-
1
-
-
0029933153
-
The role of APP processing and trafficking pathways in the formation of amyloid β-protein
-
Selkoe, D. J., Yamazaki, T., Citron, M., Podlisny, M. B., Koo, E. H., Teplow, D. B., and Haass, C. (1996) The role of APP processing and trafficking pathways in the formation of amyloid β-protein. Ann. N.Y. Acad. Sci. 777, 57-64
-
(1996)
Ann. N.Y. Acad. Sci.
, vol.777
, pp. 57-64
-
-
Selkoe, D.J.1
Yamazaki, T.2
Citron, M.3
Podlisny, M.B.4
Koo, E.H.5
Teplow, D.B.6
Haass, C.7
-
2
-
-
0036548070
-
β-Secretase, Notch, Aβ and Alzheimer's disease. Where do the presenilins fit in?
-
Sisodia, S. S., and St George-Hyslop, P. H. (2002) β-Secretase, Notch, Aβ and Alzheimer's disease. Where do the presenilins fit in? Nat. Rev. Neurosci. 3, 281-290
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 281-290
-
-
Sisodia, S.S.1
St George-Hyslop, P.H.2
-
3
-
-
1442264828
-
Take five. BACE and the β-secretase quartet conduct Alzheimer's amyloid β-peptide generation
-
Haass, C. (2004) Take five. BACE and the β-secretase quartet conduct Alzheimer's amyloid β-peptide generation. EMBO J. 23, 483-488
-
(2004)
EMBO J.
, vol.23
, pp. 483-488
-
-
Haass, C.1
-
4
-
-
0033382226
-
Identification of a novel aspartic protease (Asp 2) as β-secretase
-
Hussain, I., Powell, D., Howlett, D. R., Tew, D. G., Meek, T. D., Chapman, C., Gloger, I. S., Murphy, K. E., Southan, C. D., Ryan, D. M., Smith, T. S., Simmons, D. L., Walsh, F. S., Dingwall, C., and Christie, G. (1999) Identification of a novel aspartic protease (Asp 2) as β-secretase. Mol. Cell Neurosci. 14, 419-427
-
(1999)
Mol. Cell Neurosci.
, vol.14
, pp. 419-427
-
-
Hussain, I.1
Powell, D.2
Howlett, D.R.3
Tew, D.G.4
Meek, T.D.5
Chapman, C.6
Gloger, I.S.7
Murphy, K.E.8
Southan, C.D.9
Ryan, D.M.10
Smith, T.S.11
Simmons, D.L.12
Walsh, F.S.13
Dingwall, C.14
Christie, G.15
-
5
-
-
0033595706
-
β-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P., Teplow, D. B., Ross, S., Amarante, P., Loeloff, R., Luo, Y., Fisher, S., Fuller, J., Edenson, S., Lile, J., Jarosinski, M. A., Biere, A. L., Curran, E., Burgess, T., Louis, J. C., Collins, F., Treanor, J., Rogers, G., and Citron, M. (1999) β-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 286, 735-741
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
6
-
-
0033518264
-
Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity
-
Yan, R., Bienkowski, M. J., Shuck, M. E., Miao, H., Tory, M. C., Pauley, A. M., Brashier, J. R., Stratman, N. C., Mathews, W. R., Buhl, A. E., Carter, D. B., Tomasselli, A. G., Parodi, L. A., Heinrikson, R. L., and Gurney, M. E. (1999) Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity. Nature 402, 533-537
-
(1999)
Nature
, vol.402
, pp. 533-537
-
-
Yan, R.1
Bienkowski, M.J.2
Shuck, M.E.3
Miao, H.4
Tory, M.C.5
Pauley, A.M.6
Brashier, J.R.7
Stratman, N.C.8
Mathews, W.R.9
Buhl, A.E.10
Carter, D.B.11
Tomasselli, A.G.12
Parodi, L.A.13
Heinrikson, R.L.14
Gurney, M.E.15
-
7
-
-
0033518251
-
Purification and cloning of amyloid precursor protein β-secretase from human brain
-
Sinha, S., Anderson, J. P., Barbour, R., Basi, G. S., Caccavello, R., Davis, D., Doan, M., Dovey, H. F., Frigon, N., Hong, J., Jacobson-Croak, K., Jewett, N., Keim, P., Knops, J., Lieberburg, I., Power, M., Tan, H., Tatsuno, G., Tung, J., Schenk, D., Seubert, P., Suomensaari, S. M., Wang, S., Walker, D., Zhao, J., McConlogue, L., and John, V. (1999) Purification and cloning of amyloid precursor protein β-secretase from human brain. Nature 402, 537-540
-
(1999)
Nature
, vol.402
, pp. 537-540
-
-
Sinha, S.1
Anderson, J.P.2
Barbour, R.3
Basi, G.S.4
Caccavello, R.5
Davis, D.6
Doan, M.7
Dovey, H.F.8
Frigon, N.9
Hong, J.10
Jacobson-Croak, K.11
Jewett, N.12
Keim, P.13
Knops, J.14
Lieberburg, I.15
Power, M.16
Tan, H.17
Tatsuno, G.18
Tung, J.19
Schenk, D.20
Seubert, P.21
Suomensaari, S.M.22
Wang, S.23
Walker, D.24
Zhao, J.25
McConlogue, L.26
John, V.27
more..
