk containing Lactobacillus casei in habitual smokers
    • PID: 15749143
    • Morimoto K, Takeshita T, Nanno M et al. Modulation of natural killer cell activity by supplementation of fermented milk containing Lactobacillus casei in habitual smokers. Prev Med 2005; 40: 589–594.
    • (2005) Prev Med , vol.40 , pp. 589-594
    • Morimoto, K.1    Takeshita, T.2    Nanno, M.3
  • 199
    • 0036170747 scopus 로고    scopus 로고
    • Effects of oligosaccharide on the faecal flora and non-specific immune system in elderly people
    • COI: 1:CAS:528:DC%2BD38XhsFSrsbc%3D
    • Guigoz Y, Rochat F, Perruisseau-Carrier G et al. Effects of oligosaccharide on the faecal flora and non-specific immune system in elderly people. Nutr Res 2002; 22: 13–25.
    • (2002) Nutr Res , vol.22 , pp. 13-25
    • Guigoz, Y.1    Rochat, F.2    Perruisseau-Carrier, G.3
  • 200
    • 0030904993 scopus 로고    scopus 로고
    • Effects of inulin and lactose on fecal microflora, microbial activity, and bowel habit in elderly constipated persons
    • COI: 1:STN:280:DyaK2s3nsFKqug%3D%3D, PID: 9129468
    • Kleessen B, Sykura B, Zunft H-J et al. Effects of inulin and lactose on fecal microflora, microbial activity, and bowel habit in elderly constipated persons. Am J Clin Nutr 1997; 65: 1397–1402.
    • (1997) Am J Clin Nutr , vol.65 , pp. 1397-1402
    • Kleessen, B.1    Sykura, B.2    Zunft, H.-J.3
  • 201
    • 55849146633 scopus 로고    scopus 로고
    • Modulation of the fecal microflora profile and immune function by a novel trans-galactooligosaccharide mixture (B-GOS) in healthy elderly volunteers
    • COI: 1:CAS:528:DC%2BD1cXhtlOqu7vP, PID: 18996881
    • Vulevic J, Drakoularakou A, Yaqoob P et al. Modulation of the fecal microflora profile and immune function by a novel trans-galactooligosaccharide mixture (B-GOS) in healthy elderly volunteers. Am J Clin Nutr 2008; 88: 1438–1446.
    • (2008) Am J Clin Nutr , vol.88 , pp. 1438-1446
    • Vulevic, J.1    Drakoularakou, A.2    Yaqoob, P.3
  • 202
    • 38949200638 scopus 로고    scopus 로고
    • Four-week short chain fructo-oligosaccharides ingestion leads to increasing fecal bifidobacteria and cholesterol excretion in healthy elderly volunteers
    • PID: 18053236
    • Bouhnik Y, Achour L, Paineau D et al. Four-week short chain fructo-oligosaccharides ingestion leads to increasing fecal bifidobacteria and cholesterol excretion in healthy elderly volunteers. Nutr J 2007; 6: 42.
    • (2007) Nutr J , vol.6 , pp. 42
    • Bouhnik, Y.1    Achour, L.2    Paineau, D.3
  • 203
    • 47749142021 scopus 로고    scopus 로고
    • The role of bifidobacteria in health
    • Reyed M. The role of bifidobacteria in health. Res J Medicine Med Sci 2000; 2: 14–24.
    • (2000) Res J Medicine Med Sci , vol.2 , pp. 14-24
    • Reyed, M.1
  • 204
    • 12344249654 scopus 로고    scopus 로고
    • Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active Ulcerative Colitis: a randomised controlled pilot trial
    • COI: 1:STN:280:DC%2BD2M%2FitFSrsA%3D%3D, PID: 15647189
    • Furrie E, Macfarlane S, Kennedy A et al. Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active Ulcerative Colitis: a randomised controlled pilot trial. Gut 2005; 54: 242–249.
