Axonal and Schwann cell BACE1 is equally required for remyelination of peripheral nerves

Journal of Neuroscience

Volumn 35, Issue 9, 2015, Pages 3806-3814

  Hu, Xiangyou ^a,b   Hu, Jinxuan ^a   Dai, Lu ^a   Trapp, Bruce ^a   Yan, Riqiang ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

BACE1; Cell autonomy; Neuregulin; Remyelination; Sciatic nerve transplantation; Secretase

Indexed keywords

BETA SECRETASE 1; CYCLOSPORIN A; NEU DIFFERENTIATION FACTOR; ASPARTIC PROTEINASE; BACE1 PROTEIN, MOUSE; NRG1 PROTEIN, MOUSE; SECRETASE;

ADULT; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; GENETIC TRANSCRIPTION; IMMUNOSUPPRESSIVE TREATMENT; IN SITU HYBRIDIZATION; MALE; MOUSE; MYELIN SHEATH; MYELIN SHEATH THICKNESS; NERVE FIBER; NERVE FUNCTION; NERVE INJURY; NERVE TRANSPLANTATION; NERVOUS SYSTEM PARAMETERS; NONHUMAN; PERIPHERAL NERVE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOIMMUNOPRECIPITATION; REMYELINIZATION; SCHWANN CELL; SCIATIC NERVE; WESTERN BLOTTING; ANIMAL; AXON; BIOSYNTHESIS; C57BL MOUSE; ENZYMOLOGY; GENETICS; KNOCKOUT MOUSE; NERVE REGENERATION; NERVOUS TISSUE; PHYSIOLOGY; TRANSPLANTATION;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; AXONS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELIN SHEATH; NERVE REGENERATION; NERVE TISSUE; NEUREGULIN-1; PERIPHERAL NERVES; SCHWANN CELLS; SCIATIC NERVE;

EID: 84924785843     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5207-14.2015     Document Type: Article

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