-
8
-
-
0034652309
-
Human aspartic protease memapsin 2 cleaves the β-secretase site of β-amyloid precursor protein
-
Lin, X., Koelsch, G., Wu, S., Downs, D., Dashti, A., and Tang, J. (2000) Human aspartic protease memapsin 2 cleaves the β-secretase site of β-amyloid precursor protein. Proc. Natl. Acad. Sci. U.S.A. 97, 1456-1460
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 1456-1460
-
-
Lin, X.1
Koelsch, G.2
Wu, S.3
Downs, D.4
Dashti, A.5
Tang, J.6
-
9
-
-
4644229581
-
Design and development of BACE-1 inhibitors
-
Cumming, J. N., Iserloh, U., and Kennedy, M. E. (2004) Design and development of BACE-1 inhibitors. Curr. Opin. Drug Discov. Devel. 7, 536-556
-
(2004)
Curr. Opin. Drug Discov. Devel.
, vol.7
, pp. 536-556
-
-
Cumming, J.N.1
Iserloh, U.2
Kennedy, M.E.3
-
10
-
-
84866291339
-
The membrane-bound aspartyl protease BACE1. Molecular and functional properties in Alzheimer's disease and beyond
-
Dislich, B., and Lichtenthaler, S. F. (2012) The membrane-bound aspartyl protease BACE1. Molecular and functional properties in Alzheimer's disease and beyond. Front. Physiol. 3, 8
-
(2012)
Front. Physiol.
, vol.3
, pp. 8
-
-
Dislich, B.1
Lichtenthaler, S.F.2
-
11
-
-
77956048697
-
Inhibition of BACE1 for therapeutic use in Alzheimer's disease
-
Luo, X., and Yan, R. (2010) Inhibition of BACE1 for therapeutic use in Alzheimer's disease. Int. J. Clin. Exp. Pathol. 3, 618-628
-
(2010)
Int. J. Clin. Exp. Pathol.
, vol.3
, pp. 618-628
-
-
Luo, X.1
Yan, R.2
-
12
-
-
84655162702
-
Developing β-secretase inhibitors for treatment of Alzheimer's disease
-
Ghosh, A. K., Brindisi, M., and Tang, J. (2012) Developing β-secretase inhibitors for treatment of Alzheimer's disease. J. Neurochem. 120, 71-83
-
(2012)
J. Neurochem.
, vol.120
, pp. 71-83
-
-
Ghosh, A.K.1
Brindisi, M.2
Tang, J.3
-
13
-
-
70350455062
-
The β-secretase enzyme BACE in health and Alzheimer's disease. Regulation, cell biology, function, and therapeutic potential
-
Vassar, R., Kovacs, D. M., Yan, R., and Wong, P. C. (2009) The β-secretase enzyme BACE in health and Alzheimer's disease. Regulation, cell biology, function, and therapeutic potential. J. Neurosci. 29, 12787-12794
-
(2009)
J. Neurosci.
, vol.29
, pp. 12787-12794
-
-
Vassar, R.1
Kovacs, D.M.2
Yan, R.3
Wong, P.C.4
-
14
-
-
84857914247
-
B-site APP-cleaving enzyme 1 trafficking and Alzheimer's disease pathogenesis
-
Tan, J., and Evin, G. (2012) B-site APP-cleaving enzyme 1 trafficking and Alzheimer's disease pathogenesis. J. Neurochem. 120, 869-880
-
(2012)