    • (2005) Gut , vol.54 , pp. 242-249
    • Furrie, E.1    Macfarlane, S.2    Kennedy, A.3
  • 205
    • 34547655340 scopus 로고    scopus 로고
    • High dose probiotic and prebiotic cotherapy for remission induction of active Crohn’s disease
    • Fujimori S, Tatsuguchi A, Gudis K et al. High dose probiotic and prebiotic cotherapy for remission induction of active Crohn’s disease. J Gastroenterol Hepatol 2006; 22: 1199–1204.
    • (2006) J Gastroenterol Hepatol , vol.22 , pp. 1199-1204
    • Fujimori, S.1    Tatsuguchi, A.2    Gudis, K.3
  • 206
    • 84866497902 scopus 로고    scopus 로고
    • Gut microbiota of healthy elderly NSAID users is selectively modified with the administration of Lactobacillus acidophilus NCFM and lactitol
    • PID: 21853265
    • Björklund M, Ouwehand AC, Forssten SD et al. Gut microbiota of healthy elderly NSAID users is selectively modified with the administration of Lactobacillus acidophilus NCFM and lactitol. Age 2012; 34: 987–999.
    • (2012) Age , vol.34 , pp. 987-999
    • Björklund, M.1    Ouwehand, A.C.2    Forssten, S.D.3
  • 207
    • 66849131399 scopus 로고    scopus 로고
    • Influence of a combination of Lactobacillus acidophilus NCFM and lactitol on healthy elderly: intestinal and immune parameters
    • COI: 1:CAS:528:DC%2BD1MXhvVWku74%3D, PID: 18634707
    • Ouwehand AC, Tiihonen K, Saarinen M et al. Influence of a combination of Lactobacillus acidophilus NCFM and lactitol on healthy elderly: intestinal and immune parameters. Br J Nutr 2009; 101: 367–375.
    • (2009) Br J Nutr , vol.101 , pp. 367-375
    • Ouwehand, A.C.1    Tiihonen, K.2    Saarinen, M.3
  • 208
    • 11144238567 scopus 로고    scopus 로고
    • Microbiological effects of consuming a synbiotic containing Bifidobacterium bifidum, Bifidobacterium lactis. and oligofructose in elderly persons, determined by real-time polymerase chain reaction and counting of viable bacteria
    • PID: 15614689
    • Bartosch S, Woodmansey EJ, Paterson JCM et al. Microbiological effects of consuming a synbiotic containing Bifidobacterium bifidum, Bifidobacterium lactis. and oligofructose in elderly persons, determined by real-time polymerase chain reaction and counting of viable bacteria. Clin infect Dis 2005; 40: 28–37.
    • (2005) Clin infect Dis , vol.40 , pp. 28-37
    • Bartosch, S.1    Woodmansey, E.J.2    Paterson, J.C.M.3
  • 209
    • 0141988697 scopus 로고    scopus 로고
    • Effects of the consumption of Bifidobacterium lactis HN019 (DR10 sup TM/sup) and galacto-oligosaccharides on the microflora of the gastrointestinal tract in human subjects
    • COI: 1:CAS:528:DC%2BD3sXovVGnsr8%3D
    • Gopal PK, Prasad J, Gill HS. Effects of the consumption of Bifidobacterium lactis HN019 (DR10 sup TM/sup) and galacto-oligosaccharides on the microflora of the gastrointestinal tract in human subjects. Nutr Res 2003; 23: 1313–1328.
    • (2003) Nutr Res , vol.23 , pp. 1313-1328
    • Gopal, P.K.1    Prasad, J.2    Gill, H.S.3
  • 210
    • 33745183455 scopus 로고    scopus 로고
    • Melatonin, immune function and aging
    • COI: 1:STN:280:DC%2BD28%2Fhtlejsg%3D%3D, PID: 16316470
    • Srinivasan V, Maestroni G, Cardinali D et al. Melatonin, immune function and aging. Immun Ageing 2005; 2: 17.
    • (2005) Immun Ageing , vol.2 , pp. 17
    • Srinivasan, V.1    Maestroni, G.2    Cardinali, D.3
  • 211
    • 79958865823 scopus 로고    scopus 로고
    • Antimicrobial prescribing in European nursing homes
    • COI: 1:CAS:528:DC%2BC3MXnsFWks7s%3D, PID: 21596722
    • McClean P, Hughes C, Tunney M et al. Antimicrobial prescribing in European nursing homes. J Antimicrob Chemother 2011; 66: 1609–1616.
