Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 20, 2010, Pages 9352-9357

  Rea, Mary C ^a,b   Sit, Clarissa S ^c   Clayton, Evelyn ^a,b   O'Connor, Paula M ^a,b   Whittal, Randy M ^c   Zheng, Jing ^c   Vederas, John C ^c   Ross, R Paul ^a,b   Hill, Colin ^b,d  

^a TEAGASC FOOD RESEARCH CENTRE   (Ireland)

^b UNIVERSITY COLLEGE CORK   (Ireland)

^c UNIVERSITY OF ALBERTA   (Canada)

^d UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Clostridium difficile associated disease; NMR; Peptide; Posttranslational modifications; Two component bacteriocin

Indexed keywords

BACTERIOCIN; CARBON; CYSTEINE; METRONIDAZOLE; PROBIOTIC AGENT; S ADENOSYLMETHIONINE; THURICIN;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS THURINGIENSIS; BACTERIAL STRAIN; BACTERIUM CULTURE; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; GENE CLUSTER; HUMAN; LISTERIA MONOCYTOGENES; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ISOLATION; PROTEIN PROCESSING; PROTEIN PURIFICATION; SEQUENCE ANALYSIS; TANDEM MASS SPECTROMETRY;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACILLUS THURINGIENSIS; BACTERIOCINS; CLOSTRIDIUM DIFFICILE; FECES; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN PROCESSING, POST-TRANSLATIONAL; S-ADENOSYLMETHIONINE; SEQUENCE ANALYSIS, PROTEIN; TANDEM MASS SPECTROMETRY;

BACILLUS THURINGIENSIS; BACTERIA (MICROORGANISMS); CLOSTRIDIUM DIFFICILE;

EID: 77952679997     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0913554107     Document Type: Article

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