J. Neurochem.
, vol.120
, pp. 869-880
-
-
Tan, J.1
Evin, G.2
-
16
-
-
79953297068
-
BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin
-
Finan, G. M., Okada, H., and Kim, T. W. (2011) BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin. J. Biol. Chem. 286, 12602-12616
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 12602-12616
-
-
Finan, G.M.1
Okada, H.2
Kim, T.W.3
-
17
-
-
84862907635
-
VPS35 haploinsufficiency increases Alzheimer's disease neuropathology
-
Wen, L., Tang, F. L., Hong, Y., Luo, S. W., Wang, C. L., He, W., Shen, C., Jung, J. U., Xiong, F., Lee, D. H., Zhang, Q. G., Brann, D., Kim, T. W., Yan, R., Mei, L., and Xiong, W. C. (2011) VPS35 haploinsufficiency increases Alzheimer's disease neuropathology. J. Cell Biol. 195, 765-779
-
(2011)
J. Cell Biol.
, vol.195
, pp. 765-779
-
-
Wen, L.1
Tang, F.L.2
Hong, Y.3
Luo, S.W.4
Wang, C.L.5
He, W.6
Shen, C.7
Jung, J.U.8
Xiong, F.9
Lee, D.H.10
Zhang, Q.G.11
Brann, D.12
Kim, T.W.13
Yan, R.14
Mei, L.15
Xiong, W.C.16
-
18
-
-
34249734831
-
Depletion of GGA3 stabilizes BACE and enhances β-secretase activity
-
Tesco, G., Koh, Y. H., Kang, E. L., Cameron, A. N., Das, S., Sena-Esteves, M., Hiltunen, M., Yang, S. H., Zhong, Z., Shen, Y., Simpkins, J. W., and Tanzi, R. E. (2007) Depletion of GGA3 stabilizes BACE and enhances β-secretase activity. Neuron 54, 721-737
-
(2007)
Neuron
, vol.54
, pp. 721-737
-
-
Tesco, G.1
Koh, Y.H.2
Kang, E.L.3
Cameron, A.N.4
Das, S.5
Sena-Esteves, M.6
Hiltunen, M.7
Yang, S.H.8
Zhong, Z.9
Shen, Y.10
Simpkins, J.W.11
Tanzi, R.E.12
-
19
-
-
77954945651
-
Ubiquitin regulates GGA3-mediated degradation of BACE1
-
Kang, E. L., Cameron, A. N., Piazza, F., Walker, K. R., and Tesco, G. (2010) Ubiquitin regulates GGA3-mediated degradation of BACE1. J. Biol. Chem. 285, 24108-24119
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 24108-24119
-
-
Kang, E.L.1
Cameron, A.N.2
Piazza, F.3
Walker, K.R.4
Tesco, G.5
-
20
-
-
15744380393
-
GGA proteins mediate the recycling pathway of memapsin 2 (BACE)
-
He, X., Li, F., Chang, W. P., and Tang, J. (2005) GGA proteins mediate the recycling pathway of memapsin 2 (BACE). J. Biol. Chem. 280, 11696 -11703
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 11696-11703
-
-
He, X.1
Li, F.2
Chang, W.P.3
Tang, J.4
-
21
-
-
20444377260
-
GGA proteins regulate retrograde transport of BACE1 from endosomes to the trans-Golgi network
-
Wahle, T., Prager, K., Raffler, N., Haass, C., Famulok, M., and Walter, J. (2005) GGA proteins regulate retrograde transport of BACE1 from endosomes to the trans-Golgi network. Mol. Cell Neurosci. 29, 453-461
-
(2005)
Mol. Cell Neurosci.
, vol.29
, pp. 453-461
-
-
Wahle, T.1
Prager, K.2
Raffler, N.3
Haass, C.4
Famulok, M.5
Walter, J.6
-
22
-
-
79955944449
-
Decreased expression of GGA3 protein in Alzheimer's disease frontal cortex and increased codistribution of BACE with the amyloid precursor protein
-
Santosa, C., Rasche, S., Barakat, A., Bellingham, S. A., Ho, M., Tan, J., Hill, A. F., Masters, C. L., McLean, C., and Evin, G. (2011) Decreased expression of GGA3 protein in Alzheimer's disease frontal cortex and increased codistribution of BACE with the amyloid precursor protein. Neurobiol. Dis. 43, 176-183
-
(2011)
Neurobiol. Dis.
, vol.43
, pp. 176-183
-
-
Santosa, C.1
Rasche, S.2
Barakat, A.3
Bellingham, S.A.4
Ho, M.5
Tan, J.6
Hill, A.F.7
Masters, C.L.8
McLean, C.9
Evin, G.10
-
23
-
-
4644357534
-
Reticulon family members modulate BACE1 activity and amyloid- peptide generation
-
He, W., Lu, Y., Qahwash, I., Hu, X. Y., Chang, A., and Yan, R. (2004) Reticulon family members modulate BACE1 activity and amyloid- peptide generation. Nat. Med. 10, 959-965
-
(2004)
Nat. Med.
