NLRC5 interacts with RIG-I to induce a robust antiviral response against influenza virus infection

European Journal of Immunology

Volumn 45, Issue 3, 2015, Pages 758-772

  Ranjan, Priya ^a   Singh, Neetu ^a   Kumar, Amrita ^a   Neerincx, Andreas ^b   Kremmer, Elisabeth ^c   Cao, Weiping ^a   Davis, William G ^a   Katz, Jacqueline M ^a   Gangappa, Shivaprakash ^a   Lin, Rongtuan ^d   Kufer, Thomas A ^e   Sambhara, Suryaprakash ^a  

^a NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d MCGILL UNIVERSITY   (Canada)

^e UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

Influenza; Interferon; NLRC5; NS1; RIG I Antiviral

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; NONSTRUCTURAL PROTEIN 1; PATTERN RECOGNITION RECEPTOR; PROTEIN NLRC5; RANTES; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; HLA ANTIGEN CLASS 1; NLRC5 PROTEIN, HUMAN; SIGNAL PEPTIDE;

A549 CELL LINE; AMINO TERMINAL SEQUENCE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; EXPRESSION VECTOR; GENE CONTROL; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INFLUENZA A (H1N1); INFLUENZA A VIRUS (A/PUERTO RICO/8/1934(H1N1)); INNATE IMMUNITY; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; VIRUS REPLICATION; EPITHELIUM CELL; GENE EXPRESSION REGULATION; HEK293 CELL LINE; IMMUNOLOGY; INFLUENZA; INFLUENZA VIRUS A; PATHOLOGY; PROTEIN TERTIARY STRUCTURE; RESPIRATORY TRACT MUCOSA; VIROLOGY;

DEAD-BOX RNA HELICASES; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HEK293 CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; INFLUENZA A VIRUS; INFLUENZA, HUMAN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTEIN STRUCTURE, TERTIARY; RESPIRATORY MUCOSA;

EID: 84924600935     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201344412     Document Type: Article

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