    • (2011) J Antimicrob Chemother , vol.66 , pp. 1609-1616
    • McClean, P.1    Hughes, C.2    Tunney, M.3
  • 213
    • 0025020507 scopus 로고
    • Multiple-dose pharmacokinetics of concurrent oral ciprofloxacin and rifampin therapy in elderly patients
    • COI: 1:STN:280:DyaK3c3ktVOjsA%3D%3D, PID: 2185691
    • Chandler M, Toler S, Rapp R et al. Multiple-dose pharmacokinetics of concurrent oral ciprofloxacin and rifampin therapy in elderly patients. Antimicrob Agents Chemother 1990; 34: 442–447.
    • (1990) Antimicrob Agents Chemother , vol.34 , pp. 442-447
    • Chandler, M.1    Toler, S.2    Rapp, R.3
  • 214
    • 0022411345 scopus 로고
    • Pharmacokinetics of the trimethoprim-sulphamethoxazole combination in the elderly
    • COI: 1:CAS:528:DyaL28XhtVWru78%3D, PID: 3879182
    • Varoquaux O, Lajoie D, Gobert C et al. Pharmacokinetics of the trimethoprim-sulphamethoxazole combination in the elderly. Br J Clin Pharmacol 1985; 20: 575–581.
    • (1985) Br J Clin Pharmacol , vol.20 , pp. 575-581
    • Varoquaux, O.1    Lajoie, D.2    Gobert, C.3
  • 215
    • 0030947798 scopus 로고    scopus 로고
    • Use of aminoglycosides in elderly patients
    • PID: 9108987
    • Mörike K, Schwab M, Klotz U. Use of aminoglycosides in elderly patients. Drugs Aging 1997; 10: 259–277.
    • (1997) Drugs Aging , vol.10 , pp. 259-277
    • Mörike, K.1    Schwab, M.2    Klotz, U.3
  • 216
    • 33748160502 scopus 로고    scopus 로고
    • Mesalazine and/or Lactobacillus casei in preventing recurrence of symptomatic uncomplicated diverticular disease of the colon: a prospective, randomized, open-label study
    • PID: 16633103
    • Tursi A, Brandimarte G, Giorgetti GM et al. Mesalazine and/or Lactobacillus casei in preventing recurrence of symptomatic uncomplicated diverticular disease of the colon: a prospective, randomized, open-label study. J Clin Gastroenterol 2006; 40: 312–316.
    • (2006) J Clin Gastroenterol , vol.40 , pp. 312-316
    • Tursi, A.1    Brandimarte, G.2    Giorgetti, G.M.3
  • 217
    • 33645455337 scopus 로고    scopus 로고
    • Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease
    • PID: 16635227
    • McFarland LV. Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease. Am J Gastroenterol 2006; 101: 812–822.
    • (2006) Am J Gastroenterol , vol.101 , pp. 812-822
    • McFarland, L.V.1
  • 218
    • 35148864701 scopus 로고    scopus 로고
    • Improvement of nutritional status and incidence of infection in hospitalised, enterally fed elderly by feeding of fermented milk containing probiotic Lactobacillus johnsonii La1 (NCC533)
    • COI: 1:CAS:528:DC%2BD2sXhtlSktLfI, PID: 17617944
    • Fukushima Y, Miyaguchi S, Yamano T et al. Improvement of nutritional status and incidence of infection in hospitalised, enterally fed elderly by feeding of fermented milk containing probiotic Lactobacillus johnsonii La1 (NCC533). Br J Nutr 2007; 98: 969–977.
    • (2007) Br J Nutr , vol.98 , pp. 969-977
    • Fukushima, Y.1    Miyaguchi, S.2    Yamano, T.3
  • 219
    • 34447630803 scopus 로고    scopus 로고
    • Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial
    • PID: 17604300
    • Hickson M, D’Souza AL, Muthu N et al. Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial. BMJ 2007; 335: 80.