, vol.10
, pp. 959-965
-
-
He, W.1
Lu, Y.2
Qahwash, I.3
Hu, X.Y.4
Chang, A.5
Yan, R.6
-
24
-
-
33748755837
-
Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid β-protein
-
Murayama, K. S., Kametani, F., Saito, S., Kume, H., Akiyama, H., and Araki, W. (2006) Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid β-protein. Eur. J. Neurosci. 24, 1237-1244
-
(2006)
Eur. J. Neurosci.
, vol.24
, pp. 1237-1244
-
-
Murayama, K.S.1
Kametani, F.2
Saito, S.3
Kume, H.4
Akiyama, H.5
Araki, W.6
-
25
-
-
67651154309
-
Reduced amyloid deposition in mice overexpressing RTN3 is adversely affected by preformed dystrophic neurites
-
Shi, Q., Prior, M., He, W., Tang, X., Hu, X., and Yan, R. (2009) Reduced amyloid deposition in mice overexpressing RTN3 is adversely affected by preformed dystrophic neurites. J. Neurosci. 29, 9163-9173
-
(2009)
J. Neurosci.
, vol.29
, pp. 9163-9173
-
-
Shi, Q.1
Prior, M.2
He, W.3
Tang, X.4
Hu, X.5
Yan, R.6
-
26
-
-
33646577429
-
Reticulon proteins. Emerging players in neurodegenerative diseases
-
Yan, R., Shi, Q., Hu, X., and Zhou, X. (2006) Reticulon proteins. Emerging players in neurodegenerative diseases. Cell Mol. Life Sci. 63, 877-889
-
(2006)
Cell Mol. Life Sci.
, vol.63
, pp. 877-889
-
-
Yan, R.1
Shi, Q.2
Hu, X.3
Zhou, X.4
-
27
-
-
40449124075
-
The reticulons. A family of proteins with diverse functions
-
Yang, Y. S., and Strittmatter, S. M. (2007) The reticulons. A family of proteins with diverse functions. Genome Biol. 8, 234
-
(2007)
Genome Biol.
, vol.8
, pp. 234
-
-
Yang, Y.S.1
Strittmatter, S.M.2
-
28
-
-
0038799728
-
A reticular rhapsody. Phylogenic evolution and nomenclature of the RTN/Nogo gene family
-
Oertle, T., Klinger, M., Stuermer, C. A., and Schwab, M. E. (2003) A reticular rhapsody. Phylogenic evolution and nomenclature of the RTN/Nogo gene family. FASEB J. 17, 1238-1247
-
(2003)
FASEB J.
, vol.17
, pp. 1238-1247
-
-
Oertle, T.1
Klinger, M.2
Stuermer, C.A.3
Schwab, M.E.4
-
29
-
-
14044257857
-
Nogo signaling and non-physical injuryinduced nervous system pathology
-
Teng, F. Y., and Tang, B. L. (2005) Nogo signaling and non-physical injuryinduced nervous system pathology. J. Neurosci. Res. 79, 273-278
-
(2005)
J. Neurosci. Res.
, vol.79
, pp. 273-278
-
-
Teng, F.Y.1
Tang, B.L.2
-
30
-
-
33847164931
-
Two hydrophobic segments of the RTN1 family determine the ER localization and retention
-
Iwahashi, J., Hamada, N., and Watanabe, H. (2007) Two hydrophobic segments of the RTN1 family determine the ER localization and retention. Biochem. Biophys. Res. Commun. 355, 508-512
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.355
, pp. 508-512
-
-
Iwahashi, J.1
Hamada, N.2
Watanabe, H.3
-
31
-
-
32044445021
-
A class of membrane proteins shaping the tubular endoplasmic reticulum
-
Voeltz, G. K., Prinz, W. A., Shibata, Y., Rist, J. M., and Rapoport, T. A. (2006) A class of membrane proteins shaping the tubular endoplasmic reticulum. Cell 124, 573-586
-
(2006)
Cell
, vol.124
, pp. 573-586
-
-
Voeltz, G.K.1
Prinz, W.A.2
Shibata, Y.3
Rist, J.M.4
Rapoport, T.A.5
-
32
-
-
35748960521
-
The membrane topology of RTN3 and its effect on binding of RTN3 to BACE1
-
He, W., Shi, Q., Hu, X., and Yan, R. (2007) The membrane topology of RTN3 and its effect on binding of RTN3 to BACE1. J. Biol. Chem. 282, 29144-29151
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 29144-29151
-
-
He, W.1
Shi, Q.2
Hu, X.3
Yan, R.4
-
33
-
-
33749246089
-
Mapping of interaction domains mediating binding between BACE1 and RTN/Nogo proteins
-
He, W., Hu, X., Shi, Q., Zhou, X., Lu, Y., Fisher, C., and Yan, R. (2006) Mapping of interaction domains mediating binding between BACE1 and RTN/Nogo proteins. J. Mol. Biol. 363, 625-634
-
(2006)
