LPS regulates SOCS2 transcription in a type I interferon dependent autocrine-paracrine loop

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Hu, Jin ^a,b   Lou, DaoHua ^a   Carow, Berit ^a   Winerdal, Malin E ^a   Rottenberg, Martin ^a   Wikström, Ann Charlotte ^a   Norstedt, Gunnar ^a   Winqvist, Ola ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; INTERFERON; INTERFERON RECEPTOR; INTERFERON REGULATORY FACTOR 3; LIPOPOLYSACCHARIDE; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; STAT3 PROTEIN; STAT5 PROTEIN; STAT6 PROTEIN; TOLL LIKE RECEPTOR 4; IRF3 PROTEIN, MOUSE; MYD88 PROTEIN, MOUSE; SOCS2 PROTEIN, HUMAN; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CELL NUCLEUS; CONTROLLED STUDY; DENDRITIC CELL; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE INDUCTION; HUMAN; HUMAN CELL; INTERFERON PRODUCTION; MACROPHAGE; MOUSE; NONHUMAN; PARACRINE SIGNALING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATOR GENE; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING 2 GENE; TRANSCRIPTION REGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG EFFECT; GENETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY;

MUS;

ANIMALS; AUTOCRINE COMMUNICATION; CELLS, CULTURED; GENE EXPRESSION REGULATION; HUMANS; INTERFERON REGULATORY FACTOR-3; INTERFERON TYPE I; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; PARACRINE COMMUNICATION; STAT TRANSCRIPTION FACTORS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84856113694     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030166     Document Type: Article

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