    • (2007) BMJ , vol.335 , pp. 80
    • Hickson, M.1    D’Souza, A.L.2    Muthu, N.3
  • 220
    • 50949100435 scopus 로고    scopus 로고
    • Therapeutic effect of Lactobacillus acidophilus-SDC 2012, 2013 in patients with irritable bowel syndrome
    • PID: 18274900
    • Sinn DH, Song JH, Kim HJ et al. Therapeutic effect of Lactobacillus acidophilus-SDC 2012, 2013 in patients with irritable bowel syndrome. Dig Dis Sci 2008; 53: 2714–2718.
    • (2008) Dig Dis Sci , vol.53 , pp. 2714-2718
    • Sinn, D.H.1    Song, J.H.2    Kim, H.J.3
  • 221
    • 69249209646 scopus 로고    scopus 로고
    • A probiotic fermented dairy drink improves antibody response to influenza vaccination in the elderly in two randomised controlled trials
    • COI: 1:CAS:528:DC%2BD1MXhtVKntrvN, PID: 19615959
    • Boge T, Rémigy M, Vaudaine S et al. A probiotic fermented dairy drink improves antibody response to influenza vaccination in the elderly in two randomised controlled trials. Vaccine 2009; 27: 5677–5684.
    • (2009) Vaccine , vol.27 , pp. 5677-5684
    • Boge, T.1    Rémigy, M.2    Vaudaine, S.3
  • 222
    • 68749086014 scopus 로고    scopus 로고
    • Effect of a synbiotic food consumption on human gut metabolic profiles evaluated by sup 1/sup H Nuclear Magnetic Resonance spectroscopy
    • COI: 1:CAS:528:DC%2BD1MXhtVentLvO, PID: 19446905
    • Ndagijimana M, Laghi L, Vitali B et al. Effect of a synbiotic food consumption on human gut metabolic profiles evaluated by sup 1/sup H Nuclear Magnetic Resonance spectroscopy. Int J Food Microbiol 2009; 134: 147–153.
    • (2009) Int J Food Microbiol , vol.134 , pp. 147-153
    • Ndagijimana, M.1    Laghi, L.2    Vitali, B.3
  • 223
    • 77951163668 scopus 로고    scopus 로고
    • Probiotics in diverticular disease of the colon: an open label study
    • PID: 20361072
    • Lamiki P, Tsuchiya J, Pathak S et al. Probiotics in diverticular disease of the colon: an open label study. J Gastrointestin Liver Dis 2010; 19: 31–36.
    • (2010) J Gastrointestin Liver Dis , vol.19 , pp. 31-36
    • Lamiki, P.1    Tsuchiya, J.2    Pathak, S.3
  • 224
    • 75549091605 scopus 로고    scopus 로고
    • Consumption of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 reduces the duration of respiratory infections in the elderly in a randomised controlled trial
    • COI: 1:CAS:528:DC%2BD1MXhs1Smt73N, PID: 19747410
    • Guillemard E, Tondu F, Lacoin F et al. Consumption of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 reduces the duration of respiratory infections in the elderly in a randomised controlled trial. Br J Nutr 2010; 103: 58–68.
    • (2010) Br J Nutr , vol.103 , pp. 58-68
    • Guillemard, E.1    Tondu, F.2    Lacoin, F.3
  • 225
    • 77955399038 scopus 로고    scopus 로고
    • Effects of Bifidobacterium longum BB536 administration on influenza infection, influenza vaccine antibody titer and cell-mediated immunity in the elderly
    • COI: 1:CAS:528:DC%2BC3cXnt1Gms7w%3D, PID: 20460726
    • Namba K, Hatano M, Yaeshima T et al. Effects of Bifidobacterium longum BB536 administration on influenza infection, influenza vaccine antibody titer and cell-mediated immunity in the elderly. Biosci Biotechnol Biochem 2010; 74: 939–945.
    • (2010) Biosci Biotechnol Biochem , vol.74 , pp. 939-945
    • Namba, K.1    Hatano, M.2    Yaeshima, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.