J. Mol. Biol.
, vol.363
, pp. 625-634
-
-
He, W.1
Hu, X.2
Shi, Q.3
Zhou, X.4
Lu, Y.5
Fisher, C.6
Yan, R.7
-
34
-
-
70449379429
-
The two-hydrophobic domain tertiary structure of reticulon proteins is critical for modulation of β-secretase BACE1
-
Kume, H., Murayama, K. S., and Araki, W. (2009) The two-hydrophobic domain tertiary structure of reticulon proteins is critical for modulation of β-secretase BACE1. J. Neurosci. Res. 87, 2963-2972
-
(2009)
J. Neurosci. Res.
, vol.87
, pp. 2963-2972
-
-
Kume, H.1
Murayama, K.S.2
Araki, W.3
-
35
-
-
65549143774
-
The occurrence of aging-dependent reticulon 3 immunoreactive dystrophic neurites decreases cognitive function
-
Shi, Q., Hu, X., Prior, M., and Yan, R. (2009) The occurrence of aging-dependent reticulon 3 immunoreactive dystrophic neurites decreases cognitive function. J. Neurosci. 29, 5108-5115
-
(2009)
J. Neurosci.
, vol.29
, pp. 5108-5115
-
-
Shi, Q.1
Hu, X.2
Prior, M.3
Yan, R.4
-
36
-
-
84873682841
-
Reduction of β-amyloid accumulation by reticulon 3 in transgenic mice
-
Araki, W., Oda, A., Motoki, K., Hattori, K., Itoh, M., Yuasa, S., Konishi, Y., Shin, R. W., Tamaoka, A., and Ogino, K. (2012) Reduction of β-amyloid accumulation by reticulon 3 in transgenic mice. Curr. Alzheimer Res. 10, 135-142
-
(2012)
Curr. Alzheimer Res.
, vol.10
, pp. 135-142
-
-
Araki, W.1
Oda, A.2
Motoki, K.3
Hattori, K.4
Itoh, M.5
Yuasa, S.6
Konishi, Y.7
Shin, R.W.8
Tamaoka, A.9
Ogino, K.10
-
37
-
-
34948899795
-
NOGO is increased and binds to BACE1 in sporadic inclusion-body myositis and in A PP-overexpressing cultured human muscle fibers
-
Wojcik, S., Engel, W. K., Yan, R., McFerrin, J., and Askanas, V. (2007) NOGO is increased and binds to BACE1 in sporadic inclusion-body myositis and in A PP-overexpressing cultured human muscle fibers. Acta Neuropathol. 114, 517-526
-
(2007)
Acta Neuropathol.
, vol.114
, pp. 517-526
-
-
Wojcik, S.1
Engel, W.K.2
Yan, R.3
McFerrin, J.4
Askanas, V.5
-
38
-
-
84878388997
-
Diabetes-induced central neuritic dystrophy and cognitive deficits are associated with the formation of oligomeric reticulon-3 via oxidative stress
-
Zhao, B., Pan, B. S., Shen, S. W., Sun, X., Hou, Z. Z., Yan, R., and Sun, F. Y. (2013) Diabetes-induced central neuritic dystrophy and cognitive deficits are associated with the formation of oligomeric reticulon-3 via oxidative stress. J. Biol. Chem. 288, 15590-15599
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 15590-15599
-
-
Zhao, B.1
Pan, B.S.2
Shen, S.W.3
Sun, X.4
Hou, Z.Z.5
Yan, R.6
Sun, F.Y.7
-
39
-
-
77954087430
-
RTN/Nogo in forming Alzheimer's neuritic plaques
-
Prior, M., Shi, Q., Hu, X., He, W., Levey, A., and Yan, R. (2010) RTN/Nogo in forming Alzheimer's neuritic plaques. Neurosci. Biobehav. Rev. 34, 1201-1206
-
(2010)
Neurosci. Biobehav. Rev.
, vol.34
, pp. 1201-1206
-
-
Prior, M.1
Shi, Q.2
Hu, X.3
He, W.4
Levey, A.5
Yan, R.6
-
40
-
-
34250019939
-
Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities
-
Hu, X., Shi, Q., Zhou, X., He, W., Yi, H., Yin, X., Gearing, M., Levey, A., and Yan, R. (2007) Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities. EMBO J. 26, 2755-2767
-
(2007)
EMBO J.
