Enhanced TLR-induced NF-κB signaling and type I interferon responses in NLRC5 deficient mice

Cell Research

Volumn 22, Issue 5, 2012, Pages 822-835

  Tong, Yanzheng ^a,b,c   Cui, Jun ^a,c   Li, Qingtian ^a,c   Zou, Jia ^a,c   Wang, Helen Y ^a,c,d   Wang, Rong Fu ^a,c,d  

^a CENTER FOR CELL AND GENE THERAPY   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^c HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

innate immune signaling; NF B activation; Nod like receptors; type I interferon signaling

Indexed keywords

HLA ANTIGEN CLASS 1; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERFERON; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 6; IRF3 PROTEIN, MOUSE; LIGAND; LIPOPOLYSACCHARIDE; NLRC5 PROTEIN, MOUSE; SIGNAL PEPTIDE; STAT PROTEIN; TOLL LIKE RECEPTOR;

ANIMAL; ARTICLE; CELL LINE; DENDRITIC CELL; DRUG EFFECT; FIBROBLAST; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; MACROPHAGE; METABOLISM; MOUSE; MOUSE MUTANT; PATHOGENICITY; SIGNAL TRANSDUCTION; VESICULAR STOMATITIS VIRUS;

ANIMALS; CELL LINE; DENDRITIC CELLS; FIBROBLASTS; HISTOCOMPATIBILITY ANTIGENS CLASS I; I-KAPPA B KINASE; IMMUNITY, INNATE; INFLAMMASOMES; INTERFERON REGULATORY FACTOR-3; INTERFERON TYPE I; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, KNOCKOUT; NF-KAPPA B; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; TOLL-LIKE RECEPTORS; VESICULOVIRUS;

MUS; VESICULAR STOMATITIS VIRUS;

EID: 84862007380     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2012.53     Document Type: Article

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