Axonal Neuregulin-1 Regulates Myelin Sheath Thickness

Science

Volumn 304, Issue 5671, 2004, Pages 700-703

  Michailov, Galin V ^a   Sereda, Michael W ^a,b   Brinkmann, Bastian G ^a   Fischer, Tobias H ^c   Haug, Bernhard ^b   Birchmeier, Carmen ^d   Role, Lorna ^e   Lai, Cary ^c   Schwab, Markus H ^a   Nave, Klaus Armin ^a,f  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^e Och Spine at New York Presbyterian Hospitals   (United States)

^f Hertie Institute of Multiple Sclerosis Research   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; INFORMATION ANALYSIS; SIGNAL PROCESSING;

IMPULSE CONDUCTION; MUTANTS; MYELINATION; VERTEBRATES;

NEUROLOGY;

ISOPROTEIN; NEU DIFFERENTIATION FACTOR;

BIOLOGY;

ACCURACY; ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; MOUSE; MYELIN SHEATH; MYELINATION; NERVE CONDUCTION; NERVE FIBER; NERVOUS SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; VERTEBRATE;

ANIMALS; AXONS; GANGLIA, SPINAL; GENE TARGETING; GENES, ERBB; GENES, ERBB-2; HETEROZYGOTE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MODELS, NEUROLOGICAL; MYELIN SHEATH; NEURAL CONDUCTION; NEUREGULIN-1; PROTEIN ISOFORMS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECEPTOR, ERBB-3; SCHWANN CELLS; SCIATIC NERVE; SIGNAL TRANSDUCTION;

ANIMALIA; MUS MUSCULUS; VERTEBRATA;

EID: 2342444048     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1095862     Document Type: Article

References (40)

1. S. G. Waxman, Curr. Biol. 7, R406 (1997).
2. S. G. Waxman, Muscle Nerve 3, 141 (1980).
3. H. H. Donaldson, G. W. Hoke, J. Comp. Neurol. 15, 1 (1905).
4. R. L. Friede, R. Bischhausen, Brain Res. 235, 335 (1982).
5. R. L. Friede, Exp. Neurol. 92, 234 (1986).
6. J. P. Fraher et al., Acta Neuropathol. 79, 364 (1990).
7. P. L. Williams, C. P. Wendell-Smith, J. Anat. 109, 505 (1971).
8. E. Pannese et al., Anat. Embryol. 175, 423 (1987).
9. T. Voyvodic, Nature 342, 430 (1989).
10. G. A. Elder, V. L. Friedrich, R. A. Lazzarini, J. Neurosci. Res. 65, 493 (2001).
11. D. L. Falls, Exp. Cell Res. 284, 14 (2003).
12. M. Gassmann, G. Lemke, Curr. Opin. Neurobiol. 7, 87 (1997).
13. Y. Yarden, M. X. Sliwkowski, Nat. Rev. Mol. Cell Biol. 2, 127 (2001).
14. A. Buonanno, G. D. Fischbach, Curr. Opin. Neurobiol. 11, 287 (2001).
15. K. Adikofer, C. Lai. Glia 29, 104 (2000).
16. A. N. Garratt, S. Britsch, C. Birchmeier, Bioessays 22, 987(2000).
17. A. N. Garratt, O. Voiculescu, P. Topilko, P. Charnay, C. Birchmeier, J. Cell Biol. 148, 1035 (2000).
18. G. Lemke, Mol. Cell. Neurosci. 7, 247 (1996).
19. D. Meyer et al., Development 124, 3575 (1997).
20. W. H. Ho, M. P. Armanini, A. Nuijens, H. S. Phillips, P. L. Osheroff, J. Biol. Chem. 270, 14523 (1995).
21. D. Wolpowitz et al., Neuron 25, 79 (2000).
22. Materials and methods are available as supporting material on Science Online.
23. O. Bermingham-McDonogh, Y. T. Xu, M. A. Marchionni, S. S. Scherer, Mol. Cell Neurosci. 10, 184 (1997).
24. G. V. Michailov et al., unpublished data.
25. M. Sereda et al., Neuron 16, 1049 (1996).
26. C. Rosenbaum et al., Exp. Neurol. 148, 604 (1997).
27. P. Caroni, J. Neurosci. Methods 71, 3 (1997).
28. F. H. de Webster, Neurosci. Res. Program Bull. 9, 470 (1971).
29. B. G. Brinkmann et al., unpublished data.
30. J. M. Cosgaya, J. R. Chan, E. M. Shooter, Science 298, 1245 (2002).
31. J. H. O'Neill, J. M. Jacobs, R. W. Gilliatt, M. Babs, Acta Neuropathol. 63, 313 (1984).
32. W. Sandrock et al., Science 276, 599 (1997).
33. J. Salzer, personal communication.
34. H. Colognato et al., Nat. Cell Biol. 4, 833 (2002).
35. G. Zanazzi et al., J. Cell Biol. 152, 1289 (2001).
36. P. Maurel, J. L. Salzer, J. Neurosci. 20, 4635 (2000).
37. K. B. Citri, Exp. Cell Res. 284, 54 (2003).
38. R. J. Balice-Gordon, L. J. Bone, S. S. Scherer, J. Cell Biol. 142, 1095 (1998).
39. J. Bao, D. Wolpowitz, L. W. Role, D. A. Talmage, J. Cell Biol. 161, 1133 (2003).
40. We thank E. Nicksch and A. Fahrenholz for excellent technical help, J. Archelos (Graz) for providing us with P0 antibodies, S. S. Scherer (Pennsylvania) for advice on teased-fiber preparations, J. Salzer (New York) for helpful comments on the manuscript, and members of the Nave lab for discussion. This work was supported by the Deutsche Forschungsgemeinschaft (SFB523), the Hertie Institute of Multiple Sclerosis Research, and by grants of the European Union (to K.-A.N.). M.W.S. was supported in part by the Departments of Clinical Neurophysiology and Neurology at the University of Göttingen, and M.H.S., by the National Multiple Sclerosis Society.