, vol.26
, pp. 2755-2767
-
-
Hu, X.1
Shi, Q.2
Zhou, X.3
He, W.4
Yi, H.5
Yin, X.6
Gearing, M.7
Levey, A.8
Yan, R.9
-
41
-
-
80455143668
-
Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis
-
Pidoux, G., Witczak, O., Jarnæss, E., Myrvold, L., Urlaub, H., Stokka, A. J., Küntziger, T., and Taskén, K. (2011) Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis. EMBO J. 30, 4371-4386
-
(2011)
EMBO J.
, vol.30
, pp. 4371-4386
-
-
Pidoux, G.1
Witczak, O.2
Jarnæss, E.3
Myrvold, L.4
Urlaub, H.5
Stokka, A.J.6
Küntziger, T.7
Taskén, K.8
-
42
-
-
49649084487
-
The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum
-
Shibata, Y., Voss, C., Rist, J. M., Hu, J., Rapoport, T. A., Prinz, W. A., and Voeltz, G. K. (2008) The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum. J. Biol. Chem. 283, 18892-18904
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 18892-18904
-
-
Shibata, Y.1
Voss, C.2
Rist, J.M.3
Hu, J.4
Rapoport, T.A.5
Prinz, W.A.6
Voeltz, G.K.7
-
43
-
-
0025056563
-
Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport
-
Koo, E. H., Sisodia, S. S., Archer, D. R., Martin, L. J., Weidemann, A., Beyreuther, K., Fischer, P., Masters, C. L., and Price, D. L. (1990) Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport. Proc. Natl. Acad. Sci. U.S.A. 87, 1561-1565
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 1561-1565
-
-
Koo, E.H.1
Sisodia, S.S.2
Archer, D.R.3
Martin, L.J.4
Weidemann, A.5
Beyreuther, K.6
Fischer, P.7
Masters, C.L.8
Price, D.L.9
-
44
-
-
84883462681
-
The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques
-
Kandalepas, P. C., Sadleir, K. R., Eimer, W. A., Zhao, J., Nicholson, D. A., and Vassar, R. (2013) The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques. Acta Neuropathol. 126, 329-352
-
(2013)
Acta Neuropathol.
, vol.126
, pp. 329-352
-
-
Kandalepas, P.C.1
Sadleir, K.R.2
Eimer, W.A.3
Zhao, J.4
Nicholson, D.A.5
Vassar, R.6
-
45
-
-
0035818998
-
Kinesin-mediated axonal transport of a membrane compartment containing β-secretase and presenilin-1 requires APP
-
Kamal, A., Almenar-Queralt, A., LeBlanc, J. F., Roberts, E. A., and Goldstein, L. S. (2001) Kinesin-mediated axonal transport of a membrane compartment containing β-secretase and presenilin-1 requires APP. Nature 414, 643-648
-
(2001)
Nature
, vol.414
, pp. 643-648
-
-
Kamal, A.1
Almenar-Queralt, A.2
Leblanc, J.F.3
Roberts, E.A.4
Goldstein, L.S.5
-
46
-
-
13844265969
-
BACE overexpression alters the subcellular processing of APP and inhibits A deposition in vivo
-
Lee, E. B., Zhang, B., Liu, K., Greenbaum, E. A., Doms, R. W., Trojanowski, J. Q., and Lee, V. M. (2005) BACE overexpression alters the subcellular processing of APP and inhibits A deposition in vivo. J. Cell Biol. 168, 291-302
-
(2005)
J. Cell Biol.
, vol.168
, pp. 291-302
-
-
Lee, E.B.1
Zhang, B.2
Liu, K.3
Greenbaum, E.A.4
Doms, R.W.5
Trojanowski, J.Q.6
Lee, V.M.7
-
47
-
-
34347353311
-
Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1
-
Lazarov, O., Morfini, G. A., Pigino, G., Gadadhar, A., Chen, X., Robinson, J., Ho, H., Brady, S. T., and Sisodia, S. S. (2007) Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1. J. Neurosci. 27, 7011-7020
-
(2007)
J. Neurosci.
, vol.27
, pp. 7011-7020
-
-
Lazarov, O.1
Morfini, G.A.2
Pigino, G.3
Gadadhar, A.4
Chen, X.5
Robinson, J.6
Ho, H.7
Brady, S.T.8
Sisodia, S.S.9
-
48
-
-
63849105306
-
The cleavage products of amyloid-β precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites
-
Muresan, V., Varvel, N. H., Lamb, B. T., and Muresan, Z. (2009) The cleavage products of amyloid-β precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites. J. Neurosci. 29, 3565-3578
-
(2009)
J. Neurosci.
, vol.29
, pp. 3565-3578
-
-
Muresan, V.1
Varvel, N.H.2
Lamb, B.T.3
Muresan, Z.4
-
49
-
-
70949085531
-
APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle
-
Szodorai, A., Kuan, Y. H., Hunzelmann, S., Engel, U., Sakane, A., Sasaki, T., Takai, Y., Kirsch, J., Müller, U., Beyreuther, K., Brady, S., Morfini, G., and Kins, S. (2009) APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle. J. Neurosci. 29, 14534-14544
-
(2009)
J. Neurosci.
, vol.29
, pp. 14534-14544
-
-
Szodorai, A.1
Kuan, Y.H.2
Hunzelmann, S.3
Engel, U.4
Sakane, A.5
Sasaki, T.6
Takai, Y.7
Kirsch, J.8
Müller, U.9
Beyreuther, K.10
Brady, S.11
Morfini, G.12
Kins, S.13
-
50
-
-
20044396527
-
Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus. Revisited
-
Lazarov, O., Morfini, G. A., Lee, E. B., Farah, M. H., Szodorai, A., DeBoer, S. R., Koliatsos, V. E., Kins, S., Lee, V. M., Wong, P. C., Price, D. L., Brady, S. T., and Sisodia, S. S. (2005) Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus. Revisited. J. Neurosci. 25, 2386-2395
-
(2005)
J. Neurosci.
, vol.25
, pp. 2386-2395
-
-
Lazarov, O.1
Morfini, G.A.2
Lee, E.B.3
Farah, M.H.4
Szodorai, A.5
Deboer, S.R.6
Koliatsos, V.E.7
Kins, S.8
Lee, V.M.9
Wong, P.C.10
Price, D.L.11
Brady, S.T.12
Sisodia, S.S.13
-
51
-
-
0035800545
-
Presenilin-1 and its N-terminal and C-terminal fragments are transported in the sciatic nerve of rat
-
Kasa, P., Papp, H., and Pakaski, M. (2001) Presenilin-1 and its N-terminal and C-terminal fragments are transported in the sciatic nerve of rat. Brain Res. 909, 159-169
-
(2001)
Brain Res.
, vol.909
, pp. 159-169
-
-
Kasa, P.1
Papp, H.2
Pakaski, M.3
-
52
-
-
84964915731
-
Calsyntenin-1 shelters APP from proteolytic processing during anterograde axonal transport
-
Steuble, M., Diep, T. M., Schätzle, P., Ludwig, A., Tagaya, M., Kunz, B., and Sonderegger, P. (2012) Calsyntenin-1 shelters APP from proteolytic processing during anterograde axonal transport. Biol. Open. 1, 761-774
-
(2012)
Biol. Open.
, vol.1
, pp. 761-774
-
-
Steuble, M.1
Diep, T.M.2
Schätzle, P.3
Ludwig, A.4
Tagaya, M.5
Kunz, B.6
Sonderegger, P.7
-
53
-
-
84863518335
-
Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulatesAβ production
-
Vagnoni, A., Perkinton, M. S., Gray, E. H., Francis, P. T., Noble, W., and Miller, C. C. (2012) Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulatesAβ production. Hum. Mol. Genet. 21, 2845-2854
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 2845-2854
-
-
Vagnoni, A.1
Perkinton, M.S.2
Gray, E.H.3
Francis, P.T.4
Noble, W.5
Miller, C.C.6
-
54
-
-
29144490203
-
To think or not to think. Synaptic activity and A release
-
Schroeder, B. E., and Koo, E. H. (2005) To think or not to think. Synaptic activity and A release. Neuron 48, 873-875
-
(2005)
Neuron
, vol.48
, pp. 873-875
-
-
Schroeder, B.E.1
Koo, E.H.2
-
55
-
-
84863263718
-
Role of APP and A in synaptic physiology
-
Wang, Z., Yang, L., and Zheng, H. (2012) Role of APP and A in synaptic physiology. Curr. Alzheimer Res. 9, 217-226
-
(2012)
Curr. Alzheimer Res.
, vol.9
, pp. 217-226
-
-
Wang, Z.1
Yang, L.2
Zheng, H.3
-
56
-
-
84877919955
-
VPS35 regulates developing mouse hippocampal neuronal morphogenesis by promoting retrograde trafficking of BACE1
-
Wang, C. L., Tang, F. L., Peng, Y., Shen, C. Y., Mei, L., and Xiong, W. C. (2012) VPS35 regulates developing mouse hippocampal neuronal morphogenesis by promoting retrograde trafficking of BACE1. Biol. Open. 1, 1248-1257
-
(2012)
Biol. Open.
, vol.1
, pp. 1248-1257
-
-
Wang, C.L.1
Tang, F.L.2
Peng, Y.3
Shen, C.Y.4
Mei, L.5
Xiong, W.C.6
-
57
-
-
84873617529
-
Preventing formation of reticulon 3 immunoreactive dystrophic neurites improves cognitive function in mice
-
Shi, Q., Prior, M., Zhou, X., Tang, X., He, W., Hu, X., and Yan, R. (2013) Preventing formation of reticulon 3 immunoreactive dystrophic neurites improves cognitive function in mice. J. Neurosci. 33, 3059-3066
-
(2013)
J. Neurosci.
, vol.33
, pp. 3059-3066
-
-
Shi, Q.1
Prior, M.2
Zhou, X.3
Tang, X.4
He, W.5
Hu, X.6
Yan, R.7
-
58
-
-
0037236622
-
Elevatedβ-secretase expression and enzymatic activity detected in sporadic Alzheimer disease
-
Yang, L. B., Lindholm, K., Yan, R., Citron, M., Xia, W., Yang, X. L., Beach, T., Sue, L., Wong, P., Price, D., Li, R., and Shen, Y. (2003) Elevatedβ-secretase expression and enzymatic activity detected in sporadic Alzheimer disease. Nat. Med. 9, 3-4
-
(2003)
Nat. Med.
, vol.9
, pp. 3-4
-
-
Yang, L.B.1
Lindholm, K.2
Yan, R.3
Citron, M.4
Xia, W.5
Yang, X.L.6
Beach, T.7
Sue, L.8
Wong, P.9
Price, D.10
Li, R.11
Shen, Y.12
-
59
-
-
61649114950
-
Site amyloid precursor protein cleaving enzyme 1 (BACE1) as a biological candidate marker of Alzheimer's disease
-
Hampel, H., and Shen, Y. (2009)-Site amyloid precursor protein cleaving enzyme 1 (BACE1) as a biological candidate marker of Alzheimer's disease. Scand. J. Clin. Lab. Invest. 69, 8-12
-
(2009)
Scand. J. Clin. Lab. Invest.
, vol.69
, pp. 8-12
-
-
Hampel, H.1
Shen, Y.2
-
60
-
-
0036260892
-
Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease
-
Holsinger, R. M., McLean, C. A., Beyreuther, K., Masters, C. L., and Evin, G. (2002) Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease. Ann. Neurol. 51, 783-786
-
(2002)
Ann. Neurol.
, vol.51
, pp. 783-786
-
-
Holsinger, R.M.1
McLean, C.A.2
Beyreuther, K.3
Masters, C.L.4
Evin, G.5
-
61
-
-
79958785727
-
APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant
-
Tamayev, R., Matsuda, S., Giliberto, L., Arancio, O., and D'Adamio, L. (2011) APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant. EMBO J. 30, 2501-2509
-
(2011)
EMBO J.
, vol.30
, pp. 2501-2509
-
-
Tamayev, R.1
Matsuda, S.2
Giliberto, L.3
Arancio, O.4
D'adamio, L.5
-
62
-
-
78049506839
-
Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits
-
Tamayev, R., Matsuda, S., Fà, M., Arancio, O., and D'Adamio, L. (2010) Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits. Proc. Natl. Acad. Sci. U.S.A. 107, 20822-20827
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 20822-20827
-
-
Tamayev, R.1
Matsuda, S.2
Fà, M.3
Arancio, O.4
D'adamio, L.5
-
63
-
-
84858123000
-
But not β-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia
-
Tamayev, R., Matsuda, S., Arancio, O., and D'Adamio, L. (2012)- but not β-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia. EMBO Mol. Med. 4, 171-179
-
(2012)
EMBO Mol. Med.
, vol.4
, pp. 171-179
-
-
Tamayev, R.1
Matsuda, S.2
Arancio, O.3
D'adamio, L.4
-
64
-
-
84867766569
-
Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects
-
Rodrigues, E. M., Weissmiller, A. M., and Goldstein, L. S. (2012) Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects. Hum. Mol. Genet. 21, 4587-4601
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 4587-4601
-
-
Rodrigues, E.M.1
Weissmiller, A.M.2
Goldstein, L.S.3
|